DE602004025463D1 - Verwendung von ciclesonide zur erhaltung des feinen teilchengrössenanteils von formoterol - Google Patents
Verwendung von ciclesonide zur erhaltung des feinen teilchengrössenanteils von formoterolInfo
- Publication number
- DE602004025463D1 DE602004025463D1 DE602004025463T DE602004025463T DE602004025463D1 DE 602004025463 D1 DE602004025463 D1 DE 602004025463D1 DE 602004025463 T DE602004025463 T DE 602004025463T DE 602004025463 T DE602004025463 T DE 602004025463T DE 602004025463 D1 DE602004025463 D1 DE 602004025463D1
- Authority
- DE
- Germany
- Prior art keywords
- ciclesonide
- formoterol
- conservation
- fine particle
- particle proportion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/24—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants
- B65D81/26—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/24—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants
- B65D81/26—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators
- B65D81/266—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators for absorbing gases, e.g. oxygen absorbers or desiccants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2209/00—Ancillary equipment
- A61M2209/06—Packaging for specific medical equipment
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0312148.0A GB0312148D0 (en) | 2003-05-28 | 2003-05-28 | Stabilized pharmaceutical products |
PCT/GB2004/002249 WO2004105727A2 (en) | 2003-05-28 | 2004-05-27 | Stabilized pharmaceutical product |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004025463D1 true DE602004025463D1 (de) | 2010-03-25 |
Family
ID=9958829
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004025463T Active DE602004025463D1 (de) | 2003-05-28 | 2004-05-27 | Verwendung von ciclesonide zur erhaltung des feinen teilchengrössenanteils von formoterol |
Country Status (22)
Country | Link |
---|---|
US (4) | US7736673B2 (de) |
EP (1) | EP1626913B1 (de) |
JP (1) | JP5175048B2 (de) |
KR (1) | KR20060023539A (de) |
CN (1) | CN1832890A (de) |
AR (1) | AR047619A1 (de) |
AT (1) | ATE457163T1 (de) |
AU (1) | AU2004243223A1 (de) |
BR (1) | BRPI0410701A (de) |
CA (1) | CA2527088C (de) |
DE (1) | DE602004025463D1 (de) |
ES (1) | ES2340681T3 (de) |
GB (1) | GB0312148D0 (de) |
MA (1) | MA27804A1 (de) |
MX (1) | MXPA05012757A (de) |
NO (1) | NO20055443L (de) |
PL (1) | PL1626913T3 (de) |
RS (1) | RS20050882A (de) |
RU (1) | RU2337667C2 (de) |
TW (1) | TW200509989A (de) |
WO (1) | WO2004105727A2 (de) |
ZA (1) | ZA200509099B (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1572217B1 (de) | 2002-12-12 | 2008-08-20 | Nycomed GmbH | Kombinationsarzneimittel aus r,r-formoterol und ciclesonide |
GB0312148D0 (en) * | 2003-05-28 | 2003-07-02 | Aventis Pharma Ltd | Stabilized pharmaceutical products |
US8435497B2 (en) | 2003-06-13 | 2013-05-07 | Takeda Gmbh | Formoterol of and ciclesonide combination |
GB0315889D0 (en) | 2003-07-08 | 2003-08-13 | Aventis Pharma Ltd | Stable pharmaceutical products |
EP1803457A1 (de) * | 2005-12-30 | 2007-07-04 | Krka Tovarna Zdravil, D.D., Novo Mesto | Pharmazeutische Zubereitung, welche Montelukast enthält |
