ATE314102T1 - Verwendung einer kollagenmembrane zur herstellung eines implantates für gesteuerte geweberegeneration - Google Patents

Verwendung einer kollagenmembrane zur herstellung eines implantates für gesteuerte geweberegeneration

Info

Publication number
ATE314102T1
ATE314102T1 AT95904642T AT95904642T ATE314102T1 AT E314102 T1 ATE314102 T1 AT E314102T1 AT 95904642 T AT95904642 T AT 95904642T AT 95904642 T AT95904642 T AT 95904642T AT E314102 T1 ATE314102 T1 AT E314102T1
Authority
AT
Austria
Prior art keywords
membrane
implant
collagen membrane
tissue regeneration
produce
Prior art date
Application number
AT95904642T
Other languages
English (en)
Inventor
Peter Geistlich
Zdenek Eckmayer
Philip Boyne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10748458&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE314102(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Application granted granted Critical
Publication of ATE314102T1 publication Critical patent/ATE314102T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A61L15/325—Collagen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/34—Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28—Polysaccharides or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/005—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/043—Proteins; Polypeptides; Degradation products thereof
    • A61L31/044—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Nutrition Science (AREA)
  • Cardiology (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Physiology (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
AT95904642T 1994-01-06 1995-01-04 Verwendung einer kollagenmembrane zur herstellung eines implantates für gesteuerte geweberegeneration ATE314102T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9400163A GB9400163D0 (en) 1994-01-06 1994-01-06 Membrane
PCT/GB1995/000008 WO1995018638A1 (en) 1994-01-06 1995-01-04 Membrane

Publications (1)

Publication Number Publication Date
ATE314102T1 true ATE314102T1 (de) 2006-01-15

Family

ID=10748458

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95904642T ATE314102T1 (de) 1994-01-06 1995-01-04 Verwendung einer kollagenmembrane zur herstellung eines implantates für gesteuerte geweberegeneration

Country Status (9)

Country Link
US (1) US5837278A (de)
EP (2) EP0738161B1 (de)
JP (1) JP3577083B2 (de)
AT (1) ATE314102T1 (de)
CA (1) CA2180659C (de)
DE (1) DE69534713T2 (de)
ES (2) ES2255707T3 (de)
GB (1) GB9400163D0 (de)
WO (1) WO1995018638A1 (de)

Families Citing this family (158)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9503492D0 (en) * 1995-02-22 1995-04-12 Ed Geistlich S Hne A G F R Che Chemical product
US7141072B2 (en) * 1998-10-05 2006-11-28 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method for promoting regeneration of surface cartilage in a damaged joint using multi-layer covering
US20050186673A1 (en) * 1995-02-22 2005-08-25 Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie Collagen carrier of therapeutic genetic material, and method
GB9721585D0 (en) 1997-10-10 1997-12-10 Geistlich Soehne Ag Chemical product
JPH09122227A (ja) * 1995-10-31 1997-05-13 Bio Eng Lab:Kk 医用材料およびその製造方法
JPH09122225A (ja) * 1995-10-31 1997-05-13 Bio Eng Lab:Kk 医用材料の原料膜材およびその製造方法
JP3476631B2 (ja) * 1995-12-21 2003-12-10 株式会社アムニオテック ヒト由来の天然コラーゲン膜からなる医用材料
US6352558B1 (en) 1996-02-22 2002-03-05 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method for promoting regeneration of surface cartilage in a damage joint
DE19654884C2 (de) * 1996-03-04 1999-07-29 Kirsch Axel Formkörper
US5940807A (en) * 1996-05-24 1999-08-17 Purcell; Daniel S. Automated and independently accessible inventory information exchange system
US20020173806A1 (en) * 1996-08-30 2002-11-21 Verigen Transplantation Service International (Vtsi) Ag Method for autologous transplantation
US20060025786A1 (en) * 1996-08-30 2006-02-02 Verigen Transplantation Service International (Vtsi) Ag Method for autologous transplantation
US6569172B2 (en) * 1996-08-30 2003-05-27 Verigen Transplantation Service International (Vtsi) Method, instruments, and kit for autologous transplantation
US5989269A (en) 1996-08-30 1999-11-23 Vts Holdings L.L.C. Method, instruments and kit for autologous transplantation
TW501934B (en) * 1996-11-20 2002-09-11 Tapic Int Co Ltd Collagen material and process for making the same
GB9716219D0 (en) * 1997-07-31 1997-10-08 Geistlich Soehne Ag Prevention of metastases
US8304390B2 (en) 1997-07-31 2012-11-06 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method of treatment for preventing or reducing tumor growth in the liver of patient
FR2766717B1 (fr) * 1997-08-01 2000-06-09 Cogent Sarl Prothese composite pour la prevention des adherences post-chirurgicales et son procede d'obtention
FR2766716B1 (fr) * 1997-08-01 2000-02-18 Cogent Sarl Prothese composite pour la prevention des adherences post-chirurgicales et son procede d'obtention
US6486214B1 (en) * 1997-09-10 2002-11-26 Rutgers, The State University Of New Jersey Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby
US6468519B1 (en) 1997-09-10 2002-10-22 Rutgers, The State University Of New Jersey Polyanhydrides with biologically active degradation products
US7122615B1 (en) 1998-09-10 2006-10-17 Rutgers, The State University Of New Jersey Polyanhydrides with therapeutically useful degradation products
US8858981B2 (en) * 1997-10-10 2014-10-14 Ed. Geistlich Soehne Fuer Chemistrie Industrie Bone healing material comprising matrix carrying bone-forming cells
US20030180263A1 (en) 2002-02-21 2003-09-25 Peter Geistlich Resorbable extracellular matrix for reconstruction of bone
US9034315B2 (en) 1997-10-10 2015-05-19 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Cell-charged multi-layer collagen membrane
US20050186283A1 (en) * 1997-10-10 2005-08-25 Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie Collagen carrier of therapeutic genetic material, and method
US6244868B1 (en) * 1997-12-10 2001-06-12 Douglas Alan Schappert Integrated guided-tissue-regeneration barrier for root-form dental implants
US20050208114A1 (en) * 1998-03-24 2005-09-22 Petito George D Composition and method for healing tissues
US7691829B2 (en) * 1998-03-24 2010-04-06 Petito George D Composition and method for healing tissues
CN1323228A (zh) * 1998-08-14 2001-11-21 维里根国际移植服务(Vtsi)股份公司 用于软骨细胞移植的方法、器械和材料
EP1022031B1 (de) * 1999-01-21 2005-03-23 Nipro Corporation Nähbare Membran zur Adhäsionsverhinderung
US20020102709A1 (en) * 1999-02-19 2002-08-01 Tetsuya Ishikawa Collagen-binding physiologically active polypeptide
US7345039B2 (en) 1999-06-04 2008-03-18 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer
US8030301B2 (en) 1999-06-04 2011-10-04 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of cancers with methylol-containing compounds and at least one electrolyte
US7892530B2 (en) 1999-06-04 2011-02-22 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of tumor metastases and cancer
US20020116063A1 (en) * 1999-08-02 2002-08-22 Bruno Giannetti Kit for chondrocyte cell transplantation
US6312474B1 (en) 1999-09-15 2001-11-06 Bio-Vascular, Inc. Resorbable implant materials
US6221109B1 (en) * 1999-09-15 2001-04-24 Ed. Geistlich Söhne AG fur Chemische Industrie Method of protecting spinal area
EP1797884B1 (de) * 1999-12-06 2013-09-11 Geistlich Pharma AG Taurolidin oder Taurultam zur Verwendung bei der Behandlung von Tumoren der Prostata, des Kolons, der Lungen und von wiederkehrendem Glioblastoma multiforme.
US20040038948A1 (en) 1999-12-07 2004-02-26 Uhrich Kathryn E. Therapeutic compositions and methods
ATE444086T1 (de) 1999-12-07 2009-10-15 Univ Rutgers Therapeutische zusammensetzungen und verfahren zur behandlung von periodontitis mit entzündunshemmenden mitteln
US6685928B2 (en) 1999-12-07 2004-02-03 Rutgers, The State University Of New Jersey Therapeutic compositions and methods
US6623963B1 (en) 1999-12-20 2003-09-23 Verigen Ag Cellular matrix
US6641571B2 (en) 2000-01-05 2003-11-04 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Reduction of postoperative complications of cardiopulmonary bypass (CPB) surgery
US6682760B2 (en) 2000-04-18 2004-01-27 Colbar R&D Ltd. Cross-linked collagen matrices and methods for their preparation
KR100520944B1 (ko) * 2000-05-26 2005-10-17 꼴레띠까 인공조직 및 생체재료 제조용 콜라겐 지지체
CZ301649B6 (cs) * 2000-06-28 2010-05-12 Ed. Geistlich Soehne Ag Fur Chemische Industrie Incorporated Under The Laws Of Switzerland Trubice pro regeneraci nervu a zpusob jejich výroby
DK177997B1 (da) 2000-07-19 2015-02-23 Ed Geistlich Söhne Ag Für Chemische Ind Knoglemateriale og collagenkombination til opheling af beskadigede led
IT1318663B1 (it) * 2000-08-02 2003-08-27 Mediolanum Farmaceutici Srl Membrane di collagene a due facce di cui una organizzata a livellomacromolecolare.
CA2365376C (en) 2000-12-21 2006-03-28 Ethicon, Inc. Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
ATE359094T1 (de) * 2001-02-14 2007-05-15 Genzyme Corp Biokompatibles vlies für hämostase und gewebeaufbau
AU784394B2 (en) 2001-04-27 2006-03-23 Geistlich Pharma Ag Method and membrane for mucosa regeneration
US6444222B1 (en) * 2001-05-08 2002-09-03 Verigen Transplantation Services International Ag Reinforced matrices
AU2002300450B2 (en) * 2001-08-10 2007-04-05 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Collagen Carrier of Therapeutic Genetic Material, and Method
JP2003160506A (ja) * 2001-08-10 2003-06-03 Ed Geistlich Soehne Ag Fuer Chemische Industrie 治療用遺伝物質のコラーゲン担体およびその方法
CA2412012C (en) 2001-11-20 2011-08-02 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Resorbable extracellular matrix containing collagen i and collagen ii for reconstruction of cartilage
US20030187515A1 (en) 2002-03-26 2003-10-02 Hariri Robert J. Collagen biofabric and methods of preparing and using the collagen biofabric
US7166133B2 (en) * 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
US20040096476A1 (en) * 2002-07-17 2004-05-20 Uhrich Kathryn E. Therapeutic devices for patterned cell growth
US20040136968A1 (en) * 2002-09-27 2004-07-15 Verigen Ag Autologous cells on a support matrix for tissue repair
US20040078090A1 (en) 2002-10-18 2004-04-22 Francois Binette Biocompatible scaffolds with tissue fragments
US7144588B2 (en) 2003-01-17 2006-12-05 Synovis Life Technologies, Inc. Method of preventing surgical adhesions
KR101141985B1 (ko) 2003-02-06 2012-05-17 고지 니시다 각막 상피 형성용 세포 시트, 그들의 제조 방법 및 그들의이용 방법
US7368124B2 (en) * 2003-03-07 2008-05-06 Depuy Mitek, Inc. Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof
US8197837B2 (en) * 2003-03-07 2012-06-12 Depuy Mitek, Inc. Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof
US8226715B2 (en) 2003-06-30 2012-07-24 Depuy Mitek, Inc. Scaffold for connective tissue repair
US10583220B2 (en) 2003-08-11 2020-03-10 DePuy Synthes Products, Inc. Method and apparatus for resurfacing an articular surface
US7296998B2 (en) * 2003-09-22 2007-11-20 Bartee Chaddick M Hydrophilic high density PTFE medical barrier
DE10349722A1 (de) 2003-10-23 2005-06-16 Beschorner, Katharina, Dr. Zusammensetzung zur Arthrose-/Arthritisbehandlung, insbesondere von Gelenken
US11395865B2 (en) 2004-02-09 2022-07-26 DePuy Synthes Products, Inc. Scaffolds with viable tissue
CA2570623C (en) * 2004-04-30 2013-06-18 Sunstar Suisse Sa Biocompatible membrane formed by a lamination-forming process or a powder electrostatic coating process
CN100372576C (zh) * 2004-12-29 2008-03-05 东华大学 可促进神经再生的复合胶原神经导管及其中空湿法纺丝成形方法
WO2007005807A2 (en) * 2005-06-30 2007-01-11 Anthrogenesis Corporation Repair of tympanic membrane using placenta derived collagen biofabric
CN101252948A (zh) * 2005-09-02 2008-08-27 埃德盖斯特利希索恩化学工业股份公司 修复半月板撕裂的方法
EP2345434A3 (de) 2005-10-24 2012-04-11 Ed. Geistlich Söhne Ag Für Chemische Industrie Verfahren und Vorrichtung für eine Synoviazellen-geladene Kollagenmembran oder ein Gel
ES2308709T3 (es) * 2006-04-05 2008-12-01 Opocrin S.P.A. Membranas de colageno multimicrolaminares.
US20080026032A1 (en) * 2006-07-27 2008-01-31 Zubery Yuval Composite implants for promoting bone regeneration and augmentation and methods for their preparation and use
WO2008021391A1 (en) * 2006-08-15 2008-02-21 Anthrogenesis Corporation Umbilical cord biomaterial for medical use
WO2008029264A2 (en) * 2006-09-07 2008-03-13 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method of treating bone cancer
EP2102144A4 (de) 2006-09-13 2011-03-23 Univ Rutgers Wirkstoffe und ihre oligomere und polymere
WO2008042441A1 (en) * 2006-10-03 2008-04-10 Anthrogenesis Corporation Use of umbilical cord biomaterial for ocular surgery
WO2008060377A2 (en) 2006-10-04 2008-05-22 Anthrogenesis Corporation Placental or umbilical cord tissue compositions
CN101622007A (zh) 2006-10-06 2010-01-06 人类起源公司 天然(端肽)胎盘胶原组合物
PT2097116E (pt) 2006-12-22 2012-12-06 Medidom Lab Sistema in situ para reparação de tecido intra-articular condral e ósseo
US9056151B2 (en) 2007-02-12 2015-06-16 Warsaw Orthopedic, Inc. Methods for collagen processing and products using processed collagen
US9308068B2 (en) 2007-12-03 2016-04-12 Sofradim Production Implant for parastomal hernia
US9095569B2 (en) 2008-04-18 2015-08-04 Collplant Ltd. Methods of generating and using procollagen
US9480549B2 (en) 2008-04-25 2016-11-01 Allosource Multi-layer tissue patches
US9358320B2 (en) 2008-04-25 2016-06-07 Allosource Multi-layer tissue patches
US9242026B2 (en) 2008-06-27 2016-01-26 Sofradim Production Biosynthetic implant for soft tissue repair
WO2010083487A1 (en) 2009-01-16 2010-07-22 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method and membrane for skin regeneration
FR2949688B1 (fr) 2009-09-04 2012-08-24 Sofradim Production Tissu avec picots revetu d'une couche microporeuse bioresorbable
US20140286911A1 (en) 2013-03-15 2014-09-25 Allosource Cell repopulated collagen matrix for soft tissue repair and regeneration
EP3636293A1 (de) 2010-03-23 2020-04-15 Edwards Lifesciences Corporation Verfahren zur bearbeitung eines scheibenförmigen bioprothese-gewebes
US8790699B2 (en) 2010-04-23 2014-07-29 Warsaw Orthpedic, Inc. Foam-formed collagen strand
US8460691B2 (en) 2010-04-23 2013-06-11 Warsaw Orthopedic, Inc. Fenestrated wound repair scaffold
US8951598B2 (en) 2010-05-07 2015-02-10 Empire Technology Development Llc Nanoscale collagen particles and membranes
US8741317B2 (en) 2010-08-19 2014-06-03 Rutgers, The State University Of New Jersey Slow-degrading polymers comprising salicylic acid for undelayed and sustained drug delivery
US20120221118A1 (en) 2011-02-25 2012-08-30 Obi Biologics, Inc. Materials for soft and hard tissue repair
FR2972626B1 (fr) 2011-03-16 2014-04-11 Sofradim Production Prothese comprenant un tricot tridimensionnel et ajoure
CN102225219B (zh) * 2011-06-01 2014-01-29 陕西博鸿生物科技有限公司 一种骨组织再生引导膜及其制备方法
FR2977790B1 (fr) 2011-07-13 2013-07-19 Sofradim Production Prothese pour hernie ombilicale
FR2977789B1 (fr) 2011-07-13 2013-07-19 Sofradim Production Prothese pour hernie ombilicale
CA2849052C (en) 2011-09-30 2019-11-05 Sofradim Production Reversible stiffening of light weight mesh
US9162011B2 (en) 2011-12-19 2015-10-20 Allosource Flowable matrix compositions and methods
FR2985170B1 (fr) 2011-12-29 2014-01-24 Sofradim Production Prothese pour hernie inguinale
FR2985271B1 (fr) 2011-12-29 2014-01-24 Sofradim Production Tricot a picots
US10071184B2 (en) * 2012-02-29 2018-09-11 Collagen Matrix, Inc. Collagen-coated tissue-based membranes
EP2674166A1 (de) * 2012-06-15 2013-12-18 Universitätsmedizin der Johannes Gutenberg-Universität Mainz Verwendung von Erythropoietin (EPO) zur lokalen Behandlung von Kiefer-Osteonekrose im Zusammenhang mit der Krebsbehandlung
KR101455837B1 (ko) * 2012-07-09 2014-11-03 주식회사 오스코텍 조직 재생 유도용 흡수성 차폐막의 제조방법
US9644177B2 (en) * 2012-07-12 2017-05-09 Board Of Regents, The University Of Texas System Extracellular matrix films and methods of making and using same
FR2994185B1 (fr) 2012-08-02 2015-07-31 Sofradim Production Procede de preparation d’une couche poreuse a base de chitosane
US9144579B2 (en) 2012-08-17 2015-09-29 Rutgers, The State University Of New Jersey Polyesters and methods of use thereof
FR2995778B1 (fr) 2012-09-25 2015-06-26 Sofradim Production Prothese de renfort de la paroi abdominale et procede de fabrication
FR2995779B1 (fr) 2012-09-25 2015-09-25 Sofradim Production Prothese comprenant un treillis et un moyen de consolidation
FR2995788B1 (fr) 2012-09-25 2014-09-26 Sofradim Production Patch hemostatique et procede de preparation
CA2880380C (en) 2012-09-28 2020-09-15 Sofradim Production Packaging for a hernia repair device
US20140120057A1 (en) 2012-10-25 2014-05-01 Rutgers, The State University Of New Jersey Polymers and methods thereof for wound healing
KR101434041B1 (ko) 2012-11-08 2014-08-29 주식회사 제네웰 생체조직 유래 소재로부터 제조된 재생 유도용 멤브레인 제조방법
CN103961752B (zh) * 2013-02-02 2016-01-20 深圳兰度生物材料有限公司 组织再生引导膜及其制备方法
AU2014248873B2 (en) 2013-03-13 2017-03-23 Allosource Fascia fibrous compositions and methods for their use and manufacture
US9387250B2 (en) 2013-03-15 2016-07-12 Rutgers, The State University Of New Jersey Therapeutic compositions for bone repair
WO2014194055A1 (en) 2013-05-29 2014-12-04 Rutgers, The State University Of New Jersey Antioxidant-based poly(anhydride-esters)
FR3006578B1 (fr) 2013-06-07 2015-05-29 Sofradim Production Prothese a base d’un textile pour voie laparoscopique
FR3006581B1 (fr) 2013-06-07 2016-07-22 Sofradim Production Prothese a base d’un textile pour voie laparoscopique
EP2826495A1 (de) 2013-07-19 2015-01-21 Geistlich Pharma AG Biomimetisches Kollagen-Hydroxyapatit-Verbundmaterial
EP2842515A1 (de) 2013-08-29 2015-03-04 nolax AG Membran, Operations-Set mit Membran und Verfahren zum Applizieren einer Membran
KR101832203B1 (ko) 2013-12-06 2018-02-27 알로소스 조직의 시트를 건조하는 방법
US10023521B2 (en) 2014-06-13 2018-07-17 Rutgers, The State University Of New Jersey Process and intermediates for preparing poly(anhydride-esters)
US20170189159A1 (en) 2014-06-24 2017-07-06 Osteogenics Biomedical, Inc. Perforated membrane for guided bone and tissue regeneration
EP3000489B1 (de) 2014-09-24 2017-04-05 Sofradim Production Verfahren zur Herstellung einer Antihaft-Sperrschicht
EP3000433B1 (de) 2014-09-29 2022-09-21 Sofradim Production Vorrichtung zur Einführung einer Prothese zur Hernie-Behandlung in einen Einschnitt und flexible textile Prothese
EP3000432B1 (de) 2014-09-29 2022-05-04 Sofradim Production Textilbasierte Prothese für die Behandlung von Leistenbruch
EP3029189B1 (de) 2014-12-05 2021-08-11 Sofradim Production Prothetisches poröses Netz, sein Herstellungsverfahren und Hernienprothese
EP3034103A1 (de) 2014-12-15 2016-06-22 Geistlich Pharma AG Kollagenschwamm
EP3059255B1 (de) 2015-02-17 2020-05-13 Sofradim Production Verfahren zur Herstellung einer Matrix auf Chitosanbasis mit faseroptischem Verstärkungselement
JP6930918B6 (ja) 2015-04-10 2021-12-15 ラトガーズ， ザ ステイト ユニバーシティ オブ ニュー ジャージー コウジ酸ポリマー
EP3085337B1 (de) 2015-04-24 2022-09-14 Sofradim Production Prothese zur unterstützung einer bruststruktur
WO2016186594A1 (en) * 2015-05-20 2016-11-24 SUNAL, Elif A barrier membrane used in periodontitis treatment and a production method thereof
EP3106185B1 (de) 2015-06-19 2018-04-25 Sofradim Production Synthetische prothese mit einem gewirk und einem nichtporösen film und verfahren zur formung davon
EP3175869A1 (de) 2015-12-04 2017-06-07 Geistlich Pharma AG Vernetzte resorbierbare formstabile membran
IL243401A (en) 2015-12-29 2017-12-31 Zion Karmon Ben Instruments and methods for lifting Schneider membrane
EP3195830B1 (de) 2016-01-25 2020-11-18 Sofradim Production Prothese zur hernienreparatur
IL248472A0 (en) 2016-10-13 2017-01-31 Zion Karmon Ben Devices for tissue growth
EP3312325B1 (de) 2016-10-21 2021-09-22 Sofradim Production Verfahren zur herstellung eines netzes mit einem daran befestigten nahtmaterial mit widerhaken und dadurch erhaltenes netz
US10772986B2 (en) 2017-01-26 2020-09-15 Allosource Fascia fibrous compositions and methods for their use and manufacture
EP3398554B1 (de) 2017-05-02 2025-06-25 Sofradim Production Prothese zur leistenbruch reparatur
US12076422B2 (en) 2017-05-10 2024-09-03 Marquette University Medical and dental integrated multiphasic biomaterials for single or multi-tissue reconstruction/regeneration
EP3409303A1 (de) * 2017-06-02 2018-12-05 Geistlich Pharma AG Verwendung einer resorbierbaren vernetzten, formstabilen zusammensetzung zur herstellung einer membran
KR102330140B1 (ko) 2017-12-14 2021-11-23 가이스틀리히 파마 아게 건조 임플란트 조성물 및 주사가능한 수성 임플란트 제형
EP3653171B1 (de) 2018-11-16 2024-08-21 Sofradim Production Implantate zur weichgewebereparatur
US10869949B2 (en) 2019-04-11 2020-12-22 Geistlich Pharma Ag Method for treating subjects suffering from chronic ulcers
WO2020249714A1 (en) * 2019-06-14 2020-12-17 Geistlich Pharma Ag Collagen matrix or granulate blend of bone substitute material
WO2020249711A1 (en) 2019-06-14 2020-12-17 Geistlich Pharma Ag Injectable aqueous implant formulation containing ascorbic acid
TWI869413B (zh) 2019-06-14 2025-01-11 瑞士商蓋茲特利製藥公司 骨替代材料之膠原蛋白基質或顆粒摻合物及其用途
CZ308980B6 (cs) 2020-01-24 2021-11-03 Contipro A.S. Dentální přípravek z vláken na bázi kyseliny hyaluronové s regulovatelnou biodegradabilitou
US12064330B2 (en) 2020-04-28 2024-08-20 Covidien Lp Implantable prothesis for minimally invasive hernia repair
EP4209232A1 (de) 2022-01-06 2023-07-12 Geistlich Pharma AG Kollagenvorrichtung zur meniskusregeneration

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2517452C3 (de) * 1975-04-19 1978-11-02 Fa. Carl Freudenberg, 6940 Weinheim Kollagenfolie für kosmetische Anwendung
US4060081A (en) * 1975-07-15 1977-11-29 Massachusetts Institute Of Technology Multilayer membrane useful as synthetic skin
US4185011A (en) * 1978-10-16 1980-01-22 Firma Carl Freudenberg Process for the production of collagen fibers
US4292972A (en) * 1980-07-09 1981-10-06 E. R. Squibb & Sons, Inc. Lyophilized hydrocolloio foam
DE3203957A1 (de) * 1982-02-05 1983-08-18 Chemokol Gesellschaft zur Entwicklung von Kollagenprodukten, 5190 Stolberg Verfahren zur herstellung von feinporigen kollagenschwaemmen
US4600533A (en) * 1984-12-24 1986-07-15 Collagen Corporation Collagen membranes for medical use
US4674488A (en) * 1985-03-04 1987-06-23 American Hospital Supply Corporation Method of treating bone fractures to reduce formation of fibrous adhesions
ATE86115T1 (de) 1987-04-28 1993-03-15 Univ California Vorrichtung und verfahren zur herstellung eines komposithautersatzes.
ATE109491T1 (de) 1988-03-11 1994-08-15 Chemokol G B R Ing Buero Fuer Verfahren zur herstellung von kollagenmembranen für hämostase, wundbehandlung und implantate.
US5573771A (en) * 1988-08-19 1996-11-12 Osteomedical Limited Medicinal bone mineral products
WO1990013302A1 (en) * 1989-04-28 1990-11-15 Brigham And Women's Hospital Novel materials and methods for guided tissue regeneration
FR2679778B1 (fr) * 1991-08-02 1995-07-07 Coletica Utilisation de collagene reticule par un agent de reticulation pour la fabrication d'une membrane suturable, biocompatible, a resorption lente, ainsi qu'une telle membrane.
FI942425L (fi) * 1991-11-26 1994-05-25 Res Dev Foundation Sikiökalvoista tehtyjä putkia hermo- ja verisuonisiirteitä varten

Also Published As

Publication number Publication date
US5837278A (en) 1998-11-17
DE69534713D1 (de) 2006-02-02
CA2180659C (en) 2006-11-21
DE69534713T2 (de) 2006-07-06
EP0738161B1 (de) 2005-12-28
CA2180659A1 (en) 1995-07-13
WO1995018638A1 (en) 1995-07-13
EP0738161A1 (de) 1996-10-23
EP1676592B1 (de) 2013-01-23
EP1676592A1 (de) 2006-07-05
ES2400947T3 (es) 2013-04-15
ES2255707T3 (es) 2006-07-01
JPH09507144A (ja) 1997-07-22
JP3577083B2 (ja) 2004-10-13
GB9400163D0 (en) 1994-03-02

Similar Documents

Publication Publication Date Title
ATE314102T1 (de) Verwendung einer kollagenmembrane zur herstellung eines implantates für gesteuerte geweberegeneration
Winter Transcutaneous implants: Reactions of the skin‐implant interface
Burke et al. Successful use of a physiologically acceptable artificial skin in the treatment of extensive burn injury
US5334527A (en) Epidermal graft system
Pandya et al. The use of cultured autologous keratinocytes with Integra in the resurfacing of acute burns
US4418691A (en) Method of promoting the regeneration of tissue at a wound
Hansbrough et al. Burn wound closure with cultured autologous keratinocytes and fibroblasts attached to a collagen-glycosaminoglycan substrate
Chick Brief history and biology of skin grafting
CA2213533A1 (en) Resorbable extracellular matrix for reconstruction of cartilage tissue
ATE372747T1 (de) Verfahren zur herstellung einer bio-umbaubare transplantatprothese aus kollagen
DE69532976D1 (de) Herstellungsverfahren von gewebe zur implantation
ATE308926T1 (de) Nicht antigenische und durch peressigsäure vernetzte transplantate mit innerer kollagenschicht
Mol et al. Grafting of venous leg ulcers: an intraindividual comparison between cultured skin equivalents and full-thickness skin punch grafts
AU2002364664B2 (en) Device for active phase cell or tissue sampling and uses thereof
Kangesu et al. A porcine model using skin graft chambers for studies on cultured keratinocytes
AR004492A1 (es) Cabello artificial para implante y procedimiento para producir el mismo
Yannas Applications of ECM analogs in surgery
Burke Observations on the development and clinical use of artificial skin—An attempt to employ regeneration rather than scar formation in wound healing—
De Luca et al. Permanent coverage of full skin thickness burns with autologous cultured epidermis and reepithelialization of partial skin thickness lesions induced by allogeneic cultured epidermis: a multicentre study in the treatment of children
Gallego et al. Use of cultured human epithelium for coverage: a defect of radial forearm free flap donor site
CA2073453A1 (en) Methods of enhancing wound healing and tissue repair
ATE190507T1 (de) Biodegradierbare führungskanäle zur verwendung als chirurgische hilfsmittel in gewebewiederherstellung
Silver Wound dressings and skin replacement
Atnip et al. Skin coverage
Yurugi et al. Usefulness and limitations of artificial dermis implantation for posttraumatic deformity

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0738161

Country of ref document: EP