ATE305793T1 - Bakteriophage mit breitem wirtspektrum - Google Patents

Bakteriophage mit breitem wirtspektrum

Info

Publication number
ATE305793T1
ATE305793T1 AT01955955T AT01955955T ATE305793T1 AT E305793 T1 ATE305793 T1 AT E305793T1 AT 01955955 T AT01955955 T AT 01955955T AT 01955955 T AT01955955 T AT 01955955T AT E305793 T1 ATE305793 T1 AT E305793T1
Authority
AT
Austria
Prior art keywords
bacteriophage
broad host
host spectrum
spectrum
broad
Prior art date
Application number
AT01955955T
Other languages
English (en)
Inventor
Carl R Merril
Sankar Adhya
Deal Scholl
Original Assignee
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv
Application granted granted Critical
Publication of ATE305793T1 publication Critical patent/ATE305793T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/14011Details ssDNA Bacteriophages
    • C12N2795/14211Microviridae
    • C12N2795/14232Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/948Microorganisms using viruses or cell lines

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Toys (AREA)
  • Feedback Control In General (AREA)
AT01955955T 2000-07-25 2001-07-25 Bakteriophage mit breitem wirtspektrum ATE305793T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22098700P 2000-07-25 2000-07-25
PCT/US2001/023390 WO2002007742A2 (en) 2000-07-25 2001-07-25 Bacteriophage having multiple host range

Publications (1)

Publication Number Publication Date
ATE305793T1 true ATE305793T1 (de) 2005-10-15

Family

ID=22825862

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01955955T ATE305793T1 (de) 2000-07-25 2001-07-25 Bakteriophage mit breitem wirtspektrum

Country Status (8)

