ATE322912T1 - Radiomarkierte pyrimidinnukleoside zur diagnose von gewebe-reproduzierender aktivität - Google Patents
Radiomarkierte pyrimidinnukleoside zur diagnose von gewebe-reproduzierender aktivitätInfo
- Publication number
- ATE322912T1 ATE322912T1 AT02716326T AT02716326T ATE322912T1 AT E322912 T1 ATE322912 T1 AT E322912T1 AT 02716326 T AT02716326 T AT 02716326T AT 02716326 T AT02716326 T AT 02716326T AT E322912 T1 ATE322912 T1 AT E322912T1
- Authority
- AT
- Austria
- Prior art keywords
- denotes
- radiom
- substituent
- pyrimidine nucleosides
- denotes hydrogen
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Optics & Photonics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001014954 | 2001-01-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE322912T1 true ATE322912T1 (de) | 2006-04-15 |
Family
ID=18881578
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02716326T ATE322912T1 (de) | 2001-01-23 | 2002-01-22 | Radiomarkierte pyrimidinnukleoside zur diagnose von gewebe-reproduzierender aktivität |
Country Status (14)
Country | Link |
---|---|
US (2) | US7045115B2 (de) |
EP (1) | EP1270017B1 (de) |
JP (1) | JP4210118B2 (de) |
KR (1) | KR100867729B1 (de) |
CN (1) | CN100400107C (de) |
AT (1) | ATE322912T1 (de) |
AU (1) | AU2002226690B2 (de) |
CA (1) | CA2402991C (de) |
DE (1) | DE60210538T2 (de) |
HK (1) | HK1059396A1 (de) |
NO (1) | NO328812B1 (de) |
NZ (1) | NZ520934A (de) |
TW (1) | TWI247609B (de) |
WO (1) | WO2002058740A1 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7344702B2 (en) | 2004-02-13 | 2008-03-18 | Bristol-Myers Squibb Pharma Company | Contrast agents for myocardial perfusion imaging |
EP1673353A4 (de) * | 2003-09-05 | 2007-03-28 | Einstein Coll Med | Übergangszustandstruktur und inhibitoren von thymidinphosphorylase |
WO2005027962A1 (en) * | 2003-09-18 | 2005-03-31 | Isis Pharmaceuticals, Inc. | 4’-thionucleosides and oligomeric compounds |
US7485283B2 (en) * | 2004-04-28 | 2009-02-03 | Lantheus Medical Imaging | Contrast agents for myocardial perfusion imaging |
JP4841231B2 (ja) * | 2005-11-07 | 2011-12-21 | 日本メジフィジックス株式会社 | 組織増殖能診断用薬剤 |
CA2649182C (en) | 2006-04-07 | 2018-01-02 | The Board Of Regents Of The University Of Texas System | Methods and compositions related to adenoassociated virus-phage particles |
US7928210B2 (en) | 2007-03-01 | 2011-04-19 | Siemens Medical Solutions Usa, Inc. | Nucleoside based proliferation imaging markers |
EP2155231B1 (de) * | 2007-04-10 | 2012-08-08 | The Johns Hopkins University | Bilddarstellung und behandlung von virus-assoziierten tumoren |
CA2967254C (en) * | 2008-02-29 | 2019-03-26 | Lantheus Medical Imaging, Inc. | Contrast agents for applications including imaging cancer |
GB0815831D0 (en) * | 2008-09-01 | 2008-10-08 | Imp Innovations Ltd | Compounds |
EP2419096B1 (de) | 2009-04-15 | 2019-11-13 | Lantheus Medical Imaging, Inc. | Stabilisierung von radiopharmazeutischen zusammensetzungen mit ascorbinsäure |
JP6092628B2 (ja) | 2010-02-08 | 2017-03-08 | ランセウス メディカル イメージング, インコーポレイテッド | 造影剤およびその中間体を合成するための方法および装置 |
US8835612B2 (en) * | 2010-10-09 | 2014-09-16 | Fabio Polato | Isolation of phosphoproteins, glycoproteins and fragments thereof |
JP5794521B2 (ja) * | 2011-03-29 | 2015-10-14 | 国立大学法人福井大学 | アポトーシス誘導剤 |
SG11201406080VA (en) | 2012-03-28 | 2014-11-27 | Fujifilm Corp | SALT OF 1-(2-DEOXY-2-FLUORO-4-THIO-β-D-ARABINOFURANOSYL)CYTOSINE |
AU2013203000B9 (en) | 2012-08-10 | 2017-02-02 | Lantheus Medical Imaging, Inc. | Compositions, methods, and systems for the synthesis and use of imaging agents |
RU2633355C2 (ru) * | 2012-08-13 | 2017-10-12 | Фуджифилм Корпорэйшн | СИНТЕТИЧЕСКОЕ ПРОМЕЖУТОЧНОЕ СОЕДИНЕНИЕ 1-(2-ДЕЗОКСИ-2-ФТОР-4-ТИО-β-D-АРАБИНОФУРАНОЗИЛ)ЦИТОЗИНА, СИНТЕТИЧЕСКОЕ ПРОМЕЖУТОЧНОЕ СОЕДИНЕНИЕ ТИОНУКЛЕОЗИДА И СПОСОБ ИХ ПОЛУЧЕНИЯ |
JP2014062054A (ja) * | 2012-09-20 | 2014-04-10 | Gyoseiin Genshino Iinkai Kakuno Kenkyusho | よう素−123標記チミン類似物[123I]−IaraUのプローブ |
JP6351107B2 (ja) * | 2014-02-18 | 2018-07-04 | 富士フイルム株式会社 | チオラン骨格型糖化合物の製造方法およびチオラン骨格型糖化合物 |
TWI678373B (zh) | 2014-10-31 | 2019-12-01 | 日商富士軟片股份有限公司 | 硫代核苷衍生物或其鹽及醫藥組合物 |
WO2018043530A1 (ja) | 2016-08-31 | 2018-03-08 | 富士フイルム株式会社 | 抗腫瘍剤、抗腫瘍効果増強剤及び抗腫瘍用キット |
CA3089728C (en) | 2018-01-29 | 2023-01-10 | Fujifilm Corporation | Antitumor agent for biliary tract cancer and method for treating biliary tract cancer |
CN113683648A (zh) * | 2021-08-26 | 2021-11-23 | 上海皓鸿生物医药科技有限公司 | 一种2’-氟-2’-脱氧尿苷的合成方法及其中间体 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE74701B1 (en) * | 1989-10-04 | 1997-07-30 | Univ Birmingham | Further antiviral pyrimidine nucleosides |
US5077034A (en) | 1990-03-30 | 1991-12-31 | The President And Fellows Of Harvard College | Treatment of tumors with 5-radioiodo-2'-deoxyuridine |
US5248771A (en) | 1991-06-26 | 1993-09-28 | Triumf | Process for preparing no-carrier-added radiohalogenated vinyl nucleosides |
GB9421223D0 (en) | 1994-10-21 | 1994-12-07 | Univ Alberta | Tissue imaging in gene therapy |
US5574148A (en) | 1995-02-02 | 1996-11-12 | President U Fellows Of Harvard College | Rapid synthesis of radiolabeled pyrimidine nucleosides or nucleotides |
US5703056A (en) * | 1995-03-15 | 1997-12-30 | Sloan-Kettering Institute For Cancer Research | Non-invasive imaging of gene transfer |
US5720935A (en) * | 1995-06-09 | 1998-02-24 | President & Fellows Of Harvard College | Rapid synthesis of radiolabeled pyrimidine nucleosides or nucleotides from stannyl precursors |
WO1996041646A2 (en) | 1995-06-13 | 1996-12-27 | Dyer, Alison, Margaret | Pharmaceutical compositions containing lornoxicam and cyclodextrin |
US6331287B1 (en) | 1995-08-23 | 2001-12-18 | University Advanced Bio-Imaging Associates | 2′-deoxy-2′-fluoro-d-arabinofuranosyl pyrimidine nucleoside |
WO2001005439A1 (en) * | 1999-07-14 | 2001-01-25 | President And Fellows Of Harvard College | Radiodetection and therapy of aberrant cell proliferation |
KR200188038Y1 (ko) | 2000-01-24 | 2000-07-15 | 이정진 | 전자파 피해가 감소되는 안테나 구조를 가진 휴대폰. |
-
2002
- 2002-01-18 TW TW091100830A patent/TWI247609B/zh not_active IP Right Cessation
- 2002-01-22 EP EP02716326A patent/EP1270017B1/de not_active Expired - Lifetime
- 2002-01-22 AU AU2002226690A patent/AU2002226690B2/en not_active Ceased
- 2002-01-22 DE DE60210538T patent/DE60210538T2/de not_active Expired - Lifetime
- 2002-01-22 CA CA002402991A patent/CA2402991C/en not_active Expired - Fee Related
- 2002-01-22 KR KR1020027012275A patent/KR100867729B1/ko active IP Right Grant
- 2002-01-22 JP JP2002559074A patent/JP4210118B2/ja not_active Expired - Lifetime
- 2002-01-22 NZ NZ52093402A patent/NZ520934A/xx not_active IP Right Cessation
- 2002-01-22 WO PCT/JP2002/000408 patent/WO2002058740A1/ja active IP Right Grant
- 2002-01-22 AT AT02716326T patent/ATE322912T1/de not_active IP Right Cessation
- 2002-01-22 CN CNB028001540A patent/CN100400107C/zh not_active Expired - Fee Related
- 2002-01-22 US US10/239,355 patent/US7045115B2/en not_active Expired - Lifetime
- 2002-09-10 NO NO20024324A patent/NO328812B1/no not_active IP Right Cessation
-
2004
- 2004-04-01 HK HK04102385.5A patent/HK1059396A1/xx not_active IP Right Cessation
- 2004-11-16 US US10/988,657 patent/US7118731B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
TWI247609B (en) | 2006-01-21 |
US7118731B2 (en) | 2006-10-10 |
NZ520934A (en) | 2004-12-24 |
CN100400107C (zh) | 2008-07-09 |
WO2002058740A1 (fr) | 2002-08-01 |
DE60210538T2 (de) | 2006-10-05 |
DE60210538D1 (de) | 2006-05-24 |
EP1270017B1 (de) | 2006-04-12 |
US7045115B2 (en) | 2006-05-16 |
US20050129611A1 (en) | 2005-06-16 |
CA2402991A1 (en) | 2002-08-01 |
CA2402991C (en) | 2009-06-23 |
AU2002226690B2 (en) | 2006-07-13 |
NO20024324D0 (no) | 2002-09-10 |
US20030124054A1 (en) | 2003-07-03 |
CN1455683A (zh) | 2003-11-12 |
JP4210118B2 (ja) | 2009-01-14 |
HK1059396A1 (en) | 2004-07-02 |
NO328812B1 (no) | 2010-05-18 |
JPWO2002058740A1 (ja) | 2004-05-27 |
EP1270017A4 (de) | 2004-04-28 |
KR100867729B1 (ko) | 2008-11-10 |
NO20024324L (no) | 2002-11-07 |
EP1270017A1 (de) | 2003-01-02 |
KR20020084212A (ko) | 2002-11-04 |
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Legal Events
Date | Code | Title | Description |
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |