ATE411006T1 - Liposomale anordnung für die therapeutische und/oder diagnostische anwendung - Google Patents
Liposomale anordnung für die therapeutische und/oder diagnostische anwendungInfo
- Publication number
- ATE411006T1 ATE411006T1 AT05749164T AT05749164T ATE411006T1 AT E411006 T1 ATE411006 T1 AT E411006T1 AT 05749164 T AT05749164 T AT 05749164T AT 05749164 T AT05749164 T AT 05749164T AT E411006 T1 ATE411006 T1 AT E411006T1
- Authority
- AT
- Austria
- Prior art keywords
- liposome
- therapeutic
- micellar
- diagnostic use
- active compound
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 239000002502 liposome Substances 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 230000009881 electrostatic interaction Effects 0.000 abstract 1
- 239000000693 micelle Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0091—Purification or manufacturing processes for gene therapy compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1806—Suspensions, emulsions, colloids, dispersions
- A61K49/1812—Suspensions, emulsions, colloids, dispersions liposomes, polymersomes, e.g. immunoliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
- Y10S977/907—Liposome
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Dispersion Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Manufacturing & Machinery (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04013141 | 2004-06-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE411006T1 true ATE411006T1 (de) | 2008-10-15 |
Family
ID=34925239
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05749164T ATE411006T1 (de) | 2004-06-03 | 2005-05-31 | Liposomale anordnung für die therapeutische und/oder diagnostische anwendung |
Country Status (8)
Country | Link |
---|---|
US (1) | US7749485B2 (de) |
EP (1) | EP1750671B1 (de) |
JP (1) | JP4773430B2 (de) |
CN (1) | CN1960707B (de) |
AT (1) | ATE411006T1 (de) |
DE (1) | DE602005010424D1 (de) |
ES (1) | ES2313352T3 (de) |
WO (1) | WO2005117832A1 (de) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060127468A1 (en) | 2004-05-19 | 2006-06-15 | Kolodney Michael S | Methods and related compositions for reduction of fat and skin tightening |
ATE521355T1 (de) | 2004-05-19 | 2011-09-15 | Los Angeles Biomed Res Inst | Verwendung eines detergens zur nicht- chirurgischen entfernung von fett |
US7754230B2 (en) | 2004-05-19 | 2010-07-13 | The Regents Of The University Of California | Methods and related compositions for reduction of fat |
US20070154403A1 (en) * | 2006-01-05 | 2007-07-05 | Thomas Skold | Oral, Pulmonary and Transmucosal Delivery Composition |
US8114150B2 (en) * | 2006-06-14 | 2012-02-14 | Advanced Cardiovascular Systems, Inc. | RGD peptide attached to bioabsorbable stents |
CA2664944C (en) * | 2006-09-28 | 2016-06-14 | Hadasit Medical Research Services & Development Limited | Use of glycerophospholipids for joint lubrication |
WO2009091531A2 (en) * | 2008-01-16 | 2009-07-23 | The General Hospital Corporation | Uniform-sized, multi-drug carrying and photosensitive liposomes for advance drug delivery |
EP2147684A1 (de) | 2008-07-22 | 2010-01-27 | Bracco Imaging S.p.A | Selektiv gegen Metallproteasen wirkende Diagnosemittel |
US20110229565A1 (en) | 2008-09-17 | 2011-09-22 | Karp Jeffrey M | Drug Delivery Composition Comprising a Self-Assembled Gelator |
AU2009301141B2 (en) | 2008-10-07 | 2015-08-27 | Bracco Suisse S.A. | Targeting construct comprising anti-polymer antibody and liposomes or microvesicles binding to the same |
US8101593B2 (en) | 2009-03-03 | 2012-01-24 | Kythera Biopharmaceuticals, Inc. | Formulations of deoxycholic acid and salts thereof |
BRPI1012246A2 (pt) * | 2009-03-25 | 2016-03-29 | Novartis Ag | composição farmacêutica contendo um fármaco e sirna |
JP5491067B2 (ja) * | 2009-05-08 | 2014-05-14 | 一雄 丸山 | リポソーム、リポソームの製造方法、及び医薬組成物 |
WO2011046934A1 (en) * | 2009-10-12 | 2011-04-21 | Au Jessie L-S | Methods and compositions for improved delivery, expression or activity of rna interference agents |
