ATE359256T1 - Verfahren zur herstellung von (2r)-2- propyloktansäure - Google Patents
Verfahren zur herstellung von (2r)-2- propyloktansäureInfo
- Publication number
- ATE359256T1 ATE359256T1 AT00904007T AT00904007T ATE359256T1 AT E359256 T1 ATE359256 T1 AT E359256T1 AT 00904007 T AT00904007 T AT 00904007T AT 00904007 T AT00904007 T AT 00904007T AT E359256 T1 ATE359256 T1 AT E359256T1
- Authority
- AT
- Austria
- Prior art keywords
- acid
- propyloctic
- producing
- propyloctanoic
- octanoic acid
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- YCYMCMYLORLIJX-SNVBAGLBSA-N (2r)-2-propyloctanoic acid Chemical compound CCCCCC[C@H](C(O)=O)CCC YCYMCMYLORLIJX-SNVBAGLBSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- RXAINMDCYOMAHC-SNVBAGLBSA-N (2s)-2-prop-2-enyloctanoic acid Chemical compound CCCCCC[C@H](C(O)=O)CC=C RXAINMDCYOMAHC-SNVBAGLBSA-N 0.000 abstract 1
- DUQSBRQHALCSLC-SNVBAGLBSA-N (2s)-2-prop-2-ynyloctanoic acid Chemical compound CCCCCC[C@H](C(O)=O)CC#C DUQSBRQHALCSLC-SNVBAGLBSA-N 0.000 abstract 1
- 238000006317 isomerization reaction Methods 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/36—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by hydrogenation of carbon-to-carbon unsaturated bonds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
- B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
- B01J23/42—Platinum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J21/00—Catalysts comprising the elements, oxides, or hydroxides of magnesium, boron, aluminium, carbon, silicon, titanium, zirconium, or hafnium
- B01J21/18—Carbon
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Materials Engineering (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3975899 | 1999-02-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE359256T1 true ATE359256T1 (de) | 2007-05-15 |
Family
ID=12561862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00904007T ATE359256T1 (de) | 1999-02-18 | 2000-02-17 | Verfahren zur herstellung von (2r)-2- propyloktansäure |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6608221B1 (de) |
| EP (3) | EP1721882A1 (de) |
| JP (2) | JP4752989B2 (de) |
| KR (1) | KR100666423B1 (de) |
| CN (4) | CN100430364C (de) |
| AT (1) | ATE359256T1 (de) |
| AU (1) | AU776927B2 (de) |
| BR (1) | BR0008261A (de) |
| CA (1) | CA2364308C (de) |
| DE (1) | DE60034316T2 (de) |
| ES (1) | ES2283287T3 (de) |
| HU (1) | HUP0200358A3 (de) |
| MX (1) | MXPA01008241A (de) |
| NO (1) | NO20013971L (de) |
| NZ (1) | NZ513569A (de) |
| RU (1) | RU2297406C2 (de) |
| TW (1) | TWI268921B (de) |
| WO (1) | WO2000048982A1 (de) |
| ZA (1) | ZA200106500B (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI268921B (en) * | 1999-02-18 | 2006-12-21 | Ono Pharmaceutical Co | A process for preparing (2R)-2-propyloctanoic acid |
| JP4178405B2 (ja) | 2001-07-18 | 2008-11-12 | 小野薬品工業株式会社 | 脳虚血疾患治療剤 |
| JP2005298334A (ja) * | 2001-12-19 | 2005-10-27 | Ono Pharmaceut Co Ltd | 新規な中間体化合物およびそれを用いる化合物の製造方法 |
| US7928143B2 (en) * | 2003-10-03 | 2011-04-19 | Ono Pharmaceutical Co., Ltd. | Method for preventing and/or treating neurodegenerative diseases |
| AU2004277826B2 (en) * | 2003-10-03 | 2010-05-27 | Ono Pharmaceutical Co., Ltd. | Drug containing (2R)-2-propyloctanoic acid as the active ingredient |
| EP1669066A4 (de) * | 2003-10-03 | 2009-04-29 | Ono Pharmaceutical Co | Infusionspräparat mit (2r)-2-propyloctansäure als wirkstoff |
| JP4730303B2 (ja) * | 2004-04-28 | 2011-07-20 | 小野薬品工業株式会社 | （２ｒ）−２−プロピルオクタン酸とアミンとからなる結晶 |
| AU2005306741A1 (en) * | 2004-11-16 | 2006-05-26 | Merck & Co., Inc. | Prodrugs of (2R)-2-propyloctanoic acid for treatment of stroke |
| WO2006075596A1 (ja) * | 2005-01-13 | 2006-07-20 | Kuraray Co., Ltd. | ２－アリルカルボン酸化合物の製造方法 |
| EP2266559A1 (de) | 2005-03-15 | 2010-12-29 | Ono Pharmaceutical Co., Ltd. | Therapeutischer Wirkstoff zur Behandlung von opthalmischen Erkrankungen |
| US8975298B2 (en) | 2005-06-27 | 2015-03-10 | Ono Pharmaceutical Co., Ltd. | Therapeutic agent for pain |
| CA2625341A1 (en) | 2005-10-18 | 2007-04-26 | Ono Pharmaceutical Co., Ltd. | Pharmaceutical for protection of motor nerve in patient with amyotrophic lateral sclerosis |
| WO2007072902A1 (ja) | 2005-12-22 | 2007-06-28 | Ono Pharmaceutical Co., Ltd. | 急性期脳梗塞治療剤 |
| US20090118542A1 (en) * | 2006-02-16 | 2009-05-07 | Shigeya Yamazaki | Process for Production of Optically Active Carboxlic Acid Compound |
| EP2015741A4 (de) * | 2006-05-04 | 2009-12-23 | Merck & Co Inc | Histondeacetylase-hemmer zur behandlung von neurodegeneration |
| CN102417445B (zh) * | 2011-11-05 | 2013-11-13 | 中国科学院山西煤炭化学研究所 | 一种由马来酸合成丁二酸的方法 |
| CN102675166B (zh) * | 2012-05-11 | 2014-03-26 | 山东齐都药业有限公司 | 用于制备2-丙基庚酸的新中间体、其制备方法及2-丙基庚酸的制备方法 |
| CN102786407B (zh) * | 2012-08-15 | 2014-04-16 | 湖北大学 | 一种制备(2r)-2-丙基辛酸的方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2317019A1 (de) | 1972-04-27 | 1973-11-08 | Upjohn Co | Neue 4,5-didehydro-prostaglandine |
| JPH0672123B2 (ja) * | 1986-08-21 | 1994-09-14 | セントラル硝子株式会社 | トリフルオロメチル基を有するシクロヘキサンカルボン酸の製造方法 |
| JP2868183B2 (ja) * | 1988-02-29 | 1999-03-10 | 株式式社三和化学研究所 | 光学活性を有する４−オキソ−１−ベンゾピラン−２−カルボン酸誘導体の製法、その合成用中間体並びに該中間体の製法 |
| US5202474A (en) * | 1989-06-22 | 1993-04-13 | Monsanto Company | Asymmetric catalytic hydrogenation of α-arylpropenoic acids |
| DK0632008T3 (da) | 1993-06-01 | 1998-09-23 | Ono Pharmaceutical Co | Pentansyrederivater |
| JP3032447B2 (ja) * | 1995-04-24 | 2000-04-17 | 小野薬品工業株式会社 | 光学活性な２−プロピルオクタン酸の製造方法 |
| JP3084345B2 (ja) * | 1995-04-26 | 2000-09-04 | 小野薬品工業株式会社 | 光学活性な２−プロピルオクタン酸の製造方法 |
| TW509672B (en) | 1998-05-12 | 2002-11-11 | Ono Pharmaceutical Co | Novel intermediate compounds and processes for the production of optical active octanoic acid derivatives |
| TWI268921B (en) * | 1999-02-18 | 2006-12-21 | Ono Pharmaceutical Co | A process for preparing (2R)-2-propyloctanoic acid |
| JP4730303B2 (ja) * | 2004-04-28 | 2011-07-20 | 小野薬品工業株式会社 | （２ｒ）−２−プロピルオクタン酸とアミンとからなる結晶 |
-
2000
- 2000-02-16 TW TW089102580A patent/TWI268921B/zh not_active IP Right Cessation
- 2000-02-17 EP EP06012510A patent/EP1721882A1/de not_active Withdrawn
- 2000-02-17 US US09/890,651 patent/US6608221B1/en not_active Expired - Fee Related
- 2000-02-17 BR BR0008261-9A patent/BR0008261A/pt not_active Application Discontinuation
- 2000-02-17 KR KR1020017010357A patent/KR100666423B1/ko not_active Expired - Fee Related
- 2000-02-17 CN CNB2004100927127A patent/CN100430364C/zh not_active Expired - Fee Related
- 2000-02-17 DE DE60034316T patent/DE60034316T2/de not_active Expired - Lifetime
- 2000-02-17 EP EP06012511A patent/EP1714956A1/de not_active Withdrawn
- 2000-02-17 ES ES00904007T patent/ES2283287T3/es not_active Expired - Lifetime
- 2000-02-17 WO PCT/JP2000/000900 patent/WO2000048982A1/ja not_active Ceased
- 2000-02-17 CN CNA2006100997275A patent/CN101100422A/zh active Pending
- 2000-02-17 EP EP00904007A patent/EP1153910B1/de not_active Expired - Lifetime
- 2000-02-17 RU RU2001125501/04A patent/RU2297406C2/ru active
- 2000-02-17 AU AU25730/00A patent/AU776927B2/en not_active Ceased
- 2000-02-17 CN CNA2006101002245A patent/CN1907938A/zh active Pending
- 2000-02-17 CA CA002364308A patent/CA2364308C/en not_active Expired - Fee Related
- 2000-02-17 CN CNB008040133A patent/CN1183082C/zh not_active Expired - Fee Related
- 2000-02-17 AT AT00904007T patent/ATE359256T1/de not_active IP Right Cessation
- 2000-02-17 MX MXPA01008241A patent/MXPA01008241A/es active IP Right Grant
- 2000-02-17 HU HU0200358A patent/HUP0200358A3/hu unknown
- 2000-02-17 NZ NZ513569A patent/NZ513569A/xx not_active IP Right Cessation
- 2000-02-17 JP JP2000599723A patent/JP4752989B2/ja not_active Expired - Fee Related
-
2001
- 2001-08-07 ZA ZA200106500A patent/ZA200106500B/en unknown
- 2001-08-15 NO NO20013971A patent/NO20013971L/no not_active Application Discontinuation
-
2010
- 2010-05-20 JP JP2010116000A patent/JP5343925B2/ja not_active Expired - Fee Related
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |