ATE457163T1 - Verwendung von ciclesonide zur erhaltung des feinen teilchengrössenanteils von formoterol - Google Patents

Verwendung von ciclesonide zur erhaltung des feinen teilchengrössenanteils von formoterol

Info

Publication number
ATE457163T1
ATE457163T1 AT04735045T AT04735045T ATE457163T1 AT E457163 T1 ATE457163 T1 AT E457163T1 AT 04735045 T AT04735045 T AT 04735045T AT 04735045 T AT04735045 T AT 04735045T AT E457163 T1 ATE457163 T1 AT E457163T1
Authority
AT
Austria
Prior art keywords
ciclesonide
formoterol
maintain
particle size
fine particle
Prior art date
Application number
AT04735045T
Other languages
English (en)
Inventor
Nicholas Heaton
Zoe Heaton
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Application granted granted Critical
Publication of ATE457163T1 publication Critical patent/ATE457163T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/24—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants
    • B65D81/26—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/24—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants
    • B65D81/26—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators
    • B65D81/266—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators for absorbing gases, e.g. oxygen absorbers or desiccants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00—Ancillary equipment
    • A61M2209/06—Packaging for specific medical equipment

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Mechanical Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
AT04735045T 2003-05-28 2004-05-27 Verwendung von ciclesonide zur erhaltung des feinen teilchengrössenanteils von formoterol ATE457163T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0312148.0A GB0312148D0 (en) 2003-05-28 2003-05-28 Stabilized pharmaceutical products
PCT/GB2004/002249 WO2004105727A2 (en) 2003-05-28 2004-05-27 Stabilized pharmaceutical product

Publications (1)

Publication Number Publication Date
ATE457163T1 true ATE457163T1 (de) 2010-02-15

Family

ID=9958829

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04735045T ATE457163T1 (de) 2003-05-28 2004-05-27 Verwendung von ciclesonide zur erhaltung des feinen teilchengrössenanteils von formoterol

Country Status (22)

Country Link
US (4) US7736673B2 (de)
EP (1) EP1626913B1 (de)
JP (1) JP5175048B2 (de)
KR (1) KR20060023539A (de)
CN (1) CN1832890A (de)
AR (1) AR047619A1 (de)
AT (1) ATE457163T1 (de)
AU (1) AU2004243223A1 (de)
BR (1) BRPI0410701A (de)
CA (1) CA2527088C (de)
DE (1) DE602004025463D1 (de)
ES (1) ES2340681T3 (de)
GB (1) GB0312148D0 (de)
MA (1) MA27804A1 (de)
MX (1) MXPA05012757A (de)
NO (1) NO20055443L (de)
PL (1) PL1626913T3 (de)
RS (1) RS20050882A (de)
RU (1) RU2337667C2 (de)
TW (1) TW200509989A (de)
WO (1) WO2004105727A2 (de)
ZA (1) ZA200509099B (de)