GB0920304D0 (en) * | 2009-11-20 | 2010-01-06 | Medical Res Council | Novel liposome nanoparticles for tumour magnetic resonance imaging |
NZ601109A (en) * | 2009-12-10 | 2014-06-27 | Merck Patent Gmbh | Pharmaceutical composition comprising oligopeptides, preferably cilengitide |
BR112012032153A2 (pt) | 2010-06-17 | 2017-08-08 | Yeda Res And Development Company Ltd | método para a lubrificação de uma ou mais superfícies não biológicas, método para a lubrificação de uma ou mais superfícies de um tecido biológico em um indivíduo mamífero, uso de lipossomas na fase em gel e lipossoma misto |
US9150655B2 (en) | 2010-09-03 | 2015-10-06 | Academia Sinica | Anti-C-met antibody and methods of use thereof |
EP2618821A4 (de) | 2010-09-24 | 2014-08-13 | Brigham & Womens Hospital | Nanostrukturierte gele zur kontrollierten freisetzung verkapselter mittel |
CN102078624B (zh) * | 2010-12-23 | 2012-07-25 | 华东理工大学 | 一种高效载钆脂质体制剂及其制备方法 |
CA2827643C (en) | 2011-02-18 | 2019-05-07 | Kythera Biopharmaceuticals, Inc. | Treatment of submental fat |
US8653058B2 (en) | 2011-04-05 | 2014-02-18 | Kythera Biopharmaceuticals, Inc. | Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits |
WO2012167870A1 (en) * | 2011-06-09 | 2012-12-13 | Merck Patent Gmbh | Treatment of cancers and metastases with suspensions of cilengitide in carrier |
US9650407B2 (en) | 2011-11-02 | 2017-05-16 | The Regents Of The University Of California | Reprogramming of cellular adhesion |
TWI568453B (zh) * | 2011-11-22 | 2017-02-01 | 原創生醫股份有限公司 | 具有螯合型複合微胞之藥物載體及其應用 |
KR101628586B1 (ko) * | 2012-08-28 | 2016-06-08 | (주)오리지날 바이오메디칼스 | 킬레이트 복합 교질입자로 구성된 의약 조성물의 제어방출방법 |
US8728454B1 (en) | 2012-10-30 | 2014-05-20 | The Clorox Company | Cationic micelles with anionic polymeric counterions compositions thereof |
US8765114B2 (en) | 2012-10-30 | 2014-07-01 | The Clorox Company | Anionic micelles with cationic polymeric counterions methods thereof |
US8883706B2 (en) | 2012-10-30 | 2014-11-11 | The Clorox Company | Anionic micelles with cationic polymeric counterions systems thereof |
CA2888961A1 (en) * | 2012-10-30 | 2014-05-08 | The Clorox Company | Cationic micelles with anionic polymeric counterions compositions, methods and systems thereof |
US8728530B1 (en) | 2012-10-30 | 2014-05-20 | The Clorox Company | Anionic micelles with cationic polymeric counterions compositions thereof |
US8883705B2 (en) | 2012-10-30 | 2014-11-11 | The Clorox Company | Cationic micelles with anionic polymeric counterions systems thereof |
CN102973508A (zh) * | 2012-10-31 | 2013-03-20 | 河南牧翔动物药业有限公司 | 一种复方黄芪多糖脂质体长效注射液及其制备方法 |
WO2017062818A1 (en) | 2015-10-08 | 2017-04-13 | The Brigham And Women's Hospital, Inc. | Stabilized assembled nanostructures for delivery of encapsulated agents |
RU2718065C2 (ru) | 2016-02-15 | 2020-03-30 | Кемин Индастриз, Инк. | Положительно заряженные липосомы в качестве липофильных молекул-носителей |
WO2017193139A1 (en) | 2016-05-06 | 2017-11-09 | The Brigham And Women's Hospital, Inc. | Binary self assembled gels for controlled delivery of encapsulated agents to cartilage |
EP3452014A1 (de) * | 2016-05-06 | 2019-03-13 | The Brigham and Women's Hospital, Inc. | Selbstangeordnetes gel zur kontrollierten abgabe von thermolabilen wirkstoffen |
US11020410B2 (en) | 2017-02-03 | 2021-06-01 | The Brigham And Women's Hospital, Inc. | Self-assembled gels formed with anti-retroviral drugs, prodrugs thereof, and pharmaceutical uses thereof |
EP3361276A1 (de) * | 2017-02-14 | 2018-08-15 | Koninklijke Philips N.V. | Brückenelement für ein magnetresonanzuntersuchungssystem |
WO2018208822A1 (en) | 2017-05-08 | 2018-11-15 | Alivio Therapeutics, Inc. | Formulation of nanostructured gels for increased agent loading and adhesion |
EA031124B1 (ru) * | 2017-05-15 | 2018-11-30 | Деркач, Олег Вадимович | Контрастное средство на основе аморфных или аморфно-кристаллических наночастиц оксидов или гидроксидов марганца для мрт исследований мозга |
SI3672653T1 (sl) | 2017-08-22 | 2023-08-31 | Moebius Medical Ltd. | Liposomska formulacija za mazanje sklepov |
CN113038930A (zh) * | 2018-06-27 | 2021-06-25 | 呼吸治疗公司 | 冻干形式的药物组合物 |
CN111450266A (zh) * | 2020-03-30 | 2020-07-28 | 中国科学院大学宁波华美医院 | 靶向革兰氏阳性细菌的磁共振成像造影剂、制备和应用 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
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US5387410A (en) * | 1983-03-18 | 1995-02-07 | Mallinckrodt, Inc. | Method for enhancing magnetic resonance with compositions containing paramagnetic elements carried by liposomes |
US4920016A (en) * | 1986-12-24 | 1990-04-24 | Linear Technology, Inc. | Liposomes with enhanced circulation time |
JPH0720857B2 (ja) * | 1988-08-11 | 1995-03-08 | テルモ株式会社 | リポソームおよびその製法 |
IS1685B (is) | 1990-12-11 | 1998-02-24 | Bracco International B.V. | Aðferð við að búa til fitukúlur (liposomes) sem eru gæddar auknum hæfileika til að draga í sig og halda í sér aðskotaefnum |
US5534241A (en) * | 1993-07-23 | 1996-07-09 | Torchilin; Vladimir P. | Amphipathic polychelating compounds and methods of use |
US6217849B1 (en) * | 1993-09-29 | 2001-04-17 | Bracco Research S.A. | Liposome suspensions as blood pool imaging contrast agents |
US5716673A (en) * | 1994-11-07 | 1998-02-10 | Macronix Internationalco., Ltd. | Spin-on-glass process with controlled environment |
US6139819A (en) * | 1995-06-07 | 2000-10-31 | Imarx Pharmaceutical Corp. | Targeted contrast agents for diagnostic and therapeutic use |
US5833948A (en) | 1995-06-15 | 1998-11-10 | Bracco Research S.A. | Blood-pool imaging composition comprising micelles containing a lipophilic chelating agent and a non-ionic surfactant |
WO1998018501A2 (en) | 1996-10-28 | 1998-05-07 | Marsden, John, Christopher | Improvements in or relating to diagnostic/therapeutic agents |
US5827533A (en) * | 1997-02-06 | 1998-10-27 | Duke University | Liposomes containing active agents aggregated with lipid surfactants |
GB9809084D0 (en) | 1998-04-28 | 1998-06-24 | Nycomed Imaging As | Improvements in or relating to diagnostic/therapeutic agents |
WO2000009170A1 (en) * | 1998-08-10 | 2000-02-24 | Bracco Research S.A. | Combination of a positive mri contrast agent with a negative mri contrast agent |
US6342598B1 (en) * | 1998-11-26 | 2002-01-29 | Bracco International B.V. | Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents |
US6328988B1 (en) * | 1999-04-23 | 2001-12-11 | Rutgers, The State University Of New Jersey | Hyperbranched polymeric micelles for encapsulation and delivery of hydrophobic molecules |
CA2432474C (en) | 2000-12-23 | 2012-06-26 | Dyax Corp. | Fibrin binding polypeptides useful inter alia in medical imaging processes |
SI1482987T1 (sl) | 2002-03-01 | 2014-12-31 | Bracco Suisse Sa | Večvalentni konstrukti za terapevtske in diagnostične aplikacije |
ES2398393T3 (es) | 2002-03-01 | 2013-03-15 | Dyax Corp. | Péptidos de unión a KDR y a VEGF/KDR y su uso en diagnóstico y terapia |
-
2005
- 2005-05-31 CN CN200580017753.2A patent/CN1960707B/zh not_active Expired - Fee Related
- 2005-05-31 US US11/596,447 patent/US7749485B2/en not_active Expired - Fee Related
- 2005-05-31 JP JP2007513959A patent/JP4773430B2/ja not_active Expired - Fee Related
- 2005-05-31 WO PCT/EP2005/052482 patent/WO2005117832A1/en not_active Application Discontinuation
- 2005-05-31 AT AT05749164T patent/ATE411006T1/de not_active IP Right Cessation
- 2005-05-31 EP EP05749164A patent/EP1750671B1/de not_active Not-in-force
- 2005-05-31 ES ES05749164T patent/ES2313352T3/es active Active
- 2005-05-31 DE DE602005010424T patent/DE602005010424D1/de active Active
Also Published As
Publication number | Publication date |
---|---|
EP1750671B1 (de) | 2008-10-15 |
JP2008501667A (ja) | 2008-01-24 |
EP1750671A1 (de) | 2007-02-14 |
JP4773430B2 (ja) | 2011-09-14 |
WO2005117832A1 (en) | 2005-12-15 |
US20070196284A1 (en) | 2007-08-23 |
CN1960707A (zh) | 2007-05-09 |
DE602005010424D1 (de) | 2008-11-27 |
CN1960707B (zh) | 2012-11-14 |
ES2313352T3 (es) | 2009-03-01 |
US7749485B2 (en) | 2010-07-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |