DE3584872D1 - Verfahren zur herstellung von monoklonalen antikoerpern gegen hbsag. - Google Patents

Verfahren zur herstellung von monoklonalen antikoerpern gegen hbsag.

Info

Publication number
DE3584872D1
DE3584872D1 DE8585113585T DE3584872T DE3584872D1 DE 3584872 D1 DE3584872 D1 DE 3584872D1 DE 8585113585 T DE8585113585 T DE 8585113585T DE 3584872 T DE3584872 T DE 3584872T DE 3584872 D1 DE3584872 D1 DE 3584872D1
Authority
DE
Germany
Prior art keywords
hbsag
monoclonal antibody
antibody against
producing monoclonal
against hbsag
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585113585T
Other languages
English (en)
Inventor
Yasuyuki Eda
Toshihiro Maeda
Kiyoto Nishiyama
Akira Tashiro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemo Sero Therapeutic Research Institute Kaketsuken
Original Assignee
Chemo Sero Therapeutic Research Institute Kaketsuken
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Sero Therapeutic Research Institute Kaketsuken filed Critical Chemo Sero Therapeutic Research Institute Kaketsuken
Application granted granted Critical
Publication of DE3584872D1 publication Critical patent/DE3584872D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/082—Hepadnaviridae, e.g. hepatitis B virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE8585113585T 1984-10-26 1985-10-25 Verfahren zur herstellung von monoklonalen antikoerpern gegen hbsag. Expired - Lifetime DE3584872D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59226394A JPS61104796A (ja) 1984-10-26 1984-10-26 モノクロ−ナル抗体の製造方法

Publications (1)

Publication Number Publication Date
DE3584872D1 true DE3584872D1 (de) 1992-01-23

Family

ID=16844430

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585113585T Expired - Lifetime DE3584872D1 (de) 1984-10-26 1985-10-25 Verfahren zur herstellung von monoklonalen antikoerpern gegen hbsag.

Country Status (7)

Country Link
US (1) US4883752A (de)
EP (1) EP0179483B1 (de)
JP (1) JPS61104796A (de)
KR (1) KR930001278B1 (de)
AT (1) ATE70310T1 (de)
CA (1) CA1339202C (de)
DE (1) DE3584872D1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5565354A (en) * 1986-09-05 1996-10-15 Sandoz Ltd. Production of human monoclonal antibodies specific for hepatitis B surface antigen
FR2637184A1 (fr) * 1988-10-05 1990-04-06 Inst Nat Sante Rech Med Anticorps monoclonal reconnaissant une region pre-s1 de la grande proteine d'enveloppe du virus de l'hepatite b et ses applications, notamment pour le diagnostic in vitro et le traitement de l'hepatite b
EP0591548A4 (en) * 1992-03-30 1999-04-28 Suntory Ltd Anti-hbs antibody gene and expression plasmid thereof
US6274552B1 (en) 1993-03-18 2001-08-14 Cytimmune Sciences, Inc. Composition and method for delivery of biologically-active factors
SE501668C2 (sv) * 1993-08-06 1995-04-10 Biolin Medical Ab Kvantifiering av CD-transferrin vid hög alkoholkonsumtion med HPLC
US20010055581A1 (en) 1994-03-18 2001-12-27 Lawrence Tamarkin Composition and method for delivery of biologically-active factors
IL118626A0 (en) * 1996-06-11 1996-10-16 Xtl Biopharmaceuticals Limited Anti HBV antibody
IL118625A0 (en) * 1996-06-11 1996-10-16 Xtl Biopharmaceuticals Limited Anti HBV antibodies
ATE317269T1 (de) * 1997-11-10 2006-02-15 Cytimmune Sciences Inc Methoden und zusammensetzungen zur erhöhung der immunantwort und zur herstellung von in-vitro monoklonalen antikörpern (mabs)
US6407218B1 (en) 1997-11-10 2002-06-18 Cytimmune Sciences, Inc. Method and compositions for enhancing immune response and for the production of in vitro mabs
US7229841B2 (en) 2001-04-30 2007-06-12 Cytimmune Sciences, Inc. Colloidal metal compositions and methods
KR100419555B1 (ko) * 2000-05-29 2004-02-19 주식회사유한양행 비형간염바이러스의 에스-표면항원을 인식하는단일클론항체의 가변영역 및 이를 코딩하는 유전자
JP2008504216A (ja) 2003-12-02 2008-02-14 サイトイミューン サイエンシズ インコーポレイテッド モノクローナル抗体の生成のための方法および組成物
US7960145B2 (en) 2007-11-08 2011-06-14 Cytimmune Sciences, Inc. Compositions and methods for generating antibodies
WO2019229699A1 (en) * 2018-05-31 2019-12-05 Novartis Ag Hepatitis b antibodies
CN116731978B (zh) * 2023-08-14 2023-11-28 山东硕景生物科技有限公司 抗人乙肝表面抗原单克隆抗体杂交瘤细胞株、抗人乙肝表面抗原单克隆抗体的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI64952C (fi) * 1977-06-15 1984-02-10 Wistar Inst Foerfarande foer framstaellning av genetiskt stabila cellinjer
US4271145A (en) * 1979-10-22 1981-06-02 The Massachusetts General Hospital Process for producing antibodies to hepatitis virus and cell lines therefor
DE3177290T2 (de) * 1980-04-09 1993-04-15 British Tech Group Monoklonale antikoerper gegen hepatitis-b-virus.
NZ198851A (en) * 1980-11-07 1984-07-31 Wistar Inst Stable,continuous human myeloma cell line capable of hybridisation with antibody-producing cells:production of hybrid cell line
US4594325A (en) * 1981-03-26 1986-06-10 The Regents Of The University Of Calif. High fusion frequency fusible lymphoblastoid cell line
JPS5872526A (ja) * 1981-10-23 1983-04-30 Green Cross Corp:The モノクロ−ルｈｂｓ抗体の製造方法
US4689299A (en) * 1982-09-30 1987-08-25 University Of Rochester Human monoclonal antibodies against bacterial toxins
US4693966A (en) * 1983-03-11 1987-09-15 Sloan-Kettering Institute For Cancer Research Human monoclonal antibodies from lymphocytes of patients with malignant melanoma

Also Published As

Publication number Publication date
KR930001278B1 (ko) 1993-02-25
KR860003021A (ko) 1986-05-19
EP0179483A2 (de) 1986-04-30
US4883752A (en) 1989-11-28
CA1339202C (en) 1997-08-05
JPS61104796A (ja) 1986-05-23
EP0179483B1 (de) 1991-12-11
ATE70310T1 (de) 1991-12-15
EP0179483A3 (en) 1989-03-01

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