ATE4778T1 - Verfahren zur herstellung von hepatitisvirusantik\rpern und zellstaemme hierfuer. - Google Patents
Verfahren zur herstellung von hepatitisvirusantik\rpern und zellstaemme hierfuer.Info
- Publication number
- ATE4778T1 ATE4778T1 AT80106378T AT80106378T ATE4778T1 AT E4778 T1 ATE4778 T1 AT E4778T1 AT 80106378 T AT80106378 T AT 80106378T AT 80106378 T AT80106378 T AT 80106378T AT E4778 T1 ATE4778 T1 AT E4778T1
- Authority
- AT
- Austria
- Prior art keywords
- hepatitis virus
- production
- cell strain
- virus antibody
- monoclonal antibodies
- Prior art date
Links
- 208000006454 hepatitis Diseases 0.000 title abstract 4
- 231100000283 hepatitis Toxicity 0.000 title abstract 4
- 241000700605 Viruses Species 0.000 title abstract 3
- 210000004027 cell Anatomy 0.000 abstract 2
- 206010035226 Plasma cell myeloma Diseases 0.000 abstract 1
- 210000000628 antibody-producing cell Anatomy 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 210000004754 hybrid cell Anatomy 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 210000004698 lymphocyte Anatomy 0.000 abstract 1
- 201000000050 myeloid neoplasm Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/948—Microorganisms using viruses or cell lines
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/861—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving IgG3, IgG4, IgA, or IgY
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/863—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving IgM
- Y10S530/864—Monoclonal
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/086,947 US4271145A (en) | 1979-10-22 | 1979-10-22 | Process for producing antibodies to hepatitis virus and cell lines therefor |
EP80106378A EP0027657B1 (de) | 1979-10-22 | 1980-10-20 | Verfahren zur Herstellung von Hepatitisvirus-Antikörpern und Zellstämme hierfür |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE4778T1 true ATE4778T1 (de) | 1983-10-15 |
Family
ID=22201916
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT80106378T ATE4778T1 (de) | 1979-10-22 | 1980-10-20 | Verfahren zur herstellung von hepatitisvirusantik\rpern und zellstaemme hierfuer. |
Country Status (5)
Country | Link |
---|---|
US (1) | US4271145A (de) |
EP (1) | EP0027657B1 (de) |
JP (2) | JPS5673029A (de) |
AT (1) | ATE4778T1 (de) |
DE (1) | DE3065072D1 (de) |
Families Citing this family (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3177290T2 (de) * | 1980-04-09 | 1993-04-15 | British Tech Group | Monoklonale antikoerper gegen hepatitis-b-virus. |
US5204095A (en) * | 1980-04-09 | 1993-04-20 | National Research Development Corporation | Monoclonal antibodies against hepatitis B virus |
US4486530A (en) * | 1980-08-04 | 1984-12-04 | Hybritech Incorporated | Immunometric assays using monoclonal antibodies |
US4879219A (en) * | 1980-09-19 | 1989-11-07 | General Hospital Corporation | Immunoassay utilizing monoclonal high affinity IgM antibodies |
US4973669A (en) * | 1980-09-19 | 1990-11-27 | Massachusetts General Hospital | Monoclonal IgM antibody with specificity against hepatitis B surface antigen |
US4582797A (en) * | 1980-09-25 | 1986-04-15 | The Salk Institute For Biological Studies | Monoclonal antibodies specific for human hematopoietic cell surface glycoproteins |
US4831124A (en) * | 1980-12-10 | 1989-05-16 | Research Corporation Technologies | Recombinant cDNA construction method and hybrid nucleotides useful in cloning |
US4837167A (en) * | 1981-01-30 | 1989-06-06 | Centocor, Inc. | Immunoassay for multi-determinant antigens using high-affinity |
DE3270830D1 (en) * | 1981-01-30 | 1986-06-05 | Centocor Inc | Immunoassay for multi-determinant antigens |
US4719177A (en) * | 1981-04-20 | 1988-01-12 | Massachusetts Institute Of Technology | Production of complementary DNA representing RNA viral sequences by recombinant DNA methods and uses therefor |
US4474893A (en) * | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies |
FR2509178A1 (fr) * | 1981-07-10 | 1983-01-14 | Jean Loup Romet Lemonne | Antigene tumoral associe au cancer primitif de foie et anticorps correspondants hbv-t ag et anti-hbv-t. applications a la production d'un antigene reactif et d'immunserums specifiques en vue du diagnostic precoce et de la mise au point d'une therapeutique du cancer primitif du foie |
GB2115005B (en) * | 1981-12-03 | 1984-11-14 | Cancer Research Campaign | Anti rat liver monoclonal antibody |
US4455296A (en) * | 1982-02-02 | 1984-06-19 | Board Of Regents, The University Of Texas System | Hybrid cell lines producing monoclonal antibodies directed against Haemophilus influenzae |
EP0101731A1 (de) * | 1982-02-23 | 1984-03-07 | President And Fellows Of Harvard College | Abschwächen von impfstoffen mittels monoklonaler antikörper |
US4792601A (en) * | 1982-03-01 | 1988-12-20 | The General Hospital Corporation | Monoclonal antibody to mullerian inhibiting substance |
US4487833A (en) * | 1982-03-01 | 1984-12-11 | The General Hospital Corporation | Method of preparing hybridomas and of purifying immunogenic materials |
US4618585A (en) * | 1982-03-18 | 1986-10-21 | Board Of Regents, The University Of Texas System | Hybridoma cell lines producing monoclonal antibodies directed against cervical cancer cells |
JPS58183629A (ja) * | 1982-04-21 | 1983-10-26 | Eisai Co Ltd | 非a非b型肝炎関連モノクロナ−ル抗体および診断薬 |
US4628027A (en) * | 1982-05-19 | 1986-12-09 | Molecular Engineering Associates, Ltd. | Vitro diagnostic methods using monoclonal antibodies against connective tissue proteins |
US4514498A (en) * | 1982-05-26 | 1985-04-30 | The Board Of Regents, The University Of Texas System | Hybrid cell lines producing monoclonal antibodies directed against Treponema |
DE3379055D1 (en) * | 1982-06-09 | 1989-03-02 | Asahi Chemical Ind | Method for producing human antibody |
US4535057A (en) * | 1982-07-26 | 1985-08-13 | Amf Incorporated | Immunoassay employing monoclonal herpes simplex antibody and biotin-avidin detection system |
US4870026A (en) * | 1982-09-16 | 1989-09-26 | The General Hospital Corporation | Non-A, non-B. hepatitis, virus, methods of identification purification, characterization, diagnosis and immunization |
EP0119259A4 (de) * | 1982-09-16 | 1988-08-04 | Gen Hospital Corp | Nicht a, nicht b, hepatitis-virus, verfahren zur bestimmung, reinigung, kennzeichnung, diagnose und immunisierung. |
US4714613A (en) * | 1982-09-30 | 1987-12-22 | The Albert Einstein College Of Medicine Of Yeshiva University | Method of suppressing cell growth by immunotherapy |
US4689299A (en) * | 1982-09-30 | 1987-08-25 | University Of Rochester | Human monoclonal antibodies against bacterial toxins |
CA1262238A (en) | 1982-09-30 | 1989-10-10 | Richard Insel | Human monoclonal antibodies against bacterial toxins |
US4613459A (en) * | 1982-10-20 | 1986-09-23 | Dana-Farber Cancer Institute | Lymphocyte growth factor |
US4767710A (en) * | 1982-12-17 | 1988-08-30 | The United States Of America As Represented By The United States Department Of Energy | Cell lines for the production of monoclonal antibodies to human glycophorin A |
US4752582A (en) * | 1982-12-17 | 1988-06-21 | The United States Of America As Represented By The United States Department Of Energy | Monoclonal antibodies to human glycophorin A and cell lines for the production thereof |
JPH03271235A (ja) * | 1983-04-08 | 1991-12-03 | Kureha Chem Ind Co Ltd | 抗カンジダ菌抗体分泌ハイブリドーマ |
US5057598A (en) * | 1983-05-06 | 1991-10-15 | Centocor, Inc. | Monoclonal antibodies reactive with endotoxin core |
US4713325A (en) * | 1983-06-14 | 1987-12-15 | The Regents Of The University Of California | Hybridomas producing monoclonal antibodies specific for FeLV p27 |
US4652522A (en) * | 1983-07-05 | 1987-03-24 | The University Of Pennsylvania | Continuous lymphocyte cell lines, their production and use |
US4614793A (en) * | 1983-10-14 | 1986-09-30 | Merck & Co., Inc. | Hepatitis A--subunit antigen |
US4468346A (en) * | 1983-10-27 | 1984-08-28 | The United States Of America As Represented By The Secretary Of Agriculture | Monoclonal antibodies to porcine immunoglobulins |
US4469630A (en) * | 1983-11-25 | 1984-09-04 | J. T. Baker Chemical Co. | Purification of monoclonal antibodies |
US4604235A (en) * | 1984-05-23 | 1986-08-05 | J. T. Baker Chemical Company | Purification of monoclonal antibodies |
US5001056A (en) * | 1984-06-08 | 1991-03-19 | The Johns Hopkins University | Preparation of monoclonal antibodies |
US4624918A (en) * | 1984-07-09 | 1986-11-25 | Genentech, Inc. | Purification process for hepatitis surface antigen and product thereof |
JPS61104796A (ja) * | 1984-10-26 | 1986-05-23 | Chemo Sero Therapeut Res Inst | モノクロ−ナル抗体の製造方法 |
GB8431171D0 (en) * | 1984-12-11 | 1985-01-23 | Technology Licence Co Ltd | Monoclonal antibodies |
DE229046T1 (de) * | 1985-03-30 | 1987-12-17 | Marc Genf/Geneve Ballivet | Verfahren zum erhalten von dns, rns, peptiden, polypeptiden oder proteinen durch dns-rekombinant-verfahren. |
US4818688A (en) * | 1986-11-21 | 1989-04-04 | E. I. Du Pont De Nemours And Company | Assays for antibody to hepatitis B core antigen |
US5157113A (en) * | 1987-08-10 | 1992-10-20 | Miles Inc. | Removal of nucleic acids from monoclonal antibody preparations |
US5079173A (en) * | 1987-08-19 | 1992-01-07 | Shionogi & Co., Ltd. | Methods, hybridomas, monoclonal antibodies and sensitized cells for measuring hbs antigen |
US4959310A (en) * | 1987-09-28 | 1990-09-25 | The United States Of America As Represented By The Secretary Of Agriculture | Monoclonal antibodies to soybean kunitz trypsin inhibitor and immunoassay methods |
US6171782B1 (en) * | 1987-11-18 | 2001-01-09 | Chiron Corporation | Antibody compositions to HCV and uses thereof |
US5350671A (en) * | 1987-11-18 | 1994-09-27 | Chiron Corporation | HCV immunoassays employing C domain antigens |
US6861212B1 (en) * | 1987-11-18 | 2005-03-01 | Chiron Corporation | NANBV diagnostics and vaccines |
US5053327A (en) * | 1988-09-20 | 1991-10-01 | The United States Of America As Represented By The Secretary Of Agriculture | High affinity monoclonal antibodies to bowman-birk inhibitor and immunoassay methods |
US5077192A (en) * | 1988-10-25 | 1991-12-31 | The General Hospital Corporation | Method of detecting antigenic, nucleic acid-containing macromolecular entities |
US5210077A (en) * | 1989-04-06 | 1993-05-11 | The United States Of America As Represented By The Secretary Of Agriculture | Antibodies to cytokinins having a glycosylated isoprenoid side chain and immunoassay methods |
US5252711A (en) * | 1989-06-01 | 1993-10-12 | The Gillette Company | Monoclonal antibodies useful in deodorizing skin and antibody fragments thereof |
US5118618A (en) * | 1989-10-05 | 1992-06-02 | Foodscience Corporation | Dimethylglycine enhancement of antibody production |
US5550019A (en) * | 1993-05-26 | 1996-08-27 | La Jolla Cancer Research Foundation | Methods of identifying compounds which alter apoptosis |
US5726011A (en) * | 1994-03-31 | 1998-03-10 | Virginia Commonwealth University | Method for diagnosing chronic hepatitis B virus infection |
US5849906A (en) * | 1994-09-02 | 1998-12-15 | Cavalieri; Ercole | Antigenic conjugates of polycyclic aromatic hydrocarbons to nucleosides |
US5965521A (en) * | 1997-02-25 | 1999-10-12 | Eli Lilly Company | Pulsatile delivery of leptin receptor ligands |
EP1728799B1 (de) | 2005-06-02 | 2008-08-20 | Bioptik Technology, Inc. | Human Kinase interacting Protein 2 (KIP2)-related gene variant (KIP2V1) im Zusammenhang mit Prostatakrebs |
US20080076124A1 (en) * | 2006-09-20 | 2008-03-27 | Visgeneer, Inc. | Human Protein Phosphatase With EF-Hands-1(PPEF-1)-Related Gene Variant Associated With T-Cell Lymphoblastic Lymphoma |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5344620A (en) * | 1976-09-30 | 1978-04-21 | Green Cross Corp:The | Recovering of immobilized vaccine and specific antigen |
FI64952C (fi) * | 1977-06-15 | 1984-02-10 | Wistar Inst | Foerfarande foer framstaellning av genetiskt stabila cellinjer |
US4196265A (en) * | 1977-06-15 | 1980-04-01 | The Wistar Institute | Method of producing antibodies |
-
1979
- 1979-10-22 US US06/086,947 patent/US4271145A/en not_active Expired - Lifetime
-
1980
- 1980-10-20 EP EP80106378A patent/EP0027657B1/de not_active Expired
- 1980-10-20 JP JP14585780A patent/JPS5673029A/ja active Pending
- 1980-10-20 AT AT80106378T patent/ATE4778T1/de active
- 1980-10-20 DE DE8080106378T patent/DE3065072D1/de not_active Expired
-
1990
- 1990-03-12 JP JP2060861A patent/JPH034781A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0027657A3 (en) | 1981-10-28 |
JPH034781A (ja) | 1991-01-10 |
US4271145A (en) | 1981-06-02 |
EP0027657A2 (de) | 1981-04-29 |
JPS5673029A (en) | 1981-06-17 |
EP0027657B1 (de) | 1983-09-28 |
DE3065072D1 (en) | 1983-11-03 |
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