MX2014006004A - Derivados de aminobenzociclohepteno, aminotetralina, aminoindano y fenalcilamina n-sustituidas, composiciones farmaceuticas que los contienen, y su uso en terapia. - Google Patents

Derivados de aminobenzociclohepteno, aminotetralina, aminoindano y fenalcilamina n-sustituidas, composiciones farmaceuticas que los contienen, y su uso en terapia.

Info

Publication number
MX2014006004A
MX2014006004A MX2014006004A MX2014006004A MX2014006004A MX 2014006004 A MX2014006004 A MX 2014006004A MX 2014006004 A MX2014006004 A MX 2014006004A MX 2014006004 A MX2014006004 A MX 2014006004A MX 2014006004 A MX2014006004 A MX 2014006004A
Authority
MX
Mexico
Prior art keywords
aminotetraline
aminoindane
phenalkylamine derivatives
substituted
therapy
Prior art date
Application number
MX2014006004A
Other languages
English (en)
Inventor
Charles W Hutchins
Wilhelm Amberg
Udo Lange
Frauke Pohlki
Ernesto Santandrea
Original Assignee
Abbvie Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Deutschland filed Critical Abbvie Deutschland
Publication of MX2014006004A publication Critical patent/MX2014006004A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D305/04—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D305/08—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

La presente invención se refiere a derivados de aminobenzociclohepteno, aminotetralina, aminoindano y fenalcilamina n-sustituidas de fórmula (I), (II), (III) o (IV) o una sal aceptable fisiológicamente del mismo. La invención se refiere a composiciones farmacéuticas que comprenden tales derivados de aminobenzociclohepteno, aminotetralina, aminoindano y fenalcilamina n-sustituidas, y el uso de tales derivados de aminobenzociclohepteno, aminotetralina, aminoindano y fenalcilamina n-sustituidas con propósitos terapéuticos. Los derivados de aminobenzociclohepteno, aminotetralina, aminoindano y fenalcilamina n-sustituidas son inhibidores de GIyT1.
MX2014006004A 2011-11-18 2012-11-19 Derivados de aminobenzociclohepteno, aminotetralina, aminoindano y fenalcilamina n-sustituidas, composiciones farmaceuticas que los contienen, y su uso en terapia. MX2014006004A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161561653P 2011-11-18 2011-11-18
US201261597887P 2012-02-13 2012-02-13
PCT/EP2012/072950 WO2013072520A1 (en) 2011-11-18 2012-11-19 N-substituted aminobenzocycloheptene, aminotetraline, aminoindane and phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy

Publications (1)

Publication Number Publication Date
MX2014006004A true MX2014006004A (es) 2015-04-16

Family

ID=47226141

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014006004A MX2014006004A (es) 2011-11-18 2012-11-19 Derivados de aminobenzociclohepteno, aminotetralina, aminoindano y fenalcilamina n-sustituidas, composiciones farmaceuticas que los contienen, y su uso en terapia.

Country Status (7)

Country Link
US (1) US8846741B2 (es)
EP (1) EP2780328A1 (es)
JP (1) JP2014533675A (es)
CN (1) CN104011028A (es)
CA (1) CA2853254A1 (es)
MX (1) MX2014006004A (es)
WO (1) WO2013072520A1 (es)

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WO2015055771A1 (en) 2013-10-17 2015-04-23 AbbVie Deutschland GmbH & Co. KG Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy
AU2014336153A1 (en) 2013-10-17 2016-04-28 AbbVie Deutschland GmbH & Co. KG Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy
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US20130131132A1 (en) 2013-05-23
WO2013072520A1 (en) 2013-05-23
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JP2014533675A (ja) 2014-12-15
CA2853254A1 (en) 2013-05-23
EP2780328A1 (en) 2014-09-24

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