ATE403672T1 - Oral aktive fraktion der momordica charantia, ihre aktiven peptide und ihre verwendung bei der behandlung des diabetes - Google Patents

Oral aktive fraktion der momordica charantia, ihre aktiven peptide und ihre verwendung bei der behandlung des diabetes

Info

Publication number
ATE403672T1
ATE403672T1 AT98914405T AT98914405T ATE403672T1 AT E403672 T1 ATE403672 T1 AT E403672T1 AT 98914405 T AT98914405 T AT 98914405T AT 98914405 T AT98914405 T AT 98914405T AT E403672 T1 ATE403672 T1 AT E403672T1
Authority
AT
Austria
Prior art keywords
active
treatment
diabetes
methods
peptides
Prior art date
Application number
AT98914405T
Other languages
German (de)
English (en)
Inventor
Bishwajit Nag
Satyanarayana Medicherla
Somesh Sharma
Original Assignee
Theracos Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theracos Inc filed Critical Theracos Inc
Application granted granted Critical
Publication of ATE403672T1 publication Critical patent/ATE403672T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A61K38/011—Hydrolysed proteins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT98914405T 1997-04-01 1998-04-01 Oral aktive fraktion der momordica charantia, ihre aktiven peptide und ihre verwendung bei der behandlung des diabetes ATE403672T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83103997A 1997-04-01 1997-04-01
US85085597A 1997-05-02 1997-05-02

Publications (1)

Publication Number Publication Date
ATE403672T1 true ATE403672T1 (de) 2008-08-15

Family

ID=27125412

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98914405T ATE403672T1 (de) 1997-04-01 1998-04-01 Oral aktive fraktion der momordica charantia, ihre aktiven peptide und ihre verwendung bei der behandlung des diabetes

Country Status (11)

Country Link
US (3) US6127338A (enExample)
EP (1) EP1005274B1 (enExample)
JP (1) JP4156038B2 (enExample)
KR (1) KR100509438B1 (enExample)
CN (1) CN1255044A (enExample)
AT (1) ATE403672T1 (enExample)
AU (1) AU749792B2 (enExample)
CA (1) CA2285452A1 (enExample)
DE (1) DE69839842D1 (enExample)
ES (1) ES2310006T3 (enExample)
WO (1) WO1998043484A1 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1171455B1 (en) * 1999-04-13 2008-11-19 Pushpa Khanna Polypeptide-k obtained from momordica charantia and a process for the extraction thereof
WO2005063156A1 (en) * 2003-12-22 2005-07-14 Shear/Kershman Laboratories, Inc. Oral peptide delivery system with improved bioavailability
EP1563842A1 (en) * 2004-02-03 2005-08-17 Novartis AG Simarouba amara and/or Momordica charantia extracts for the treatment of coccidiosis in poultry
US20070269898A1 (en) * 2004-09-15 2007-11-22 Yokohama City University Amino Acid Sequences Essential to Neuron Specific Gene Expression
WO2008120240A1 (en) * 2007-03-30 2008-10-09 Aparna Dixit Anti diabetic protein
US20100081860A1 (en) * 2008-04-24 2010-04-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational System and Method for Memory Modification
TWI342781B (en) * 2008-12-01 2011-06-01 Univ China Medical Blood sugar-modulating polypeptides
WO2011032360A1 (zh) * 2009-09-17 2011-03-24 中国药科大学 苦瓜mc-jj2多肽及其应用与微波促进固相合成方法
WO2011032359A1 (zh) * 2009-09-17 2011-03-24 中国药科大学 苦瓜mc-jj6多肽及其应用与微波促进固相合成方法
CN101691394B (zh) * 2009-09-17 2012-05-09 中国药科大学 微波促进固相合成苦瓜mc-jj6多肽类似物及其应用
CN101824075A (zh) * 2010-05-20 2010-09-08 中国药科大学 微波促进固相合成苦瓜mc-jj0101多肽类似物及其应用
CN101824076A (zh) * 2010-05-20 2010-09-08 中国药科大学 微波促进固相合成苦瓜mc-jj0105多肽类似物及其应用
CN101942010A (zh) * 2010-05-20 2011-01-12 中国药科大学 微波促进固相合成苦瓜mc-jj0106多肽类似物及其应用
CN101824074A (zh) * 2010-05-20 2010-09-08 中国药科大学 微波促进固相合成苦瓜mc-jj0107多肽类似物及其应用
CN101838309A (zh) * 2010-05-20 2010-09-22 中国药科大学 微波促进固相合成苦瓜mc-jj0102多肽类似物及其应用
CN101824073A (zh) * 2010-05-20 2010-09-08 中国药科大学 微波促进固相合成苦瓜mc-jj0103多肽类似物及其应用
CN101830969A (zh) * 2010-05-20 2010-09-15 中国药科大学 微波促进固相合成苦瓜降血糖mc-jj0104多肽类似物及其应用
CN101985644B (zh) * 2010-10-25 2013-06-12 邹远东 一种苦瓜多肽及其制备方法与应用
ES2621355T3 (es) 2011-01-28 2017-07-03 Piramal Enterprises Limited Procedimiento para la preparación de un extracto de Momordica Charantia
TWI588153B (zh) 2012-05-18 2017-06-21 中國醫藥大學 多胜肽、編碼該多胜肽之核酸分子、以及該多胜肽之應用
CN104650198B (zh) * 2015-02-09 2018-05-08 武汉华康臣生物科技有限公司 三叉黑顶藻中分离的能治疗糖尿病的活性肽及其用途
CN106729606A (zh) * 2017-01-03 2017-05-31 河北省农林科学院经济作物研究所 苦瓜降糖提取物复合剂及其制备方法
CN107412721B (zh) * 2017-09-15 2020-11-24 李玉保 一种降血糖苦瓜多肽复方胶囊及其制备方法
CN107412720A (zh) * 2017-09-15 2017-12-01 李玉保 一种治疗糖尿病的苦瓜多肽复方植物药及其制备方法
CN108707181B (zh) * 2018-06-14 2021-03-12 苏秀兰 一种抑制肿瘤细胞增殖的苦瓜多肽及其制备方法和应用
CN110755598A (zh) * 2019-10-25 2020-02-07 李玉保 活化胰岛素及治疗糖尿病的复合苦瓜肽口服药及制备方法
CN112675292B (zh) * 2021-01-11 2021-11-02 中食安泓(广东)健康产业有限公司 含有益生菌的制剂在治疗疾病中的应用
CN116813700B (zh) * 2022-11-08 2025-01-24 苏秀兰 一种苦瓜生物活性肽、制备方法及其应用
CN117700489B (zh) * 2023-12-19 2024-08-20 深圳泰华赛尔生物科技有限公司 脂肪干细胞在治疗糖尿病的药物中的应用
CN119320429B (zh) * 2024-10-15 2025-07-29 天津桂芝堂科技有限公司 包含乳铁蛋白的药物组合物及在降血脂中的应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154598B (nl) * 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3853914A (en) * 1971-01-11 1974-12-10 Syva Co Ligand determination of spin labeled compounds by receptor displacement
US3817837A (en) * 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3905654A (en) * 1973-11-14 1975-09-16 Kelsey Hayes Co Skid control system for dual brake
US3945988A (en) * 1974-07-16 1976-03-23 Pushpa Khann Process for isolation of insulin from plant source
US4043989A (en) * 1975-09-11 1977-08-23 Syva Company Oxazepam derivatives for immunoassay reagents
US4069105A (en) * 1977-03-03 1978-01-17 Syva Company Lidocaine antigens and antibodies
US4156081A (en) * 1977-04-15 1979-05-22 Syva Company Theophylline antigens and antibodies
JPS57106626A (en) * 1980-12-22 1982-07-02 Teijin Ltd Cytotoxic protein complex and its preparation
US5098710A (en) * 1987-06-18 1992-03-24 Yaguang Liu Production of kuguasu
US5086043A (en) * 1987-06-18 1992-02-04 Yaguang Liu Production of Saponins of Lichi
US4985248A (en) * 1987-06-18 1991-01-15 Yaguang Liu Pharmaceutical composition containing a safe extracts of fruits and vegetables for the treating and preventing of diabetes
ES2128362T3 (es) * 1991-12-03 1999-05-16 Proteus Molecular Design Fragmentos de proteinas de prion.
US5750361A (en) * 1995-11-02 1998-05-12 The Regents Of The University Of California Formation and use of prion protein (PRP) complexes

Also Published As

Publication number Publication date
EP1005274B1 (en) 2008-08-06
US6852695B2 (en) 2005-02-08
DE69839842D1 (de) 2008-09-18
ES2310006T3 (es) 2008-12-16
CA2285452A1 (en) 1998-10-08
AU749792B2 (en) 2002-07-04
US6127338A (en) 2000-10-03
CN1255044A (zh) 2000-05-31
US6391854B1 (en) 2002-05-21
EP1005274A4 (en) 2004-09-08
WO1998043484A1 (en) 1998-10-08
JP2002516608A (ja) 2002-06-04
AU6876598A (en) 1998-10-22
JP4156038B2 (ja) 2008-09-24
EP1005274A1 (en) 2000-06-07
US20020193310A1 (en) 2002-12-19
KR20010005917A (ko) 2001-01-15
KR100509438B1 (ko) 2005-08-23

Similar Documents

Publication Publication Date Title
ATE403672T1 (de) Oral aktive fraktion der momordica charantia, ihre aktiven peptide und ihre verwendung bei der behandlung des diabetes
MY137348A (en) Highly selective norepinephrine reuptake inhibitors and methods of using the same
IL112111A0 (en) Peptide derivatives and pharmaceutical compositions containing them
KR930702022A (ko) 인슐린의 경구 투여에 의한 타잎 1 당뇨병의 치료 또는 예방법
SE9503924D0 (sv) Novel opioid peptides
DE69737990D1 (de) Neuer metabotropischer glutamat-rezeptor vom menschen
DE69003015D1 (de) Behandlung von Störungen in der Postmenopause.
ID24901A (id) Metode pengobatan keadaan terkoagulasi tinggi atau defisiensi protein c yang diperoleh
CA2274686A1 (en) Sulfonic acid or sulfonylamino n-(heteroaralkyl)-azaheterocyclylamide compounds
JPH0517365A (ja) テストステロン ５α−レダクターゼ阻害剤
BR9708388A (pt) Solução aquosa de hemoglobina polimerizada piridoxilada e processo de sua preparação.
CA2003856A1 (en) Therapeutic agent for renal disorders
AU1458495A (en) Application of riluzole in the treatment of mitochondrial diseases
MY107235A (en) Use of tenidap to inhibit activation of collagenase and to inhibit the activity of myeloperoxidase.
DE69630583D1 (de) Peptide, bronchodilator und den blutstrom verbesserndes mittel
AU2173101A (en) Use of carboxy compounds such as 2(4-acetoxyphenyl)-2-chloro-N-methyl-ethylammonium chloride as anti-inflammatory agents
NZ303993A (en) Pharmaceutical compositions containing aminotetralin derivatives for treating cardiac disorders
TR199900013T2 (xx) Yeni bile�ikler.
RU97106986A (ru) Средство и способ лечения ишемического инсульта
ATE275953T1 (de) 2,3 diaryl-1-benzopyrame zur behandlung von dermatitis
JPS6322524A (ja) 鎮痛剤として有用な環状及び架橋環状ソマトスタチンアナログ
DE2729096A1 (de) Verwendung der inhibitorpeptide der angiotensinumwandlung als mittel zur senkung des blutzuckerspiegels
RU96113185A (ru) Раствор для лечения заболеваний и повреждений роговицы "кератан-с"
JPH04198135A (ja) 外用剤
SE9502877D0 (sv) Novel opioid peptides

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties