ATE373681T1 - Ester von hyaluronsäure mit rhein, herstellungsverfahren dafür und zusammensetzungen damit - Google Patents
Ester von hyaluronsäure mit rhein, herstellungsverfahren dafür und zusammensetzungen damitInfo
- Publication number
- ATE373681T1 ATE373681T1 AT05708619T AT05708619T ATE373681T1 AT E373681 T1 ATE373681 T1 AT E373681T1 AT 05708619 T AT05708619 T AT 05708619T AT 05708619 T AT05708619 T AT 05708619T AT E373681 T1 ATE373681 T1 AT E373681T1
- Authority
- AT
- Austria
- Prior art keywords
- hyaluronic acid
- esters
- rhine
- compositions
- production method
- Prior art date
Links
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title abstract 4
- 229920002674 hyaluronan Polymers 0.000 title abstract 4
- 229960003160 hyaluronic acid Drugs 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 150000002148 esters Chemical class 0.000 abstract 3
- 125000003158 alcohol group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Rheumatology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000347A ITMI20040347A1 (it) | 2004-02-26 | 2004-02-26 | Nuovo farmaco di associazione |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE373681T1 true ATE373681T1 (de) | 2007-10-15 |
Family
ID=34917538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05708619T ATE373681T1 (de) | 2004-02-26 | 2005-02-25 | Ester von hyaluronsäure mit rhein, herstellungsverfahren dafür und zusammensetzungen damit |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7834173B2 (de) |
| EP (1) | EP1718679B1 (de) |
| JP (2) | JP4870068B2 (de) |
| CN (1) | CN100551932C (de) |
| AT (1) | ATE373681T1 (de) |
| BR (1) | BRPI0507622B8 (de) |
| CA (1) | CA2556942C (de) |
| DE (1) | DE602005002538T2 (de) |
| ES (1) | ES2293538T3 (de) |
| IL (1) | IL177072A (de) |
| IT (1) | ITMI20040347A1 (de) |
| PL (1) | PL1718679T3 (de) |
| PT (1) | PT1718679E (de) |
| RU (1) | RU2383554C2 (de) |
| SI (1) | SI1718679T1 (de) |
| UA (1) | UA91673C2 (de) |
| WO (1) | WO2005085293A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE20060049A1 (en) * | 2006-01-25 | 2007-08-08 | Eurand Pharmaceuticals Ltd | A novel drug delivery system: use of hyaluronic acid as a carrier moleclue for different classes of therapeutic active agents |
| ITMI20062134A1 (it) * | 2006-11-08 | 2008-05-09 | Cbb Net S A | Preparaziobne di esteri della diacereina con acido ialuronico e loro formulazioni per l'impiego farmaceutico |
| US20100136082A1 (en) * | 2006-12-22 | 2010-06-03 | Laboratoire Medidom S.A. | In situ system for intra-articular chondral and osseous tissue repair |
| ITMI20072237A1 (it) * | 2007-11-27 | 2009-05-28 | Sigea Srl | Esteri misti butirrico-formico di polisaccaridi acidi, loro preparazione ed uso come dermocosmetici |
| WO2009133430A1 (en) * | 2008-04-30 | 2009-11-05 | Wockhardt Research Centre | Topical compositions of rhein or diacerein |
| US8722644B2 (en) | 2010-01-04 | 2014-05-13 | Holy Stone Healthcare Co., Ltd. | Mixture of hyaluronic acid for treating and preventing peptic ulcer and duodenal ulcer |
| JP2013533362A (ja) * | 2010-07-29 | 2013-08-22 | ユニバーシティ オブ ジュネーブ | ヒアルロン酸の疎水性有機化合物とのエステル化用のプロセス |
| CN102603575B (zh) * | 2012-01-04 | 2014-08-13 | 丛晓东 | 大精酸共晶物、其制备方法、纯化方法及其在制备治疗糖尿病并发症药物中的应用 |
| GB2501943B (en) * | 2012-05-10 | 2020-09-23 | Zeiss Carl Meditec Ag | Ophthalmic viscoelastic device |
| RU2534789C1 (ru) * | 2013-06-19 | 2014-12-10 | Сергей Алексеевич Успенский | Твердофазный способ получения водорастворимого биоактивного нанокомпозита на основе модифицированной лимонной кислотой гиалуроновой кислоты и наночастиц золота |
| KR101486147B1 (ko) * | 2013-07-09 | 2015-01-23 | 주식회사 엘지생활건강 | Tslp 분비 저해능 및 이에 의한 알러지성 질환의 개선능을 가지는 조성물 |
| MA41912A (fr) * | 2015-04-07 | 2018-02-13 | Hyalblue S R L | Esters de glycosaminoglycane, procédés pour leur préparation et leur utilisation dans des formulations à usage ophtalmique |
| ES3040766T3 (en) * | 2018-06-29 | 2025-11-04 | Merz Pharma Gmbh & Co Kgaa | Fatty acid-grafted hyaluronic acid, dermal filler formulations comprising same, process for preparation and use thereof |
| CN109833292A (zh) * | 2019-02-23 | 2019-06-04 | 河南省人民医院 | 一种双醋瑞因滴眼液及其用途 |
| CN112138169A (zh) * | 2020-09-14 | 2020-12-29 | 广东药科大学 | 天然多糖在增加难溶性药物溶解度中的应用 |
| WO2025173034A1 (en) * | 2024-02-14 | 2025-08-21 | Zydus Lifesciences Limited | Hyaluronic acid derivatives and their therapeutic use |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4788187A (en) * | 1983-04-29 | 1988-11-29 | Rorer Pharmaceutical Corporation | Benzocyclobutene aminoalkylene ethers and thioethers, pharmaceutical composition and use |
| DE4120990C2 (de) * | 1991-06-25 | 1995-07-27 | Madaus Ag | Verfahren zur Herstellung von Diacetylrhein |
| CZ26693A3 (en) * | 1992-02-28 | 1993-12-15 | Lilly Industries Ltd | Pharmaceutical compositions |
| US5573934A (en) * | 1992-04-20 | 1996-11-12 | Board Of Regents, The University Of Texas System | Gels for encapsulation of biological materials |
| ZA936692B (en) * | 1992-09-12 | 1994-04-29 | Dott Ltd Comp | Physiologically active peptide composition |
| CA2094203A1 (en) * | 1993-04-16 | 1994-10-17 | Derek A. Willoughby | Inhibition of angiogenesis |
| US5612321A (en) * | 1995-06-22 | 1997-03-18 | Hercules Incorporated | Antioxidant grafted polysaccharides |
| FR2751615B1 (fr) * | 1996-07-23 | 1998-09-18 | Otor Sa | Plateau et flan en matiere en feuille de carton |
| JP3322203B2 (ja) * | 1997-01-31 | 2002-09-09 | 田辺製薬株式会社 | 医薬組成物 |
| CA2332802A1 (en) * | 1998-05-20 | 1999-11-25 | Chugai Seiyaku Kabushiki Kaisha | Conjugate of therapeutic agent for joint disease and hyaluronic acid |
| ITMI20022745A1 (it) * | 2002-12-23 | 2004-06-24 | Coimex Scrl United Companies | Esteri misti dell'acido ialuronico ad attivita' citostatica e prodifferenziante e procedimento per la loro produzione. |
-
2004
- 2004-02-26 IT IT000347A patent/ITMI20040347A1/it unknown
-
2005
- 2005-02-25 BR BRPI0507622A patent/BRPI0507622B8/pt not_active IP Right Cessation
- 2005-02-25 RU RU2006134015/04A patent/RU2383554C2/ru active
- 2005-02-25 US US10/590,625 patent/US7834173B2/en not_active Expired - Fee Related
- 2005-02-25 PL PL05708619T patent/PL1718679T3/pl unknown
- 2005-02-25 EP EP05708619A patent/EP1718679B1/de not_active Expired - Lifetime
- 2005-02-25 CA CA2556942A patent/CA2556942C/en not_active Expired - Fee Related
- 2005-02-25 ES ES05708619T patent/ES2293538T3/es not_active Expired - Lifetime
- 2005-02-25 JP JP2007500318A patent/JP4870068B2/ja not_active Expired - Fee Related
- 2005-02-25 WO PCT/IB2005/000506 patent/WO2005085293A1/en not_active Ceased
- 2005-02-25 PT PT05708619T patent/PT1718679E/pt unknown
- 2005-02-25 DE DE602005002538T patent/DE602005002538T2/de not_active Expired - Lifetime
- 2005-02-25 UA UAA200609263A patent/UA91673C2/ru unknown
- 2005-02-25 SI SI200530094T patent/SI1718679T1/sl unknown
- 2005-02-25 CN CNB2005800036341A patent/CN100551932C/zh not_active Expired - Fee Related
- 2005-02-25 AT AT05708619T patent/ATE373681T1/de active
-
2006
- 2006-07-25 IL IL177072A patent/IL177072A/en active IP Right Grant
-
2011
- 2011-07-21 JP JP2011160091A patent/JP2011252153A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| DE602005002538D1 (de) | 2007-10-31 |
| US7834173B2 (en) | 2010-11-16 |
| HK1099032A1 (zh) | 2007-08-03 |
| JP2011252153A (ja) | 2011-12-15 |
| ITMI20040347A1 (it) | 2004-05-26 |
| CA2556942A1 (en) | 2005-09-15 |
| WO2005085293A1 (en) | 2005-09-15 |
| JP4870068B2 (ja) | 2012-02-08 |
| DE602005002538T2 (de) | 2008-06-19 |
| PL1718679T3 (pl) | 2008-01-31 |
| BRPI0507622A (pt) | 2007-07-03 |
| BRPI0507622B8 (pt) | 2021-05-25 |
| UA91673C2 (ru) | 2010-08-25 |
| US20070203094A1 (en) | 2007-08-30 |
| BRPI0507622B1 (pt) | 2018-07-17 |
| PT1718679E (pt) | 2007-11-27 |
| ES2293538T3 (es) | 2008-03-16 |
| CA2556942C (en) | 2012-05-29 |
| IL177072A0 (en) | 2006-12-10 |
| IL177072A (en) | 2011-02-28 |
| SI1718679T1 (sl) | 2008-02-29 |
| RU2006134015A (ru) | 2008-04-10 |
| RU2383554C2 (ru) | 2010-03-10 |
| EP1718679A1 (de) | 2006-11-08 |
| EP1718679B1 (de) | 2007-09-19 |
| CN100551932C (zh) | 2009-10-21 |
| JP2007524753A (ja) | 2007-08-30 |
| CN1914228A (zh) | 2007-02-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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