ATE359276T1 - Aryloxyphenyl und arylsulfanylphenylderivate - Google Patents
Aryloxyphenyl und arylsulfanylphenylderivateInfo
- Publication number
- ATE359276T1 ATE359276T1 AT02787451T AT02787451T ATE359276T1 AT E359276 T1 ATE359276 T1 AT E359276T1 AT 02787451 T AT02787451 T AT 02787451T AT 02787451 T AT02787451 T AT 02787451T AT E359276 T1 ATE359276 T1 AT E359276T1
- Authority
- AT
- Austria
- Prior art keywords
- arylsulfanylphenyl
- aryloxyphenyl
- derivatives
- compounds
- valuable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34265301P | 2001-12-20 | 2001-12-20 | |
| DKPA200101927 | 2001-12-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE359276T1 true ATE359276T1 (de) | 2007-05-15 |
Family
ID=26069114
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02787451T ATE359276T1 (de) | 2001-12-20 | 2002-12-16 | Aryloxyphenyl und arylsulfanylphenylderivate |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7067501B2 (de) |
| EP (1) | EP1458689B1 (de) |
| JP (1) | JP2005513128A (de) |
| CN (1) | CN100457738C (de) |
| AT (1) | ATE359276T1 (de) |
| AU (1) | AU2002351734A1 (de) |
| CA (1) | CA2467118A1 (de) |
| DE (1) | DE60219521T2 (de) |
| ES (1) | ES2280595T3 (de) |
| HK (1) | HK1076807A1 (de) |
| HU (1) | HUP0402320A2 (de) |
| IL (1) | IL161966A0 (de) |
| IS (1) | IS7258A (de) |
| MX (1) | MXPA04005989A (de) |
| NO (1) | NO20042885L (de) |
| WO (1) | WO2003053942A1 (de) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA81749C2 (uk) | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
| CN1867358A (zh) * | 2003-08-21 | 2006-11-22 | H.隆德贝克有限公司 | 用于治疗抑郁症的5－羟色胺再摄取抑制剂和1型甘氨酸转运蛋白抑制剂的联合药物 |
| WO2005058317A1 (en) * | 2003-12-18 | 2005-06-30 | Glaxo Group Limited | Glycine transporter-1 inhibirors |
| WO2005058885A2 (en) * | 2003-12-18 | 2005-06-30 | Glaxo Group Limited | Piperidine derivatives and their use as glycine transporter inhibitors |
| EP1716147B1 (de) * | 2004-01-08 | 2007-11-14 | F.Hoffmann-La Roche Ag | Diazaspiropiperidinderivate als inhibitoren von glycintransporter 1 und glycintransporter 2 |
| WO2006000222A2 (en) * | 2004-06-24 | 2006-01-05 | H. Lundbeck A/S | The combination of an antipsychotic and a glycine transporter type i inhibitor for the treatment of schizophrenia |
| US7485637B2 (en) * | 2005-01-04 | 2009-02-03 | Hoffmann-La Roche Inc. | Benzoyl-tetrahydropiperidine derivatives |
| PL2044043T5 (pl) | 2006-06-16 | 2022-05-02 | H. Lundbeck A/S | Bromowodorek 1-[2-(2,4-dimetylofenylosulfanylo)fenylo]piperazyny jako związek o połączonym działaniu wychwytu zwrotnego serotoniny i działaniu na 5-ht3 i 5-ht1a do leczenia upośledzenia funckji poznawczych |
| SG172685A1 (en) * | 2006-06-28 | 2011-07-28 | Amgen Inc | Glycine transporter-1 inhibitors |
| TW200848411A (en) * | 2007-03-20 | 2008-12-16 | Lundbeck & Co As H | Novel therapeutic uses of 1-[2-(2, 4-dimethylphenylsulfanyl)phenyl]-piperazine |
| CN101784533B (zh) | 2007-08-22 | 2013-08-21 | 艾博特股份有限两合公司 | 4-苄基氨基喹啉、含有它们的药物组合物和它们在治疗中的用途 |
| TW200932233A (en) * | 2007-11-13 | 2009-08-01 | Lundbeck & Co As H | Therapeutic uses of compounds having combined SERT, 5-HT3 and 5-HT1a activity |
| AU2008335788B2 (en) | 2007-12-12 | 2012-11-29 | Amgen Inc. | Glycine transporter-1 inhibitors |
| EP2271625B1 (de) | 2008-04-01 | 2012-09-12 | Abbott GmbH & Co. KG | Tetrahydroisochinoline, pharmazeutische zusammensetzungen damit und ihre therapeutische verwendung |
| TW201038569A (en) | 2009-02-16 | 2010-11-01 | Abbott Gmbh & Co Kg | Heterocyclic compounds, pharmaceutical compositions containing them, and their use in therapy |
| AR075442A1 (es) | 2009-02-16 | 2011-03-30 | Abbott Gmbh & Co Kg | Derivados de aminotetralina, composiciones farmaceuticas que las contienen y sus usos en terapia |
| JP6173693B2 (ja) * | 2010-02-24 | 2017-08-02 | リサーチ・トライアングル・インスティチュート | アリールピペラジンオピオイド受容体アンタゴニスト |
| US9045459B2 (en) | 2010-08-13 | 2015-06-02 | AbbVie Deutschland GmbH & Co. KG | Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US8883839B2 (en) | 2010-08-13 | 2014-11-11 | Abbott Laboratories | Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US9051280B2 (en) | 2010-08-13 | 2015-06-09 | AbbVie Deutschland GmbH & Co. KG | Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US8846743B2 (en) | 2010-08-13 | 2014-09-30 | Abbott Laboratories | Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US8877794B2 (en) | 2010-08-13 | 2014-11-04 | Abbott Laboratories | Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US9309200B2 (en) | 2011-05-12 | 2016-04-12 | AbbVie Deutschland GmbH & Co. KG | Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| CN103889968A (zh) | 2011-08-05 | 2014-06-25 | 艾伯维德国有限责任两合公司 | 氨基苯并二氢吡喃、氨基苯并二氢噻喃及氨基-1,2,3,4-四氢喹啉衍生物，包含这些化合物的药用组合物，及其在治疗中的用途 |
| CA2853254A1 (en) | 2011-11-18 | 2013-05-23 | Abbvie Inc. | N-substituted aminobenzocycloheptene, aminotetraline, aminoindane and phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| AU2012364402B2 (en) * | 2012-01-03 | 2016-10-06 | H. Lundbeck A/S | Process for the manufacture of 1-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]-piperazine |
| US9365512B2 (en) | 2012-02-13 | 2016-06-14 | AbbVie Deutschland GmbH & Co. KG | Isoindoline derivatives, pharmaceutical compositions containing them, and their use in therapy |
| MX362355B (es) * | 2013-02-22 | 2019-01-14 | H Lundbeck As | Proceso de fabricacion de vortioxetina. |
| US9650334B2 (en) | 2013-03-15 | 2017-05-16 | Abbvie Inc. | Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US9656955B2 (en) | 2013-03-15 | 2017-05-23 | Abbvie Inc. | Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| JP2016537323A (ja) | 2013-10-17 | 2016-12-01 | アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー | アミノクロマン誘導体、アミノチオクロマン誘導体およびアミノ−１，２，３，４−テトラヒドロキノリン誘導体、これらを含有する医薬組成物、および治療におけるこれらの使用 |
| EP3057958B1 (de) | 2013-10-17 | 2019-05-01 | AbbVie Deutschland GmbH & Co. KG | Aminotetralin- und aminoindanderivate, pharmazeutische zusammensetzungen damit und deren verwendung in der therapie |
| US9550754B2 (en) | 2014-09-11 | 2017-01-24 | AbbVie Deutschland GmbH & Co. KG | 4,5-dihydropyrazole derivatives, pharmaceutical compositions containing them, and their use in therapy |
| KR101753617B1 (ko) * | 2016-05-10 | 2017-07-11 | 주식회사 뉴로벤티 | 피페라진-1-카복사미딘 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 자폐 범주성 장애 예방 및 치료용 약학적 조성물 |
| CN109311833B (zh) | 2016-06-16 | 2022-11-04 | 广东东阳光药业有限公司 | 二芳基硫醚哌嗪类化合物及其制备方法和用途 |
| CN106279071B (zh) * | 2016-08-10 | 2019-01-04 | 广东东阳光药业有限公司 | 苯基哌嗪衍生物及其使用方法和用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5730738A (en) | 1995-12-04 | 1998-03-24 | The Procter & Gamble Company | Absorbent article with angled band structural elastic-like film cuffs |
| JPH10152470A (ja) * | 1996-09-25 | 1998-06-09 | Yoshitomi Pharmaceut Ind Ltd | ピペラジン化合物 |
| US6218547B1 (en) * | 1996-10-21 | 2001-04-17 | Neurosearch A/S | 1-phenyl-benzimidazole compounds and their use as GABA-a receptor modulators |
| CN1867358A (zh) * | 2003-08-21 | 2006-11-22 | H.隆德贝克有限公司 | 用于治疗抑郁症的5－羟色胺再摄取抑制剂和1型甘氨酸转运蛋白抑制剂的联合药物 |
-
2002
- 2002-12-16 CN CNB028257022A patent/CN100457738C/zh not_active Expired - Fee Related
- 2002-12-16 JP JP2003554658A patent/JP2005513128A/ja active Pending
- 2002-12-16 HU HU0402320A patent/HUP0402320A2/hu unknown
- 2002-12-16 AT AT02787451T patent/ATE359276T1/de not_active IP Right Cessation
- 2002-12-16 ES ES02787451T patent/ES2280595T3/es not_active Expired - Lifetime
- 2002-12-16 EP EP02787451A patent/EP1458689B1/de not_active Expired - Lifetime
- 2002-12-16 CA CA002467118A patent/CA2467118A1/en not_active Abandoned
- 2002-12-16 MX MXPA04005989A patent/MXPA04005989A/es unknown
- 2002-12-16 WO PCT/DK2002/000859 patent/WO2003053942A1/en active IP Right Grant
- 2002-12-16 AU AU2002351734A patent/AU2002351734A1/en not_active Abandoned
- 2002-12-16 IL IL16196602A patent/IL161966A0/xx unknown
- 2002-12-16 DE DE60219521T patent/DE60219521T2/de not_active Expired - Fee Related
-
2004
- 2004-05-10 IS IS7258A patent/IS7258A/is unknown
- 2004-05-20 US US10/851,769 patent/US7067501B2/en not_active Expired - Fee Related
- 2004-07-07 NO NO20042885A patent/NO20042885L/no not_active Application Discontinuation
-
2005
- 2005-10-05 HK HK05108830.2A patent/HK1076807A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US7067501B2 (en) | 2006-06-27 |
| DE60219521D1 (de) | 2007-05-24 |
| JP2005513128A (ja) | 2005-05-12 |
| HK1076807A1 (en) | 2006-01-27 |
| EP1458689B1 (de) | 2007-04-11 |
| DE60219521T2 (de) | 2007-08-16 |
| IS7258A (is) | 2004-05-10 |
| MXPA04005989A (es) | 2004-09-27 |
| ES2280595T3 (es) | 2007-09-16 |
| IL161966A0 (en) | 2005-11-20 |
| WO2003053942A1 (en) | 2003-07-03 |
| US20050171061A1 (en) | 2005-08-04 |
| AU2002351734A1 (en) | 2003-07-09 |
| HUP0402320A2 (hu) | 2005-03-29 |
| EP1458689A1 (de) | 2004-09-22 |
| CA2467118A1 (en) | 2003-07-03 |
| CN100457738C (zh) | 2009-02-04 |
| CN1606548A (zh) | 2005-04-13 |
| NO20042885L (no) | 2004-07-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |