ATE404664T1 - Aldehyddehyrdrogenase-gen - Google Patents

Aldehyddehyrdrogenase-gen

Info

Publication number
ATE404664T1
ATE404664T1 AT03798171T AT03798171T ATE404664T1 AT E404664 T1 ATE404664 T1 AT E404664T1 AT 03798171 T AT03798171 T AT 03798171T AT 03798171 T AT03798171 T AT 03798171T AT E404664 T1 ATE404664 T1 AT E404664T1
Authority
AT
Austria
Prior art keywords
aldehyde dehydrogenase
recombinant
dna
expression vector
gene
Prior art date
Application number
AT03798171T
Other languages
German (de)
English (en)
Inventor
Tatsuo Hoshino
Taro Miyazaki
Teruhide Sugisawa
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Application granted granted Critical
Publication of ATE404664T1 publication Critical patent/ATE404664T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58Aldonic, ketoaldonic or saccharic acids
    • C12P7/602-Ketogulonic acid

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT03798171T 2002-09-27 2003-09-22 Aldehyddehyrdrogenase-gen ATE404664T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02021650 2002-09-27

Publications (1)

Publication Number Publication Date
ATE404664T1 true ATE404664T1 (de) 2008-08-15

Family

ID=32039112

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03798171T ATE404664T1 (de) 2002-09-27 2003-09-22 Aldehyddehyrdrogenase-gen

Country Status (9)

Country Link
US (1) US7135315B2 (https=)
EP (1) EP1543114B1 (https=)
JP (1) JP4528624B2 (https=)
KR (1) KR101070110B1 (https=)
CN (2) CN101693896B (https=)
AT (1) ATE404664T1 (https=)
AU (1) AU2003299104A1 (https=)
DE (1) DE60322921D1 (https=)
WO (1) WO2004029235A2 (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005017172A1 (en) * 2003-08-14 2005-02-24 Dsm Ip Assets B.V. Microbial production of l-ascorbic acid
US9279138B2 (en) * 2005-02-11 2016-03-08 Dsm Assets B.V. Vitamin C production in a microorganism, gluconobacter
WO2006084725A1 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Novel gene sts 16
WO2006084647A1 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Gene vcs 01
WO2006084720A2 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Hpr kinase from gluconobacter oxydan
CN101316929A (zh) 2005-09-08 2008-12-03 帝斯曼知识产权资产管理有限公司 新颖的基因sms 37
EP1931785A2 (en) 2005-09-09 2008-06-18 DSMIP Assets B.V. Novel gene gms 01
LT2821494T (lt) 2007-03-16 2017-04-25 Genomatica, Inc. 1,4-butandiolio ir jo pirmtakų biosintezės būdai ir kompozicijos
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
US7858350B2 (en) 2008-09-10 2010-12-28 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol
SI3199511T1 (sl) 2009-06-04 2020-07-31 Genomatica, Inc. Proces separacije komponent fermentacijske brozge
WO2010141920A2 (en) 2009-06-04 2010-12-09 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol and related methods
CN101649323B (zh) * 2009-06-16 2011-06-22 武汉工程大学 按毕赤酵母偏爱密码子设计人乙醛脱氢酶2序列的方法
US8377666B2 (en) 2009-10-13 2013-02-19 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-coa, putrescine and related compounds, and methods related thereto
US8530210B2 (en) 2009-11-25 2013-09-10 Genomatica, Inc. Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone
US8637286B2 (en) 2010-02-23 2014-01-28 Genomatica, Inc. Methods for increasing product yields
US8048661B2 (en) 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
CN102492762A (zh) * 2011-12-09 2012-06-13 天津大学 含有编码山梨酮脱氢酶基因载体的氧化葡糖杆菌的用途
WO2013184602A2 (en) 2012-06-04 2013-12-12 Genomatica, Inc. Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds
EP3856896A1 (en) * 2018-09-26 2021-08-04 Genomatica, Inc. Aldehyde dehydrogenase variants and methods of using same
CN111321153B (zh) * 2020-04-26 2021-08-17 广西大学 一种来源于玉米的黑暗响应gd2基因及其应用
KR102460589B1 (ko) 2021-02-17 2022-10-28 주식회사 피코엔텍 글루타치온과 알데히드탈수소효소를 함유하는 숙취해소제
CN115948430B (zh) * 2022-05-26 2024-06-14 南京农业大学 梨醛脱氢酶PusALDH1及其编码基因和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0373181B1 (en) * 1988-01-14 1995-11-08 F. Hoffmann-La Roche Ag Novel coenzyme independent l-sorbosone dehydrogenase
US5437989A (en) * 1992-12-30 1995-08-01 Hoffmann-La Roche Inc. Alcohol/aldehyde dehydrogenase from Gluconobacter oxydans DSM 4025 FERM BP-3812
US5776742A (en) 1996-02-19 1998-07-07 Roche Vitamins Inc. Aldehyde dehydrogenase enzyme
DE69821326T2 (de) * 1997-12-01 2004-11-18 Dsm Ip Assets B.V. Aldehyd-Dehydrogenase
CN1351665A (zh) * 1999-03-17 2002-05-29 藤泽药品工业株式会社 山梨糖醇脱氢酶、其编码基因及它们的用途
JP2002125689A (ja) 2000-10-25 2002-05-08 Koji Hayade 融合蛋白質
EP1332216B1 (en) 2000-10-27 2011-08-17 Roche Diagnostics GmbH Variants of soluble pyrroloquinoline quinone-dependent glucose dehydrogenase

Also Published As

Publication number Publication date
EP1543114B1 (en) 2008-08-13
CN1688689A (zh) 2005-10-26
KR20050052664A (ko) 2005-06-03
US20060127994A1 (en) 2006-06-15
US7135315B2 (en) 2006-11-14
JP2006500052A (ja) 2006-01-05
CN101693896A (zh) 2010-04-14
JP4528624B2 (ja) 2010-08-18
EP1543114A2 (en) 2005-06-22
AU2003299104A8 (en) 2004-04-19
AU2003299104A1 (en) 2004-04-19
CN100558886C (zh) 2009-11-11
WO2004029235A3 (en) 2004-07-08
CN101693896B (zh) 2012-07-11
WO2004029235A2 (en) 2004-04-08
DE60322921D1 (de) 2008-09-25
KR101070110B1 (ko) 2011-10-05

Similar Documents

Publication Publication Date Title
DE60322921D1 (de) Aldehyddehyrdrogenase-gen
Pappenberger et al. Industrial production of L-ascorbic acid (vitamin C) and D-isoascorbic acid
Bremus et al. The use of microorganisms in L-ascorbic acid production
Yang et al. Industrial fermentation of vitamin C
BRPI0401812A (pt) Métodos para produzir um dicarboxilato de cadaverina, e, náilon
BR0012712B1 (pt) métodos de produção de l-aminoácidos aumentando-se o nadph celular.
WO2005017159A3 (en) Microbial production of l-ascorbic acid
DK1309698T3 (da) Cytochrom P450-enzym forbundet med syntesen af delta-12-epoxy-grupper i plantefedtsyrer
ATE326523T1 (de) Verfahren zur fermentativen herstellung von l- methionin
Shi et al. Identification of a novel promoter gHp0169 for gene expression in Gluconobacter oxydans
EP1995314A4 (en) PROCESS FOR THE PRODUCTION OF ERYTHRO OR THREO-2-AMINO-3-HYDROXYPROPIONIC ACID ESTERS, NOVEL CARBONYL REDUCTASE, REDUCTASE, VECTOR, TRANSFORMANT AND PROCEDURE FOR THE PRODUCTION OF OPTICALLY ACTIVE ALCOHOL USED THEREOF
ATE248916T1 (de) Gene, die verzweigte-alpha-ketosäure- dehydrogenasekomplexe von streptomyces avermitius kodieren
ATE318907T1 (de) Erhöhte herstellung von 2-keto-l-gulonsäure
WO2001072974A3 (en) L-galactose dehydrogenase from arabidopsis thaliana, and uses thereof
Ben Azoun et al. Investigating the effect of carbon source on rabies virus glycoprotein production in Pichia pastoris by a transcriptomic approach
EA200701694A1 (ru) Ферментативное получение витамина с
AR034550A1 (es) Un polinucleotido, un vector, una celula hospedadora, un polipeptido, ml-236b, un metodo para su produccion, un metodo para fabricar pravastatina, un anticuerpo reactivo.
ATE220104T1 (de) Expressionssystem zur produktion von proteinen
EA200700287A1 (ru) Улучшенные ферменты
ATE417117T1 (de) Verfahren zur herstellung von 2-keto-l-gulonsäure
Running et al. The biotechnology of ascorbic acid manufacture
ATE323172T1 (de) Herstellung von l-ascorbinsäure und d- erythorbinsäure
WO2002061106A3 (de) Verfahren zur fermentativen herstellung von cystein, cystin und glutathion
Niwa et al. Method for producing 2-keto-L-gulonic acid
AR122916A1 (es) Glutamato deshidrogenasa modificada y uso de la misma

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties