ATE396751T1 - Cyclodextrine tragende biologische materialien mit verbesserten absorptionseigenschaften zur progressiven und verzögerten freisetzung von therapeutischen molekülen - Google Patents

Cyclodextrine tragende biologische materialien mit verbesserten absorptionseigenschaften zur progressiven und verzögerten freisetzung von therapeutischen molekülen

Info

Publication number
ATE396751T1
ATE396751T1 AT05817573T AT05817573T ATE396751T1 AT E396751 T1 ATE396751 T1 AT E396751T1 AT 05817573 T AT05817573 T AT 05817573T AT 05817573 T AT05817573 T AT 05817573T AT E396751 T1 ATE396751 T1 AT E396751T1
Authority
AT
Austria
Prior art keywords
biomaterial
progressive
delayed release
materials containing
biological materials
Prior art date
Application number
AT05817573T
Other languages
English (en)
Inventor
Bernard Martel
Nicolas Blanchemain
Francois Boschin
Stephan Haulon
Elisabeth Delcourt-Debruyne
Michel Morcellet
Hartmut Hildebrand
Original Assignee
Univ Lille Sciences Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Lille Sciences Tech filed Critical Univ Lille Sciences Tech
Application granted granted Critical
Publication of ATE396751T1 publication Critical patent/ATE396751T1/de

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/146Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08Materials for coatings
    • A61L29/085Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/146Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/80Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
    • A61L2300/802Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
AT05817573T 2004-11-15 2005-11-15 Cyclodextrine tragende biologische materialien mit verbesserten absorptionseigenschaften zur progressiven und verzögerten freisetzung von therapeutischen molekülen ATE396751T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0412086A FR2877846B1 (fr) 2004-11-15 2004-11-15 Biomateriaux porteurs de cyclodextrines aux proprietes d'absorption ameliorees et de liberation progressive et retardee de molecules therapeutiques

Publications (1)

Publication Number Publication Date
ATE396751T1 true ATE396751T1 (de) 2008-06-15

Family

ID=34953530

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05817573T ATE396751T1 (de) 2004-11-15 2005-11-15 Cyclodextrine tragende biologische materialien mit verbesserten absorptionseigenschaften zur progressiven und verzögerten freisetzung von therapeutischen molekülen

Country Status (13)

