DE60034316D1 - Verfahren zur herstellung von (2r)-2-propyloktansäure - Google Patents

Verfahren zur herstellung von (2r)-2-propyloktansäure

Info

Publication number
DE60034316D1
DE60034316D1 DE60034316T DE60034316T DE60034316D1 DE 60034316 D1 DE60034316 D1 DE 60034316D1 DE 60034316 T DE60034316 T DE 60034316T DE 60034316 T DE60034316 T DE 60034316T DE 60034316 D1 DE60034316 D1 DE 60034316D1
Authority
DE
Germany
Prior art keywords
acid
propylectanic
preparing
propyloctanoic
octanoic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60034316T
Other languages
English (en)
Other versions
DE60034316T2 (de
Inventor
Norikazu Toda
Kaoru Yamaguchi
Youichi Iguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE60034316D1 publication Critical patent/DE60034316D1/de
Publication of DE60034316T2 publication Critical patent/DE60034316T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
    • B01J23/42—Platinum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J21/00—Catalysts comprising the elements, oxides, or hydroxides of magnesium, boron, aluminium, carbon, silicon, titanium, zirconium, or hafnium
    • B01J21/18—Carbon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/36—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by hydrogenation of carbon-to-carbon unsaturated bonds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
DE60034316T 1999-02-18 2000-02-17 Verfahren zur herstellung von (2r)-2-propyloktansäure Expired - Lifetime DE60034316T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP3975899 1999-02-18
JP3975899 1999-02-18
PCT/JP2000/000900 WO2000048982A1 (fr) 1999-02-18 2000-02-17 Procede de preparation d'acide (2r)-2-propyloctanoique

Publications (2)

Publication Number Publication Date
DE60034316D1 true DE60034316D1 (de) 2007-05-24
DE60034316T2 DE60034316T2 (de) 2008-01-03

Family

ID=12561862

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60034316T Expired - Lifetime DE60034316T2 (de) 1999-02-18 2000-02-17 Verfahren zur herstellung von (2r)-2-propyloktansäure

Country Status (19)

Country Link
US (1) US6608221B1 (de)
EP (3) EP1153910B1 (de)
JP (2) JP4752989B2 (de)
KR (1) KR100666423B1 (de)
CN (4) CN101100422A (de)
AT (1) ATE359256T1 (de)
AU (1) AU776927B2 (de)
BR (1) BR0008261A (de)
CA (1) CA2364308C (de)
DE (1) DE60034316T2 (de)
ES (1) ES2283287T3 (de)
HU (1) HUP0200358A3 (de)
MX (1) MXPA01008241A (de)
NO (1) NO20013971D0 (de)
NZ (1) NZ513569A (de)
RU (1) RU2297406C2 (de)
TW (1) TWI268921B (de)
WO (1) WO2000048982A1 (de)
ZA (1) ZA200106500B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI268921B (en) * 1999-02-18 2006-12-21 Ono Pharmaceutical Co A process for preparing (2R)-2-propyloctanoic acid
US20040176347A1 (en) 2001-07-18 2004-09-09 Kaneyoshi Honjo Agent for treatment of cerebral ischemic diseases
JP2005298334A (ja) * 2001-12-19 2005-10-27 Ono Pharmaceut Co Ltd 新規な中間体化合物およびそれを用いる化合物の製造方法
CN1889941A (zh) * 2003-10-03 2007-01-03 小野药品工业株式会社 包含(2r)－2－丙基辛酸作为活性成分的输液制剂
US7928143B2 (en) * 2003-10-03 2011-04-19 Ono Pharmaceutical Co., Ltd. Method for preventing and/or treating neurodegenerative diseases
CA2540670A1 (en) * 2003-10-03 2005-04-14 Ono Pharmaceutical Co., Ltd. Drug containing (2r)-2-propyloctanoic acid as the active ingredient
EP1741697B1 (de) * 2004-04-28 2012-12-19 Ono Pharmaceutical Co., Ltd. Kristall, enthaltend (2r)-2-propyloctansäure und dibenzylamin
CN101056842A (zh) * 2004-11-16 2007-10-17 默克公司 治疗中风的(2r)－2－丙基辛酸前药
JPWO2006075596A1 (ja) * 2005-01-13 2008-06-12 株式会社クラレ ２−アリルカルボン酸化合物の製造方法
JPWO2006098292A1 (ja) 2005-03-15 2008-08-21 小野薬品工業株式会社 眼疾患治療剤
EP1900363A4 (de) 2005-06-27 2010-01-13 Ono Pharmaceutical Co Therapeutisches mittel gegen schmerzen
AU2006305309A1 (en) 2005-10-18 2007-04-26 Ono Pharmaceutical Co., Ltd. Pharmaceutical for protection of motor nerve in patient with amyotrophic lateral sclerosis
JPWO2007072902A1 (ja) 2005-12-22 2009-06-04 小野薬品工業株式会社 急性期脳梗塞治療剤
US20090118542A1 (en) * 2006-02-16 2009-05-07 Shigeya Yamazaki Process for Production of Optically Active Carboxlic Acid Compound
EP2015741A4 (de) * 2006-05-04 2009-12-23 Merck & Co Inc Histondeacetylase-hemmer zur behandlung von neurodegeneration
CN102417445B (zh) * 2011-11-05 2013-11-13 中国科学院山西煤炭化学研究所 一种由马来酸合成丁二酸的方法
CN102675166B (zh) * 2012-05-11 2014-03-26 山东齐都药业有限公司 用于制备2-丙基庚酸的新中间体、其制备方法及2-丙基庚酸的制备方法
CN102786407B (zh) * 2012-08-15 2014-04-16 湖北大学 一种制备(2r)-2-丙基辛酸的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2317019A1 (de) * 1972-04-27 1973-11-08 Upjohn Co Neue 4,5-didehydro-prostaglandine
JPH0672123B2 (ja) * 1986-08-21 1994-09-14 セントラル硝子株式会社 トリフルオロメチル基を有するシクロヘキサンカルボン酸の製造方法
JP2868183B2 (ja) * 1988-02-29 1999-03-10 株式式社三和化学研究所 光学活性を有する４−オキソ−１−ベンゾピラン−２−カルボン酸誘導体の製法、その合成用中間体並びに該中間体の製法
EP0632008B1 (de) * 1993-06-01 1998-02-04 Ono Pharmaceutical Co., Ltd. Pentansäurederivate
JP3032447B2 (ja) * 1995-04-24 2000-04-17 小野薬品工業株式会社 光学活性な２−プロピルオクタン酸の製造方法
JP3084345B2 (ja) * 1995-04-26 2000-09-04 小野薬品工業株式会社 光学活性な２−プロピルオクタン酸の製造方法
TW509672B (en) 1998-05-12 2002-11-11 Ono Pharmaceutical Co Novel intermediate compounds and processes for the production of optical active octanoic acid derivatives
TWI268921B (en) * 1999-02-18 2006-12-21 Ono Pharmaceutical Co A process for preparing (2R)-2-propyloctanoic acid
EP1741697B1 (de) * 2004-04-28 2012-12-19 Ono Pharmaceutical Co., Ltd. Kristall, enthaltend (2r)-2-propyloctansäure und dibenzylamin

Also Published As

Publication number Publication date
MXPA01008241A (es) 2002-08-30
ES2283287T3 (es) 2007-11-01
HUP0200358A3 (en) 2003-03-28
AU776927B2 (en) 2004-09-23
CN100430364C (zh) 2008-11-05
BR0008261A (pt) 2002-01-15
EP1153910B1 (de) 2007-04-11
EP1721882A1 (de) 2006-11-15
EP1153910A1 (de) 2001-11-14
HUP0200358A2 (hu) 2002-05-29
US6608221B1 (en) 2003-08-19
TWI268921B (en) 2006-12-21
KR100666423B1 (ko) 2007-01-11
CN1341091A (zh) 2002-03-20
AU2573000A (en) 2000-09-04
EP1714956A1 (de) 2006-10-25
ZA200106500B (en) 2003-02-07
JP5343925B2 (ja) 2013-11-13
CA2364308A1 (en) 2000-08-24
JP4752989B2 (ja) 2011-08-17
CN101100422A (zh) 2008-01-09
DE60034316T2 (de) 2008-01-03
CN1636957A (zh) 2005-07-13
CA2364308C (en) 2010-02-02
NO20013971L (no) 2001-08-15
RU2001125501A (ru) 2004-02-20
CN1183082C (zh) 2005-01-05
ATE359256T1 (de) 2007-05-15
KR20010102161A (ko) 2001-11-15
RU2297406C2 (ru) 2007-04-20
JP2010248198A (ja) 2010-11-04
CN1907938A (zh) 2007-02-07
NO20013971D0 (no) 2001-08-15
NZ513569A (en) 2003-01-31
EP1153910A4 (de) 2002-08-07
WO2000048982A1 (fr) 2000-08-24

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