ATE38831T1 - Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. - Google Patents
Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.Info
- Publication number
- ATE38831T1 ATE38831T1 AT84730009T AT84730009T ATE38831T1 AT E38831 T1 ATE38831 T1 AT E38831T1 AT 84730009 T AT84730009 T AT 84730009T AT 84730009 T AT84730009 T AT 84730009T AT E38831 T1 ATE38831 T1 AT E38831T1
- Authority
- AT
- Austria
- Prior art keywords
- carbacyclines
- medicines
- processes
- new
- production
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
- C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
- C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyrane Compounds (AREA)
- Basic Packing Technique (AREA)
- Ink Jet Recording Methods And Recording Media Thereof (AREA)
- Lubricants (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19833306123 DE3306123A1 (de) | 1983-02-18 | 1983-02-18 | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| EP84730009A EP0119949B1 (de) | 1983-02-18 | 1984-02-09 | Neue Carbacycline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE38831T1 true ATE38831T1 (de) | 1988-12-15 |
Family
ID=6191513
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT84730009T ATE38831T1 (de) | 1983-02-18 | 1984-02-09 | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5013758A (enExample) |
| EP (1) | EP0119949B1 (enExample) |
| JP (1) | JPH0611726B2 (enExample) |
| AT (1) | ATE38831T1 (enExample) |
| AU (1) | AU580728B2 (enExample) |
| CA (1) | CA1251200A (enExample) |
| CS (1) | CS270552B2 (enExample) |
| DD (1) | DD216448A5 (enExample) |
| DE (2) | DE3306123A1 (enExample) |
| DK (1) | DK155828C (enExample) |
| ES (1) | ES8500209A1 (enExample) |
| FI (1) | FI78065C (enExample) |
| GR (1) | GR81961B (enExample) |
| HU (1) | HU191994B (enExample) |
| IE (1) | IE56703B1 (enExample) |
| IL (1) | IL70905A (enExample) |
| NO (1) | NO157060C (enExample) |
| NZ (1) | NZ207061A (enExample) |
| PH (1) | PH21468A (enExample) |
| SU (1) | SU1384196A3 (enExample) |
| YU (1) | YU45173B (enExample) |
| ZA (1) | ZA841198B (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3225287A1 (de) * | 1982-07-02 | 1984-01-05 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacyclinamide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3608088C2 (de) * | 1986-03-07 | 1995-11-16 | Schering Ag | Pharmazeutische Präparate, enthaltend Cyclodextrinclathrate von Carbacyclinderivaten |
| DE3610556A1 (de) * | 1986-03-26 | 1987-10-01 | Schering Ag | 7-oxoprostacyclinderivate und verfahren zu ihrer herstellung |
| DE3727065A1 (de) * | 1987-08-11 | 1989-02-23 | Schering Ag | Verfahren zur herstellung von e/z-gemischen von 2-(bicyclo-(3.3.0)-octan-3-yliden) -essigsaeurederivaten mit ueberwiegendem e- oder z-anteil |
| US5169960A (en) * | 1987-08-11 | 1992-12-08 | Schering Aktiengesellschaft | Process for the production of E/Z mixtures of 2-(bicyclo[3.3.0]octan-3-ylidene)-acetic acid derivatives with predominant E or Z portion |
| US5371284A (en) * | 1987-09-03 | 1994-12-06 | Schering Corporation | Phenyl acetylenic acetals |
| DE3835162A1 (de) * | 1988-10-13 | 1990-04-19 | Schering Ag | (1s,2s,3r,5r)-2-((3s)-2-halogen-3-hydroxy-1-alken(inyl))-3-trialkylsilyloxy-7,7-(2,2-dimethyl-trimethylendioxy)-bicyclo-(3.3.0)-octan-verbindungen und verfahren zu deren herstellung |
| DE3909329A1 (de) * | 1989-03-17 | 1990-09-20 | Schering Ag | 20-alkyl-13,14,18,18,19,19-hexadehydro-3- oxa-isocarbacyclin-derivate und ihre pharmazeutische verwendung |
| DE3933523A1 (de) * | 1989-10-05 | 1991-04-11 | Schering Ag | Antimetastatisch wirkende mittel |
| GB9011588D0 (en) * | 1990-05-24 | 1990-07-11 | Wellcome Found | Prostaglandin analogues for use in medicine |
| DE4028864A1 (de) * | 1990-09-07 | 1992-03-12 | Schering Ag | Verfahren zur herstellung von e/z-mischungen von 2-(6-alkyl-bicyclo-(3.3.0)-octan-3-yliden) -essigsaeure-derivaten mit ueberwiegendem anteil des e-isomeren |
| CA2237620A1 (en) * | 1996-09-17 | 1998-03-26 | Toray Industries, Inc. | Platelet function increment agent and therapeutic method for thrombocytopathy |
| KR20070054644A (ko) * | 2004-07-26 | 2007-05-29 | 액테리온 파마슈티칼 리미티드 | 미립자 제형으로 흡입된 일로프로스트에 의한 폐고혈압의치료 |
| EP2269611B1 (en) | 2006-11-16 | 2016-03-23 | Gemmus Pharma Inc. | EP2 and EP4 agonists as agents for the treatment of influenza A viral infection |
| BR112012008959A2 (pt) | 2009-10-14 | 2019-09-24 | Gemmus Pharma Inc | tratamento de terapia de combinação para infecções virais |
| KR101701943B1 (ko) | 2009-11-13 | 2017-02-02 | 도레이 카부시키가이샤 | 당뇨병의 치료 또는 예방약 |
| US20160184387A1 (en) | 2013-08-09 | 2016-06-30 | Dominique Charmot | Compounds and methods for inhibiting phosphate transport |
| CN114340631A (zh) | 2019-05-21 | 2022-04-12 | 阿德利克斯股份有限公司 | 用于降低患者的血清磷酸盐的组合 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3048906A1 (de) * | 1980-12-19 | 1982-07-15 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3121155A1 (de) * | 1981-05-22 | 1982-12-09 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
-
1983
- 1983-02-18 DE DE19833306123 patent/DE3306123A1/de not_active Withdrawn
-
1984
- 1984-02-01 IE IE236/84A patent/IE56703B1/en not_active IP Right Cessation
- 1984-02-02 AU AU24015/84A patent/AU580728B2/en not_active Ceased
- 1984-02-07 NZ NZ207061A patent/NZ207061A/en unknown
- 1984-02-08 DK DK055584A patent/DK155828C/da not_active IP Right Cessation
- 1984-02-09 DE DE8484730009T patent/DE3475302D1/de not_active Expired
- 1984-02-09 IL IL70905A patent/IL70905A/xx not_active IP Right Cessation
- 1984-02-09 AT AT84730009T patent/ATE38831T1/de not_active IP Right Cessation
- 1984-02-09 EP EP84730009A patent/EP0119949B1/de not_active Expired
- 1984-02-10 ES ES529636A patent/ES8500209A1/es not_active Expired
- 1984-02-10 YU YU244/84A patent/YU45173B/xx unknown
- 1984-02-10 SU SU843700051A patent/SU1384196A3/ru active
- 1984-02-14 CS CS841036A patent/CS270552B2/cs unknown
- 1984-02-14 JP JP59024556A patent/JPH0611726B2/ja not_active Expired - Lifetime
- 1984-02-16 DD DD84260135A patent/DD216448A5/de not_active IP Right Cessation
- 1984-02-16 FI FI840635A patent/FI78065C/fi not_active IP Right Cessation
- 1984-02-17 PH PH30264A patent/PH21468A/en unknown
- 1984-02-17 NO NO840595A patent/NO157060C/no unknown
- 1984-02-17 CA CA000447678A patent/CA1251200A/en not_active Expired
- 1984-02-17 GR GR73840A patent/GR81961B/el unknown
- 1984-02-17 ZA ZA841198A patent/ZA841198B/xx unknown
- 1984-02-17 HU HU84632A patent/HU191994B/hu not_active IP Right Cessation
-
1989
- 1989-11-13 US US07/434,561 patent/US5013758A/en not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |