ATE394390T1 - Optisch aktive 1,4-benzodioxin-2-carbonsäure- derivate und verfahren zu ihrer herstellung - Google Patents
Optisch aktive 1,4-benzodioxin-2-carbonsäure- derivate und verfahren zu ihrer herstellungInfo
- Publication number
- ATE394390T1 ATE394390T1 AT99931516T AT99931516T ATE394390T1 AT E394390 T1 ATE394390 T1 AT E394390T1 AT 99931516 T AT99931516 T AT 99931516T AT 99931516 T AT99931516 T AT 99931516T AT E394390 T1 ATE394390 T1 AT E394390T1
- Authority
- AT
- Austria
- Prior art keywords
- optically active
- acid derivatives
- benzodioxin
- production
- carbonic acid
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- -1 (R)-1-phenylethylamino Chemical group 0.000 abstract 3
- 150000001298 alcohols Chemical class 0.000 abstract 2
- 125000004769 (C1-C4) alkylsulfonyl group Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004391 aryl sulfonyl group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP21782998 | 1998-07-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE394390T1 true ATE394390T1 (de) | 2008-05-15 |
Family
ID=16710410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99931516T ATE394390T1 (de) | 1998-07-31 | 1999-07-23 | Optisch aktive 1,4-benzodioxin-2-carbonsäure- derivate und verfahren zu ihrer herstellung |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US6222050B1 (de) |
| EP (1) | EP1020458B1 (de) |
| KR (1) | KR100523713B1 (de) |
| AT (1) | ATE394390T1 (de) |
| CA (1) | CA2303195C (de) |
| DE (1) | DE69938645D1 (de) |
| TW (1) | TW531536B (de) |
| WO (1) | WO2000006562A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100523713B1 (ko) * | 1998-07-31 | 2005-10-26 | 닛신 파마 가부시키가이샤 | 광학활성 1,4-벤조디옥신-2-카르복실산 유도체 및 그의제조방법 |
| US7241272B2 (en) | 2001-11-13 | 2007-07-10 | Baxter International Inc. | Method and composition for removing uremic toxins in dialysis processes |
| JPWO2004070045A1 (ja) * | 2003-02-10 | 2006-05-25 | 日清ファルマ株式会社 | 光学活性な６−ホルミル−１，４−ベンゾジオキシン−２−カルボン酸誘導体の製造方法 |
| US8029454B2 (en) * | 2003-11-05 | 2011-10-04 | Baxter International Inc. | High convection home hemodialysis/hemofiltration and sorbent system |
| WO2005083102A1 (ja) * | 2004-03-01 | 2005-09-09 | Mercian Corporation | 光学活性1,4-ベンゾジオキシン-2-カルボン酸誘導体の製造方法 |
| US8057423B2 (en) * | 2007-07-05 | 2011-11-15 | Baxter International Inc. | Dialysis system having disposable cassette |
| US8114276B2 (en) * | 2007-10-24 | 2012-02-14 | Baxter International Inc. | Personal hemodialysis system |
| US9415150B2 (en) * | 2007-11-09 | 2016-08-16 | Baxter Healthcare S.A. | Balanced flow dialysis machine |
| CN105541537B (zh) * | 2016-03-28 | 2018-01-23 | 山东成泰化工有限公司 | 一种调整碳四烯烃异构反应选择性的调节剂及方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4118507A (en) * | 1977-03-17 | 1978-10-03 | Shell Oil Company | Benzodioxincarboxamide lipogenesis inhibitors |
| US4208424A (en) | 1979-04-26 | 1980-06-17 | Shell Oil Company | Lipogenesis inhibition by certain esters of substituted benzodioxincarboxylic acids |
| FR2704857B1 (fr) | 1993-05-07 | 1995-06-23 | Adir | Nouvelles benzodioxines substituées, leur procédé de préparation et les compositions pharmaceutiques les contenant. |
| US5482971A (en) * | 1993-10-01 | 1996-01-09 | American Cyanamid Company | Beta3 -adrenergic agents and their use in pharmaceutical compositions |
| WO1996035685A1 (en) | 1995-05-12 | 1996-11-14 | Nisshin Flour Milling Co., Ltd. | 1,4-benzodioxin derivatives |
| JP2001507704A (ja) | 1996-12-30 | 2001-06-12 | アメリカン・ホーム・プロダクツ・コーポレイション | 抗肥満薬としての置換ベンゾ［１，４］ジオキサン |
| JP4233135B2 (ja) | 1997-11-11 | 2009-03-04 | 日清ファルマ株式会社 | ６−（２−（ｒ）−アミノプロピル）−１，４−ベンゾジオキサン−２−（ｒ）−カルボン酸誘導体およびその製造方法 |
| KR100523713B1 (ko) * | 1998-07-31 | 2005-10-26 | 닛신 파마 가부시키가이샤 | 광학활성 1,4-벤조디옥신-2-카르복실산 유도체 및 그의제조방법 |
-
1999
- 1999-07-23 KR KR10-2000-7003479A patent/KR100523713B1/ko not_active Expired - Fee Related
- 1999-07-23 CA CA002303195A patent/CA2303195C/en not_active Expired - Fee Related
- 1999-07-23 US US09/509,200 patent/US6222050B1/en not_active Expired - Fee Related
- 1999-07-23 DE DE69938645T patent/DE69938645D1/de not_active Expired - Fee Related
- 1999-07-23 EP EP99931516A patent/EP1020458B1/de not_active Expired - Lifetime
- 1999-07-23 WO PCT/JP1999/003963 patent/WO2000006562A1/ja not_active Ceased
- 1999-07-23 AT AT99931516T patent/ATE394390T1/de not_active IP Right Cessation
- 1999-07-30 TW TW088113034A patent/TW531536B/zh not_active IP Right Cessation
-
2001
- 2001-01-22 US US09/765,424 patent/US6329533B2/en not_active Expired - Fee Related
- 2001-10-18 US US09/978,690 patent/US6509482B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2303195C (en) | 2008-01-15 |
| KR100523713B1 (ko) | 2005-10-26 |
| US6509482B2 (en) | 2003-01-21 |
| US6222050B1 (en) | 2001-04-24 |
| CA2303195A1 (en) | 2000-02-10 |
| US20020028957A1 (en) | 2002-03-07 |
| US20010018529A1 (en) | 2001-08-30 |
| TW531536B (en) | 2003-05-11 |
| US6329533B2 (en) | 2001-12-11 |
| DE69938645D1 (de) | 2008-06-19 |
| EP1020458B1 (de) | 2008-05-07 |
| WO2000006562A1 (en) | 2000-02-10 |
| EP1020458A1 (de) | 2000-07-19 |
| KR20010024367A (ko) | 2001-03-26 |
| EP1020458A4 (de) | 2004-09-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |