ATE366815T1 - Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand - Google Patents

Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand

Info

Publication number
ATE366815T1
ATE366815T1 AT05003040T AT05003040T ATE366815T1 AT E366815 T1 ATE366815 T1 AT E366815T1 AT 05003040 T AT05003040 T AT 05003040T AT 05003040 T AT05003040 T AT 05003040T AT E366815 T1 ATE366815 T1 AT E366815T1
Authority
AT
Austria
Prior art keywords
protein
known ligand
receptor coupled
rup3 receptor
human rup3
Prior art date
Application number
AT05003040T
Other languages
German (de)
English (en)
Inventor
Ruoping Chen
James N Leonard
Original Assignee
Arena Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arena Pharm Inc filed Critical Arena Pharm Inc
Application granted granted Critical
Publication of ATE366815T1 publication Critical patent/ATE366815T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT05003040T 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand ATE366815T1 (de)

Applications Claiming Priority (23)

Application Number Priority Date Filing Date Title
US10921398P 1998-11-20 1998-11-20
US12041699P 1999-02-16 1999-02-16
US12185299P 1999-02-26 1999-02-26
US12394699P 1999-03-12 1999-03-12
US12394999P 1999-03-12 1999-03-12
US13643799P 1999-05-28 1999-05-28
US13643699P 1999-05-28 1999-05-28
US13643999P 1999-05-28 1999-05-28
US13656799P 1999-05-28 1999-05-28
US13712799P 1999-05-28 1999-05-28
US13713199P 1999-05-28 1999-05-28
US14144899P 1999-06-29 1999-06-29
US15663499P 1999-09-29 1999-09-29
US15665399P 1999-09-29 1999-09-29
US15655599P 1999-09-29 1999-09-29
US15663399P 1999-09-29 1999-09-29
US15728099P 1999-10-01 1999-10-01
US15728199P 1999-10-01 1999-10-01
US15728299P 1999-10-01 1999-10-01
US15729499P 1999-10-01 1999-10-01
US15729399P 1999-10-01 1999-10-01
US41676099A 1999-10-12 1999-10-12
US41704499A 1999-10-12 1999-10-12

Publications (1)

Publication Number Publication Date
ATE366815T1 true ATE366815T1 (de) 2007-08-15

Family

ID=27586698

Family Applications (3)

Application Number Title Priority Date Filing Date
AT05003040T ATE366815T1 (de) 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand
AT07008841T ATE396400T1 (de) 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelte rezeptor rup3 ohne bekannte ligand
AT99972682T ATE301673T1 (de) 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand

Family Applications After (2)

Application Number Title Priority Date Filing Date
AT07008841T ATE396400T1 (de) 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelte rezeptor rup3 ohne bekannte ligand
AT99972682T ATE301673T1 (de) 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand

Country Status (12)

Country Link
EP (8) EP2295574A1 (enExample)
JP (5) JP2003534767A (enExample)
KR (5) KR100963367B1 (enExample)
AT (3) ATE366815T1 (enExample)
AU (2) AU770056B2 (enExample)
CA (2) CA2645717A1 (enExample)
DK (3) DK1133559T3 (enExample)
ES (3) ES2289610T3 (enExample)
IL (2) IL142538A0 (enExample)
NZ (3) NZ511087A (enExample)
PT (3) PT1584683E (enExample)
WO (1) WO2000031258A2 (enExample)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1690939B8 (en) 1998-03-12 2010-10-13 Astellas Pharma Inc. Novel G protein-coupled receptor proteins
JP2002512780A (ja) * 1998-04-24 2002-05-08 スミスクライン ビーチャム コーポレーション 新規７ｔｍ受容体ａｘｏｒ−２のクローニング
US6071722A (en) * 1998-04-24 2000-06-06 Smithkline Beecham Corporation Nucleic acids encoding a G-protein coupled 7TM receptor (AXOR-1)
WO2000026339A2 (en) * 1998-11-03 2000-05-11 Smithkline Beecham Corporation Axor14, a g-protein coupled receptor
US7816492B2 (en) 1998-11-20 2010-10-19 Arena Pharmaceuticals, Inc. Human G protein-coupled receptors
USRE42190E1 (en) 1998-11-20 2011-03-01 Arena Pharmaceuticals, Inc. Method of identifying a compound for inhibiting or stimulating human G protein-coupled receptors
US20030017528A1 (en) 1998-11-20 2003-01-23 Ruoping Chen Human orphan G protein-coupled receptors
US6221660B1 (en) 1999-02-22 2001-04-24 Synaptic Pharmaceutical Corporation DNA encoding SNORF25 receptor
WO2000050458A1 (en) * 1999-02-26 2000-08-31 Smithkline Beecham Corporation Cloning of a p2y-like 7tm receptor (axor17)
US6620615B1 (en) * 1999-04-23 2003-09-16 Curagen Corporation G-protein coupled receptor—encoding nucleic acids
EP1189944A4 (en) * 1999-06-21 2002-09-11 Smithkline Beecham Corp AXOR16, R CEPTEUR COUPL UNE PROT INE G
JP2003504054A (ja) * 1999-07-13 2003-02-04 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング Ｇ−タンパク質共役型受容体およびそのｄｎａ配列
EP1198569A1 (en) * 1999-07-30 2002-04-24 MERCK PATENT GmbH G-protein coupled receptor and dna sequences thereof
WO2001016179A1 (fr) * 1999-08-27 2001-03-08 Takeda Chemical Industries, Ltd. Nouvelle proteine receptrice couplee a une proteine g, et son adn
US6998255B1 (en) 1999-09-24 2006-02-14 Solvay Pharmaceuticals B.V. Human G-protein coupled receptor
GB9923177D0 (en) * 1999-09-30 1999-12-01 Pfizer Ltd Novel polypeptide
US6204017B1 (en) 1999-10-07 2001-03-20 Schering Corporation Polynucleotide encoding a histamine receptor
GB9923890D0 (en) * 1999-10-08 1999-12-08 Pfizer Ltd Novel polypeptide
GB9923893D0 (en) * 1999-10-08 1999-12-08 Pfizer Ltd Novel polypeptide
GB9924956D0 (en) * 1999-10-21 1999-12-22 Pfizer Ltd Novel polypeptide
GB9924960D0 (en) * 1999-10-21 1999-12-22 Pfizer Ltd Novel polypeptide
WO2001031014A2 (en) * 1999-10-27 2001-05-03 Pharmacia & Upjohn Company G protein-coupled receptors expressed in human brain
ATE375390T1 (de) * 1999-10-29 2007-10-15 Pfizer G-protein-gekoppelter rezeptor-ähnliche proteine
EP1226250A2 (en) * 1999-11-03 2002-07-31 MERCK PATENT GmbH Gpcr-kd5 polypeptides and dna sequences thereof
US6461836B1 (en) 1999-11-05 2002-10-08 Smithkline Beecham Corporation Molecular cloning of a 7TM receptor (AxOR34) and screening methods thereof
EP1237909A2 (en) * 1999-11-16 2002-09-11 PHARMACIA & UPJOHN COMPANY Human g protein-coupled receptors
US7029857B1 (en) 1999-12-17 2006-04-18 H. Lundbeck A/S Processes for obtaining compounds employing SNORF72 receptors
WO2001046414A1 (fr) * 1999-12-20 2001-06-28 Banyu Pharmaceutical Co., Ltd. Nouvelle proteine receptrice couplee a la proteine de fixation de guanosine triphosphate, bg26
AU2288601A (en) 1999-12-23 2001-07-03 Millennium Pharmaceuticals, Inc. P2Y12 receptor
WO2001048189A1 (fr) * 1999-12-28 2001-07-05 Helix Research Institute Nouveaux recepteurs couples a une proteine de liaison au guanosine triphosphate, genes de ces derniers, et production et utilisation de ces derniers
GB0001700D0 (en) * 2000-01-25 2000-03-15 Glaxo Group Ltd Novel protein
DE60129933T2 (de) 2000-02-04 2008-02-14 Takeda Pharmaceutical Co. Ltd. Verfahren zum screening
ATE356208T1 (de) * 2000-03-14 2007-03-15 Bayer Healthcare Ag Regulation des menschliches lipoxin a4 rezeptor- ähnliches protein
EP1268777A2 (en) * 2000-03-17 2003-01-02 Bayer Aktiengesellschaft Regulation of human leukotriene b 4?-like g protein-coupled receptor
EP1270589A4 (en) * 2000-03-21 2004-09-29 Yamanouchi Pharma Co Ltd NEW LEUKOTRIENB4 RECEPTOR
WO2001073021A1 (fr) * 2000-03-28 2001-10-04 Takeda Chemical Industries, Ltd. Nouvelle proteine receptrice couplee a une proteine g et adn associe
AU4467301A (en) * 2000-03-31 2001-10-08 Helix Research Institute Novel guanosine triphosphate-binding protein-coupled receptor gprv53, gene thereof and production and use of the same
WO2001077326A1 (fr) * 2000-04-12 2001-10-18 Takeda Chemical Industries, Ltd. Proteine receptrice couplee a la proteine g et son adn
EP1178110A1 (en) * 2000-08-01 2002-02-06 Aventis Pharma Deutschland GmbH EDG8 receptor for sphingosine 1-phosphate , its preparation and use
EP1287133B1 (en) * 2000-05-18 2006-12-13 Bayer HealthCare AG Regulation of human dopamine-like g protein-coupled receptor
WO2002000719A2 (en) * 2000-06-23 2002-01-03 Tularik Inc. Human and mouse g-protein couipled receptors
JP2004501629A (ja) * 2000-06-26 2004-01-22 アクゾ・ノベル・エヌ・ベー Ｇタンパク質共役受容体ｏｒｇ１０
WO2002002599A2 (en) * 2000-06-30 2002-01-10 Ingenium Pharmaceuticals Ag HUMAN G PROTEIN-COUPLED RECEPTOR IGPcR17, AND USES THEROF
WO2002004518A2 (en) * 2000-07-06 2002-01-17 Bayer Corporation Human neuropeptide y-like g protein-coupled receptor
EP1311546A2 (en) * 2000-08-09 2003-05-21 Millenium Pharmaceuticals, Inc. Methods for using 14266, a human g protein-coupled receptor
US6790608B2 (en) * 2000-09-20 2004-09-14 The Regents Of The University Of California Methods of identifying and ADP-glucose receptor ligand, agonist or antagonist
AU2002210982A1 (en) 2000-11-01 2002-05-15 Yamanouchi Pharmaceutical Co..Ltd. Method of screening antiplatelet
JP4178028B2 (ja) * 2000-11-07 2008-11-12 タケダ ケンブリッジ リミテッド 受容体
WO2002042461A2 (en) * 2000-11-27 2002-05-30 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors
US20030180813A1 (en) 2000-12-01 2003-09-25 Takahide Ohishi Method of screening remedy for diabetes
WO2002052047A2 (en) * 2000-12-22 2002-07-04 Mergen Ltd. Methods for identifying g-protein coupled receptors associated with diseases
US7220580B2 (en) 2000-12-22 2007-05-22 University Of South Florida Sphingosine 1-phosphate receptor gene, sppr
GB0100782D0 (en) * 2001-01-11 2001-02-21 Glaxo Group Ltd Assay
EP1382678B1 (en) * 2001-04-25 2008-08-27 Astellas Pharma Inc. Guanosine triphosphate-binding protein-coupled recepotr place 6002312 and its gene and production and use of the same
US20030096299A1 (en) 2001-07-09 2003-05-22 Valerie Wittamer Natural ligand of G protein coupled receptor ChemR23 and uses thereof
US7419658B2 (en) 2001-07-09 2008-09-02 Euroscreen S.A. Isolated ligand of ChemerinR
US7858755B2 (en) 2001-07-09 2010-12-28 Euroscreen S.A. Monoclonal antibodies that bind Chemerin polypeptide
US6946244B2 (en) * 2001-08-07 2005-09-20 Euroscreen, S.A. Methods of identifying a ligand, an agonist, and an antagonist of G protein coupled receptor GPR86 (P2Y13)
MXPA04009959A (es) 2002-04-12 2004-12-13 Schering Corp Ligandos del receptor acoplado a la proteina g y metodos.
AU2003261874A1 (en) * 2002-09-02 2004-03-29 Takeda Pharmaceutical Company Limited Adrenocortical hormone secretion controller
JPWO2004033687A1 (ja) * 2002-10-11 2006-02-09 アステラス製薬株式会社 腎不全治療薬をスクリーニングする方法
US7056685B1 (en) 2002-11-05 2006-06-06 Amgen Inc. Receptor ligands and methods of modulating receptors
JP4516430B2 (ja) 2002-12-20 2010-08-04 メルク・シャープ・エンド・ドーム・コーポレイション １−（アミノ）インダン並びに（１，２−ジヒドロ−３−アミノ）−ベンゾフラン、ベンゾチオフェン及びインドール
GEP20084540B (en) 2003-01-14 2008-11-25 Arena Pharm Inc 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prpphylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
US7083933B1 (en) 2003-05-09 2006-08-01 Prosidion Limited Methods for identification of modulators of OSGPR116 activity
EP1648488A4 (en) * 2003-06-27 2007-01-24 Tanox Inc MEMBRANE PROTEIN EXPRESSED IN HUMAN MASTOCYTES
US7524638B1 (en) 2003-06-27 2009-04-28 Osi Pharmaceuticals, Inc. Methods for identification of modulators of OSGPR114 or OSGPR78 activity, and their use in the treatment of disease
DOP2006000008A (es) 2005-01-10 2006-08-31 Arena Pharm Inc Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1
GB0508990D0 (en) * 2005-05-03 2005-06-08 Novartis Ag Organic compounds
EP2410330A3 (en) 2006-04-11 2012-06-13 Arena Pharmaceuticals, Inc. Methods of using GPR119 receptor to identify compounds useful for increasing bone mass in an individual
US7638541B2 (en) 2006-12-28 2009-12-29 Metabolex Inc. 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine
JP5489997B2 (ja) 2007-07-19 2014-05-14 シマベイ セラピューティクス， インコーポレーテッド 糖尿病および代謝疾患の治療のためのＲＵＰ３またはＧＰＲｌ１９受容体のアゴニストとしてのＮ−アザ環状置換ピロール、ピラゾール、イミダゾール、トリアゾールおよびテトラゾール誘導体
EP2197873B1 (en) 2007-09-20 2014-07-16 Irm Llc Compounds and compositions as modulators of gpr119 activity
EP2108960A1 (en) 2008-04-07 2009-10-14 Arena Pharmaceuticals, Inc. Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditons modulated by PYY
AR077642A1 (es) 2009-07-09 2011-09-14 Arena Pharm Inc Moduladores del metabolismo y el tratamiento de trastornos relacionados con el mismo
ES2497566T3 (es) 2009-10-01 2014-09-23 Cymabay Therapeutics, Inc. Sales de tetrazol-1-il-fenoximetil-tiazol-2-il-piperidinil-pirimidina sustituida
US8791100B2 (en) 2010-02-02 2014-07-29 Novartis Ag Aryl benzylamine compounds
US20130023494A1 (en) 2010-04-06 2013-01-24 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
CN109674753A (zh) 2010-06-23 2019-04-26 希玛贝治疗股份有限公司 固态分散体
JP5941916B2 (ja) 2010-09-22 2016-06-29 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｇｐｒ１１９レセプターのモジュレーターおよびそれに関連する障害の処置
US20140018371A1 (en) 2011-04-01 2014-01-16 Arena Pharmaceuticals, Inc. Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
US20140066369A1 (en) 2011-04-19 2014-03-06 Arena Pharmaceuticals, Inc. Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
US20140051714A1 (en) 2011-04-22 2014-02-20 Arena Pharmaceuticals, Inc. Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
US20140038889A1 (en) 2011-04-22 2014-02-06 Arena Pharmaceuticals, Inc. Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
WO2012170702A1 (en) 2011-06-08 2012-12-13 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2013055910A1 (en) 2011-10-12 2013-04-18 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2014074668A1 (en) 2012-11-08 2014-05-15 Arena Pharmaceuticals, Inc. Modulators of gpr119 and the treatment of disorders related thereto
DK3242666T5 (da) 2015-01-06 2025-01-20 Arena Pharm Inc Forbindelsee til anvendelse i behandling af tilstande, der er forbundet med SIP1-receptoren
JP6838744B2 (ja) 2015-06-22 2021-03-03 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｓ１Ｐ１レセプター関連障害における使用のための（Ｒ）−２−（７−（４−シクロペンチル−３−（トリフルオロメチル）ベンジルオキシ）−１，２，３，４−テトラヒドロシクロペンタ［ｂ］インドール−３−イル）酢酸（化合物１）の結晶性Ｌ−アルギニン塩
US10292983B2 (en) 2016-08-03 2019-05-21 Cymabay Therapeutics, Inc. Oxymethylene aryl compounds for treating inflammatory gastrointestinal diseases or gastrointestinal conditions
WO2018236896A1 (en) 2017-06-19 2018-12-27 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of nafld and nash
ES2987794T3 (es) 2018-06-06 2024-11-18 Arena Pharm Inc Procedimientos de tratamiento de afecciones relacionadas con el receptor S1P1

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0868510A2 (en) * 1995-11-15 1998-10-07 Cor Therapeutics, Inc. P2u2 PURINERGIC RECEPTOR
EP0955808A1 (en) * 1996-01-11 1999-11-17 Human Genome Sciences, Inc. Human g-protein coupled receptor
AU6017098A (en) * 1997-01-21 1998-08-07 Schering Corporation Mammalian chemokines; receptors; reagents; uses
US6221627B1 (en) * 1997-02-24 2001-04-24 Smithkline Beecham Corporation cDNA clone HDPB130 that encodes a novel human 7-transmembrane receptor
US5955303A (en) * 1997-03-06 1999-09-21 Incyte Pharmaceuticals, Inc. Human chemokine receptor-like protein
US6555339B1 (en) * 1997-04-14 2003-04-29 Arena Pharmaceuticals, Inc. Non-endogenous, constitutively activated human protein-coupled receptors
US6060272A (en) * 1997-05-07 2000-05-09 Human Genome Sciences, Inc. Human G-protein coupled receptors
EP0899332A3 (en) * 1997-08-15 2000-07-05 Smithkline Beecham Corporation The G-protein coupled receptor HFIAO41
CA2239255A1 (en) * 1997-10-23 1999-04-23 Smithkline Beecham Corporation Cdna clone hneaa81 that encodes a human 7-transmembrane receptor
US5932445A (en) * 1997-11-07 1999-08-03 Incyte Pharmaceuticals, Inc. Signal peptide-containing proteins
US6252056B1 (en) * 1997-11-11 2001-06-26 Ono Pharmaceutical Co., Ltd. Human lysophosphatidic acid receptor and use thereof
US6207412B1 (en) * 1997-11-13 2001-03-27 The Regents Of The University Of California Identification of a G protein-coupled receptor transcriptionally regulated by protein tyrosine kinase signaling in hematopoietic cells
WO1999042484A1 (en) * 1998-02-20 1999-08-26 Smithkline Beecham Corporation Fishboy, a g-protein coupled receptor
EP1690939B8 (en) * 1998-03-12 2010-10-13 Astellas Pharma Inc. Novel G protein-coupled receptor proteins
AU3749499A (en) * 1998-04-16 1999-11-01 Millenium Pharmaceuticals, Inc. Novel molecules of the bgckr-related protein family and uses thereof
SE9801455D0 (sv) * 1998-04-24 1998-04-24 Astra Pharma Inc New receptor
JP2002512780A (ja) * 1998-04-24 2002-05-08 スミスクライン ビーチャム コーポレーション 新規７ｔｍ受容体ａｘｏｒ−２のクローニング
US6071722A (en) * 1998-04-24 2000-06-06 Smithkline Beecham Corporation Nucleic acids encoding a G-protein coupled 7TM receptor (AXOR-1)
CA2340334A1 (en) * 1998-08-19 2000-03-02 Millenium Pharmaceuticals, Inc. 14274 receptor, a g-protein coupled receptor related to the edg receptor family
AU5578699A (en) * 1998-08-20 2000-03-14 Millennium Pharmaceuticals, Inc. 14400 receptor, a g-protein coupled receptor
AU5784799A (en) * 1998-08-24 2000-03-14 Alphagene, Inc. Secreted proteins and polynucleotides encoding them
AU5801099A (en) * 1998-09-02 2000-03-21 Millennium Pharmaceuticals, Inc. 14926 receptor, a novel g-protein coupled receptor
IL142153A0 (en) * 1998-10-13 2002-03-10 Arena Pharm Inc Non-endogenous, constitutively activated human g protein-coupled receptors
JP2004500013A (ja) * 1998-10-16 2004-01-08 ミレニアム・ファーマシューティカルズ・インコーポレイテッド 新規ｇタンパク質共役受容体
WO2000026369A1 (en) * 1998-11-04 2000-05-11 Chiron Corporation Isolated vshk-1 receptor polypeptides and methods of use thereof
EP1127126B1 (en) * 1998-11-06 2006-10-18 Bayer HealthCare AG G-protein coupled receptors, homologous to ebv-induced gpcr 2 (ebi-2). methods to seek for ligands thereof
US6221660B1 (en) * 1999-02-22 2001-04-24 Synaptic Pharmaceutical Corporation DNA encoding SNORF25 receptor
US6689866B1 (en) * 1999-03-09 2004-02-10 Curagen Corporation Polynucleotides and proteins encoded thereby
US6590938B1 (en) * 1999-09-30 2003-07-08 Conexant Systems, Inc. DCT domain conversion of a higher definition signal to lower definition signal
GB9923177D0 (en) * 1999-09-30 1999-12-01 Pfizer Ltd Novel polypeptide

Also Published As

Publication number Publication date
ES2243095T3 (es) 2005-11-16
CA2348377C (en) 2008-12-02
KR100926208B1 (ko) 2009-11-09
KR100765039B1 (ko) 2007-10-09
IL142538A (en) 2010-11-30
JP2004267216A (ja) 2004-09-30
KR100963367B1 (ko) 2010-06-14
JP2008133300A (ja) 2008-06-12
KR20070097564A (ko) 2007-10-04
HK1037675A1 (en) 2002-02-15
JP2009298791A (ja) 2009-12-24
DK1584683T3 (da) 2007-10-29
EP2295574A1 (en) 2011-03-16
ATE301673T1 (de) 2005-08-15
KR100926209B1 (ko) 2009-11-09
ES2308759T3 (es) 2008-12-01
EP1584683A1 (en) 2005-10-12
WO2000031258A2 (en) 2000-06-02
JP2007209352A (ja) 2007-08-23
DK1133559T3 (da) 2006-04-10
CA2348377A1 (en) 2000-06-02
NZ537625A (en) 2006-08-31
PT1849866E (pt) 2008-08-28
IL142538A0 (en) 2002-03-10
ATE396400T1 (de) 2008-06-15
PT1133559E (pt) 2005-10-31
DK1849866T3 (da) 2008-09-08
EP1580271A2 (en) 2005-09-28
EP1584683B1 (en) 2007-07-11
ES2289610T3 (es) 2008-02-01
JP2003534767A (ja) 2003-11-25
EP1780280A1 (en) 2007-05-02
KR20010086040A (ko) 2001-09-07
NZ527622A (en) 2005-03-24
HK1103763A1 (en) 2007-12-28
EP1133559B1 (en) 2005-08-10
WO2000031258A3 (en) 2000-10-05
AU2004202147A1 (en) 2004-06-10
PT1584683E (pt) 2007-10-17
EP1133559A2 (en) 2001-09-19
NZ511087A (en) 2004-01-30
AU770056B2 (en) 2004-02-12
CA2645717A1 (en) 2000-06-02
KR20080024233A (ko) 2008-03-17
EP1580271A3 (en) 2006-01-18
EP1849866A3 (en) 2007-11-07
EP1849866A2 (en) 2007-10-31
KR20080104062A (ko) 2008-11-28
EP1849866B1 (en) 2008-05-21
EP2295572A1 (en) 2011-03-16
KR20080024234A (ko) 2008-03-17
EP2295573A1 (en) 2011-03-16
AU3790400A (en) 2000-06-13

Similar Documents

Publication Publication Date Title
ATE366815T1 (de) Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand
NO20041325L (no) Substanser
DK1009732T3 (da) 1-Amino-alkylcyclohexan NMDA receptor antagonister
CY1107339T1 (el) Mu-1, μελος της οικογενειας υποδοχεα κυτοκινης
DE60134762D1 (de) Metabotropische glutamatrezeptor-antagonisten
DE69709561D1 (de) Östrogen-Rezeptor
SMP200600024B (it) 2,6-Biseteroaril-4-amminopirimidine come antagonisti del recettore dell'adenosina
ATE272114T1 (de) Rezeptoren für il-18
DE602004021250D1 (de) 2-alkinyl- und 2-alkenyl-pyrazolo-ä4,3-eü -1,2,4-triazolo-ä1,5-cü -pyrimidinadenosin a2a rezeptorantagonisten
DK1068202T3 (da) 1-(-heteroarylpropyl- eller -prop-2-enyl)-4benzylpipderidiner som NMDA-receptor-antagonister
WO2002068600A3 (en) Endogenous and non-endogenous versions of human g protein-coupled receptors
DE69939053D1 (de) 2-arylethyl-(piperidin-4-ylmethyl)amine derivatives als muskarin-rezeptor antagonisten
NO20042198L (no) Tetrahydrokarbazolderivater som ligander for G-proteinkoplede reseptorer (GPCR).
ES2147167T1 (es) Procedimiento de identificacion de moduladores de receptores de membrana de superficie celular util para el tratamiento de enfermedades.
EP1157097A4 (en) GALANINE RECEPTOR-LIKE G-PROTEIN-COUPLED RECEPTOR
DE50008020D1 (de) Substituierte pyrrolidin-2,3,4-trion-derivate wirksam als nmda-rezeptor-antagonisten
SE9702794D0 (sv) New compounds
DE60305450T8 (de) Substituierte 10-Aryl-11H-Benzo(b)bluorene für selektive Effekte auf Östrogen-Rezeptoren
CY1108264T1 (el) Ανθρωπινος ορφανος συζευγμενος σε g πρωτεϊνη υποδοχεας rup3
EP0943685A3 (de) Neuer G-Protein-gekoppelter Rezeptor aus menschlichem Gehirn
NO20011779L (no) Ureidopiperidinderivater som selektive humane NK3 reseptor antagonister
EP1017709A4 (en) HOMMAL GLYCOPROTEIC RECEPTOR AOMF05 COUPLED BY G PROTEINS
DE69936550D1 (de) Menschliche, an ein G-Protein gekoppelter Rezeptor RUP3 ohne bekannten Ligand
BR9603432A (pt) Antagonistas de receptores de endotelina
ATE310732T1 (de) 7-phenyl-1,4-diazepanderivate als neurokininrezeptorantagonisten

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1584683

Country of ref document: EP