ATE377007T1 - Thiazol- und oxazolderivate, die sich für die behandlung von herzkreislauferkrankungen und ähnlichen erkrankungen eignen - Google Patents
Thiazol- und oxazolderivate, die sich für die behandlung von herzkreislauferkrankungen und ähnlichen erkrankungen eignenInfo
- Publication number
- ATE377007T1 ATE377007T1 AT02738123T AT02738123T ATE377007T1 AT E377007 T1 ATE377007 T1 AT E377007T1 AT 02738123 T AT02738123 T AT 02738123T AT 02738123 T AT02738123 T AT 02738123T AT E377007 T1 ATE377007 T1 AT E377007T1
- Authority
- AT
- Austria
- Prior art keywords
- diseases
- halogen
- optionally substituted
- thiazole
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0113233.1A GB0113233D0 (en) | 2001-05-31 | 2001-05-31 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE377007T1 true ATE377007T1 (de) | 2007-11-15 |
Family
ID=9915638
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02738123T ATE377007T1 (de) | 2001-05-31 | 2002-05-29 | Thiazol- und oxazolderivate, die sich für die behandlung von herzkreislauferkrankungen und ähnlichen erkrankungen eignen |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6867225B2 (https=) |
| EP (1) | EP1392665B1 (https=) |
| JP (1) | JP2004532266A (https=) |
| KR (1) | KR20040007633A (https=) |
| CN (1) | CN1529698A (https=) |
| AT (1) | ATE377007T1 (https=) |
| AU (1) | AU2002312954B2 (https=) |
| BR (1) | BR0210077A (https=) |
| CA (1) | CA2448103A1 (https=) |
| CO (1) | CO5540299A2 (https=) |
| CZ (1) | CZ20033250A3 (https=) |
| DE (1) | DE60223245T2 (https=) |
| ES (1) | ES2295352T3 (https=) |
| GB (1) | GB0113233D0 (https=) |
| HU (1) | HUP0400056A2 (https=) |
| IL (1) | IL158818A0 (https=) |
| MX (1) | MXPA03010584A (https=) |
| NO (1) | NO20035316D0 (https=) |
| PL (1) | PL367215A1 (https=) |
| WO (1) | WO2002096894A1 (https=) |
| ZA (1) | ZA200308864B (https=) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7105551B2 (en) * | 2000-12-20 | 2006-09-12 | Smithkline Beecham Corporation | Thiazole derivatives for treating PPAR related disorders |
| GB0113232D0 (en) * | 2001-05-31 | 2001-07-25 | Glaxo Group Ltd | Chemical process |
| GB0113231D0 (en) * | 2001-05-31 | 2001-07-25 | Glaxo Group Ltd | Chemical compounds |
| AU2003264018A1 (en) * | 2002-08-09 | 2004-02-25 | Astrazeneca Ab | Compounds having an activity at metabotropic glutamate receptors |
| AU2003261935A1 (en) | 2002-09-06 | 2004-03-29 | Takeda Pharmaceutical Company Limited | Furan or thiophene derivative and medicinal use thereof |
| GB0314370D0 (en) * | 2003-06-19 | 2003-07-23 | Glaxo Group Ltd | Chemical compounds |
| WO2005060958A1 (en) * | 2003-12-19 | 2005-07-07 | Kalypsys, Inc. | (5- (2-phenyl)-thiazol-5-ylmethoxy)-indol-1-yl) -acetic acid derivatives and related compounds as modulators of the human ppar-delta receptor for the treatment of metabolic disorders such as type 2 diabetes |
| FR2866339B1 (fr) * | 2004-02-18 | 2006-05-05 | Pf Medicament | Derives de 1,2,4-triazines, leur preparation et leur application en therapeutique humaine |
| DE102004051277A1 (de) | 2004-10-21 | 2006-04-27 | Merck Patent Gmbh | Heterocyclische Carbonylverbindungen |
| FR2882359A1 (fr) * | 2005-02-24 | 2006-08-25 | Negma Lerads Soc Par Actions S | Derives activateurs de ppar, procede de preparation et application en therapeutique |
| FR2882750B1 (fr) * | 2005-03-03 | 2007-05-11 | Pierre Fabre Medicament Sa | Derives de 1,2,4-triazines, leur preparation et leur application en therapeutique humaine |
| WO2007126043A1 (ja) * | 2006-04-27 | 2007-11-08 | Mitsubishi Tanabe Pharma Corporation | チアゾール環を含むカルボン酸誘導体の医薬用途 |
| FR2901792A1 (fr) * | 2006-06-06 | 2007-12-07 | Negma Lerads Soc Par Actions S | DERIVES ACTIVATEURS DE PPARs, PROCEDE DE PREPARATION ET APPLICATION EN THERAPEUTIQUE |
| WO2008035359A2 (en) * | 2006-06-12 | 2008-03-27 | Cadila Healthcare Limited | Oximinophenoxyalkanoic acid and phenylalkanoic acid derivatives |
| JP2010500300A (ja) | 2006-08-08 | 2010-01-07 | サノフィ−アベンティス | アリールアミノアリール−アルキル−置換イミダゾリジン−２，４−ジオン、それらの製造法、それらの化合物を含有する薬剤、およびそれらの使用 |
| EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| DE102007054497B3 (de) | 2007-11-13 | 2009-07-23 | Sanofi-Aventis Deutschland Gmbh | Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung |
| WO2010003624A2 (en) | 2008-07-09 | 2010-01-14 | Sanofi-Aventis | Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof |
| CA2744985C (en) | 2008-12-01 | 2014-05-06 | Mitsubishi Tanabe Pharma Corporation | Carboxylic acid derivative containing thiazole ring useful for the prevention or treatment of hyperlipidemia |
| WO2010068601A1 (en) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof |
| MX2012001729A (es) | 2009-08-26 | 2012-06-13 | Sanofi Sa | Nuevos hidratos cristalinos de fluoroglicosido heteroaromatico, productos farmaceuticos que comprenden estos compuestos, y su empleo. |
| WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| WO2011157827A1 (de) | 2010-06-18 | 2011-12-22 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
| EP2683705B1 (de) | 2011-03-08 | 2015-04-22 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| WO2012120052A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP2683699B1 (de) | 2011-03-08 | 2015-06-24 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| US8828995B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
| WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| EP2760862B1 (en) | 2011-09-27 | 2015-10-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| KR102919209B1 (ko) | 2018-08-10 | 2026-01-28 | 다이아핀 테라퓨틱스, 엘엘씨 | 트리-펩타이드 그리고 대사, 심장혈관 및 염증성 장애의 치료 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5859051A (en) * | 1996-02-02 | 1999-01-12 | Merck & Co., Inc. | Antidiabetic agents |
| US6207422B1 (en) * | 1998-04-17 | 2001-03-27 | The Metrohealth System | Protein that enhances expression of potassium channels on cell surfaces and nucleic acids that encode the same |
| WO2000018903A2 (en) * | 1998-09-29 | 2000-04-06 | The Johns Hopkins University | Inducible genetic suppression of cellular excitability |
| PE20011010A1 (es) * | 1999-12-02 | 2001-10-18 | Glaxo Group Ltd | Oxazoles y tiazoles sustituidos como agonista del receptor activado por el proliferador de peroxisomas humano |
| US7091225B2 (en) | 2000-12-20 | 2006-08-15 | Smithkline Beecham Corporation | Substituted oxazoles and thiazoles as hPPAR alpha agonists |
-
2001
- 2001-05-31 GB GBGB0113233.1A patent/GB0113233D0/en not_active Ceased
-
2002
- 2002-05-29 JP JP2003500073A patent/JP2004532266A/ja active Pending
- 2002-05-29 IL IL15881802A patent/IL158818A0/xx unknown
- 2002-05-29 EP EP02738123A patent/EP1392665B1/en not_active Expired - Lifetime
- 2002-05-29 HU HU0400056A patent/HUP0400056A2/hu unknown
- 2002-05-29 CN CNA028110803A patent/CN1529698A/zh active Pending
- 2002-05-29 MX MXPA03010584A patent/MXPA03010584A/es unknown
- 2002-05-29 KR KR10-2003-7015688A patent/KR20040007633A/ko not_active Withdrawn
- 2002-05-29 CZ CZ20033250A patent/CZ20033250A3/cs unknown
- 2002-05-29 DE DE60223245T patent/DE60223245T2/de not_active Expired - Fee Related
- 2002-05-29 AU AU2002312954A patent/AU2002312954B2/en not_active Ceased
- 2002-05-29 AT AT02738123T patent/ATE377007T1/de not_active IP Right Cessation
- 2002-05-29 ES ES02738123T patent/ES2295352T3/es not_active Expired - Lifetime
- 2002-05-29 BR BR0210077-0A patent/BR0210077A/pt not_active IP Right Cessation
- 2002-05-29 US US10/478,259 patent/US6867225B2/en not_active Expired - Fee Related
- 2002-05-29 CA CA002448103A patent/CA2448103A1/en not_active Abandoned
- 2002-05-29 WO PCT/EP2002/005885 patent/WO2002096894A1/en not_active Ceased
- 2002-05-29 PL PL02367215A patent/PL367215A1/xx not_active Application Discontinuation
-
2003
- 2003-11-13 ZA ZA200308864A patent/ZA200308864B/en unknown
- 2003-11-28 NO NO20035316A patent/NO20035316D0/no not_active Application Discontinuation
- 2003-12-02 CO CO03106071A patent/CO5540299A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200308864B (en) | 2005-02-14 |
| CZ20033250A3 (en) | 2004-03-17 |
| JP2004532266A (ja) | 2004-10-21 |
| ES2295352T3 (es) | 2008-04-16 |
| NO20035316L (no) | 2003-11-28 |
| DE60223245D1 (de) | 2007-12-13 |
| BR0210077A (pt) | 2004-06-22 |
| AU2002312954B2 (en) | 2004-12-02 |
| PL367215A1 (en) | 2005-02-21 |
| GB0113233D0 (en) | 2001-07-25 |
| US20040176427A1 (en) | 2004-09-09 |
| HUP0400056A2 (hu) | 2004-04-28 |
| US6867225B2 (en) | 2005-03-15 |
| NO20035316D0 (no) | 2003-11-28 |
| WO2002096894A1 (en) | 2002-12-05 |
| CN1529698A (zh) | 2004-09-15 |
| EP1392665A1 (en) | 2004-03-03 |
| DE60223245T2 (de) | 2008-08-14 |
| CA2448103A1 (en) | 2002-12-05 |
| MXPA03010584A (es) | 2004-03-09 |
| IL158818A0 (en) | 2004-05-12 |
| EP1392665B1 (en) | 2007-10-31 |
| CO5540299A2 (es) | 2005-07-29 |
| KR20040007633A (ko) | 2004-01-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |