IL161966A0 - Aryloxyphenyl and arylsulfanylphenyl - Google Patents
Aryloxyphenyl and arylsulfanylphenylInfo
- Publication number
- IL161966A0 IL161966A0 IL16196602A IL16196602A IL161966A0 IL 161966 A0 IL161966 A0 IL 161966A0 IL 16196602 A IL16196602 A IL 16196602A IL 16196602 A IL16196602 A IL 16196602A IL 161966 A0 IL161966 A0 IL 161966A0
- Authority
- IL
- Israel
- Prior art keywords
- arylsulfanylphenyl
- aryloxyphenyl
- compounds
- valuable
- substituents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34265301P | 2001-12-20 | 2001-12-20 | |
DKPA200101927 | 2001-12-20 | ||
PCT/DK2002/000859 WO2003053942A1 (en) | 2001-12-20 | 2002-12-16 | Aryloxyphenyl and arylsulfanylphenyl derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
IL161966A0 true IL161966A0 (en) | 2005-11-20 |
Family
ID=26069114
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16196602A IL161966A0 (en) | 2001-12-20 | 2002-12-16 | Aryloxyphenyl and arylsulfanylphenyl |
Country Status (16)
Country | Link |
---|---|
US (1) | US7067501B2 (xx) |
EP (1) | EP1458689B1 (xx) |
JP (1) | JP2005513128A (xx) |
CN (1) | CN100457738C (xx) |
AT (1) | ATE359276T1 (xx) |
AU (1) | AU2002351734A1 (xx) |
CA (1) | CA2467118A1 (xx) |
DE (1) | DE60219521T2 (xx) |
ES (1) | ES2280595T3 (xx) |
HK (1) | HK1076807A1 (xx) |
HU (1) | HUP0402320A2 (xx) |
IL (1) | IL161966A0 (xx) |
IS (1) | IS7258A (xx) |
MX (1) | MXPA04005989A (xx) |
NO (1) | NO20042885L (xx) |
WO (1) | WO2003053942A1 (xx) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA81749C2 (uk) | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
WO2005018676A1 (en) * | 2003-08-21 | 2005-03-03 | H. Lundbeck A/S | The combination of a serotonin reuptake inhibitor and a glycine transporter type 1 inhibitor for the treatment of depression |
WO2005058317A1 (en) * | 2003-12-18 | 2005-06-30 | Glaxo Group Limited | Glycine transporter-1 inhibirors |
WO2005058885A2 (en) * | 2003-12-18 | 2005-06-30 | Glaxo Group Limited | Piperidine derivatives and their use as glycine transporter inhibitors |
AU2004313692B2 (en) * | 2004-01-08 | 2011-07-28 | F. Hoffmann-La Roche Ag | Diaza-spiropiperidine derivatives as inhibitors of glycine transporter 1 and glycine transporter 2 |
WO2006000222A2 (en) * | 2004-06-24 | 2006-01-05 | H. Lundbeck A/S | The combination of an antipsychotic and a glycine transporter type i inhibitor for the treatment of schizophrenia |
US7485637B2 (en) * | 2005-01-04 | 2009-02-03 | Hoffmann-La Roche Inc. | Benzoyl-tetrahydropiperidine derivatives |
BRPI0713425A2 (pt) | 2006-06-16 | 2012-03-13 | H. Lundbeck A/S | composto, composição farmacêutica, método para tratar uma doença, uso de um composto, e processos para a preparação de um composto, e para a fabricação de um composto |
SI2041088T1 (sl) * | 2006-06-28 | 2014-05-30 | Amgen Inc. | Inhibitorji transporter-1 glicina |
TW200848411A (en) * | 2007-03-20 | 2008-12-16 | Lundbeck & Co As H | Novel therapeutic uses of 1-[2-(2, 4-dimethylphenylsulfanyl)phenyl]-piperazine |
WO2009024611A2 (en) | 2007-08-22 | 2009-02-26 | Abbott Gmbh & Co. Kg | 4-benzylaminoquinolines, pharmaceutical compositions containing them and their use |
