BR0008261A - Processo para preparação de ácido (2r)-propiloctanóico - Google Patents

Processo para preparação de ácido (2r)-propiloctanóico

Info

Publication number
BR0008261A
BR0008261A BR0008261-9A BR0008261A BR0008261A BR 0008261 A BR0008261 A BR 0008261A BR 0008261 A BR0008261 A BR 0008261A BR 0008261 A BR0008261 A BR 0008261A
Authority
BR
Brazil
Prior art keywords
acid
preparation
propyloctanoic acid
propyloctanoic
octanoic
Prior art date
Application number
BR0008261-9A
Other languages
English (en)
Inventor
Norikazu Toda
Kaoru Yamaguchi
Youichi Iguchi
Original Assignee
Ono Pharmaceutical Co
Tokyo Kasei Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co, Tokyo Kasei Kogyo Co Ltd filed Critical Ono Pharmaceutical Co
Publication of BR0008261A publication Critical patent/BR0008261A/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
    • B01J23/42—Platinum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J21/00—Catalysts comprising the elements, oxides, or hydroxides of magnesium, boron, aluminium, carbon, silicon, titanium, zirconium, or hafnium
    • B01J21/18—Carbon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/36—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by hydrogenation of carbon-to-carbon unsaturated bonds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)

Abstract

Patente de Invenção: "PROCESSO PARA PREPARAçãO DE áCIDO (2R)-PROPILOCTANóICO". Trata-se de um processo para preparar ácido (2R)-2-propiloctanóico caracterizado por submissão do ácido (2S)-2-(2-propinil)octanóico ou ácido (2S)-2-(2-propenil)octanóico à redução usando platina em carbono. Este processo confere ácido (2R)-2-propiloctanóico com alto grau de pureza óptica sem recorrer à isomerização.
BR0008261-9A 1999-02-18 2000-02-17 Processo para preparação de ácido (2r)-propiloctanóico BR0008261A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3975899 1999-02-18
PCT/JP2000/000900 WO2000048982A1 (fr) 1999-02-18 2000-02-17 Procede de preparation d'acide (2r)-2-propyloctanoique

Publications (1)

Publication Number Publication Date
BR0008261A true BR0008261A (pt) 2002-01-15

Family

ID=12561862

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0008261-9A BR0008261A (pt) 1999-02-18 2000-02-17 Processo para preparação de ácido (2r)-propiloctanóico

Country Status (19)

