DE60322921D1 - Aldehyddehyrdrogenase-gen - Google Patents

Aldehyddehyrdrogenase-gen

Info

Publication number
DE60322921D1
DE60322921D1 DE60322921T DE60322921T DE60322921D1 DE 60322921 D1 DE60322921 D1 DE 60322921D1 DE 60322921 T DE60322921 T DE 60322921T DE 60322921 T DE60322921 T DE 60322921T DE 60322921 D1 DE60322921 D1 DE 60322921D1
Authority
DE
Germany
Prior art keywords
aldehyde dehydrogenase
recombinant
dna
expression vector
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60322921T
Other languages
English (en)
Inventor
Tatsuo Hoshino
Taro Miyazaki
Teruhide Sugisawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Application granted granted Critical
Publication of DE60322921D1 publication Critical patent/DE60322921D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58—Aldonic, ketoaldonic or saccharic acids
    • C12P7/60—2-Ketogulonic acid
DE60322921T 2002-09-27 2003-09-22 Aldehyddehyrdrogenase-gen Expired - Lifetime DE60322921D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02021650 2002-09-27
PCT/EP2003/010498 WO2004029235A2 (en) 2002-09-27 2003-09-22 Aldehyde dehydrogenase gene

Publications (1)

Publication Number Publication Date
DE60322921D1 true DE60322921D1 (de) 2008-09-25

Family

ID=32039112

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60322921T Expired - Lifetime DE60322921D1 (de) 2002-09-27 2003-09-22 Aldehyddehyrdrogenase-gen

Country Status (9)

Country Link
US (1) US7135315B2 (de)
EP (1) EP1543114B1 (de)
JP (1) JP4528624B2 (de)
KR (1) KR101070110B1 (de)
CN (2) CN101693896B (de)
AT (1) ATE404664T1 (de)
AU (1) AU2003299104A1 (de)
DE (1) DE60322921D1 (de)
WO (1) WO2004029235A2 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005017172A1 (en) * 2003-08-14 2005-02-24 Dsm Ip Assets B.V. Microbial production of l-ascorbic acid
WO2006084708A1 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Gene sms 05
WO2006084647A1 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Gene vcs 01
WO2006084720A2 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Hpr kinase from gluconobacter oxydan
WO2006084725A1 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Novel gene sts 16
WO2007028602A1 (en) 2005-09-08 2007-03-15 Dsm Ip Assets B.V. Novel gene sms 37
CN101341250B (zh) * 2005-09-09 2013-03-20 帝斯曼知识产权资产管理有限公司 使用具有被打断的葡糖脱氢酶基因(gms 01)的微生物来生产生物质的工艺
BRPI0808988A2 (pt) 2007-03-16 2011-11-08 Genomatica Inc micro-organismos e métodos para a produção de 1,4-butanodiol (1,4-bdo)
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
CA2735883C (en) 2008-09-10 2020-05-05 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol
US8129169B2 (en) 2009-06-04 2012-03-06 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol and related methods
CN102459138A (zh) 2009-06-04 2012-05-16 基因组股份公司 分离发酵液成分的方法
CN101649323B (zh) * 2009-06-16 2011-06-22 武汉工程大学 按毕赤酵母偏爱密码子设计人乙醛脱氢酶2序列的方法
CN105441374A (zh) 2009-10-13 2016-03-30 基因组股份公司 生产1,4-丁二醇、4-羟基丁醛、4-羟基丁酰-coa、腐胺和相关化合物的微生物及其相关方法
US8530210B2 (en) 2009-11-25 2013-09-10 Genomatica, Inc. Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone
US8445244B2 (en) 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
US8048661B2 (en) 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
CN102492762A (zh) * 2011-12-09 2012-06-13 天津大学 含有编码山梨酮脱氢酶基因载体的氧化葡糖杆菌的用途
EP2855687B1 (de) 2012-06-04 2020-04-22 Genomatica, Inc. Mikroorganismen und verfahren zur herstellung von 4-hydroxybutyrat, 1,4-butandiol und verwandten verbindungen
CN113179645A (zh) * 2018-09-26 2021-07-27 基因组股份公司 醛脱氢酶变体及其使用方法
CN111321153B (zh) * 2020-04-26 2021-08-17 广西大学 一种来源于玉米的黑暗响应gd2基因及其应用
KR102460589B1 (ko) 2021-02-17 2022-10-28 주식회사 피코엔텍 글루타치온과 알데히드탈수소효소를 함유하는 숙취해소제

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68924761T2 (de) 1988-01-14 1996-04-04 Hoffmann La Roche Neue coenzym unabhängige l-sorbosone dehydrogenase.
US5437989A (en) 1992-12-30 1995-08-01 Hoffmann-La Roche Inc. Alcohol/aldehyde dehydrogenase from Gluconobacter oxydans DSM 4025 FERM BP-3812
US5776742A (en) * 1996-02-19 1998-07-07 Roche Vitamins Inc. Aldehyde dehydrogenase enzyme
DE69821326T2 (de) * 1997-12-01 2004-11-18 Dsm Ip Assets B.V. Aldehyd-Dehydrogenase
WO2000055329A1 (fr) * 1999-03-17 2000-09-21 Fujisawa Pharmaceutical Co., Ltd. Sorbitol deshydrogenase, gene codant pour celle-ci et leur utilisation
JP2002125689A (ja) * 2000-10-25 2002-05-08 Koji Hayade 融合蛋白質
KR100519902B1 (ko) * 2000-10-27 2005-10-10 에프. 호프만-라 로슈 아게 가용성 피롤로퀴놀린 퀴논 의존성 글루코오스 디히드로게나아제의 변이체

Also Published As

Publication number Publication date
CN1688689A (zh) 2005-10-26
EP1543114B1 (de) 2008-08-13
CN101693896A (zh) 2010-04-14
CN101693896B (zh) 2012-07-11
JP4528624B2 (ja) 2010-08-18
AU2003299104A1 (en) 2004-04-19
US20060127994A1 (en) 2006-06-15
WO2004029235A3 (en) 2004-07-08
US7135315B2 (en) 2006-11-14
CN100558886C (zh) 2009-11-11
WO2004029235A2 (en) 2004-04-08
AU2003299104A8 (en) 2004-04-19
JP2006500052A (ja) 2006-01-05
ATE404664T1 (de) 2008-08-15
EP1543114A2 (de) 2005-06-22
KR20050052664A (ko) 2005-06-03
KR101070110B1 (ko) 2011-10-05

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