PT977562E - Metodos e composicoes para administracao de taxanos - Google Patents
Metodos e composicoes para administracao de taxanosInfo
- Publication number
- PT977562E PT977562E PT99909941T PT99909941T PT977562E PT 977562 E PT977562 E PT 977562E PT 99909941 T PT99909941 T PT 99909941T PT 99909941 T PT99909941 T PT 99909941T PT 977562 E PT977562 E PT 977562E
- Authority
- PT
- Portugal
- Prior art keywords
- compositions
- methods
- tax administration
- taxol
- delivery
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Epoxy Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7745998P | 1998-03-10 | 1998-03-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT977562E true PT977562E (pt) | 2006-05-31 |
Family
ID=22138176
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT99909941T PT977562E (pt) | 1998-03-10 | 1999-03-10 | Metodos e composicoes para administracao de taxanos |
Country Status (17)
Country | Link |
---|---|
US (1) | US20010029264A1 (pt) |
EP (1) | EP0977562B8 (pt) |
JP (1) | JP2001524988A (pt) |
KR (1) | KR20010012363A (pt) |
CN (1) | CN1255852A (pt) |
AT (1) | ATE314844T1 (pt) |
AU (1) | AU762926B2 (pt) |
BR (1) | BR9904856A (pt) |
CA (1) | CA2288240A1 (pt) |
CY (1) | CY1105690T1 (pt) |
DE (1) | DE69929313T2 (pt) |
DK (1) | DK0977562T3 (pt) |
ES (1) | ES2257038T3 (pt) |
IL (1) | IL131217A0 (pt) |
PT (1) | PT977562E (pt) |
WO (1) | WO1999045918A1 (pt) |
ZA (1) | ZA991885B (pt) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6964946B1 (en) * | 1995-10-26 | 2005-11-15 | Baker Norton Pharmaceuticals, Inc. | Oral pharmaceutical compositions containing taxanes and methods of treatment employing the same |
US6245805B1 (en) * | 1995-10-26 | 2001-06-12 | Baker Norton Pharmaceuticals, Inc. | Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents |
US6040330A (en) * | 1999-01-08 | 2000-03-21 | Bionumerik Pharmaceuticals, Inc. | Pharmaceutical formulations of taxanes |
EP1479382A1 (en) * | 1999-06-18 | 2004-11-24 | IVAX Research, Inc. | Oral pharmaceutical compositions containing taxanes and methods for treatment employing the same |
US6828346B2 (en) * | 1999-10-25 | 2004-12-07 | Supergen, Inc. | Methods for administration of paclitaxel |
US6136846A (en) | 1999-10-25 | 2000-10-24 | Supergen, Inc. | Formulation for paclitaxel |
AU2001225432A1 (en) * | 2000-01-20 | 2001-07-31 | Supratek Pharma, Inc. | Novel podophyllotoxin compositions |
MXPA01009900A (es) * | 2000-02-02 | 2003-08-20 | Univ Florida State Res Found | Formulaciones de taxano que tienen solubilidad mejorada. |
EP1337273A2 (en) | 2000-11-28 | 2003-08-27 | Transform Pharmaceuticals, Inc. | Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof |
US7115565B2 (en) | 2001-01-18 | 2006-10-03 | Pharmacia & Upjohn Company | Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability |
JP2004520398A (ja) * | 2001-01-18 | 2004-07-08 | ファルマシア・アンド・アップジョン・カンパニー | 経口生物学的利用能が改善されたパクリタキセルの化学療法マイクロエマルジョン組成物 |
US6710195B2 (en) * | 2001-11-26 | 2004-03-23 | Supergen, Inc. | Method for preparing and using polyoxyethylated castor oil in pharmaceutical compositions |
WO2003045357A1 (en) * | 2001-11-27 | 2003-06-05 | Transform Pharmaceuticals, Inc. | Oral pharmaceutical formulations comprising paclitaxel, derivatives and methods of administration thereof |
KR20040066921A (ko) * | 2001-12-20 | 2004-07-27 | 브리스톨-마이어스스퀴브컴파니 | 생체이용률이 향상된 경구 활성 탁산 유도체의 제약조성물 |
EP1340497A1 (en) * | 2002-03-01 | 2003-09-03 | Novagali Sas | Self emulsifying drug delivery systems for poorly soluble drugs |
ES2283756T3 (es) * | 2002-03-01 | 2007-11-01 | Novagali Pharma Sa | Sistemas autoemulsionantes de administracion de farmaco para taxoides. |
RU2344821C2 (ru) * | 2002-07-30 | 2009-01-27 | Уайт | Парентеральные композиции, содержащие гидроксиэфиры рапамицина |
DE10244847A1 (de) | 2002-09-20 | 2004-04-01 | Ulrich Prof. Dr. Speck | Medizinische Vorrichtung zur Arzneimittelabgabe |
AU2002350719A1 (en) | 2002-11-29 | 2004-06-23 | Janssen Pharmaceutica N.V. | Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base |
US20040127551A1 (en) * | 2002-12-27 | 2004-07-01 | Kai Zhang | Taxane-based compositions and methods of use |
DE60331367D1 (de) * | 2002-12-30 | 2010-04-01 | Angiotech Int Ag | Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung |
WO2004091506A2 (en) * | 2003-04-10 | 2004-10-28 | Ivax Research, Inc. | Taxane-based compositions and methods of use |
EP1498120A1 (en) * | 2003-07-18 | 2005-01-19 | Aventis Pharma S.A. | Semi-solid formulations for the oral administration of taxoids |
EP1510206A1 (en) * | 2003-08-29 | 2005-03-02 | Novagali Pharma SA | Self-nanoemulsifying oily formulation for the administration of poorly water-soluble drugs |
CA2552925A1 (en) * | 2004-01-30 | 2005-08-18 | Pfizer Italia S.R.L. | Semisolid matrix pharmaceutical formulations |
WO2005074889A1 (en) * | 2004-02-03 | 2005-08-18 | Dinesh Shantilal Patel | Novel compositions of taxol derivatives and the process for the manufacture thereof |
US7989490B2 (en) * | 2004-06-02 | 2011-08-02 | Cordis Corporation | Injectable formulations of taxanes for cad treatment |
US8003122B2 (en) | 2004-03-31 | 2011-08-23 | Cordis Corporation | Device for local and/or regional delivery employing liquid formulations of therapeutic agents |
US7345093B2 (en) | 2004-04-27 | 2008-03-18 | Formatech, Inc. | Methods of enhancing solubility of compounds |
US7659310B2 (en) | 2004-04-27 | 2010-02-09 | Formatech, Inc. | Methods of enhancing solubility of agents |
WO2006039268A2 (en) * | 2004-09-30 | 2006-04-13 | Eastman Chemical Company | Pharmaceutical formulations containing vitamin e tpgs molecules that solubilize lipophilic drugs without significant efflux inhibition, and use of such formulations |
US20070167422A1 (en) * | 2006-01-18 | 2007-07-19 | Yu Kwok S | Pharmaceutical compositions comprising 17-allylamino-17-demethoxygeldanamycin |
CN101998828A (zh) * | 2008-03-28 | 2011-03-30 | 粒子科学有限公司 | 用于使治疗剂增溶的药物溶液和方法 |
US8409601B2 (en) | 2008-03-31 | 2013-04-02 | Cordis Corporation | Rapamycin coated expandable devices |
CN102000052B (zh) * | 2008-06-25 | 2012-12-12 | 重庆市中药研究院 | 紫杉醇及其衍生物在制药中的应用 |
US20110070293A1 (en) | 2009-09-23 | 2011-03-24 | Javeri Indu | Methods for the Preparation of Liposomes Comprising Docetaxel |
US10143652B2 (en) | 2009-09-23 | 2018-12-04 | Curirx Inc. | Methods for the preparation of liposomes |
US20120065255A1 (en) * | 2009-10-19 | 2012-03-15 | Nagesh Palepu | Cabazitaxel formulations and methods of preparing thereof |
MX341082B (es) | 2010-05-03 | 2016-08-08 | Teikoku Pharma Usa Inc | Formulaciones de pro-emulsion de taxano no acuosas y metodos para hacer y usar las mismas. |
ES2632979T3 (es) * | 2011-01-10 | 2017-09-18 | Celgene Corporation | Formas de dosificación oral de {2-[(1S)-1-(3-etoxi-4-metoxi-fenil)-2-metanosulfonil-etil]-3-oxo-2,3-dihidro-1H-isoindol-4-il}-amida de ácido ciclopropanocarboxílico |
JO3685B1 (ar) | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
CN107683131B (zh) | 2015-06-04 | 2021-09-28 | 克里蒂泰克公司 | 紫杉烷颗粒及其用途 |
EP3324930A2 (en) | 2015-09-16 | 2018-05-30 | DFB Soria, LLC | Delivery of drug nanoparticles and methods of use thereof |
DK3439635T3 (da) | 2016-04-04 | 2021-03-08 | Crititech Inc | Formuleringer til behandling af fast tumor |
WO2018170196A1 (en) | 2017-03-15 | 2018-09-20 | Dfb Soria, Llc | Topical therapy for the treatment of skin malignancies using nanoparticles of taxanes |
CN110730679A (zh) | 2017-06-09 | 2020-01-24 | 克里蒂泰克公司 | 囊内注射抗肿瘤颗粒治疗上皮囊肿 |
US10398646B2 (en) | 2017-06-14 | 2019-09-03 | Crititech, Inc. | Methods for treating lung disorders |
RU2020110399A (ru) | 2017-10-03 | 2021-11-09 | Крититек, Инк. | Местная доставка противоопухолевых частиц в комбинации с системной доставкой иммунотерапевтических агентов для лечения рака |
CN112165949A (zh) | 2018-03-16 | 2021-01-01 | Dfb索里亚有限责任公司 | 使用紫杉烷纳米颗粒治疗宫颈上皮内瘤变(cin)和宫颈癌的局部疗法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4228162A (en) * | 1979-07-09 | 1980-10-14 | Research Corporation | Dimethyl isosorbide in liquid formulation of aspirin |
US4578391A (en) * | 1982-01-20 | 1986-03-25 | Yamanouchi Pharmaceutical Co., Ltd. | Oily compositions of antitumor drugs |
US4942184A (en) * | 1988-03-07 | 1990-07-17 | The United States Of America As Represented By The Department Of Health And Human Services | Water soluble, antineoplastic derivatives of taxol |
US4960790A (en) * | 1989-03-09 | 1990-10-02 | University Of Kansas | Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof |
ES2119996T3 (es) * | 1992-11-27 | 1998-10-16 | Napro Biotherapeutics Inc | Composicion inyectable que comprende faclitaxel. |
ES2148345T3 (es) * | 1993-10-22 | 2000-10-16 | Hexal Ag | Composicion farmaceutica con ciclosporina a, un derivado de vitamina e y un emulsionante. |
US5877205A (en) * | 1996-06-28 | 1999-03-02 | Board Of Regents, The University Of Texas System | Parenteral paclitaxel in a stable non-toxic formulation |
US6458373B1 (en) * | 1997-01-07 | 2002-10-01 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
-
1998
- 1998-03-10 IL IL13121798A patent/IL131217A0/xx unknown
-
1999
- 1999-03-09 ZA ZA9901885A patent/ZA991885B/xx unknown
- 1999-03-10 ES ES99909941T patent/ES2257038T3/es not_active Expired - Lifetime
- 1999-03-10 JP JP54602599A patent/JP2001524988A/ja not_active Ceased
- 1999-03-10 CA CA002288240A patent/CA2288240A1/en not_active Abandoned
- 1999-03-10 AU AU29022/99A patent/AU762926B2/en not_active Ceased
- 1999-03-10 DK DK99909941T patent/DK0977562T3/da active
- 1999-03-10 WO PCT/US1999/005151 patent/WO1999045918A1/en active IP Right Grant
- 1999-03-10 CN CN99800022A patent/CN1255852A/zh active Pending
- 1999-03-10 EP EP99909941A patent/EP0977562B8/en not_active Expired - Lifetime
- 1999-03-10 AT AT99909941T patent/ATE314844T1/de not_active IP Right Cessation
- 1999-03-10 PT PT99909941T patent/PT977562E/pt unknown
- 1999-03-10 BR BR9904856-6A patent/BR9904856A/pt not_active Application Discontinuation
- 1999-03-10 KR KR19997010315A patent/KR20010012363A/ko not_active Application Discontinuation
- 1999-03-10 DE DE69929313T patent/DE69929313T2/de not_active Expired - Fee Related
-
2001
- 2001-02-28 US US09/795,626 patent/US20010029264A1/en not_active Abandoned
-
2006
- 2006-03-29 CY CY20061100438T patent/CY1105690T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
MX9910340A (en) | 2000-04-01 |
EP0977562B1 (en) | 2006-01-04 |
KR20010012363A (ko) | 2001-02-15 |
ATE314844T1 (de) | 2006-02-15 |
CN1255852A (zh) | 2000-06-07 |
DE69929313D1 (de) | 2006-03-30 |
DK0977562T3 (da) | 2006-05-01 |
AU762926B2 (en) | 2003-07-10 |
AU2902299A (en) | 1999-09-27 |
WO1999045918A1 (en) | 1999-09-16 |
DE69929313T2 (de) | 2006-08-17 |
CY1105690T1 (el) | 2010-12-22 |
US20010029264A1 (en) | 2001-10-11 |
ZA991885B (en) | 1999-09-10 |
CA2288240A1 (en) | 1999-09-16 |
IL131217A0 (en) | 2001-01-28 |
ES2257038T3 (es) | 2006-07-16 |
JP2001524988A (ja) | 2001-12-04 |
EP0977562A1 (en) | 2000-02-09 |
BR9904856A (pt) | 2000-07-18 |
EP0977562B8 (en) | 2006-04-26 |
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