Country Link
US (1) US8906403B2 (de)
EP (1) EP1824531B1 (de)
JP (1) JP5329090B2 (de)
CN (1) CN101080247A (de)
AT (1) ATE396751T1 (de)
AU (1) AU2005303626B2 (de)
CA (1) CA2587435C (de)
DE (1) DE602005007264D1 (de)
DK (1) DK1824531T3 (de)
ES (1) ES2308579T3 (de)
FR (1) FR2877846B1 (de)
PT (1) PT1824531E (de)
WO (1) WO2006051227A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2086603B1 (de) * 2006-11-06 2013-01-02 Laboratoires Perouse Verfahren zur herstellung einer implantierbaren prothese aus einem körper mit poröser basis und relevante prothese und ihre verwendung
FR2908047B1 (fr) * 2006-11-06 2009-10-30 Perouse Soc Par Actions Simpli Procede de preparation d'une prothese tubulaire implantable a partir d'un corps tubulaire de base en materiau poreux, et prothese associee
FR2922774B1 (fr) * 2007-10-26 2010-09-17 Perouse Lab Procede de preparation d'une prothese implantable a partir d'un corps de base en materiau poreux, prothese et utilisation associees.
WO2008157372A2 (en) 2007-06-14 2008-12-24 Massachusetts Institute Of Technology Self assembled films for protein and drug delivery applications
US9198875B2 (en) 2008-08-17 2015-12-01 Massachusetts Institute Of Technology Controlled delivery of bioactive agents from decomposable films
WO2010141667A1 (en) 2009-06-03 2010-12-09 Case Western Reserve University Therapeutic agent delivery system and method
US9642920B2 (en) 2009-06-03 2017-05-09 Case Western Reserve University Therapeutic agent delivery system and method
RU2494076C1 (ru) * 2012-02-29 2013-09-27 Федеральное государственное бюджетное учреждение науки Институт металлургии и материаловедения им. А.А. Байкова Российской академии наук Способ упрочнения пористой кальцийфосфатной керамики
FR2988300B1 (fr) * 2012-03-26 2014-04-11 Bjr France Dispositif implantable de reparation et de reconstruction osseuse apte a adsorber des agents bioactifs et procedes de fabrication d'un tel dispositif
EP2841056A4 (de) 2012-04-23 2015-09-16 Massachusetts Inst Technology Stabile schichtweise beschichtete teilchen
US10092653B2 (en) * 2012-09-13 2018-10-09 W. L. Gore & Associates, Inc. Polytetrafluoroethylene co-polymer emulsions
FR3000080B1 (fr) * 2012-12-20 2015-01-30 Oreal Polycondensat de cyclodextrine insoluble dans l'eau ; utilisations comme agent de capture
WO2014134029A1 (en) 2013-02-26 2014-09-04 Massachusetts Institute Of Technology Nucleic acid particles, methods and use thereof
JP6154163B2 (ja) * 2013-03-15 2017-06-28 独立行政法人国立高等専門学校機構 水不溶性シクロデキストリンポリマーおよびその製造方法
WO2014150074A1 (en) 2013-03-15 2014-09-25 Massachusetts Institute Of Technology Compositions and methods for nucleic acid delivery
JP5796728B1 (ja) 2014-11-17 2015-10-21 株式会社ライラック研究所 創傷治癒を促進し生体諸臓器の被覆(コーチング)及び庇護を目的とした生体皮膜剤。
CN104628893B (zh) * 2015-02-06 2017-12-19 安徽理工大学 一种利用化学反应与减压蒸馏耦合制备环糊精基聚合物吸附材料的方法
FR3038318B1 (fr) * 2015-07-02 2017-08-04 Univ De Lille 1 Sciences Et Technologies Procede de fabrication d'hydrogel a base de chitosan et de polyelectrolytes charges negativement et materiau poreux alveolaire issu dudit hydrogel
CN105561406A (zh) * 2016-02-15 2016-05-11 丹阳纳瑞康纳米科技有限公司 一种含复合药物涂层的血管支架
BR112019020724A2 (pt) * 2017-04-05 2020-05-12 Gelesis, Llc Materiais superabsorventes melhorados e métodos de produção dos mesmos
KR102101936B1 (ko) * 2017-10-19 2020-04-17 서울대학교병원 의료용 임플란트 표면 개질용 조성물 및 그에 의해 표면 개질된 의료용 임플란트
US11419947B2 (en) 2017-10-30 2022-08-23 Massachusetts Institute Of Technology Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
FR3080539B1 (fr) * 2018-04-27 2020-05-08 Cousin Biotech Dispositif implantable comprenant une piece textile comprenant des fils multifilamentaires et/ou des fils files de fibres revetu(e)s en tout ou partie d'un polymere de cyclodextrine
CN112111024B (zh) * 2020-09-17 2021-09-28 江南大学 一种绿色的酸改性环糊精及其制备方法
CN112877383B (zh) * 2021-01-21 2024-05-28 大连大学 一种固定化脂肪酶催化柠檬酸功能化β-环糊精及其制备方法
US20220240605A1 (en) * 2021-01-29 2022-08-04 Bioserenity Face Mask Having a Combined Biocidal and Electrostatic Treatment
CN113368298B (zh) * 2021-06-09 2022-07-15 刘长城 一种具有抗菌效果的骨科医用粘合材料及其制备方法
CN114028609A (zh) * 2021-12-10 2022-02-11 中新国际联合研究院 一种电活性口腔引导骨再生屏障膜及其制备方法
CN114702682B (zh) * 2022-04-24 2023-03-14 齐鲁工业大学 一种具有高包埋率和快吸收的双功能糊精制备方法
CN116284504A (zh) * 2023-01-04 2023-06-23 昆明理工大学 一系列交联型环糊精聚合物及其制备方法与应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56123912A (en) * 1980-03-05 1981-09-29 Nitto Electric Ind Co Ltd Drug-containing tape preparation
US5658894A (en) * 1989-04-23 1997-08-19 The Trustees Of The University Of Pennsylvania Compositions for inhibiting restenosis
US5183809A (en) * 1990-02-15 1993-02-02 The Trustees Of The University Of Pennsylvania/Childrens Hospital Corporation Cyclodextrin polymers and cyclodextrins immobilized on a solid surface
US5162430A (en) * 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
US5660854A (en) * 1994-11-28 1997-08-26 Haynes; Duncan H Drug releasing surgical implant or dressing material
DE19849464A1 (de) * 1997-04-30 2000-04-27 Schering Ag Wirkstofffreisetzende Stents, Verfahren zu ihrer Herstellung und ihre Verwendung zur Restenoseprophylaxe
DE19718339A1 (de) * 1997-04-30 1998-11-12 Schering Ag Polymer beschichtete Stents, Verfahren zu ihrer Herstellung und ihre Verwendung zur Restenoseprophylaxe
FR2789685B1 (fr) * 1999-02-15 2001-05-04 Univ Lille Sciences Tech Procede de fabrication de polymeres solubles et insolubles a base de cyclodextrine(s) et/ou de derives de cyclodextrine(s) et polymeres solubles a base de cyclodextrine(s) et/ou de derives de cyclodextrine(s)
FR2789704B1 (fr) * 1999-02-15 2003-09-26 Univ Lille Sciences Tech Procede de traitement d'une fibre ou d'un materiau a base de fibres en vue d'ameliorer ses proprietes adsorbantes et fibre ou materiau a base de fibres presentant des proprietes adsorbantes ameliorees
US6689378B1 (en) * 1999-12-28 2004-02-10 Kimberly-Clark Worldwide, Inc. Cyclodextrins covalently bound to polysaccharides
EP1280559B1 (de) * 2000-05-11 2006-03-08 Eastman Chemical Company Acylierte zyklodextrin guest-inklusion komplexe
JP2002065839A (ja) * 2000-08-31 2002-03-05 Risoo Erudesu:Kk 薬剤等を包接したモノクロロトリアジニル−β−シクロデキストリンを共有結合して有する保健衛生医療用セルロース系繊維ウェブ材

Also Published As

Publication number Publication date
FR2877846A1 (fr) 2006-05-19
DK1824531T3 (da) 2008-10-06
EP1824531A1 (de) 2007-08-29
JP2008519626A (ja) 2008-06-12
ES2308579T3 (es) 2008-12-01
AU2005303626B2 (en) 2010-12-09
DE602005007264D1 (de) 2008-07-10
CN101080247A (zh) 2007-11-28
WO2006051227A1 (fr) 2006-05-18
EP1824531B1 (de) 2008-05-28
US20080254094A1 (en) 2008-10-16
FR2877846B1 (fr) 2008-12-05
CA2587435C (fr) 2011-06-14
US8906403B2 (en) 2014-12-09
AU2005303626A1 (en) 2006-05-18
CA2587435A1 (fr) 2006-05-18
PT1824531E (pt) 2008-09-08
JP5329090B2 (ja) 2013-10-30

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