Country Link
US (1) US7163818B2 (de)
EP (1) EP1305038B1 (de)
AT (1) ATE305793T1 (de)
AU (1) AU2001278003A1 (de)
CA (1) CA2417188A1 (de)
DE (1) DE60113851T2 (de)
ES (1) ES2252263T3 (de)
WO (1) WO2002007742A2 (de)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0895534A1 (de) * 1996-04-15 1999-02-10 Nymox Corporation Bakteriophagen enthaltende zusammensetzungen und methoden zur verwendung von bakteriophagen zur behandlung von infektionen
DE60231168D1 (de) 2001-06-15 2009-04-02 Prysmian Cables & Systems Ltd Verbinden optischer Fasern
CN1260353C (zh) * 2001-07-18 2006-06-21 波兰科学院免疫和实验治疗研究所 用于治疗细菌感染的多价噬菌体制备方法
GB0209680D0 (en) * 2002-04-27 2002-06-05 Univ Strathclyde Immobilisation and stabilisation of bacteriophage
US7588929B2 (en) 2002-12-09 2009-09-15 Phage Biopharm Llc Production of bacteriophage compositions for use in phage therapy
GB0300597D0 (en) 2003-01-10 2003-02-12 Microbiological Res Authority Phage biofilms
US7951579B2 (en) * 2003-04-07 2011-05-31 Board of Trutees of the University of Arkansas Method for bacteriophage delivery and amplification
AU2004258731B2 (en) 2003-07-23 2010-02-25 Biocontrol Limited Bacteriophage-containing therapeutic agents
GB0320838D0 (en) 2003-09-05 2003-10-08 Univ Nottingham Disinfection of foodstuffs
CA2593992A1 (en) * 2004-12-06 2006-06-15 Rodney M. Donlan Inhibition of biofilm formation using bacteriophage
WO2006066224A2 (en) * 2004-12-14 2006-06-22 Yale University Virulence targeted antibiotics
CA2775655C (en) * 2005-01-20 2014-03-25 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Multiplexed analysis for determining a serodiagnosis of viral infection
WO2006095345A2 (en) * 2005-03-08 2006-09-14 Ramot At Tel-Aviv University Ltd. Targeted drug-carrying bacteriophages
WO2007007055A1 (en) 2005-07-12 2007-01-18 The University Of Leeds Bacteriophage and their uses
US20090053179A1 (en) * 2005-10-05 2009-02-26 Internalle, Inc. Method for using liberated dormant bacteriophage and environmental stress to reduce infectious bacteria
US8178087B2 (en) 2006-04-04 2012-05-15 Centre National de la Recherche Scientifique —CNRS Process of production of bacteriophage compositions and methods in phage therapy field
KR100781669B1 (ko) * 2006-06-20 2007-12-03 주식회사 인트론바이오테크놀로지 황색포도상구균 특이적 사멸능을 갖는 박테리오파지
KR100759988B1 (ko) * 2006-08-04 2007-09-19 주식회사 인트론바이오테크놀로지 황색포도상구균에 특이적인 항균 단백질
FR2910493B1 (fr) * 2006-12-20 2012-12-14 Bio Modeling Systems Ou Bmsystems Procede de diversification aleatoire d'une sequence genetique permettant de preserver l'identite de certains segments internes de ladite sequence genetique
FR2910492B1 (fr) * 2006-12-20 2013-02-15 Bio Modeling Systems Ou Bmsystems Procede de preparation de bacteriophages modifies par insertion de sequences aleatoires dans les proteines de ciblage desdits bacteriophages
GB0704553D0 (en) 2007-03-09 2007-04-18 Harper David R Beneficial effects of bacteriophage treatments
EP2145015A4 (de) * 2007-03-30 2012-02-29 Ca Nat Research Council Phagenrezeptorbindende proteine für antibakterielle therapie und andere neuartige verwendungen
KR100910961B1 (ko) * 2007-09-13 2009-08-05 주식회사 인트론바이오테크놀로지 황색포도상구균의 균막 처치에 효과적인 박테리오파지 또는그것 유래의 용균단백질
US20100092431A1 (en) * 2008-05-15 2010-04-15 Auburn University Edwardsiella Ictaluri Bacteriophage and Uses Thereof
US8377866B2 (en) * 2009-02-12 2013-02-19 Intron Biotechnology, Inc. Antimicrobial protein derived from Podoviridae bacteriophage specific to Staphylococcus aureus
TWI458734B (zh) * 2011-04-20 2014-11-01 Univ Nat Taiwan 對克雷伯氏肺炎桿菌(klebsiella pneumoniae)莢膜型菌株具專一性的新穎多肽及噬菌體及其應用
WO2013010660A1 (en) * 2011-07-15 2013-01-24 Medizinische Hochschule Hannover (Mhh) Enzymes having alpha2,9 endosialidase activity
RU2518303C2 (ru) * 2012-06-29 2014-06-10 Федеральное бюджетное учреждение науки "Московский научно-исследовательский институт эпидемиологии и микробиологии имени Г.Н. Габричевского" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФБУН МНИИЭМ им. Г.Н. Габричевского Роспотребнадзора) КОМПОЗИЦИЯ АНТИБАКТЕРИАЛЬНАЯ, ШТАММ БАКТЕРИОФАГА Escherichia coli, ИСПОЛЬЗУЕМЫЙ ДЛЯ ПОЛУЧЕНИЯ ТАКОЙ КОМПОЗИЦИИ.
WO2015035168A1 (en) * 2013-09-05 2015-03-12 Massachusetts Institute Of Technolgy Tuning bacteriophage host range
EP2893933A1 (de) * 2014-01-10 2015-07-15 Pherecydes Pharma Phagentherapie von E.coli-Infektionen
GB201417811D0 (en) * 2014-10-08 2014-11-19 Phico Therapeutics Ltd Modifying bacteriophage
GB201417808D0 (en) * 2014-10-08 2014-11-19 Phico Therapeutics Ltd Modified bacteriophage
GB201417810D0 (en) 2014-10-08 2014-11-19 Phico Therapeutics Ltd Modifying bacteriophage
GB201417805D0 (en) * 2014-10-08 2014-11-19 Phico Therapeutics Ltd Modifield bacteriophage
EP3018201A1 (de) 2014-11-07 2016-05-11 Pherecydes Pharma Phagentherapie
CN107278227B (zh) 2014-12-16 2021-05-28 C3J治疗公司 用于体外病毒基因组工程的组合物和方法
US10781441B2 (en) 2016-04-08 2020-09-22 Phico Therapeutics Ltd Modifying bacteriophage
JP7051809B2 (ja) 2016-04-08 2022-04-11 フィコ セラピューティクス リミテッド 改変バクテリオファージ
WO2018081502A1 (en) * 2016-10-28 2018-05-03 Massachusetts Intitute Of Technology Synthetic bacteriophages and bacteriophage compositions
KR101822812B1 (ko) * 2017-02-22 2018-01-29 주식회사 인트론바이오테크놀로지 신규한 엔테로코쿠스 패슘 박테리오파지 Ent-FAP-4 및 이의 엔테로코쿠스 패슘 증식 억제 용도
US10174295B1 (en) * 2017-08-01 2019-01-08 The Charles Stark Draper Laboratory, Inc. Composition of matter: engineering of Escherichia coli phage K1E
GB201712733D0 (en) 2017-08-08 2017-09-20 Snipr Tech Ltd Methods & cells
WO2019140534A1 (en) * 2018-01-19 2019-07-25 Cytophage Technologies Inc. Genetically engineered bacteriophage
GB201901099D0 (en) 2019-01-27 2019-03-13 Snipr Biome Aps Methods, uses and compositions
AU2020312725A1 (en) * 2019-07-18 2022-03-03 Technische Universität München Host-independent expression of bacteriophages
CN112695017B (zh) * 2019-10-23 2022-04-15 吉林大学 噬菌体vB_Yen_X1及在防治鼠疫杆菌感染中应用
US11584781B2 (en) 2019-12-30 2023-02-21 Eligo Bioscience Chimeric receptor binding proteins resistant to proteolytic degradation
CN111876400B (zh) * 2020-08-06 2022-05-24 昆明理工大学 一种常温裂解酶Sly和编码此酶的多核苷酸
CN112143747B (zh) * 2020-09-09 2022-09-13 昆明理工大学 一种噬菌体裂解酶及其基因、基因重组表达载体与应用
CN113215114A (zh) * 2021-06-09 2021-08-06 西南石油大学 一种ndm-1大肠杆菌噬菌体及其分离方法和应用
GB202209518D0 (en) 2022-06-29 2022-08-10 Snipr Biome Aps Treating & preventing E coli infections
WO2024003301A1 (en) 2022-06-29 2024-01-04 Snipr Biome Aps Targeting e coli cells

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405720A (en) 1981-03-04 1983-09-20 The United States Of America As Represented By The Department Of Health And Human Services Silver stains for protein in gels
US4508820A (en) 1982-08-13 1985-04-02 The United States Of America As Represented By The Department Of Health And Human Services Method for simultaneously monitoring turnover rate in multiple proteins
US4555490A (en) 1984-06-08 1985-11-26 The United States Of America As Represented By The Department Of Health And Human Services Rapid visualization system for gel electrophoresis
US4703016A (en) 1986-05-05 1987-10-27 The United States Of America As Represented By The Department Of Health And Human Services Silver stain for rapid, quantitative detection of polypeptides and nucleic acids
US4940659A (en) 1987-02-20 1990-07-10 Monoclonetics International, Inc. Screening extra-cellular body fluids for superoxide dismutase (SOD-1) for determining fetal trisomy 21 down syndrome
US4892814A (en) 1987-06-22 1990-01-09 The United States Of America As Represented By The Department Of Health And Human Services Method for distinguishing Creutzfeldt-Jakob disease from other dementias
US5817797A (en) 1988-06-01 1998-10-06 The United States Of America As Represented By The Department Of Health And Human Services Sequencing DNA; a modification of the polymerase chain reaction
US5292665A (en) 1989-03-15 1994-03-08 The United States Of America As Represented By The Department Of Health And Human Services Catalyst for preparing polyacrylamide gel which improves the detection of biomaterials by silver staining
AU667462B2 (en) 1990-11-30 1996-03-28 Monoclonetics International Incorporated Methods for the diagnosis of chronic lower back and cervical pain
US5844097A (en) 1990-11-30 1998-12-01 Monoclonetics International, Inc. Methods for the diagnosis of peripheral nerve damage
US5468610A (en) 1991-05-29 1995-11-21 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Three highly informative microsatellite repeat polymorphic DNA markers
US5861504A (en) 1991-05-29 1999-01-19 The United States Of America As Represented By The Department Of Health And Human Services Eleven highly informative microsatelite repeat polymorphic DNA markers
US5378602A (en) 1991-05-29 1995-01-03 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Highly informative microsatellite repeat polymorphic DNA markers twenty-[seven]six
US5429947A (en) 1992-06-17 1995-07-04 Merril; Carl R. Diagnosing Alzheimer's disease and schizophrenia
US20010043924A1 (en) 1994-04-05 2001-11-22 Exponential Biotherapies, Inc. Antibacterial therapy with bacteriophage physico-chemically altered to delay inactivation by the host defense system
US5811093A (en) 1994-04-05 1998-09-22 Exponential Biotherapies, Inc. Bacteriophage genotypically modified to delay inactivations by the host defense system
JPH09511397A (ja) 1994-04-05 1997-11-18 エクスポネンシャル バイオセラピーズ,インコーポレイテッド 遺伝子型改変バクテリオファージによる抗菌治療
US5736388A (en) * 1994-12-30 1998-04-07 Chada; Sunil Bacteriophage-mediated gene transfer systems capable of transfecting eukaryotic cells
SE506771C2 (sv) * 1996-02-06 1998-02-09 Gotpat 105 Ab Fusionsprotein, bakteriofag uttryckande proteinet, dessas användning samt hybridoma celler och monoklonaler producerade av cellerna
AU3737297A (en) * 1996-08-05 1998-02-25 Brigham And Women's Hospital Bacteriophage-mediated gene therapy
US20020177614A1 (en) 2001-03-23 2002-11-28 Merril Carl R. Methods for treating nuerodegenerative diseases including alzheimer's
US7521479B2 (en) 2001-04-16 2009-04-21 Panacea Pharmaceuticals, Inc. Methods of treating prion disease in mammals
WO2004041156A2 (en) 2002-01-23 2004-05-21 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health Andhuman Services Method for determining sensitivity to a bacteriophage
US7399753B2 (en) 2002-02-25 2008-07-15 Virxsys Corporation Trans-splicing mediated photodynamic therapy

Also Published As

Publication number Publication date
US20030216338A1 (en) 2003-11-20
EP1305038B1 (de) 2005-10-05
WO2002007742A2 (en) 2002-01-31
DE60113851T2 (de) 2006-07-20
DE60113851D1 (de) 2006-02-16
EP1305038A2 (de) 2003-05-02
US7163818B2 (en) 2007-01-16
ES2252263T3 (es) 2006-05-16
WO2002007742A3 (en) 2002-08-08
WO2002007742A8 (en) 2003-10-30
WO2002007742A9 (en) 2002-04-18
CA2417188A1 (en) 2002-01-31
AU2001278003A1 (en) 2002-02-05

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