SI1976522T2 (sl) * | 2005-12-30 | 2019-11-29 | Krka Tovarna Zdravil D D Novo Mesto | Farmacevtski sestavek, ki vsebuje montelukast |
US20090308772A1 (en) * | 2006-03-17 | 2009-12-17 | Abrams William S | Moisture-tight primary packaging for a dry powder inhaler |
EP2254630A1 (de) * | 2008-02-20 | 2010-12-01 | Boehringer Ingelheim International GmbH | Pulverinhalatoren |
EP2400950B1 (de) | 2009-02-26 | 2019-05-22 | Glaxo Group Limited | Pharmazeutische formulierungen enthaltend 4-{(1 r)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol |
GB0921075D0 (en) | 2009-12-01 | 2010-01-13 | Glaxo Group Ltd | Novel combination of the therapeutic agents |
IN2012DN05912A (de) * | 2010-01-22 | 2015-09-18 | Bayer Healthcare Llc | |
US9233788B2 (en) | 2010-01-22 | 2016-01-12 | Bayer Healthcare Llc | Biosensor desiccant system having enhanced measurement performance |
WO2011093814A2 (en) * | 2010-01-29 | 2011-08-04 | Mahmut Bilgic | A pharmaceutical combination comprising formoterol and ciclesonide |
ES2705494T3 (es) | 2010-08-31 | 2019-03-25 | Glaxosmithkline Ip Dev Ltd | Productos farmacológicos para la inhalación de polvo seco que presentan propiedades de control de la humedad y procedimientos de administración de los mismos |
TR201007250A2 (tr) * | 2010-09-01 | 2012-03-21 | Bi̇lgi̇ç Mahmut | Selobioz içeren formülasyon. |
TWI565943B (zh) * | 2011-07-22 | 2017-01-11 | 拜耳保健公司 | 具有增進測量性能之生物感測器乾燥劑系統 |
EP2751562B1 (de) | 2011-09-02 | 2015-09-16 | Nestec S.A. | Profilierung von signalwegproteinen zur bestimmung der therapeutischen wirksamkeit |
WO2013109212A1 (en) * | 2012-01-16 | 2013-07-25 | Mahmut Bilgic | Dry powder formulations comprising ciclesonide |
KR20130140358A (ko) | 2012-06-14 | 2013-12-24 | 한미약품 주식회사 | 살메테롤 지나포산염, 플루티카손 프로피오네이트 및 티오트로피움 브로마이드를 포함하는 흡입 제형용 건조 분말 및 이의 제조방법 |
WO2014122600A1 (en) | 2013-02-05 | 2014-08-14 | Nestec S.A. | Methods of selecting combination therapy for colorectal cancer patients |
CN104644618A (zh) * | 2013-11-19 | 2015-05-27 | 上海医药工业研究院 | 一种干粉吸入剂及其制备方法 |
US11642309B2 (en) * | 2017-10-16 | 2023-05-09 | Faes Farma, S.A. | Aqueous compositions comprising bilastine and mometasone |
US10537585B2 (en) | 2017-12-18 | 2020-01-21 | Dexcel Pharma Technologies Ltd. | Compositions comprising dexamethasone |
WO2023117967A1 (en) * | 2021-12-21 | 2023-06-29 | Chiesi Farmaceutici S.P.A. | Dry powder formulations filled in an inhaler with improved resistance to humidity |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6536427B2 (en) * | 1990-03-02 | 2003-03-25 | Glaxo Group Limited | Inhalation device |
GR1001529B (el) | 1990-09-07 | 1994-03-31 | Elmuquimica Farm Sl | Μέ?οδος για την λήψη νέων 21-εστέρων της 16-17-ακετάλης της πρ να-1,4-διενο-3,20-διόνης. |
AU650953B2 (en) * | 1991-03-21 | 1994-07-07 | Novartis Ag | Inhaler |
SE9302777D0 (sv) | 1993-08-27 | 1993-08-27 | Astra Ab | Process for conditioning substances |
US6586006B2 (en) * | 1994-08-04 | 2003-07-01 | Elan Drug Delivery Limited | Solid delivery systems for controlled release of molecules incorporated therein and methods of making same |
SE9700134D0 (sv) | 1997-01-20 | 1997-01-20 | Astra Ab | New formulation |
DE19541689A1 (de) | 1994-11-14 | 1996-05-15 | Byk Gulden Lomberg Chem Fab | Kombinationsarzneimittel |
US5612053A (en) * | 1995-04-07 | 1997-03-18 | Edward Mendell Co., Inc. | Controlled release insufflation carrier for medicaments |
US6040344A (en) | 1996-11-11 | 2000-03-21 | Sepracor Inc. | Formoterol process |
US6475467B1 (en) | 1998-08-04 | 2002-11-05 | Jago Research Ag | Medicinal aerosol formulations |
EP2266548B1 (de) * | 1998-11-13 | 2020-05-20 | Jagotec AG | Trockenpulver zur inhalation |
FR2786395A1 (fr) * | 1998-12-01 | 2000-06-02 | Virbac Sa | Compositions seches solubles en presence d'eau et evitant la reaction de maillard a l'etat sec, leur preparation et leurs applications |
US6390291B1 (en) * | 1998-12-18 | 2002-05-21 | Smithkline Beecham Corporation | Method and package for storing a pressurized container containing a drug |
US6119853A (en) * | 1998-12-18 | 2000-09-19 | Glaxo Wellcome Inc. | Method and package for storing a pressurized container containing a drug |
US6352152B1 (en) * | 1998-12-18 | 2002-03-05 | Smithkline Beecham Corporation | Method and package for storing a pressurized container containing a drug |
SE9903995D0 (sv) * | 1999-11-03 | 1999-11-03 | Astra Ab | New combination |
GB9928311D0 (en) | 1999-11-30 | 2000-01-26 | Novartis Ag | Organic compounds |
GB0012260D0 (en) * | 2000-05-19 | 2000-07-12 | Astrazeneca Ab | Novel composition |
GB0012261D0 (en) | 2000-05-19 | 2000-07-12 | Astrazeneca Ab | Novel process |
NZ522672A (en) | 2000-05-23 | 2004-07-30 | Glaxo Group Ltd | Aerosol container for formulations of salmeterol xinafoate and preparation process thereof |
GB0015043D0 (en) * | 2000-06-21 | 2000-08-09 | Glaxo Group Ltd | Medicament dispenser |
FI20002177A0 (fi) | 2000-10-02 | 2000-10-02 | Orion Yhtymae Oyj | Uusi yhdistelmä astman hoitoon |
US20030055026A1 (en) | 2001-04-17 | 2003-03-20 | Dey L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
US6472563B1 (en) | 2001-11-09 | 2002-10-29 | Sepracor Inc. | Formoterol tartrate process and polymorph |
NZ532673A (en) | 2001-11-17 | 2008-07-31 | Aventis Pharma Ltd | Package comprising a medicament, a component that gradually releases a gaseous substance and an adsorbent material |
GB0207899D0 (en) | 2002-04-05 | 2002-05-15 | 3M Innovative Properties Co | Formoterol and cielesonide aerosol formulations |
JP2004051502A (ja) * | 2002-07-17 | 2004-02-19 | Jcr Pharmaceuticals Co Ltd | 成長ホルモン含有安定化粉末製剤 |
EP1572217B1 (de) | 2002-12-12 | 2008-08-20 | Nycomed GmbH | Kombinationsarzneimittel aus r,r-formoterol und ciclesonide |
US20060293293A1 (en) | 2003-05-22 | 2006-12-28 | Altana Pharma Ag | Salmeterol and ciclesonide combination |
GB0312148D0 (en) * | 2003-05-28 | 2003-07-02 | Aventis Pharma Ltd | Stabilized pharmaceutical products |
NZ544159A (en) * | 2003-06-06 | 2009-04-30 | Senesco Technologies Inc | Inhibition of apoptosis-specific eIF-5A ("eIF-5A1") with antisense oligonucleotides and siRNAs as anti-inflammatory therapeutics |
US8435497B2 (en) | 2003-06-13 | 2013-05-07 | Takeda Gmbh | Formoterol of and ciclesonide combination |
GB0315889D0 (en) | 2003-07-08 | 2003-08-13 | Aventis Pharma Ltd | Stable pharmaceutical products |
GB0323685D0 (en) | 2003-10-09 | 2003-11-12 | Jagotec Ag | Improvements in or relating to organic compounds |
GB0323684D0 (en) | 2003-10-09 | 2003-11-12 | Jagotec Ag | Improvements in or relating to organic compounds |
-
2003
- 2003-05-28 GB GBGB0312148.0A patent/GB0312148D0/en not_active Ceased
-
2004
- 2004-05-27 WO PCT/GB2004/002249 patent/WO2004105727A2/en active Application Filing
- 2004-05-27 PL PL04735045T patent/PL1626913T3/pl unknown
- 2004-05-27 ES ES04735045T patent/ES2340681T3/es active Active
- 2004-05-27 DE DE602004025463T patent/DE602004025463D1/de active Active
- 2004-05-27 JP JP2006530539A patent/JP5175048B2/ja active Active
- 2004-05-27 CN CNA2004800143546A patent/CN1832890A/zh active Pending
- 2004-05-27 AT AT04735045T patent/ATE457163T1/de not_active IP Right Cessation
- 2004-05-27 CA CA2527088A patent/CA2527088C/en not_active Expired - Fee Related
- 2004-05-27 AU AU2004243223A patent/AU2004243223A1/en not_active Abandoned
- 2004-05-27 RS YUP-2005/0882A patent/RS20050882A/sr unknown
- 2004-05-27 EP EP04735045A patent/EP1626913B1/de active Active
- 2004-05-27 TW TW093115016A patent/TW200509989A/zh unknown
- 2004-05-27 BR BRPI0410701-2A patent/BRPI0410701A/pt not_active IP Right Cessation
- 2004-05-27 MX MXPA05012757A patent/MXPA05012757A/es unknown
- 2004-05-27 RU RU2005136869/13A patent/RU2337667C2/ru not_active IP Right Cessation
- 2004-05-27 KR KR1020057022586A patent/KR20060023539A/ko not_active Application Discontinuation
- 2004-05-28 AR ARP040101868A patent/AR047619A1/es not_active Application Discontinuation
-
2005
- 2005-10-26 US US11/259,495 patent/US7736673B2/en active Active
- 2005-11-10 ZA ZA200509099A patent/ZA200509099B/xx unknown
- 2005-11-11 MA MA28600A patent/MA27804A1/fr unknown
- 2005-11-17 NO NO20055443A patent/NO20055443L/no not_active Application Discontinuation
-
2010
- 2010-04-30 US US12/771,557 patent/US8029811B2/en active Active
-
2011
- 2011-08-26 US US13/219,046 patent/US8163299B2/en active Active
-
2012
- 2012-04-02 US US13/437,569 patent/US8440210B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
AU2004243223A1 (en) | 2004-12-09 |
ATE457163T1 (de) | 2010-02-15 |
US8163299B2 (en) | 2012-04-24 |
PL1626913T3 (pl) | 2010-07-30 |
EP1626913A2 (de) | 2006-02-22 |
NO20055443L (no) | 2005-11-17 |
RU2337667C2 (ru) | 2008-11-10 |
ES2340681T3 (es) | 2010-06-08 |
JP2007504277A (ja) | 2007-03-01 |
US20100247585A1 (en) | 2010-09-30 |
ZA200509099B (en) | 2006-08-30 |
JP5175048B2 (ja) | 2013-04-03 |
CN1832890A (zh) | 2006-09-13 |
EP1626913B1 (de) | 2010-02-10 |
GB0312148D0 (en) | 2003-07-02 |
AR047619A1 (es) | 2006-02-01 |
RU2005136869A (ru) | 2006-06-10 |
TW200509989A (en) | 2005-03-16 |
US20110308975A1 (en) | 2011-12-22 |
WO2004105727A2 (en) | 2004-12-09 |
US8029811B2 (en) | 2011-10-04 |
KR20060023539A (ko) | 2006-03-14 |
US20060147537A1 (en) | 2006-07-06 |
RS20050882A (en) | 2007-12-31 |
BRPI0410701A (pt) | 2006-06-13 |
US7736673B2 (en) | 2010-06-15 |
CA2527088C (en) | 2011-03-01 |
CA2527088A1 (en) | 2004-12-09 |
US20120247982A1 (en) | 2012-10-04 |
MXPA05012757A (es) | 2006-02-13 |
MA27804A1 (fr) | 2006-03-01 |
US8440210B2 (en) | 2013-05-14 |
WO2004105727A3 (en) | 2005-06-16 |
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