ATE411006T1 - Liposomale anordnung für die therapeutische und/oder diagnostische anwendung - Google Patents

Liposomale anordnung für die therapeutische und/oder diagnostische anwendung

Info

Publication number
ATE411006T1
ATE411006T1 AT05749164T AT05749164T ATE411006T1 AT E411006 T1 ATE411006 T1 AT E411006T1 AT 05749164 T AT05749164 T AT 05749164T AT 05749164 T AT05749164 T AT 05749164T AT E411006 T1 ATE411006 T1 AT E411006T1
Authority
AT
Austria
Prior art keywords
liposome
therapeutic
micellar
diagnostic use
active compound
Prior art date
Application number
AT05749164T
Other languages
English (en)
Inventor
Herve Tournier
Roland Hyacinthe
Michel Schneider
Original Assignee
Bracco Research Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Research Sa filed Critical Bracco Research Sa
Application granted granted Critical
Publication of ATE411006T1 publication Critical patent/ATE411006T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0091Purification or manufacturing processes for gene therapy compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806Suspensions, emulsions, colloids, dispersions
    • A61K49/1812Suspensions, emulsions, colloids, dispersions liposomes, polymersomes, e.g. immunoliposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906Drug delivery
    • Y10S977/907Liposome
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Manufacturing & Machinery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
AT05749164T 2004-06-03 2005-05-31 Liposomale anordnung für die therapeutische und/oder diagnostische anwendung ATE411006T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04013141 2004-06-03

Publications (1)

Publication Number Publication Date
ATE411006T1 true ATE411006T1 (de) 2008-10-15

Family

ID=34925239

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05749164T ATE411006T1 (de) 2004-06-03 2005-05-31 Liposomale anordnung für die therapeutische und/oder diagnostische anwendung

Country Status (8)

Country Link
US (1) US7749485B2 (de)
EP (1) EP1750671B1 (de)
JP (1) JP4773430B2 (de)
CN (1) CN1960707B (de)
AT (1) ATE411006T1 (de)
DE (1) DE602005010424D1 (de)
ES (1) ES2313352T3 (de)
WO (1) WO2005117832A1 (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060127468A1 (en) 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening
ATE521355T1 (de) 2004-05-19 2011-09-15 Los Angeles Biomed Res Inst Verwendung eines detergens zur nicht- chirurgischen entfernung von fett
US7754230B2 (en) 2004-05-19 2010-07-13 The Regents Of The University Of California Methods and related compositions for reduction of fat
US20070154403A1 (en) * 2006-01-05 2007-07-05 Thomas Skold Oral, Pulmonary and Transmucosal Delivery Composition
US8114150B2 (en) * 2006-06-14 2012-02-14 Advanced Cardiovascular Systems, Inc. RGD peptide attached to bioabsorbable stents
CA2664944C (en) * 2006-09-28 2016-06-14 Hadasit Medical Research Services & Development Limited Use of glycerophospholipids for joint lubrication
WO2009091531A2 (en) * 2008-01-16 2009-07-23 The General Hospital Corporation Uniform-sized, multi-drug carrying and photosensitive liposomes for advance drug delivery
EP2147684A1 (de) 2008-07-22 2010-01-27 Bracco Imaging S.p.A Selektiv gegen Metallproteasen wirkende Diagnosemittel
US20110229565A1 (en) 2008-09-17 2011-09-22 Karp Jeffrey M Drug Delivery Composition Comprising a Self-Assembled Gelator
AU2009301141B2 (en) 2008-10-07 2015-08-27 Bracco Suisse S.A. Targeting construct comprising anti-polymer antibody and liposomes or microvesicles binding to the same
US8101593B2 (en) 2009-03-03 2012-01-24 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
BRPI1012246A2 (pt) * 2009-03-25 2016-03-29 Novartis Ag composição farmacêutica contendo um fármaco e sirna
JP5491067B2 (ja) * 2009-05-08 2014-05-14 一雄 丸山 リポソーム、リポソームの製造方法、及び医薬組成物
WO2011046934A1 (en) * 2009-10-12 2011-04-21 Au Jessie L-S Methods and compositions for improved delivery, expression or activity of rna interference agents
GB0920304D0 (en) * 2009-11-20 2010-01-06 Medical Res Council Novel liposome nanoparticles for tumour magnetic resonance imaging
NZ601109A (en) * 2009-12-10 2014-06-27 Merck Patent Gmbh Pharmaceutical composition comprising oligopeptides, preferably cilengitide
BR112012032153A2 (pt) 2010-06-17 2017-08-08 Yeda Res And Development Company Ltd método para a lubrificação de uma ou mais superfícies não biológicas, método para a lubrificação de uma ou mais superfícies de um tecido biológico em um indivíduo mamífero, uso de lipossomas na fase em gel e lipossoma misto
US9150655B2 (en) 2010-09-03 2015-10-06 Academia Sinica Anti-C-met antibody and methods of use thereof
EP2618821A4 (de) 2010-09-24 2014-08-13 Brigham & Womens Hospital Nanostrukturierte gele zur kontrollierten freisetzung verkapselter mittel
CN102078624B (zh) * 2010-12-23 2012-07-25 华东理工大学 一种高效载钆脂质体制剂及其制备方法
CA2827643C (en) 2011-02-18 2019-05-07 Kythera Biopharmaceuticals, Inc. Treatment of submental fat
US8653058B2 (en) 2011-04-05 2014-02-18 Kythera Biopharmaceuticals, Inc. Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits
WO2012167870A1 (en) * 2011-06-09 2012-12-13 Merck Patent Gmbh Treatment of cancers and metastases with suspensions of cilengitide in carrier
US9650407B2 (en) 2011-11-02 2017-05-16 The Regents Of The University Of California Reprogramming of cellular adhesion
TWI568453B (zh) * 2011-11-22 2017-02-01 原創生醫股份有限公司 具有螯合型複合微胞之藥物載體及其應用
KR101628586B1 (ko) * 2012-08-28 2016-06-08 (주)오리지날 바이오메디칼스 킬레이트 복합 교질입자로 구성된 의약 조성물의 제어방출방법
US8728454B1 (en) 2012-10-30 2014-05-20 The Clorox Company Cationic micelles with anionic polymeric counterions compositions thereof
US8765114B2 (en) 2012-10-30 2014-07-01 The Clorox Company Anionic micelles with cationic polymeric counterions methods thereof
US8883706B2 (en) 2012-10-30 2014-11-11 The Clorox Company Anionic micelles with cationic polymeric counterions systems thereof
CA2888961A1 (en) * 2012-10-30 2014-05-08 The Clorox Company Cationic micelles with anionic polymeric counterions compositions, methods and systems thereof
US8728530B1 (en) 2012-10-30 2014-05-20 The Clorox Company Anionic micelles with cationic polymeric counterions compositions thereof
US8883705B2 (en) 2012-10-30 2014-11-11 The Clorox Company Cationic micelles with anionic polymeric counterions systems thereof
CN102973508A (zh) * 2012-10-31 2013-03-20 河南牧翔动物药业有限公司 一种复方黄芪多糖脂质体长效注射液及其制备方法
WO2017062818A1 (en) 2015-10-08 2017-04-13 The Brigham And Women's Hospital, Inc. Stabilized assembled nanostructures for delivery of encapsulated agents
RU2718065C2 (ru) 2016-02-15 2020-03-30 Кемин Индастриз, Инк. Положительно заряженные липосомы в качестве липофильных молекул-носителей
WO2017193139A1 (en) 2016-05-06 2017-11-09 The Brigham And Women's Hospital, Inc. Binary self assembled gels for controlled delivery of encapsulated agents to cartilage
EP3452014A1 (de) * 2016-05-06 2019-03-13 The Brigham and Women's Hospital, Inc. Selbstangeordnetes gel zur kontrollierten abgabe von thermolabilen wirkstoffen
US11020410B2 (en) 2017-02-03 2021-06-01 The Brigham And Women's Hospital, Inc. Self-assembled gels formed with anti-retroviral drugs, prodrugs thereof, and pharmaceutical uses thereof
EP3361276A1 (de) * 2017-02-14 2018-08-15 Koninklijke Philips N.V. Brückenelement für ein magnetresonanzuntersuchungssystem
WO2018208822A1 (en) 2017-05-08 2018-11-15 Alivio Therapeutics, Inc. Formulation of nanostructured gels for increased agent loading and adhesion
EA031124B1 (ru) * 2017-05-15 2018-11-30 Деркач, Олег Вадимович Контрастное средство на основе аморфных или аморфно-кристаллических наночастиц оксидов или гидроксидов марганца для мрт исследований мозга
SI3672653T1 (sl) 2017-08-22 2023-08-31 Moebius Medical Ltd. Liposomska formulacija za mazanje sklepov
CN113038930A (zh) * 2018-06-27 2021-06-25 呼吸治疗公司 冻干形式的药物组合物
CN111450266A (zh) * 2020-03-30 2020-07-28 中国科学院大学宁波华美医院 靶向革兰氏阳性细菌的磁共振成像造影剂、制备和应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5387410A (en) * 1983-03-18 1995-02-07 Mallinckrodt, Inc. Method for enhancing magnetic resonance with compositions containing paramagnetic elements carried by liposomes
US4920016A (en) * 1986-12-24 1990-04-24 Linear Technology, Inc. Liposomes with enhanced circulation time
JPH0720857B2 (ja) * 1988-08-11 1995-03-08 テルモ株式会社 リポソームおよびその製法
IS1685B (is) 1990-12-11 1998-02-24 Bracco International B.V. Aðferð við að búa til fitukúlur (liposomes) sem eru gæddar auknum hæfileika til að draga í sig og halda í sér aðskotaefnum
US5534241A (en) * 1993-07-23 1996-07-09 Torchilin; Vladimir P. Amphipathic polychelating compounds and methods of use
US6217849B1 (en) * 1993-09-29 2001-04-17 Bracco Research S.A. Liposome suspensions as blood pool imaging contrast agents
US5716673A (en) * 1994-11-07 1998-02-10 Macronix Internationalco., Ltd. Spin-on-glass process with controlled environment
US6139819A (en) * 1995-06-07 2000-10-31 Imarx Pharmaceutical Corp. Targeted contrast agents for diagnostic and therapeutic use
US5833948A (en) 1995-06-15 1998-11-10 Bracco Research S.A. Blood-pool imaging composition comprising micelles containing a lipophilic chelating agent and a non-ionic surfactant
WO1998018501A2 (en) 1996-10-28 1998-05-07 Marsden, John, Christopher Improvements in or relating to diagnostic/therapeutic agents
US5827533A (en) * 1997-02-06 1998-10-27 Duke University Liposomes containing active agents aggregated with lipid surfactants
GB9809084D0 (en) 1998-04-28 1998-06-24 Nycomed Imaging As Improvements in or relating to diagnostic/therapeutic agents
WO2000009170A1 (en) * 1998-08-10 2000-02-24 Bracco Research S.A. Combination of a positive mri contrast agent with a negative mri contrast agent
US6342598B1 (en) * 1998-11-26 2002-01-29 Bracco International B.V. Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents
US6328988B1 (en) * 1999-04-23 2001-12-11 Rutgers, The State University Of New Jersey Hyperbranched polymeric micelles for encapsulation and delivery of hydrophobic molecules
CA2432474C (en) 2000-12-23 2012-06-26 Dyax Corp. Fibrin binding polypeptides useful inter alia in medical imaging processes
SI1482987T1 (sl) 2002-03-01 2014-12-31 Bracco Suisse Sa Večvalentni konstrukti za terapevtske in diagnostične aplikacije
ES2398393T3 (es) 2002-03-01 2013-03-15 Dyax Corp. Péptidos de unión a KDR y a VEGF/KDR y su uso en diagnóstico y terapia

Also Published As

Publication number Publication date
EP1750671B1 (de) 2008-10-15
JP2008501667A (ja) 2008-01-24
EP1750671A1 (de) 2007-02-14
JP4773430B2 (ja) 2011-09-14
WO2005117832A1 (en) 2005-12-15
US20070196284A1 (en) 2007-08-23
CN1960707A (zh) 2007-05-09
DE602005010424D1 (de) 2008-11-27
CN1960707B (zh) 2012-11-14
ES2313352T3 (es) 2009-03-01
US7749485B2 (en) 2010-07-06

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