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US7879833B2 (en) 2002-12-12 2011-02-01 Nycomed Gmbh Combination medicament
GB0312148D0 (en) * 2003-05-28 2003-07-02 Aventis Pharma Ltd Stabilized pharmaceutical products
EP1635845A1 (de) 2003-06-13 2006-03-22 ALTANA Pharma AG Kombination aus formoterol und ciclesonid
GB0315889D0 (en) 2003-07-08 2003-08-13 Aventis Pharma Ltd Stable pharmaceutical products
EP1803457A1 (de) * 2005-12-30 2007-07-04 Krka Tovarna Zdravil, D.D., Novo Mesto Pharmazeutische Zubereitung, welche Montelukast enthält
SI1976522T2 (sl) * 2005-12-30 2019-11-29 Krka Tovarna Zdravil D D Novo Mesto Farmacevtski sestavek, ki vsebuje montelukast
US20090308772A1 (en) * 2006-03-17 2009-12-17 Abrams William S Moisture-tight primary packaging for a dry powder inhaler
CA2716124A1 (en) * 2008-02-20 2009-08-27 Boehringer Ingelheim International Gmbh Powder inhalers
ES2739352T3 (es) 2009-02-26 2020-01-30 Glaxo Group Ltd Formulaciones farmacéuticas que comprenden 4-{(1R)-2-[(6-{2-[(2,6-diclorobencil)oxi]etoxi}hexil)amino]-1-hidroxietil}-2-(hidroximetil)fenol
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
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KR101783067B1 (ko) * 2010-01-22 2017-09-28 바이엘 헬쓰케어 엘엘씨 정확도 향상용 건조제
WO2011093814A2 (en) * 2010-01-29 2011-08-04 Mahmut Bilgic A pharmaceutical combination comprising formoterol and ciclesonide
EP3461474B1 (de) 2010-08-31 2020-11-11 GlaxoSmithKline Intellectual Property Development Limited Inhalationsmedikamente in trockenpulverform mit feuchtigkeitsregelungseigenschaften und verfahren zu ihrer verabreichung
TR201007250A2 (tr) * 2010-09-01 2012-03-21 Bi̇lgi̇ç Mahmut Selobioz içeren formülasyon.
TWI565943B (zh) * 2011-07-22 2017-01-11 拜耳保健公司 具有增進測量性能之生物感測器乾燥劑系統
KR101851425B1 (ko) 2011-09-02 2018-04-23 네스텍 소시에테아노님 치료 효능 결정을 위한 신호 경로 단백질의 프로파일링
WO2013109212A1 (en) * 2012-01-16 2013-07-25 Mahmut Bilgic Dry powder formulations comprising ciclesonide
KR20130140358A (ko) 2012-06-14 2013-12-24 한미약품 주식회사 살메테롤 지나포산염, 플루티카손 프로피오네이트 및 티오트로피움 브로마이드를 포함하는 흡입 제형용 건조 분말 및 이의 제조방법
EP2954329A1 (de) 2013-02-05 2015-12-16 Nestec S.A. Verfahren zur auswahl einer kombinationstherapie für darmkrebspatienten
CN104644618A (zh) * 2013-11-19 2015-05-27 上海医药工业研究院 一种干粉吸入剂及其制备方法
US11642309B2 (en) * 2017-10-16 2023-05-09 Faes Farma, S.A. Aqueous compositions comprising bilastine and mometasone
US10537585B2 (en) 2017-12-18 2020-01-21 Dexcel Pharma Technologies Ltd. Compositions comprising dexamethasone
WO2023117967A1 (en) * 2021-12-21 2023-06-29 Chiesi Farmaceutici S.P.A. Dry powder formulations filled in an inhaler with improved resistance to humidity

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Also Published As

Publication number Publication date
JP5175048B2 (ja) 2013-04-03
US20120247982A1 (en) 2012-10-04
ZA200509099B (en) 2006-08-30
US20060147537A1 (en) 2006-07-06
MA27804A1 (fr) 2006-03-01
RU2005136869A (ru) 2006-06-10
RS20050882A (en) 2007-12-31
AU2004243223A1 (en) 2004-12-09
CN1832890A (zh) 2006-09-13
CA2527088C (en) 2011-03-01
MXPA05012757A (es) 2006-02-13
AR047619A1 (es) 2006-02-01
WO2004105727A2 (en) 2004-12-09
PL1626913T3 (pl) 2010-07-30
US20100247585A1 (en) 2010-09-30
EP1626913A2 (de) 2006-02-22
TW200509989A (en) 2005-03-16
DE602004025463D1 (de) 2010-03-25
US8163299B2 (en) 2012-04-24
US8029811B2 (en) 2011-10-04
EP1626913B1 (de) 2010-02-10
US7736673B2 (en) 2010-06-15
BRPI0410701A (pt) 2006-06-13
RU2337667C2 (ru) 2008-11-10
ES2340681T3 (es) 2010-06-08
US20110308975A1 (en) 2011-12-22
WO2004105727A3 (en) 2005-06-16
CA2527088A1 (en) 2004-12-09
JP2007504277A (ja) 2007-03-01
US8440210B2 (en) 2013-05-14
GB0312148D0 (en) 2003-07-02
KR20060023539A (ko) 2006-03-14
NO20055443L (no) 2005-11-17

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