ATE386032T1 - Verfahren zur herstellung von alkylmercaptomethylergolinderivaten - Google Patents
Verfahren zur herstellung von alkylmercaptomethylergolinderivatenInfo
- Publication number
- ATE386032T1 ATE386032T1 AT99968403T AT99968403T ATE386032T1 AT E386032 T1 ATE386032 T1 AT E386032T1 AT 99968403 T AT99968403 T AT 99968403T AT 99968403 T AT99968403 T AT 99968403T AT E386032 T1 ATE386032 T1 AT E386032T1
- Authority
- AT
- Austria
- Prior art keywords
- mercaptomethylergoline
- derivatives
- producing alkyl
- unsaturated
- cyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1999MI000146A IT1307934B1 (it) | 1999-01-27 | 1999-01-27 | Processo per la preparazione di derivati alchimercaptometilergolinici. |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE386032T1 true ATE386032T1 (de) | 2008-03-15 |
Family
ID=11381633
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99968403T ATE386032T1 (de) | 1999-01-27 | 1999-12-31 | Verfahren zur herstellung von alkylmercaptomethylergolinderivaten |
Country Status (10)
Country | Link |
---|---|
US (1) | US6395901B1 (de) |
EP (1) | EP1147106B1 (de) |
JP (1) | JP4593789B2 (de) |
AT (1) | ATE386032T1 (de) |
CZ (1) | CZ300684B6 (de) |
DE (1) | DE69938153D1 (de) |
IL (2) | IL141920A0 (de) |
IT (1) | IT1307934B1 (de) |
SK (1) | SK286599B6 (de) |
WO (1) | WO2000044748A1 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10053397A1 (de) | 2000-10-20 | 2002-05-02 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
DE10043321B4 (de) * | 2000-08-24 | 2005-07-28 | Neurobiotec Gmbh | Verwendung eines transdermalen therapeutischen Systems zur Behandlung der Parkinsonschen Krankheit, zur Behandlung und Prävention des prämenstruellen Syndroms und zur Lactationshemmung |
DE10064453A1 (de) * | 2000-12-16 | 2002-07-04 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
EP1485382B1 (de) * | 2002-03-15 | 2008-11-19 | Antibioticos S.p.A. | Verfahren zur synthese von pergolid |
ITMI20021755A1 (it) | 2002-08-02 | 2002-11-01 | Poli Ind Chimica Spa | Processo e nuovi intermedi per la preparazione di steroidi ad attivita' progestinica. |
GB0409785D0 (en) * | 2004-04-30 | 2004-06-09 | Resolution Chemicals Ltd | Preparation of cabergoline |
GB0505965D0 (en) * | 2005-03-23 | 2005-04-27 | Resolution Chemicals Ltd | Preparation of cabergoline |
US7339060B2 (en) | 2005-03-23 | 2008-03-04 | Resolution Chemicals, Ltd. | Preparation of cabergoline |
US20070197576A1 (en) * | 2006-02-08 | 2007-08-23 | Resolution Chemicals Limited | Production of Cabergoline and Novel Polymorphic Form Thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0240044B2 (ja) * | 1978-02-08 | 1990-09-10 | Lilly Co Eli | Paakinsonshokogunchiryozai |
US4166182A (en) * | 1978-02-08 | 1979-08-28 | Eli Lilly And Company | 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds |
JPH0240647B2 (ja) * | 1978-02-08 | 1990-09-12 | Lilly Co Eli | Purorakuchinbunpyokuseizai |
US4246265A (en) * | 1979-10-01 | 1981-01-20 | Eli Lilly And Company | 6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds |
US4782152A (en) * | 1985-08-16 | 1988-11-01 | Eli Lilly And Company | Decyanation of pergolide intermediate |
US5463060A (en) * | 1992-05-21 | 1995-10-31 | Eli Lilly And Company | One-pot process |
-
1999
- 1999-01-27 IT IT1999MI000146A patent/IT1307934B1/it active
- 1999-12-31 EP EP99968403A patent/EP1147106B1/de not_active Expired - Lifetime
- 1999-12-31 AT AT99968403T patent/ATE386032T1/de not_active IP Right Cessation
- 1999-12-31 WO PCT/EP1999/010493 patent/WO2000044748A1/en active IP Right Grant
- 1999-12-31 DE DE69938153T patent/DE69938153D1/de not_active Expired - Lifetime
- 1999-12-31 JP JP2000596004A patent/JP4593789B2/ja not_active Expired - Fee Related
- 1999-12-31 SK SK1040-2001A patent/SK286599B6/sk not_active IP Right Cessation
- 1999-12-31 CZ CZ20012640A patent/CZ300684B6/cs not_active IP Right Cessation
- 1999-12-31 IL IL141920??A patent/IL141920A0/xx active IP Right Grant
-
2000
- 2000-12-31 US US09/787,934 patent/US6395901B1/en not_active Expired - Lifetime
-
2001
- 2001-03-08 IL IL141920A patent/IL141920A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CZ20012640A3 (cs) | 2002-02-13 |
US6395901B1 (en) | 2002-05-28 |
IL141920A (en) | 2008-11-26 |
EP1147106B1 (de) | 2008-02-13 |
WO2000044748A1 (en) | 2000-08-03 |
EP1147106A1 (de) | 2001-10-24 |
IT1307934B1 (it) | 2001-11-29 |
DE69938153D1 (de) | 2008-03-27 |
IL141920A0 (en) | 2002-03-10 |
JP4593789B2 (ja) | 2010-12-08 |
SK10402001A3 (sk) | 2002-04-04 |
JP2002535403A (ja) | 2002-10-22 |
SK286599B6 (sk) | 2009-02-05 |
ITMI990146A1 (it) | 2000-07-27 |
CZ300684B6 (cs) | 2009-07-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |