ATE359794T1 - 3, 7 thiaprostansäurederivate als mittel zur verminderung des augeninnendruckes - Google Patents

3, 7 thiaprostansäurederivate als mittel zur verminderung des augeninnendruckes

Info

Publication number
ATE359794T1
ATE359794T1 AT02734233T AT02734233T ATE359794T1 AT E359794 T1 ATE359794 T1 AT E359794T1 AT 02734233 T AT02734233 T AT 02734233T AT 02734233 T AT02734233 T AT 02734233T AT E359794 T1 ATE359794 T1 AT E359794T1
Authority
AT
Austria
Prior art keywords
thiaprostanic
agent
acid derivatives
reducing internal
eye pressure
Prior art date
Application number
AT02734233T
Other languages
German (de)
English (en)
Inventor
Robert M Burk
Mark Holoboski
Mari F Posner
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Application granted granted Critical
Publication of ATE359794T1 publication Critical patent/ATE359794T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Paper (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Window Of Vehicle (AREA)
AT02734233T 2001-05-08 2002-05-06 3, 7 thiaprostansäurederivate als mittel zur verminderung des augeninnendruckes ATE359794T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/851,296 US6410591B1 (en) 2001-05-08 2001-05-08 3,7 or 3 and 7 thia or oxa prostanoic acid derivatives as agents for lowering intraocular pressure

Publications (1)

Publication Number Publication Date
ATE359794T1 true ATE359794T1 (de) 2007-05-15

Family

ID=25310439

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02734233T ATE359794T1 (de) 2001-05-08 2002-05-06 3, 7 thiaprostansäurederivate als mittel zur verminderung des augeninnendruckes

Country Status (9)

Country Link
US (1) US6410591B1 (enExample)
EP (1) EP1385526B1 (enExample)
JP (1) JP2004529166A (enExample)
AT (1) ATE359794T1 (enExample)
AU (1) AU2002305416B2 (enExample)
CA (1) CA2446386C (enExample)
DE (1) DE60219614T2 (enExample)
ES (1) ES2284872T3 (enExample)
WO (1) WO2002089813A2 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6410591B1 (en) * 2001-05-08 2002-06-25 Allergan Sales, Inc. 3,7 or 3 and 7 thia or oxa prostanoic acid derivatives as agents for lowering intraocular pressure
US7872045B2 (en) * 2001-06-14 2011-01-18 Allergan, Inc. Combination therapy for glaucoma treatment
US20030027853A1 (en) 2001-06-14 2003-02-06 Allergan Sales, Inc. 3, 7or3 and 7 thia or oxa prostanoic acid derivatives as agents for lowering intraocular pressure
US20050222094A1 (en) * 2001-06-14 2005-10-06 Burk Robert M Treatment of inflammatory bowel disease
KR101077461B1 (ko) * 2003-02-11 2011-10-26 알러간, 인코포레이티드 안압 강하제로서의 10,10-디알킬 프로스탄산 유도체
US7179820B2 (en) * 2003-06-06 2007-02-20 Allergan, Inc. Piperidinyl prostaglandin E analogs
US7186744B2 (en) * 2003-11-13 2007-03-06 Allergan, Inc. Prostamides for the treatment of glaucoma and related diseases
WO2006041875A1 (en) 2004-10-06 2006-04-20 Allergan, Inc. Novel prostamides for the treatment of glaucoma and related diseases
US7183324B2 (en) * 2004-11-23 2007-02-27 Allergan, Inc. 2,3,4-substituted cyclopentanones as therapeutic agents
US7893107B2 (en) * 2005-11-30 2011-02-22 Allergan, Inc. Therapeutic methods using prostaglandin EP4 agonist components
US20070232660A1 (en) * 2006-04-04 2007-10-04 Allergan, Inc. Therapeutic and delivery methods of prostaglandin ep4 agonists
CA2669763C (en) 2006-11-16 2015-02-17 Bayer Schering Pharma Aktiengesellschaft Ep2 and ep4 agonists as agents for the treatment of influenza a viral infection
US8455547B2 (en) * 2008-02-05 2013-06-04 Allergan, Inc. Substituted cyclopentanes having prostaglandin activity
US7732443B2 (en) * 2008-03-18 2010-06-08 Yariv Donde Therapeutic substituted cyclopentanes
US7960378B2 (en) * 2008-03-18 2011-06-14 Allergan, Inc. Therapeutic compounds
RU2500674C2 (ru) * 2008-05-09 2013-12-10 Аллерган, Инк. Терапевтические соединения
EP2149552A1 (de) 2008-07-30 2010-02-03 Bayer Schering Pharma AG 5,6 substituierte Benzamid-Derivate als Modulatoren des EP2-Rezeptors
EP2149554A1 (de) 2008-07-30 2010-02-03 Bayer Schering Pharma Aktiengesellschaft Indolylamide als Modulatoren des EP2-Rezeptors
EP2149551A1 (de) 2008-07-30 2010-02-03 Bayer Schering Pharma AG N-(Indol-3-ylalkyl)-(hetero)arylamidderivate als Modulatoren des EP2-Rezeptors
US20110293549A1 (en) 2009-02-03 2011-12-01 Athena Cosmetics, Inc. Composition, method and kit for enhancing hair
US8859616B2 (en) * 2011-01-21 2014-10-14 Allergan, Inc. Compounds and methods for enhancing hair growth
CN109072186B (zh) 2016-03-04 2023-06-23 莱兰斯坦福初级大学评议会 利用前列腺素e2进行肌肉再生的组合物和方法
JP7372911B2 (ja) 2017-06-09 2023-11-01 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 筋肉の状態を予防または治療するための組成物および方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4937265A (en) * 1987-05-28 1990-06-26 Teijin Limited Antidiabetic method comprising 7-thiaprostaglandin E1 or its derivatives
JP3579448B2 (ja) * 1993-12-29 2004-10-20 大正製薬株式会社 プロスタグランジン誘導体、その塩およびその使用
JPH09286775A (ja) * 1996-04-24 1997-11-04 Taisho Pharmaceut Co Ltd プロスタグランジン誘導体
JPH10259179A (ja) * 1996-09-19 1998-09-29 Santen Pharmaceut Co Ltd 多置換アリールオキシ基を有するプロスタグランジン類およびその用途
JPH10265454A (ja) 1997-01-27 1998-10-06 Ono Pharmaceut Co Ltd ３，７−ジチアプロスタン酸誘導体、それらの製造方法およびそれらを有効成分として含有する薬剤
NO317155B1 (no) * 1997-02-04 2004-08-30 Ono Pharmaceutical Co <omega>-cykloalkyl-prostagladin-E<N>2</N>-derivater
US6043275A (en) 1998-04-16 2000-03-28 Ono Pharmaceutical Co., Ltd. 3,7-dithiaprostanoic acid derivative
AU2183900A (en) * 1998-12-24 2000-07-31 Alcon Laboratories, Inc. Ep4 receptor agonists for treatment of dry eye
US6545045B1 (en) * 1998-12-24 2003-04-08 Alcon Manufacturing, Ltd. Prostaglandin E agonists for treatment of glaucoma
JP2001151749A (ja) * 1999-11-24 2001-06-05 Taisho Pharmaceut Co Ltd プロスタグランジン誘導体
US6410591B1 (en) * 2001-05-08 2002-06-25 Allergan Sales, Inc. 3,7 or 3 and 7 thia or oxa prostanoic acid derivatives as agents for lowering intraocular pressure
EP1461026A2 (en) * 2001-12-03 2004-09-29 Merck & Co., Inc. Method for treating ocular hypertension

Also Published As

Publication number Publication date
AU2002305416B2 (en) 2008-01-10
JP2004529166A (ja) 2004-09-24
WO2002089813A3 (en) 2003-02-27
WO2002089813A2 (en) 2002-11-14
ES2284872T3 (es) 2007-11-16
EP1385526A2 (en) 2004-02-04
DE60219614D1 (de) 2007-05-31
CA2446386A1 (en) 2002-11-14
US6410591B1 (en) 2002-06-25
DE60219614T2 (de) 2007-12-27
EP1385526B1 (en) 2007-04-18
CA2446386C (en) 2011-02-01

Similar Documents

Publication Publication Date Title
ATE359794T1 (de) 3, 7 thiaprostansäurederivate als mittel zur verminderung des augeninnendruckes
BR0310047A (pt) Análogos de 8-azaprostaglandina como agentes para diminuição de pressão intra-ocular
ATE453395T1 (de) 3, 7 oder 3 und 7 thia- oder oxaprostansäure derivate als mittel zur senkung des augeninnendrucks
BRPI0418245A (pt) nitróxi-derivados de prostaglandina
BR0213738A (pt) proteìnas morfogênicas ósseas (bmp), receptores de bmp e proteìnas de ligação de bmp e seu uso no diagnóstico e no tratamento de glaucoma
CY1110969T1 (el) 5-υποκατεστημενα-2-φαινυλαμινο-βενζαμιδια ως αναστολεiς μεκ
WO2003047513A3 (en) Method for treating ocular hypertension
WO2002009702A3 (en) Use of indole derivatives for the manufacture of a medicament for reducing intracular pressure
WO2003072066A3 (en) Compositions and methods for the treatment of glaucoma and ocular hypertension
BR0211604A (pt) Inibidores de integrina para o tratamento de doenças do olho
BR0017157A (pt) Derivados de 6-hidroxi-indazol para o tratamento de glaucoma
BR9907715A (pt) Composição oftálmica/método para tratamento de lesão córnea e/ou de estesia córnea deteriordada, sìndrome de olho seco, hipolarcrimação e uso de um inibidor de redutase de aldose
WO2001091796A8 (en) Methods, compounds and compositions for treating gout
ATE369856T1 (de) Verfahren zur behandlung von glaukom
BR0017158A (pt) Agonistas de 5ht2 para controlar a iop e tratar o glaucoma
MXPA02011921A (es) Inhibidores de dipeptidasa acida n-acetilada-alfa-enlazada para el tratamiento de trastornos retinianos y glaucona.
BRPI0518690A2 (pt) tratamento de doenÇa inflamatària do intestino
DE60135972D1 (de) Orhthalmologische zusammenstellungen zur behandlung von ocularer hypertension
HUT77135A (hu) Eljárás I típusú allergiás betegségek megelőzésére és kezelésére alkalmazható gyógyszerkészítmények előállítására
BR0316775A (pt) Novos análogos de benzopirano e seu uso para o tratamento de glaucoma
EA200201232A1 (ru) Производные сульфонамида
ATE496886T1 (de) 3-oxa-8-azaprostaglandinanaloga als mittel zum senken des augeninnendrucks
BR0209601A (pt) Método para o tratamento da hipertensão ocular e do glaucoma
ATE215824T1 (de) Mittel zur verminderung des augeninnendrucks
PT1251826E (pt) Gel de suspensao de ciclofenamida

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties