ATE370144T1 - Anti apoptosis wirkstoffe - Google Patents

Anti apoptosis wirkstoffe

Info

Publication number
ATE370144T1
ATE370144T1 AT99923961T AT99923961T ATE370144T1 AT E370144 T1 ATE370144 T1 AT E370144T1 AT 99923961 T AT99923961 T AT 99923961T AT 99923961 T AT99923961 T AT 99923961T AT E370144 T1 ATE370144 T1 AT E370144T1
Authority
AT
Austria
Prior art keywords
inhibition
those
requiring
general formula
ch2oh
Prior art date
Application number
AT99923961T
Other languages
English (en)
Inventor
Tatsuji Enoki
Jun Tomono
Nobuto Koyama
Katsushige Ikai
Hiroaki Sagawa
Ikunoshin Kato
Original Assignee
Takara Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takara Bio Inc filed Critical Takara Bio Inc
Application granted granted Critical
Publication of ATE370144T1 publication Critical patent/ATE370144T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
    • A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
    • A23L3/3463—Organic compounds; Microorganisms; Enzymes
    • A23L3/3535—Organic compounds containing sulfur
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
    • A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
    • A23L3/3463—Organic compounds; Microorganisms; Enzymes
    • A23L3/3562—Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
AT99923961T 1998-06-09 1999-06-08 Anti apoptosis wirkstoffe ATE370144T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP17529598 1998-06-09
JP22372398 1998-07-24
JP1163999 1999-01-20

Publications (1)

Publication Number Publication Date
ATE370144T1 true ATE370144T1 (de) 2007-09-15

Family

ID=27279509

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99923961T ATE370144T1 (de) 1998-06-09 1999-06-08 Anti apoptosis wirkstoffe

Country Status (11)

Country Link
US (1) US6531148B1 (de)
EP (1) EP1086952B1 (de)
JP (2) JP3779153B2 (de)
KR (3) KR100696404B1 (de)
CN (1) CN1131867C (de)
AT (1) ATE370144T1 (de)
AU (1) AU764582B2 (de)
CA (1) CA2334249A1 (de)
DE (1) DE69936855T2 (de)
TW (1) TWI244484B (de)
WO (1) WO1999064424A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001181191A (ja) * 1999-12-24 2001-07-03 Cci Corp 慢性関節リウマチ疾患予防および治療剤
AU2001225484A1 (en) * 2000-01-13 2001-07-24 Takara Bio Inc. Agents correcting gene expression regulatory error
US20040081618A1 (en) * 2000-10-03 2004-04-29 Tatsuji Enoki Method of screening physiologically active substance
KR100373776B1 (ko) * 2000-12-27 2003-02-26 한불화장품주식회사 화장료 조성물
CH692180A5 (it) * 2001-06-22 2002-03-15 Gecomwert Anstalt Preparato cosmetico con azione antirughe.
WO2003024446A1 (fr) * 2001-09-11 2003-03-27 Mitsubishi Pharma Corporation Inhibiteur du stress oxydatif et methode de mesure du stress oxydatif
US20050063995A1 (en) * 2001-10-25 2005-03-24 Spaner David E Compositions and methods for selected tumour treatment
US20050124575A1 (en) * 2002-04-17 2005-06-09 Takara Bio Inc. Remedies
BRPI0610945B1 (pt) * 2005-05-31 2016-09-20 Arla Foods Amba Processo para a preparação de uma fonte de fosfatidilserina derivada de leite bovino, fonte e composição nutracêutica compreendendo a mesma”
WO2012148023A1 (ko) * 2011-04-29 2012-11-01 바이올시스템즈 주식회사 무수갈락토스의 분리정제 방법
CN102321153B (zh) * 2011-09-06 2013-06-05 中国科学院成都生物研究所 一种新奥苷肽粉状固体的制备方法
CN111544437A (zh) * 2012-01-18 2020-08-18 高丽大学校产学协力团 3,6-脱水-l-半乳糖的制备方法及其用途
JP6241644B2 (ja) * 2013-06-05 2017-12-06 伊那食品工業株式会社 ＰＰＡＲγ発現向上剤、並びにそれを含む基礎代謝向上剤、筋肉疲労回復向上剤、ＰＰＡＲγ発現向上用医薬組成物及びＰＰＡＲγ発現向上用飲食品
KR102011721B1 (ko) * 2017-11-28 2019-08-19 고려대학교 산학협력단 포도상구균의 생육을 억제하는 한천 유래 올리고당의 용도
CN108776121B (zh) * 2018-04-08 2021-07-30 广州卡马生物科技有限公司 一种基于荧光猝灭原理对药材中抗氧剂的高通量筛选方法
CN112375110A (zh) * 2020-11-20 2021-02-19 西安乐析医疗科技有限公司 一种化合物3,4-dge的制备方法
KR102608602B1 (ko) * 2020-11-27 2023-12-01 (주)헬스코치생명공학 Ahg를 이용한 자외선에 의한 피부 주름 개선용 조성물

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1202286B (de) * 1962-08-04 1965-10-07 Huels Chemische Werke Ag Verfahren zur Herstellung von beta-Pyronen
US3230233A (en) * 1964-03-04 1966-01-18 American Cyanamid Co Novel substituted 2, 3-dihydro-9-carbamo-yloxymethyl-6-methyl-pyrrolo[1, 2-a] indole-5, 8-diones
FR2541307A1 (fr) * 1983-02-23 1984-08-24 Korano Substance gelifiante semi-synthetique, son procede de preparation et ses applications, notamment dans les milieux de culture pour microorganismes
JPS62210958A (ja) * 1986-03-13 1987-09-17 Meiji Seika Kaisha Ltd 澱粉含有組成物の老化防止方法
JPH04316593A (ja) * 1991-02-21 1992-11-06 Japan Tobacco Inc Ｄ−アロサンの製造方法
JPH05565A (ja) * 1991-06-21 1993-01-08 Toyo Ink Mfg Co Ltd 皮膜形成方法
US5380834A (en) * 1992-02-06 1995-01-10 Ishihara Sangyo Kaisha Ltd. Immuno-suppressive agent
EP0570252A3 (en) * 1992-05-15 1994-02-23 Ina Food Ind Co Ltd Low gel strength agar-agar
CA2121148A1 (en) * 1992-08-19 1994-03-03 Satoru Nakai Apoptosis regulator
JP3193480B2 (ja) * 1992-09-03 2001-07-30 石原産業株式会社 免疫機能抑制剤
JP3266343B2 (ja) * 1992-12-17 2002-03-18 芝浦メカトロニクス株式会社 クリームはんだ印刷装置
JP3865801B2 (ja) * 1995-04-27 2007-01-10 株式会社ヤクルト本社 新規なβ−アガラーゼ，その製造方法及びその用途
US5834257A (en) * 1995-11-06 1998-11-10 Japan Tobacco Inc. α-agarase and production process of oligosaccharides and monosaccharides
WO1998020884A1 (fr) * 1996-11-08 1998-05-22 Takara Shuzo Co., Ltd. Inducteurs d'apoptose
AU1890399A (en) * 1998-01-19 1999-08-02 Takara Shuzo Co., Ltd. Substances capable of inducing apoptosis

Also Published As

Publication number Publication date
AU4060699A (en) 1999-12-30
TWI244484B (en) 2005-12-01
WO1999064424A8 (fr) 2000-04-06
CN1131867C (zh) 2003-12-24
WO1999064424A1 (fr) 1999-12-16
DE69936855T2 (de) 2008-05-15
JP2006117662A (ja) 2006-05-11
EP1086952A4 (de) 2005-02-02
CA2334249A1 (en) 1999-12-16
KR20060086454A (ko) 2006-07-31
EP1086952A1 (de) 2001-03-28
KR100735139B1 (ko) 2007-07-03
KR20060116034A (ko) 2006-11-13
EP1086952B1 (de) 2007-08-15
JP3779153B2 (ja) 2006-05-24
KR20010025107A (ko) 2001-03-26
DE69936855D1 (de) 2007-09-27
KR100620409B1 (ko) 2006-09-13
CN1312813A (zh) 2001-09-12
KR100696404B1 (ko) 2007-03-20
AU764582B2 (en) 2003-08-21
US6531148B1 (en) 2003-03-11

Similar Documents

Publication Publication Date Title
ATE370144T1 (de) Anti apoptosis wirkstoffe
ATE210650T1 (de) Sulfonamid substituierte benzopyrane als kaliumkanalaktivatoren
CA2335285A1 (en) Bicyclic piperidine and piperazine compounds having 5-ht6 receptor affinity
HUT59109A (en) Process for producing hydroxymethyl-(methylenecyclopentyl)-purines and -pyrimidines, their pharmaceutically acceptable salts and pharmaceutical compositions comprising same
TR200800474T2 (tr) Florfenikole aracı maddelerin hazırlanmasına ilişkin işlem.
EP0902007A4 (de) Chalcon-derivate und medikamente die diese enthalten
ATE210635T1 (de) Aromatische hydroxamsäure-verbindungen, ihre herstellung und verwendung
EP1652847A3 (de) Chinolin- und Chianzolinderivate zur Behandlung von Tumoren
GR3020929T3 (en) Tricyclic compounds
ES2191260T3 (es) Derivados de la imidazolidin-4-ona utiles como agentes anticancerosos.
ATE227293T1 (de) 2,3-disubstituierte-(5,6)-heteroarylkondensiert - pyrimidin-4-one
CA2037975A1 (en) 5-hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors
DK656789D0 (da) Benzoheterocykliske forbindelser
EP1094055A4 (de) Neue vinylbenzolderivate
EP1043310A4 (de) Biphenylamidin-derivate
MX9202975A (es) Nuevos compuestos biciclicos y sus sales farmaceuticamente aceptables y procedimiento para su preparacion.
HK1015766A1 (en) 1-methylcarbapenem derivatives
EP1152004A4 (de) Derivate der phosphonsäure zur inhibierung von carboxypeptidase b
DE60016908D1 (de) Verwendung von Sulfoquinovosyldiacylglycerol Derivativen als Immunosuppresssiva
WO2000027378A3 (en) Cystine derivatives as therapeutic agents for matrix metalloprotease related diseases
HUT75124A (en) Use of bicyclolactam derivatives for producing pharmaceutical compositions having anxiolytic activity
AU6509190A (en) Fungicidal 3-imino-1,4-oxathiins
HK54891A (en) Hexahydropyrrolo(2,1-a)isoquinoline derivatives
AU7020996A (en) UCK14 compounds
ATE258934T1 (de) Azaindol derivate und ihre verwendung als antithrombotische wirkstoffe

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties