ATE302197T1 - Amidderivate - Google Patents

Amidderivate

Info

Publication number
ATE302197T1
ATE302197T1 AT01981033T AT01981033T ATE302197T1 AT E302197 T1 ATE302197 T1 AT E302197T1 AT 01981033 T AT01981033 T AT 01981033T AT 01981033 T AT01981033 T AT 01981033T AT E302197 T1 ATE302197 T1 AT E302197T1
Authority
AT
Austria
Prior art keywords
accompanied
amide derivative
infection
herpes
hsv
Prior art date
Application number
AT01981033T
Other languages
German (de)
English (en)
Inventor
Toru Kontani
Junji Miyata
Wataru Hamaguchi
Yoji Miyazaki
Hiroshi Suzuki
Eiichi Nakai
Shunji Kageyama
Original Assignee
Yamanouchi Pharma Co Ltd
Rational Drug Design Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharma Co Ltd, Rational Drug Design Lab filed Critical Yamanouchi Pharma Co Ltd
Application granted granted Critical
Publication of ATE302197T1 publication Critical patent/ATE302197T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/70Sulfur atoms
    • C07D277/74Sulfur atoms substituted by carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/40Unsubstituted amino or imino radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/64Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT01981033T 2000-11-10 2001-11-08 Amidderivate ATE302197T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000344354 2000-11-10
PCT/JP2001/009790 WO2002038554A1 (fr) 2000-11-10 2001-11-08 Derives amides

Publications (1)

Publication Number Publication Date
ATE302197T1 true ATE302197T1 (de) 2005-09-15

Family

ID=18818562

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01981033T ATE302197T1 (de) 2000-11-10 2001-11-08 Amidderivate

Country Status (11)

Country Link
US (1) US6949543B2 (fr)
EP (1) EP1340750B8 (fr)
JP (1) JP3913172B2 (fr)
KR (1) KR20030045180A (fr)
CN (1) CN1473157A (fr)
AT (1) ATE302197T1 (fr)
AU (1) AU2002212734A1 (fr)
CA (1) CA2428184C (fr)
DE (1) DE60112790T2 (fr)
ES (1) ES2247177T3 (fr)
WO (1) WO2002038554A1 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003095435A1 (fr) * 2002-05-09 2003-11-20 Yamanouchi Pharmaceutical Co., Ltd. Derives d'amides
TW200505894A (en) * 2003-08-08 2005-02-16 Yamanouchi Pharma Co Ltd Tetrahydro-2H-thiopyran-4-carboxamide derivative
CA2536954C (fr) * 2003-08-29 2012-11-27 Exelixis, Inc. Modulateurs c-kit et leurs procedes d'utilisation
JP2007523087A (ja) * 2004-02-11 2007-08-16 アイアールエム・リミテッド・ライアビリティ・カンパニー Lxrモジュレーターとしての化合物および組成物
WO2005111013A1 (fr) * 2004-05-13 2005-11-24 Boehringer Ingelheim International Gmbh Amides d'acide thiophene-2-carboxylique substitues, leur production et leur utilisation comme medicament
WO2006082821A1 (fr) * 2005-02-02 2006-08-10 Astellas Pharma Inc. Agent preventif ou therapeutique contre une maladie liee au virus de l'herpes
JP4832093B2 (ja) * 2005-02-02 2011-12-07 アステラス製薬株式会社 テトラヒドロ−2h−チオピラン−4−カルボキサミド誘導体の製造方法
ES2342558T3 (es) * 2005-02-02 2010-07-08 Astellas Pharma Inc. Agente para prevencion/tratamiento de una enfermedad causada por un herpesvirus resistente a acyclovir.
CA2596850A1 (fr) * 2005-02-02 2006-08-10 Astellas Pharma Inc. Medicament contre l'herpes genital
JP5011739B2 (ja) * 2005-02-03 2012-08-29 アステラス製薬株式会社 テトラヒドロ−2h−チオピラン−4−カルボキサミド誘導体を含有する医薬組成物
JP5128599B2 (ja) * 2006-08-30 2013-01-23 エフ.ホフマン−ラ ロシュ アーゲー Glyt−1の阻害薬
US9403789B2 (en) 2008-02-21 2016-08-02 Sequoia Pharmaceuticals, Inc. Benzofuran-containing amino acid inhibitors of cytochrome P450
EP2351565A1 (fr) 2008-10-20 2011-08-03 Astellas Pharma Inc. Médicament destiné à la prévention ou au traitement de la douleur associée à un zona
CN103491956A (zh) * 2010-09-13 2014-01-01 麦克罗拜奥提斯公司 病毒进入哺乳动物细胞的抑制剂
EP2647622B1 (fr) * 2010-12-03 2017-04-19 Fujitsu Limited Inhibiteurs de la protéine kinésine du fuseau et leur application
CN103275034B (zh) * 2013-04-16 2015-07-08 南京工业大学 一类小分子cathepsin D抑制剂的制备方法
TW202038947A (zh) 2018-11-28 2020-11-01 德商創新分子有限責任公司 在與溶瘤病毒之組合療法中治療癌症的解旋酶引子酶抑制劑

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4327249B2 (ja) * 1995-12-29 2009-09-09 ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド 抗ヘルペスウイルス性を有するフェニルチアゾール誘導体
AU3289299A (en) * 1998-02-19 1999-09-06 Tularik Inc. Antiviral agents
WO2000029399A1 (fr) * 1998-11-12 2000-05-25 Boehringer Ingelheim (Canada) Ltd. Composes antiherpes

Also Published As

Publication number Publication date
EP1340750A4 (fr) 2004-01-21
JPWO2002038554A1 (ja) 2004-03-18
AU2002212734A1 (en) 2002-05-21
CA2428184C (fr) 2010-03-30
US6949543B2 (en) 2005-09-27
EP1340750B8 (fr) 2005-10-19
ES2247177T3 (es) 2006-03-01
DE60112790T2 (de) 2006-05-18
KR20030045180A (ko) 2003-06-09
JP3913172B2 (ja) 2007-05-09
US20040034232A1 (en) 2004-02-19
EP1340750A1 (fr) 2003-09-03
DE60112790D1 (de) 2005-09-22
WO2002038554A1 (fr) 2002-05-16
EP1340750B1 (fr) 2005-08-17
CA2428184A1 (fr) 2002-05-16
CN1473157A (zh) 2004-02-04

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties