ATE365327T1 - Verfahren zum nachweis von zelltod mittels cytochrom c. - Google Patents

Verfahren zum nachweis von zelltod mittels cytochrom c.

Info

Publication number
ATE365327T1
ATE365327T1 AT00974820T AT00974820T ATE365327T1 AT E365327 T1 ATE365327 T1 AT E365327T1 AT 00974820 T AT00974820 T AT 00974820T AT 00974820 T AT00974820 T AT 00974820T AT E365327 T1 ATE365327 T1 AT E365327T1
Authority
AT
Austria
Prior art keywords
cytochrome
cell death
detecting cell
body fluid
determining
Prior art date
Application number
AT00974820T
Other languages
English (en)
Inventor
Fumio Endo
Naoto Adachi
Hiroyuki Nunoi
Keisuke Watanabe
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Application granted granted Critical
Publication of ATE365327T1 publication Critical patent/ATE365327T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/795—Porphyrin- or corrin-ring-containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2510/00—Detection of programmed cell death, i.e. apoptosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT00974820T 1999-11-08 2000-11-08 Verfahren zum nachweis von zelltod mittels cytochrom c. ATE365327T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP31647599 1999-11-08
JP2000274257 2000-09-11

Publications (1)

Publication Number Publication Date
ATE365327T1 true ATE365327T1 (de) 2007-07-15

Family

ID=26568676

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00974820T ATE365327T1 (de) 1999-11-08 2000-11-08 Verfahren zum nachweis von zelltod mittels cytochrom c.

Country Status (7)

Country Link
US (2) US7070924B1 (de)
EP (1) EP1229328B1 (de)
JP (1) JP3869722B2 (de)
AT (1) ATE365327T1 (de)
DE (1) DE60035286T2 (de)
ES (1) ES2288877T3 (de)
WO (1) WO2001035093A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7541150B2 (en) 2002-04-08 2009-06-02 University Of Louisville Research Foundation, Inc Method for the diagnosis and prognosis of malignant diseases
US7357928B2 (en) 2002-04-08 2008-04-15 University Of Louisville Research Foundation, Inc. Method for the diagnosis and prognosis of malignant diseases
JP2005530515A (ja) * 2002-06-26 2005-10-13 ユニヴァーシティー オヴ ルイスヴィル リサーチ ファウンデイション インコーポレイテッド アポトーシスの検出方法
US20060263809A1 (en) * 2005-04-05 2006-11-23 The Rgents Of The University Of California Method for sensitive measure of low level apoptosis in cells
JP4896022B2 (ja) * 2005-04-15 2012-03-14 エーザイ・アール・アンド・ディー・マネジメント株式会社 チトクロムｃの免疫化学的測定方法及び測定キット
JP5176239B2 (ja) 2006-04-06 2013-04-03 エーザイ・アール・アンド・ディー・マネジメント株式会社 チトクロムｃの定量による非アルコール性脂肪性肝炎の非侵襲的な検査方法及び検査キット
JP5152766B2 (ja) * 2008-03-10 2013-02-27 エーザイ・アール・アンド・ディー・マネジメント株式会社 癌の浸潤と転移の検査方法及び検査用試薬
JP5483141B2 (ja) * 2008-04-23 2014-05-07 学校法人日本医科大学 脳症由来痙攣と発熱由来熱性痙攣の鑑別方法
EP2813848A3 (de) * 2008-08-29 2015-03-11 Astute Medical, Inc. Verfahren und Zusammensetzungen zur Diagnose und Prognose von Nierenläsion und Niereninsuffizienz
EP3037435B1 (de) 2009-11-17 2019-08-07 MUSC Foundation for Research Development Humane monoklonale antikörper gegen menschliches nukleolin
EP3279668B1 (de) * 2010-12-16 2019-05-15 National Institute of Advanced Industrial Science and Technology Verfahren zur anreicherung und trennung von rückenmarkflüssigkeitsglykoprotein, verfahren zum suchen von markern für erkrankungen des zentralnervensystems unter verwendung des vorgenannten verfahrens und marker für erkrankungen des zentralnervensystems
EP3011974B1 (de) 2011-06-02 2018-08-08 University Of Louisville Research Foundation, Inc. Mit einem anti-nukleolin-wirkstoff konjugierte nanopartikel
US10012648B2 (en) 2014-06-03 2018-07-03 Yale University Plasma cytochrome C as a biomarker for mitochondrial toxicity during antiretroviral therapy
WO2016179394A1 (en) 2015-05-05 2016-11-10 Malik Mohammad Tariq Anti-nucleolin agent-conjugated nanoparticles as radio-sensitizers and mri and/or x-ray contrast agents

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4107334A1 (de) * 1990-03-08 1991-09-12 Morinaga & Co Serum-diagnoseverfahren und dafuer geeigneter diagnosesatz
JPH03257367A (ja) * 1990-03-08 1991-11-15 Morinaga & Co Ltd 血清診断法
US5780237A (en) * 1994-10-12 1998-07-14 Cell Therapeutics, Inc. Sepsis, adult respiratory distress syndrome, and systemic inflammatory response syndrome diagnostic
WO1998002579A1 (en) 1996-07-12 1998-01-22 Emory University Regulation of apoptosis and in vitro model for studies thereof
EP1301786B1 (de) * 2000-07-21 2005-11-30 Evotec AG Verfahren zur detektion der apoptose durch ermittlung von cytochrom c als apoptosespezifischem marker, der durch zelluläre ausschüttungsvorgänge ins extrazelluläre medium abgegeben wird
US7138239B2 (en) * 2001-05-09 2006-11-21 Eisai Co., Ltd. Method and reagent for testing for multiple organ failure in SIRS by cytochrome C measurement
JP2005147783A (ja) * 2003-11-13 2005-06-09 Eisai Co Ltd チトクロムｃによる細胞死の診断薬

Also Published As

Publication number Publication date
ES2288877T3 (es) 2008-02-01
JP3869722B2 (ja) 2007-01-17
WO2001035093A1 (fr) 2001-05-17
EP1229328A1 (de) 2002-08-07
DE60035286D1 (de) 2007-08-02
US20060183176A1 (en) 2006-08-17
EP1229328A4 (de) 2005-02-23
US7070924B1 (en) 2006-07-04
DE60035286T2 (de) 2008-02-21
EP1229328B1 (de) 2007-06-20

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