TW200932233A (en) * | 2007-11-13 | 2009-08-01 | Lundbeck & Co As H | Therapeutic uses of compounds having combined SERT, 5-HT3 and 5-HT1a activity |
ES2486299T3 (es) * | 2007-12-12 | 2014-08-18 | Amgen Inc. | Inhibidores del transportador de glicina 1 |
MX2010010773A (es) | 2008-04-01 | 2011-04-11 | Abbott Gmbh & Co Kg | Tetrahidroisoquinolinas, composiciones farmaceuticas que las contienen y su uso en terapia. |
AR075442A1 (es) | 2009-02-16 | 2011-03-30 | Abbott Gmbh & Co Kg | Derivados de aminotetralina, composiciones farmaceuticas que las contienen y sus usos en terapia |
TW201038569A (en) | 2009-02-16 | 2010-11-01 | Abbott Gmbh & Co Kg | Heterocyclic compounds, pharmaceutical compositions containing them, and their use in therapy |
EP2539706B1 (en) * | 2010-02-24 | 2015-03-04 | Research Triangle Institute | Arylpiperazine opioid receptor antagonists |
US9045459B2 (en) | 2010-08-13 | 2015-06-02 | AbbVie Deutschland GmbH & Co. KG | Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy |
US8883839B2 (en) | 2010-08-13 | 2014-11-11 | Abbott Laboratories | Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy |
US8846743B2 (en) | 2010-08-13 | 2014-09-30 | Abbott Laboratories | Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy |
US8877794B2 (en) | 2010-08-13 | 2014-11-04 | Abbott Laboratories | Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy |
US9051280B2 (en) | 2010-08-13 | 2015-06-09 | AbbVie Deutschland GmbH & Co. KG | Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy |
US9309200B2 (en) | 2011-05-12 | 2016-04-12 | AbbVie Deutschland GmbH & Co. KG | Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy |
US8853196B2 (en) | 2011-08-05 | 2014-10-07 | AbbVie Deutschland GmbH & Co. KG | Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy |
MX2014006004A (es) | 2011-11-18 | 2015-04-16 | Abbvie Deutschland | Derivados de aminobenzociclohepteno, aminotetralina, aminoindano y fenalcilamina n-sustituidas, composiciones farmaceuticas que los contienen, y su uso en terapia. |
EP2800746B1 (en) * | 2012-01-03 | 2019-04-17 | H. Lundbeck A/S | Process for the manufacture of 1-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]-piperazine |
US9365512B2 (en) | 2012-02-13 | 2016-06-14 | AbbVie Deutschland GmbH & Co. KG | Isoindoline derivatives, pharmaceutical compositions containing them, and their use in therapy |
RS55932B1 (sr) * | 2013-02-22 | 2017-09-29 | H Lundbeck As | Postupak za proizvodnju vortioksetina |
US9650334B2 (en) | 2013-03-15 | 2017-05-16 | Abbvie Inc. | Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy |
US9656955B2 (en) | 2013-03-15 | 2017-05-23 | Abbvie Inc. | Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy |
CN105992764A (zh) | 2013-10-17 | 2016-10-05 | 艾伯维德国有限责任两合公司 | 氨基色满、氨基硫代色满及氨基-1,2,3,4-四氢喹啉衍生物,包含其的药物组合物及其在治疗中的用途 |
CA2924699A1 (en) | 2013-10-17 | 2015-04-23 | AbbVie Deutschland GmbH & Co. KG | Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy |
US9550754B2 (en) | 2014-09-11 | 2017-01-24 | AbbVie Deutschland GmbH & Co. KG | 4,5-dihydropyrazole derivatives, pharmaceutical compositions containing them, and their use in therapy |
KR101753617B1 (ko) * | 2016-05-10 | 2017-07-11 | 주식회사 뉴로벤티 | 피페라진-1-카복사미딘 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 자폐 범주성 장애 예방 및 치료용 약학적 조성물 |
WO2017215636A1 (zh) | 2016-06-16 | 2017-12-21 | 广东东阳光药业有限公司 | 二芳基硫醚哌嗪类化合物及其制备方法和用途 |
CN106279071B (zh) * | 2016-08-10 | 2019-01-04 | 广东东阳光药业有限公司 | 苯基哌嗪衍生物及其使用方法和用途 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5730738A (en) | 1995-12-04 | 1998-03-24 | The Procter & Gamble Company | Absorbent article with angled band structural elastic-like film cuffs |
JPH10152470A (ja) * | 1996-09-25 | 1998-06-09 | Yoshitomi Pharmaceut Ind Ltd | ピペラジン化合物 |
RU2194699C2 (ru) * | 1996-10-21 | 2002-12-20 | Ньюросерч А/С | 1-фенил-бензимидазольные соединения, фармацевтическая композиция и способ лечения расстройства или заболевания, чувствительного к модуляции гамка-рецепторного комплекса центральной нервной системы |
WO2005018676A1 (en) * | 2003-08-21 | 2005-03-03 | H. Lundbeck A/S | The combination of a serotonin reuptake inhibitor and a glycine transporter type 1 inhibitor for the treatment of depression |
-
2002
- 2002-12-16 JP JP2003554658A patent/JP2005513128A/ja active Pending
- 2002-12-16 ES ES02787451T patent/ES2280595T3/es not_active Expired - Lifetime
- 2002-12-16 AU AU2002351734A patent/AU2002351734A1/en not_active Abandoned
- 2002-12-16 CA CA002467118A patent/CA2467118A1/en not_active Abandoned
- 2002-12-16 CN CNB028257022A patent/CN100457738C/zh not_active Expired - Fee Related
- 2002-12-16 MX MXPA04005989A patent/MXPA04005989A/es unknown
- 2002-12-16 DE DE60219521T patent/DE60219521T2/de not_active Expired - Fee Related
- 2002-12-16 IL IL16196602A patent/IL161966A0/xx unknown
- 2002-12-16 EP EP02787451A patent/EP1458689B1/en not_active Expired - Lifetime
- 2002-12-16 WO PCT/DK2002/000859 patent/WO2003053942A1/en active IP Right Grant
- 2002-12-16 HU HU0402320A patent/HUP0402320A2/hu unknown
- 2002-12-16 AT AT02787451T patent/ATE359276T1/de not_active IP Right Cessation
-
2004
- 2004-05-10 IS IS7258A patent/IS7258A/is unknown
- 2004-05-20 US US10/851,769 patent/US7067501B2/en not_active Expired - Fee Related
- 2004-07-07 NO NO20042885A patent/NO20042885L/no not_active Application Discontinuation
-
2005
- 2005-10-05 HK HK05108830.2A patent/HK1076807A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1458689B1 (en) | 2007-04-11 |
IS7258A (is) | 2004-05-10 |
WO2003053942A1 (en) | 2003-07-03 |
HUP0402320A2 (hu) | 2005-03-29 |
HK1076807A1 (en) | 2006-01-27 |
ES2280595T3 (es) | 2007-09-16 |
DE60219521D1 (de) | 2007-05-24 |
ATE359276T1 (de) | 2007-05-15 |
US20050171061A1 (en) | 2005-08-04 |
US7067501B2 (en) | 2006-06-27 |
AU2002351734A1 (en) | 2003-07-09 |
NO20042885L (no) | 2004-07-07 |
CA2467118A1 (en) | 2003-07-03 |
DE60219521T2 (de) | 2007-08-16 |
JP2005513128A (ja) | 2005-05-12 |
MXPA04005989A (es) | 2004-09-27 |
EP1458689A1 (en) | 2004-09-22 |
CN1606548A (zh) | 2005-04-13 |
CN100457738C (zh) | 2009-02-04 |
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