Country Link
US (1) US6608221B1 (pt)
EP (3) EP1153910B1 (pt)
JP (2) JP4752989B2 (pt)
KR (1) KR100666423B1 (pt)
CN (4) CN1183082C (pt)
AT (1) ATE359256T1 (pt)
AU (1) AU776927B2 (pt)
BR (1) BR0008261A (pt)
CA (1) CA2364308C (pt)
DE (1) DE60034316T2 (pt)
ES (1) ES2283287T3 (pt)
HU (1) HUP0200358A3 (pt)
MX (1) MXPA01008241A (pt)
NO (1) NO20013971L (pt)
NZ (1) NZ513569A (pt)
RU (1) RU2297406C2 (pt)
TW (1) TWI268921B (pt)
WO (1) WO2000048982A1 (pt)
ZA (1) ZA200106500B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI268921B (en) * 1999-02-18 2006-12-21 Ono Pharmaceutical Co A process for preparing (2R)-2-propyloctanoic acid
US20040176347A1 (en) 2001-07-18 2004-09-09 Kaneyoshi Honjo Agent for treatment of cerebral ischemic diseases
JP2005298334A (ja) * 2001-12-19 2005-10-27 Ono Pharmaceut Co Ltd 新規な中間体化合物およびそれを用いる化合物の製造方法
US7928143B2 (en) * 2003-10-03 2011-04-19 Ono Pharmaceutical Co., Ltd. Method for preventing and/or treating neurodegenerative diseases
CN1889941A (zh) * 2003-10-03 2007-01-03 小野药品工业株式会社 包含(2r)－2－丙基辛酸作为活性成分的输液制剂
TW200519080A (en) * 2003-10-03 2005-06-16 Ono Pharmaceutical Co Agent containinf (2R)-2-propyloctanic acid as effective component
JP4730303B2 (ja) * 2004-04-28 2011-07-20 小野薬品工業株式会社 （２ｒ）−２−プロピルオクタン酸とアミンとからなる結晶
EP1814838A4 (en) * 2004-11-16 2010-03-17 Merck Sharp & Dohme PRODRUGS FROM (2R) -2-PROPYLOCTANIC ACIDS FOR THE TREATMENT OF APOPLEXIA
JPWO2006075596A1 (ja) * 2005-01-13 2008-06-12 株式会社クラレ ２−アリルカルボン酸化合物の製造方法
EP2266559A1 (en) 2005-03-15 2010-12-29 Ono Pharmaceutical Co., Ltd. Therapeutic agent for ophthalmic disease
EP2465499A3 (en) 2005-06-27 2013-02-13 Ono Pharmaceutical Co., Ltd. Therapeutic agent for treating pain
RU2008119454A (ru) 2005-10-18 2009-11-27 Оно Фармасьютикал Ко., Лтд. (Jp) Лекарственное средство для защиты моторного нейрона у пациентов с боковым амиотрофическим склерозом
EP1974727A4 (en) 2005-12-22 2009-12-09 Ono Pharmaceutical Co THERAPEUTIC AGENT AGAINST ACUTE CEREBRALINE INFARC
WO2007094404A1 (ja) * 2006-02-16 2007-08-23 Sumitomo Chemical Company, Limited 光学活性カルボン酸化合物の製造方法
US20090325862A1 (en) * 2006-05-04 2009-12-31 Christian Steinkuhler Histone Deacetylase Inhibitors for the Treatment of Neurodegeneration
CN102417445B (zh) * 2011-11-05 2013-11-13 中国科学院山西煤炭化学研究所 一种由马来酸合成丁二酸的方法
CN102675166B (zh) * 2012-05-11 2014-03-26 山东齐都药业有限公司 用于制备2-丙基庚酸的新中间体、其制备方法及2-丙基庚酸的制备方法
CN102786407B (zh) * 2012-08-15 2014-04-16 湖北大学 一种制备(2r)-2-丙基辛酸的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2317019A1 (de) 1972-04-27 1973-11-08 Upjohn Co Neue 4,5-didehydro-prostaglandine
JPH0672123B2 (ja) 1986-08-21 1994-09-14 セントラル硝子株式会社 トリフルオロメチル基を有するシクロヘキサンカルボン酸の製造方法
JP2868183B2 (ja) * 1988-02-29 1999-03-10 株式式社三和化学研究所 光学活性を有する４−オキソ−１−ベンゾピラン−２−カルボン酸誘導体の製法、その合成用中間体並びに該中間体の製法
ATE163006T1 (de) 1993-06-01 1998-02-15 Ono Pharmaceutical Co Pentansäurederivate
JP3032447B2 (ja) * 1995-04-24 2000-04-17 小野薬品工業株式会社 光学活性な２−プロピルオクタン酸の製造方法
JP3084345B2 (ja) * 1995-04-26 2000-09-04 小野薬品工業株式会社 光学活性な２−プロピルオクタン酸の製造方法
TW509672B (en) * 1998-05-12 2002-11-11 Ono Pharmaceutical Co Novel intermediate compounds and processes for the production of optical active octanoic acid derivatives
TWI268921B (en) * 1999-02-18 2006-12-21 Ono Pharmaceutical Co A process for preparing (2R)-2-propyloctanoic acid
JP4730303B2 (ja) * 2004-04-28 2011-07-20 小野薬品工業株式会社 （２ｒ）−２−プロピルオクタン酸とアミンとからなる結晶

Also Published As

Publication number Publication date
EP1153910A1 (en) 2001-11-14
RU2297406C2 (ru) 2007-04-20
NZ513569A (en) 2003-01-31
EP1721882A1 (en) 2006-11-15
JP4752989B2 (ja) 2011-08-17
CN100430364C (zh) 2008-11-05
CN1636957A (zh) 2005-07-13
CA2364308C (en) 2010-02-02
CN101100422A (zh) 2008-01-09
TWI268921B (en) 2006-12-21
RU2001125501A (ru) 2004-02-20
HUP0200358A2 (hu) 2002-05-29
NO20013971D0 (no) 2001-08-15
AU2573000A (en) 2000-09-04
HUP0200358A3 (en) 2003-03-28
CN1907938A (zh) 2007-02-07
EP1714956A1 (en) 2006-10-25
JP5343925B2 (ja) 2013-11-13
WO2000048982A1 (fr) 2000-08-24
ATE359256T1 (de) 2007-05-15
KR20010102161A (ko) 2001-11-15
CN1341091A (zh) 2002-03-20
CN1183082C (zh) 2005-01-05
KR100666423B1 (ko) 2007-01-11
ES2283287T3 (es) 2007-11-01
ZA200106500B (en) 2003-02-07
EP1153910A4 (en) 2002-08-07
MXPA01008241A (es) 2002-08-30
DE60034316D1 (de) 2007-05-24
EP1153910B1 (en) 2007-04-11
CA2364308A1 (en) 2000-08-24
AU776927B2 (en) 2004-09-23
DE60034316T2 (de) 2008-01-03
US6608221B1 (en) 2003-08-19
NO20013971L (no) 2001-08-15
JP2010248198A (ja) 2010-11-04

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: ONO PHARMACEUTICAL CO., LTD. (JP)

Free format text: TRANSFERIDO DE: TOKYO KASEI KOGYO CO., LTD.

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O E 13 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.