ATE389415T1 - Verfahren und mittel zur erhöhung der darmabsorption - Google Patents

Verfahren und mittel zur erhöhung der darmabsorption

Info

Publication number
ATE389415T1
ATE389415T1 AT03760706T AT03760706T ATE389415T1 AT E389415 T1 ATE389415 T1 AT E389415T1 AT 03760706 T AT03760706 T AT 03760706T AT 03760706 T AT03760706 T AT 03760706T AT E389415 T1 ATE389415 T1 AT E389415T1
Authority
AT
Austria
Prior art keywords
increase intestinal
egf
intestinal absorption
relates
producing
Prior art date
Application number
AT03760706T
Other languages
English (en)
Inventor
Lothar Steidler
Original Assignee
Actogenix Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actogenix Nv filed Critical Actogenix Nv
Application granted granted Critical
Publication of ATE389415T1 publication Critical patent/ATE389415T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/485Epidermal growth factor [EGF], i.e. urogastrone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1808Epidermal growth factor [EGF] urogastrone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Surgery (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Radio Relay Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT03760706T 2002-06-19 2003-06-19 Verfahren und mittel zur erhöhung der darmabsorption ATE389415T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02077532 2002-06-19

Publications (1)

Publication Number Publication Date
ATE389415T1 true ATE389415T1 (de) 2008-04-15

Family

ID=29797233

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03760706T ATE389415T1 (de) 2002-06-19 2003-06-19 Verfahren und mittel zur erhöhung der darmabsorption

Country Status (9)

Country Link
US (1) US7601799B2 (de)
EP (1) EP1513545B1 (de)
JP (1) JP2005529622A (de)
AT (1) ATE389415T1 (de)
AU (1) AU2003250250B2 (de)
CA (1) CA2489930A1 (de)
DE (1) DE60319822T2 (de)
ES (1) ES2302945T3 (de)
WO (1) WO2004001020A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003250250B2 (en) 2002-06-19 2008-02-14 Intrexon Actobiotics Nv Methods and means to promote gut absorption
JP5410759B2 (ja) 2005-11-29 2014-02-05 アクトジェニックス・エヌブイ 抗原に対する粘膜寛容の誘導
EP2125010B1 (de) * 2007-01-25 2014-06-04 Actogenix N.V. Behandlung von immunkrankheiten durch mukosale abgabe von antigenen mit genetisch modifiziertem lactobacillus
EP3933029A3 (de) * 2008-09-29 2022-03-23 Intrexon Actobiotics NV Reduzierte mikrobenkolonisierung an der schleimhaut
EP2451467B1 (de) * 2010-01-14 2016-12-21 INSERM - Institut National de la Santé et de la Recherche Médicale Rekombinante probiotische bakterien zur vorbeugung und behandlung der chronisch-entzündlichen darmerkrankung und des reizdarmsyndroms
AU2013240289B2 (en) 2012-03-29 2018-01-25 Therabiome, Llc Gastrointestinal site-specific oral vaccination formulations active on the ileum and appendix
NZ711298A (en) 2013-03-14 2021-07-30 Therabiome Llc Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents
CN103710351B (zh) * 2013-12-23 2015-12-09 江苏众红生物工程创药研究院有限公司 表皮生长因子重组乳酸菌及其应用
CN107325998A (zh) * 2017-06-20 2017-11-07 江西嘉博生物工程有限公司 一种表达猪表皮生长因子基因的重组乳酸乳球菌及构建方法
JP7316802B2 (ja) * 2019-02-19 2023-07-28 雪印メグミルク株式会社 糖吸収促進用組成物
CN116676246A (zh) * 2023-06-16 2023-09-01 华中农业大学 重组乳酸乳球菌、益生菌制剂、构建方法、cECF表达方法及应用

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4100495A (en) * 1975-11-27 1978-07-11 Cselt - Centro Studi E Laboratori Telecomunicazioni Adaptive method of and means for recovering digital signals
US4190495A (en) * 1976-09-27 1980-02-26 Research Corporation Modified microorganisms and method of preparing and using same
US4874702A (en) * 1980-09-08 1989-10-17 Biogen, Inc. Vectors and methods for making such vectors and for expressive cloned genes
US4888170A (en) * 1981-10-22 1989-12-19 Research Corporation Vaccines obtained from antigenic gene products of recombinant genes
US5417986A (en) * 1984-03-16 1995-05-23 The United States Of America As Represented By The Secretary Of The Army Vaccines against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres
US5032510A (en) * 1984-09-26 1991-07-16 Eli Lilly And Company Method for expression and secretion in bacillus
DE3578852D1 (de) 1984-09-26 1990-08-30 Lilly Co Eli Verfahren zur expression und sekretion in bacillus.
EP0681026A1 (de) 1987-03-02 1995-11-08 Whitehead Institute For Biomedical Research Rekombinant-mykobakterielle Impfstoffe
US5504005A (en) 1987-03-02 1996-04-02 Albert Einstein College Of Medicine Of Yeshiva University Recombinant mycobacterial vaccine
US5591632A (en) 1987-03-02 1997-01-07 Beth Israel Hospital Recombinant BCG
US5330753A (en) * 1987-04-29 1994-07-19 President And Fellows Of Harvard College Cholera vaccines
US6130082A (en) * 1988-05-05 2000-10-10 American Cyanamid Company Recombinant flagellin vaccines
US5972685A (en) 1988-07-21 1999-10-26 Iowa State University Research Foundation, Inc. Oral administration of coprostanol producing microorganisms to humans to decrease plasma cholesterol concentration
IE892131A1 (en) 1989-06-30 1991-01-02 Univ Cork Marker genes for genetic manipulation
US5149532A (en) 1989-11-01 1992-09-22 Cedars Sinai Medical Center Method of vaccine or toxoid preparation and immunization by colonization with recombinant microorganisms
DE4006521A1 (de) 1990-03-02 1991-09-05 Bayer Ag Zuckerhaltige polymere zur umhuellung und einbettung von arzneistoffen
GB9006400D0 (en) 1990-03-22 1990-05-23 Ciba Geigy Ag Bacterial vectors
IL99097A0 (en) * 1990-09-05 1992-07-15 Akzo Nv Haemophilus paragallinarum vaccine
KR100240182B1 (ko) * 1991-03-05 2000-01-15 레슬리 제인 에드워즈 재조합 단백질을 발헨하는 약독해진 박테리아를 함유하는 백신
ES2174838T3 (es) 1991-10-07 2002-11-16 Brigham & Womens Hospital Metodo para aumentar la absorcion del intestino.
IL103530A0 (en) * 1991-10-25 1993-03-15 Duphar Int Res Treponema hyodysenteriae vaccine
GB2278358B (en) 1992-02-27 1995-07-26 Lynxvale Ltd Heterologous gene expression in Lactococcus,and the expression products therefrom
US5455034A (en) * 1992-06-26 1995-10-03 Kansas State University Research Foundation Fusobacterium necrophorum leukotoxoid vaccine
DE4231764A1 (de) 1992-09-23 1994-03-24 Inst Pflanzengenetik & Kultur Verfahren zur chromosomalen Integration eines Produkt-Gens
US5691185A (en) 1993-10-08 1997-11-25 Chr. Hansen A/S Lactic acid bacterial suppressor mutants and their use as selective markers and as means of containment in lactic acid bacteria
NZ274482A (en) 1993-10-13 1997-09-22 Gx Biosystems As Cells transformed with a truncated and/or mutated staphylococcus aureus nuclease and their use in immunological, pesticidal and environmental pollutant-degrading compositions
IT1270123B (it) * 1994-10-05 1997-04-28 Dompe Spa Composizioni farmaceutiche contenenti microorganismi ingegnerizzati e loro uso per terapia
US5733540A (en) * 1995-03-08 1998-03-31 Lee; Peter Poon-Hang Protection from viral infection via colonization of mucosal membranes with genetically modified bacteria
US5753622A (en) 1995-05-10 1998-05-19 University Technologies International, Inc. Use of epidermal growth factor as a gastrointestinal therapeutic agent
JPH11507532A (ja) 1995-06-07 1999-07-06 ワシントン ユニバーシティ 環境に制限される生存能を有する組換え細菌システム
US5824538A (en) * 1995-09-06 1998-10-20 The United States Of America As Represented By The Secretary Of The Army Shigella vector for delivering DNA to a mammalian cell
GB9518323D0 (en) * 1995-09-07 1995-11-08 Steidler Lothar Materials and methods relating to the attachment and display of substances on cell surfaces
GB9521568D0 (en) 1995-10-20 1995-12-20 Lynxvale Ltd Delivery of biologically active polypeptides
AU722327B2 (en) * 1996-04-19 2000-07-27 Henry M. Jackson Foundation For The Advancement Of Military Medicine Method of stimulating an immune response by administration of host organisms that express intimin alone or as a fusion protein with one or more other antigens
US5972887A (en) 1996-09-19 1999-10-26 The Nemours Foundation Treatment of intestinal epithelial cell malfunctions with Hepatocyte Growth Factor
GB9700939D0 (en) 1997-01-17 1997-03-05 Microbial Technics Limited Therapy
AU766257C (en) 1998-05-07 2004-06-03 Universite Libre De Bruxelles Cytotoxin-based biological containment
US6190669B1 (en) * 1998-05-13 2001-02-20 University Of Maryland, Baltimore Attenuated mutants of salmonella which constitutively express the Vi antigen
WO2000001799A2 (en) 1998-07-03 2000-01-13 Chr. Hansen A/S Method of preventing bacteriophage infection of bacterial cultures
AU757343B2 (en) 1998-09-28 2003-02-20 Capsugel Belgium Nv Enteric and colonic delivery using HPMC capsules
WO2000022909A2 (en) 1998-10-19 2000-04-27 Biotech Australia Pty. Limited Systems for oral delivery
DE69914932T2 (de) 1998-10-20 2004-12-09 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw. Verwendung eines zytokine-produzierenden lactococcus stammes zur behandlung von kolitis
CA2446776C (en) 2001-05-03 2011-07-12 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Self-containing lactococcus strain
EP1319410A1 (de) * 2001-12-11 2003-06-18 Société des Produits Nestlé S.A. Verwendung von Mikroorganismen zur gezielten Verabreichung von Mitteln in specifischen Teilen des Darms
US20040043003A1 (en) * 2002-01-31 2004-03-04 Wei Chen Clinical grade vectors based on natural microflora for use in delivering therapeutic compositions
AU2003250250B2 (en) 2002-06-19 2008-02-14 Intrexon Actobiotics Nv Methods and means to promote gut absorption
EP1560935A2 (de) 2002-11-15 2005-08-10 VIB vzw Selbst-enthaldender lactobacillus strain

Also Published As

Publication number Publication date
WO2004001020A3 (en) 2004-03-04
US20050158282A1 (en) 2005-07-21
ES2302945T3 (es) 2008-08-01
DE60319822D1 (de) 2008-04-30
WO2004001020A2 (en) 2003-12-31
DE60319822T2 (de) 2009-06-04
AU2003250250A1 (en) 2004-01-06
US7601799B2 (en) 2009-10-13
EP1513545B1 (de) 2008-03-19
EP1513545A2 (de) 2005-03-16
JP2005529622A (ja) 2005-10-06
CA2489930A1 (en) 2003-12-31
AU2003250250B2 (en) 2008-02-14

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