DE69936855D1 - Anti Apoptosis Wirkstoffe - Google Patents
Anti Apoptosis WirkstoffeInfo
- Publication number
- DE69936855D1 DE69936855D1 DE69936855T DE69936855T DE69936855D1 DE 69936855 D1 DE69936855 D1 DE 69936855D1 DE 69936855 T DE69936855 T DE 69936855T DE 69936855 T DE69936855 T DE 69936855T DE 69936855 D1 DE69936855 D1 DE 69936855D1
- Authority
- DE
- Germany
- Prior art keywords
- inhibition
- those
- requiring
- general formula
- ch2oh
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000006909 anti-apoptosis Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 230000005764 inhibitory process Effects 0.000 abstract 5
- 201000010099 disease Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 3
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 abstract 2
- 230000006698 induction Effects 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 102000002812 Heat-Shock Proteins Human genes 0.000 abstract 1
- 108010004889 Heat-Shock Proteins Proteins 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000006907 apoptotic process Effects 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
- 210000002437 synoviocyte Anatomy 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000014616 translation Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
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- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/3535—Organic compounds containing sulfur
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- A—HUMAN NECESSITIES
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- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/3562—Sugars; Derivatives thereof
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- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
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- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Mycology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17529598 | 1998-06-09 | ||
JP17529598 | 1998-06-09 | ||
JP22372398 | 1998-07-24 | ||
JP22372398 | 1998-07-24 | ||
JP1163999 | 1999-01-20 | ||
JP1163999 | 1999-01-20 | ||
PCT/JP1999/003058 WO1999064424A1 (fr) | 1998-06-09 | 1999-06-08 | Agents therapeutiques |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69936855D1 true DE69936855D1 (de) | 2007-09-27 |
DE69936855T2 DE69936855T2 (de) | 2008-05-15 |
Family
ID=27279509
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69936855T Expired - Fee Related DE69936855T2 (de) | 1998-06-09 | 1999-06-08 | Anti Apoptosis Wirkstoffe |
Country Status (11)
Country | Link |
---|---|
US (1) | US6531148B1 (de) |
EP (1) | EP1086952B1 (de) |
JP (2) | JP3779153B2 (de) |
KR (3) | KR100620409B1 (de) |
CN (1) | CN1131867C (de) |
AT (1) | ATE370144T1 (de) |
AU (1) | AU764582B2 (de) |
CA (1) | CA2334249A1 (de) |
DE (1) | DE69936855T2 (de) |
TW (1) | TWI244484B (de) |
WO (1) | WO1999064424A1 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001181191A (ja) * | 1999-12-24 | 2001-07-03 | Cci Corp | 慢性関節リウマチ疾患予防および治療剤 |
AU2001225484A1 (en) * | 2000-01-13 | 2001-07-24 | Takara Bio Inc. | Agents correcting gene expression regulatory error |
EP1329516A4 (de) * | 2000-10-03 | 2004-11-17 | Takara Bio Inc | Verfahren zum screening einer physiologisch aktiven substanz |
KR100373776B1 (ko) * | 2000-12-27 | 2003-02-26 | 한불화장품주식회사 | 화장료 조성물 |
CH692180A5 (it) * | 2001-06-22 | 2002-03-15 | Gecomwert Anstalt | Preparato cosmetico con azione antirughe. |
JPWO2003024446A1 (ja) * | 2001-09-11 | 2004-12-24 | 三菱ウェルファーマ株式会社 | 酸化ストレス抑制剤および酸化ストレスの測定方法 |
US20050063995A1 (en) * | 2001-10-25 | 2005-03-24 | Spaner David E | Compositions and methods for selected tumour treatment |
KR100712264B1 (ko) * | 2002-04-17 | 2007-04-27 | 다카라 바이오 가부시키가이샤 | 치료제 |
DK1901620T3 (da) * | 2005-05-31 | 2020-09-28 | Arla Foods Amba | Phosphatidylserin-berigede mælkefraktioner til formulering af funktionelle fødevarer |
WO2012148023A1 (ko) * | 2011-04-29 | 2012-11-01 | 바이올시스템즈 주식회사 | 무수갈락토스의 분리정제 방법 |
CN102321153B (zh) * | 2011-09-06 | 2013-06-05 | 中国科学院成都生物研究所 | 一种新奥苷肽粉状固体的制备方法 |
US20150216778A1 (en) | 2012-01-18 | 2015-08-06 | Korea University Research And Business Foundation | Method for Preparing 3,6-Anhydro-L-Galactose, And Use Thereof |
JP6241644B2 (ja) * | 2013-06-05 | 2017-12-06 | 伊那食品工業株式会社 | PPARγ発現向上剤、並びにそれを含む基礎代謝向上剤、筋肉疲労回復向上剤、PPARγ発現向上用医薬組成物及びPPARγ発現向上用飲食品 |
KR102011721B1 (ko) * | 2017-11-28 | 2019-08-19 | 고려대학교 산학협력단 | 포도상구균의 생육을 억제하는 한천 유래 올리고당의 용도 |
CN108776121B (zh) * | 2018-04-08 | 2021-07-30 | 广州卡马生物科技有限公司 | 一种基于荧光猝灭原理对药材中抗氧剂的高通量筛选方法 |
CN112375110A (zh) * | 2020-11-20 | 2021-02-19 | 西安乐析医疗科技有限公司 | 一种化合物3,4-dge的制备方法 |
KR102608602B1 (ko) * | 2020-11-27 | 2023-12-01 | (주)헬스코치생명공학 | Ahg를 이용한 자외선에 의한 피부 주름 개선용 조성물 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1202286B (de) * | 1962-08-04 | 1965-10-07 | Huels Chemische Werke Ag | Verfahren zur Herstellung von beta-Pyronen |
US3230233A (en) * | 1964-03-04 | 1966-01-18 | American Cyanamid Co | Novel substituted 2, 3-dihydro-9-carbamo-yloxymethyl-6-methyl-pyrrolo[1, 2-a] indole-5, 8-diones |
FR2541307A1 (fr) * | 1983-02-23 | 1984-08-24 | Korano | Substance gelifiante semi-synthetique, son procede de preparation et ses applications, notamment dans les milieux de culture pour microorganismes |
JPS62210958A (ja) * | 1986-03-13 | 1987-09-17 | Meiji Seika Kaisha Ltd | 澱粉含有組成物の老化防止方法 |
JPH04316593A (ja) * | 1991-02-21 | 1992-11-06 | Japan Tobacco Inc | D−アロサンの製造方法 |
JPH05565A (ja) * | 1991-06-21 | 1993-01-08 | Toyo Ink Mfg Co Ltd | 皮膜形成方法 |
US5380834A (en) * | 1992-02-06 | 1995-01-10 | Ishihara Sangyo Kaisha Ltd. | Immuno-suppressive agent |
EP0570252A3 (en) * | 1992-05-15 | 1994-02-23 | Ina Food Ind Co Ltd | Low gel strength agar-agar |
CA2121148A1 (en) * | 1992-08-19 | 1994-03-03 | Satoru Nakai | Apoptosis regulator |
JP3193480B2 (ja) * | 1992-09-03 | 2001-07-30 | 石原産業株式会社 | 免疫機能抑制剤 |
JP3266343B2 (ja) | 1992-12-17 | 2002-03-18 | 芝浦メカトロニクス株式会社 | クリームはんだ印刷装置 |
JP3865801B2 (ja) * | 1995-04-27 | 2007-01-10 | 株式会社ヤクルト本社 | 新規なβ−アガラーゼ,その製造方法及びその用途 |
US5834257A (en) * | 1995-11-06 | 1998-11-10 | Japan Tobacco Inc. | α-agarase and production process of oligosaccharides and monosaccharides |
WO1998020884A1 (fr) * | 1996-11-08 | 1998-05-22 | Takara Shuzo Co., Ltd. | Inducteurs d'apoptose |
DE69926994T2 (de) * | 1998-01-19 | 2006-06-22 | Takara Bio Inc., Otsu | Substanzen, welche apoptose einleiten können |
-
1999
- 1999-06-07 TW TW088109429A patent/TWI244484B/zh active
- 1999-06-08 US US09/719,314 patent/US6531148B1/en not_active Expired - Fee Related
- 1999-06-08 EP EP99923961A patent/EP1086952B1/de not_active Expired - Lifetime
- 1999-06-08 CN CN99809417XA patent/CN1131867C/zh not_active Expired - Fee Related
- 1999-06-08 AU AU40606/99A patent/AU764582B2/en not_active Ceased
- 1999-06-08 AT AT99923961T patent/ATE370144T1/de not_active IP Right Cessation
- 1999-06-08 CA CA002334249A patent/CA2334249A1/en not_active Abandoned
- 1999-06-08 KR KR1020007013293A patent/KR100620409B1/ko not_active IP Right Cessation
- 1999-06-08 DE DE69936855T patent/DE69936855T2/de not_active Expired - Fee Related
- 1999-06-08 KR KR1020067021143A patent/KR100735139B1/ko not_active IP Right Cessation
- 1999-06-08 WO PCT/JP1999/003058 patent/WO1999064424A1/ja active IP Right Grant
- 1999-06-08 JP JP2000553433A patent/JP3779153B2/ja not_active Expired - Fee Related
- 1999-06-08 KR KR1020067013109A patent/KR100696404B1/ko not_active IP Right Cessation
-
2005
- 2005-10-07 JP JP2005295271A patent/JP2006117662A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU4060699A (en) | 1999-12-30 |
AU764582B2 (en) | 2003-08-21 |
EP1086952A1 (de) | 2001-03-28 |
KR100696404B1 (ko) | 2007-03-20 |
DE69936855T2 (de) | 2008-05-15 |
CA2334249A1 (en) | 1999-12-16 |
CN1131867C (zh) | 2003-12-24 |
KR20060086454A (ko) | 2006-07-31 |
US6531148B1 (en) | 2003-03-11 |
ATE370144T1 (de) | 2007-09-15 |
WO1999064424A1 (fr) | 1999-12-16 |
JP2006117662A (ja) | 2006-05-11 |
EP1086952B1 (de) | 2007-08-15 |
TWI244484B (en) | 2005-12-01 |
EP1086952A4 (de) | 2005-02-02 |
CN1312813A (zh) | 2001-09-12 |
JP3779153B2 (ja) | 2006-05-24 |
KR100735139B1 (ko) | 2007-07-03 |
KR20010025107A (ko) | 2001-03-26 |
WO1999064424A8 (fr) | 2000-04-06 |
KR100620409B1 (ko) | 2006-09-13 |
KR20060116034A (ko) | 2006-11-13 |
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Inventor name: ENOKI, TATSUJI, OTSU-SHI SHIGA 520-0865, JP Inventor name: TOMONO, JUN, MUKO-SHI KYOTO 617-0002, JP Inventor name: KOYAMA, NOBUTO, UJI-SHI KYOTO 611-0042, JP Inventor name: IKAI, KATSUSHIGE, KOKA-GUN SHIGA 520-3332, JP Inventor name: SAGAWA, HIROAKI, OTSU-SHI SHIGA 525-0025, JP Inventor name: KATO, IKUNOSHIN, UJI-SHI KYOTO 611-0028, JP |
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