ATE491781T1 - Magnetische zelle und verfahren zur verwendung davon - Google Patents

Magnetische zelle und verfahren zur verwendung davon

Info

Publication number
ATE491781T1
ATE491781T1 AT04746441T AT04746441T ATE491781T1 AT E491781 T1 ATE491781 T1 AT E491781T1 AT 04746441 T AT04746441 T AT 04746441T AT 04746441 T AT04746441 T AT 04746441T AT E491781 T1 ATE491781 T1 AT E491781T1
Authority
AT
Austria
Prior art keywords
cell
magnetic
magnetic particle
retained
chondrocyte
Prior art date
Application number
AT04746441T
Other languages
English (en)
Inventor
Mitsuo Ochi
Original Assignee
Eisai R&D Man Co Ltd
Mitsuo Ochi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd, Mitsuo Ochi filed Critical Eisai R&D Man Co Ltd
Application granted granted Critical
Publication of ATE491781T1 publication Critical patent/ATE491781T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0006—Modification of the membrane of cells, e.g. cell decoration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Magnetic Record Carriers (AREA)
AT04746441T 2003-06-30 2004-06-25 Magnetische zelle und verfahren zur verwendung davon ATE491781T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003188626 2003-06-30
PCT/JP2004/008972 WO2005001070A1 (ja) 2003-06-30 2004-06-25 磁性細胞およびその使用方法

Publications (1)

Publication Number Publication Date
ATE491781T1 true ATE491781T1 (de) 2011-01-15

Family

ID=33549759

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04746441T ATE491781T1 (de) 2003-06-30 2004-06-25 Magnetische zelle und verfahren zur verwendung davon

Country Status (9)

Country Link
US (2) US7971592B2 (de)
EP (3) EP2360240A1 (de)
JP (1) JP3889026B2 (de)
KR (2) KR100799060B1 (de)
CN (2) CN101173250B (de)
AT (1) ATE491781T1 (de)
DE (1) DE602004030579D1 (de)
ES (1) ES2358176T3 (de)
WO (1) WO2005001070A1 (de)

Families Citing this family (36)

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CN101173250B (zh) * 2003-06-30 2011-01-26 卫材R&D管理有限公司 磁性细胞及其使用方法
ITRM20030376A1 (it) 2003-07-31 2005-02-01 Univ Roma Procedimento per l'isolamento e l'espansione di cellule staminali cardiache da biopsia.
GB0405552D0 (en) * 2004-03-12 2004-04-21 Magnet Attraction Ltd Methods for the targetted delivery of biological molecules
US11660317B2 (en) 2004-11-08 2023-05-30 The Johns Hopkins University Compositions comprising cardiosphere-derived cells for use in cell therapy
JP2007151605A (ja) * 2005-11-30 2007-06-21 Mitsuo Ochi 磁気誘導装置および磁性複合体の誘導システム
US20090220463A1 (en) * 2006-01-19 2009-09-03 Doo-Sik Kim Pharmaceutical Composition For Treating Vascular-Related Diseases Comprising Peptide
CN101379082A (zh) 2006-01-19 2009-03-04 爱吉恩公司 治疗血管相关疾病的包含肽的药物组合物
US9101581B2 (en) 2008-10-27 2015-08-11 Eyegene Inc. Method for treating vascular-related disease
US8544474B2 (en) * 2007-12-20 2013-10-01 Mayo Foundation For Medical Education And Research Systems and methods for magnetic-assisted therapeutic agent delivery
WO2009100137A2 (en) * 2008-02-04 2009-08-13 University Of Miami Magnetic cells for localizing delivery and tissue repair
DE102009043537B4 (de) 2009-09-30 2012-03-22 Siemens Aktiengesellschaft Verfahren und Anordnung zur Bestimmung von Zell-Vitalitäten
WO2011049236A1 (ja) 2009-10-23 2011-04-28 学校法人芝浦工業大学 磁気誘導システムとその動作方法
KR101028875B1 (ko) * 2010-02-12 2011-04-12 메디스커브 주식회사 세포 내에서 세포내 물질의 생리활성 기능을 조절하는 조절물질을 검출하는 방법
US9845457B2 (en) 2010-04-30 2017-12-19 Cedars-Sinai Medical Center Maintenance of genomic stability in cultured stem cells
US9249392B2 (en) 2010-04-30 2016-02-02 Cedars-Sinai Medical Center Methods and compositions for maintaining genomic stability in cultured stem cells
KR101983229B1 (ko) 2010-07-23 2019-05-29 삼성디스플레이 주식회사 유기 발광 표시 장치 및 그의 제조 방법
WO2013184527A1 (en) 2012-06-05 2013-12-12 Capricor, Inc. Optimized methods for generation of cardiac stem cells from cardiac tissue and their use in cardiac therapy
JP2015529471A (ja) * 2012-06-13 2015-10-08 コーポレイション ドゥレ エコール ポリテクニーク ドゥ モンレアル 磁気感応体の集団化および制御
DE102012212427A1 (de) * 2012-07-16 2014-01-16 Leibniz-Institut Für Festkörper- Und Werkstoffforschung Dresden E.V. Verfahren zur kontrollierten Bewegung von motilen Zellen in flüssigen oder gasförmigen Medien
CA2881394C (en) 2012-08-13 2024-05-14 Cedars-Sinai Medical Center Exosomes and micro-ribonucleic acids for tissue regeneration
WO2014074475A1 (en) * 2012-11-07 2014-05-15 Emmetrope Ophthalmics Llc Magnetic eye shields and methods of treatment and diagnosis using the same
EP2931367A4 (de) * 2012-12-14 2016-06-15 Medivation Technologies Inc Magnetische rückhaltung für regenerative zellen für die wundreparatur
WO2016013660A1 (ja) * 2014-07-24 2016-01-28 凸版印刷株式会社 脂質膜構造体、脂質膜構造体固定化担体、及び胞体の融合方法
AU2015327812B2 (en) 2014-10-03 2021-04-15 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy
US11253551B2 (en) 2016-01-11 2022-02-22 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction
US11351200B2 (en) 2016-06-03 2022-06-07 Cedars-Sinai Medical Center CDC-derived exosomes for treatment of ventricular tachyarrythmias
WO2018057542A1 (en) 2016-09-20 2018-03-29 Cedars-Sinai Medical Center Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders
KR101927196B1 (ko) * 2016-10-26 2018-12-11 전남대학교 산학협력단 자기구동 관절연골 재생 시스템
JP7336769B2 (ja) 2017-04-19 2023-09-01 シーダーズ―シナイ メディカル センター 骨格筋ジストロフィーを治療する方法及び組成物
EP3665269B1 (de) 2017-08-08 2021-09-15 Greiner Bio-One North America, Inc. Verwendung von magnetischen zellen zur manipulation nichtmagnetischer zellen
WO2019126068A1 (en) 2017-12-20 2019-06-27 Cedars-Sinai Medical Center Engineered extracellular vesicles for enhanced tissue delivery
KR102114300B1 (ko) 2018-04-16 2020-05-22 전남대학교 산학협력단 최소 침습 골연골 재생용 자기 구동 마이크로지지체
JP6652608B2 (ja) * 2018-09-13 2020-02-26 ポリヴェイラー，リミテッド パートナーシップ 磁気感応体の集団化および制御
KR102248370B1 (ko) 2018-12-11 2021-05-07 (주)바이오트코리아 세포 탑재용 모듈 장치
KR102227821B1 (ko) * 2020-12-04 2021-03-15 연세대학교 산학협력단 유동관 형상 제어용 자성 세포, 이의 제조방법, 유동관 형상 제어 시스템 및 자성 세포를 이용한 인공지능 유동관 형상 제어계획 수립 시스템
WO2022203384A1 (ko) * 2021-03-23 2022-09-29 연세대학교 산학협력단 자성 세포의 적정 주입량을 결정하기 위한 정보 제공 방법

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JP2699038B2 (ja) 1992-02-21 1998-01-19 株式会社ノエビア 温度感受性リポソーム
JP2642025B2 (ja) 1992-10-23 1997-08-20 科学技術振興事業団 磁性微粒子による細胞への生体物質導入方法及び磁気による細胞の選択的濃縮・分離法
JP4791616B2 (ja) 1997-09-19 2011-10-12 克郎 立花 薬物坦持体及びその使用方法
US5655546A (en) * 1995-06-07 1997-08-12 Halpern; Alan A. Method for cartilage repair
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US6203487B1 (en) * 1997-12-31 2001-03-20 Thomas Jefferson University Use of magnetic particles in the focal delivery of cells
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CN101173250B (zh) * 2003-06-30 2011-01-26 卫材R&D管理有限公司 磁性细胞及其使用方法

Also Published As

Publication number Publication date
WO2005001070A1 (ja) 2005-01-06
ES2358176T3 (es) 2011-05-06
KR100799060B1 (ko) 2008-01-29
EP2182053A1 (de) 2010-05-05
US20060264690A1 (en) 2006-11-23
EP1650293A4 (de) 2006-07-26
CN1742080A (zh) 2006-03-01
EP1650293B1 (de) 2010-12-15
JPWO2005001070A1 (ja) 2006-07-27
EP2360240A1 (de) 2011-08-24
CN100374550C (zh) 2008-03-12
US7971592B2 (en) 2011-07-05
US8701676B2 (en) 2014-04-22
CN101173250B (zh) 2011-01-26
US20100132722A1 (en) 2010-06-03
DE602004030579D1 (de) 2011-01-27
JP3889026B2 (ja) 2007-03-07
KR100743341B1 (ko) 2007-07-26
EP1650293A1 (de) 2006-04-26
KR20050084315A (ko) 2005-08-26
CN101173250A (zh) 2008-05-07
KR20070047849A (ko) 2007-05-07

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