ATE390447T1 - Konjugationsreaktionen - Google Patents

Konjugationsreaktionen

Info

Publication number
ATE390447T1
ATE390447T1 AT04702752T AT04702752T ATE390447T1 AT E390447 T1 ATE390447 T1 AT E390447T1 AT 04702752 T AT04702752 T AT 04702752T AT 04702752 T AT04702752 T AT 04702752T AT E390447 T1 ATE390447 T1 AT E390447T1
Authority
AT
Austria
Prior art keywords
group
bromo
initiator
methyl
propionic acid
Prior art date
Application number
AT04702752T
Other languages
English (en)
Inventor
Andrew Lewis
Simon Leppard
Original Assignee
Biocompatibles Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocompatibles Uk Ltd filed Critical Biocompatibles Uk Ltd
Application granted granted Critical
Publication of ATE390447T1 publication Critical patent/ATE390447T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F246/00Copolymers in which the nature of only the monomers in minority is defined
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/091Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/5537Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom the heteroring containing the structure -C(=O)-N-C(=O)- (both carbon atoms belong to the heteroring)
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F4/00Polymerisation catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT04702752T 2003-01-16 2004-01-16 Konjugationsreaktionen ATE390447T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0301014.7A GB0301014D0 (en) 2003-01-16 2003-01-16 Conjugation reactions

Publications (1)

Publication Number Publication Date
ATE390447T1 true ATE390447T1 (de) 2008-04-15

Family

ID=9951273

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04702752T ATE390447T1 (de) 2003-01-16 2004-01-16 Konjugationsreaktionen

Country Status (6)

Country Link
US (2) US8053520B2 (de)
EP (1) EP1592719B1 (de)
AT (1) ATE390447T1 (de)
DE (1) DE602004012713T2 (de)
GB (1) GB0301014D0 (de)
WO (1) WO2004063237A1 (de)

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WO2008098930A1 (en) 2007-02-14 2008-08-21 Biocompatibes Uk Limited Derivatisation of biological molecules
WO2009053700A1 (en) * 2007-10-23 2009-04-30 Cancer Research Technology Limited Modification of nucleic acid-containing biological entities
DK2260873T3 (da) 2009-06-08 2019-09-16 Biocompatibles Uk Ltd Pcylering af proteiner
WO2011075185A1 (en) 2009-12-18 2011-06-23 Oligasis Targeted drug phosphorylcholine polymer conjugates
KR20130097636A (ko) * 2010-04-15 2013-09-03 올리가시스 고분자량 쌍성이온-함유 중합체
WO2015035342A2 (en) 2013-09-08 2015-03-12 Oligasis Llc Factor viii zwitterionic polymer conjugates
US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
JP6849590B2 (ja) 2014-10-17 2021-03-24 コディアック サイエンシーズ インコーポレイテッドKodiak Sciences Inc. ブチリルコリンエステラーゼ両性イオン性ポリマーコンジュゲート
BR112018013407A2 (en) 2015-12-30 2018-12-18 Kodiak Sciences Inc. antibodies and conjugates thereof
SG11202008242XA (en) 2018-03-02 2020-09-29 Kodiak Sciences Inc Il-6 antibodies and fusion constructs and conjugates thereof
US11912784B2 (en) 2019-10-10 2024-02-27 Kodiak Sciences Inc. Methods of treating an eye disorder

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US5162430A (en) * 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
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Also Published As

Publication number Publication date
EP1592719A1 (de) 2005-11-09
WO2004063237A1 (en) 2004-07-29
DE602004012713T2 (de) 2009-04-09
US8445612B2 (en) 2013-05-21
US8053520B2 (en) 2011-11-08
GB0301014D0 (en) 2003-02-19
DE602004012713D1 (de) 2008-05-08
US20120016082A1 (en) 2012-01-19
EP1592719B1 (de) 2008-03-26
US20060135714A1 (en) 2006-06-22

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