DE60112790D1 - Amidderivate - Google Patents
AmidderivateInfo
- Publication number
- DE60112790D1 DE60112790D1 DE60112790T DE60112790T DE60112790D1 DE 60112790 D1 DE60112790 D1 DE 60112790D1 DE 60112790 T DE60112790 T DE 60112790T DE 60112790 T DE60112790 T DE 60112790T DE 60112790 D1 DE60112790 D1 DE 60112790D1
- Authority
- DE
- Germany
- Prior art keywords
- accompanied
- amide derivative
- infection
- herpes
- hsv
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/70—Sulfur atoms
- C07D277/74—Sulfur atoms substituted by carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000344354 | 2000-11-10 | ||
| JP2000344354 | 2000-11-10 | ||
| PCT/JP2001/009790 WO2002038554A1 (fr) | 2000-11-10 | 2001-11-08 | Derives amides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60112790D1 true DE60112790D1 (de) | 2005-09-22 |
| DE60112790T2 DE60112790T2 (de) | 2006-05-18 |
Family
ID=18818562
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60112790T Expired - Lifetime DE60112790T2 (de) | 2000-11-10 | 2001-11-08 | Amidderivate |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6949543B2 (de) |
| EP (1) | EP1340750B8 (de) |
| JP (1) | JP3913172B2 (de) |
| KR (1) | KR20030045180A (de) |
| CN (1) | CN1473157A (de) |
| AT (1) | ATE302197T1 (de) |
| AU (1) | AU2002212734A1 (de) |
| CA (1) | CA2428184C (de) |
| DE (1) | DE60112790T2 (de) |
| ES (1) | ES2247177T3 (de) |
| WO (1) | WO2002038554A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003235889A1 (en) * | 2002-05-09 | 2003-11-11 | Rational Drug Design Laboratories | Amide derivatives |
| TW200505894A (en) * | 2003-08-08 | 2005-02-16 | Yamanouchi Pharma Co Ltd | Tetrahydro-2H-thiopyran-4-carboxamide derivative |
| WO2005020921A2 (en) | 2003-08-29 | 2005-03-10 | Exelixis, Inc. | C-kit modulators and methods of use |
| JP2007523087A (ja) * | 2004-02-11 | 2007-08-16 | アイアールエム・リミテッド・ライアビリティ・カンパニー | Ｌｘｒモジュレーターとしての化合物および組成物 |
| EP1748997A1 (de) * | 2004-05-13 | 2007-02-07 | Boehringer Ingelheim International Gmbh | Substituierte thiophen-2-carbonsäureamide, deren herstellung und deren verwendung als arzneimittel |
| JP4832093B2 (ja) * | 2005-02-02 | 2011-12-07 | アステラス製薬株式会社 | テトラヒドロ−２ｈ−チオピラン−４−カルボキサミド誘導体の製造方法 |
| DE602006016069D1 (de) * | 2005-02-02 | 2010-09-23 | Astellas Pharma Inc | Therapeutischer wirkstoff zur behandlung von herpes progenitalis nach der entwicklung von läsionen |
| JPWO2006082822A1 (ja) * | 2005-02-02 | 2008-06-26 | アステラス製薬株式会社 | アシクロビル耐性ヘルペスウイルスによる疾患の予防・治療剤 |
| EP1857108B1 (de) * | 2005-02-02 | 2010-12-08 | Astellas Pharma Inc. | Vorbeuge- oder heilmittel für krankheiten in zusammenhang mit dem herpes-virus |
| JP5011739B2 (ja) * | 2005-02-03 | 2012-08-29 | アステラス製薬株式会社 | テトラヒドロ−２ｈ−チオピラン−４−カルボキサミド誘導体を含有する医薬組成物 |
| BRPI0715729A2 (pt) * | 2006-08-30 | 2013-09-24 | Hoffmann La Roche | inibidores para glyt-1 |
| WO2009105774A2 (en) * | 2008-02-21 | 2009-08-27 | Sequoia Pharmaceuticals, Inc. | Amino acid inhibitors of cytochrome p450 |
| EP2351565A1 (de) | 2008-10-20 | 2011-08-03 | Astellas Pharma Inc. | Medizin zur verhinderung oder behandlung von schmerzen aufgrund von gürtelrose |
| EP2616073A4 (de) * | 2010-09-13 | 2015-02-18 | Microbiotix Inc | Hemmer des eindringens von viren in säugetier-wirtszellen |
| WO2012073375A1 (ja) | 2010-12-03 | 2012-06-07 | 富士通株式会社 | 新規化合物、並びに、キネシンスピンドルタンパク質阻害剤及びその応用 |
| CN103275034B (zh) * | 2013-04-16 | 2015-07-08 | 南京工业大学 | 一类小分子cathepsin D抑制剂的制备方法 |
| TW202038947A (zh) | 2018-11-28 | 2020-11-01 | 德商創新分子有限責任公司 | 在與溶瘤病毒之組合療法中治療癌症的解旋酶引子酶抑制劑 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0871619T3 (da) * | 1995-12-29 | 2003-03-03 | Boehringer Ingelheim Pharma | Phenylthiazolderivater med antiherpesvirusegenskaber |
| WO1999042455A1 (en) * | 1998-02-19 | 1999-08-26 | Tularik Inc. | Antiviral agents |
| WO2000029399A1 (en) * | 1998-11-12 | 2000-05-25 | Boehringer Ingelheim (Canada) Ltd. | Antiherpes compounds |
-
2001
- 2001-11-08 KR KR10-2003-7006347A patent/KR20030045180A/ko not_active Application Discontinuation
- 2001-11-08 CN CNA018184316A patent/CN1473157A/zh active Pending
- 2001-11-08 JP JP2002541089A patent/JP3913172B2/ja not_active Expired - Fee Related
- 2001-11-08 WO PCT/JP2001/009790 patent/WO2002038554A1/ja active IP Right Grant
- 2001-11-08 ES ES01981033T patent/ES2247177T3/es not_active Expired - Lifetime
- 2001-11-08 AU AU2002212734A patent/AU2002212734A1/en not_active Abandoned
- 2001-11-08 CA CA2428184A patent/CA2428184C/en not_active Expired - Fee Related
- 2001-11-08 EP EP01981033A patent/EP1340750B8/de not_active Expired - Lifetime
- 2001-11-08 AT AT01981033T patent/ATE302197T1/de not_active IP Right Cessation
- 2001-11-08 US US10/416,371 patent/US6949543B2/en not_active Expired - Fee Related
- 2001-11-08 DE DE60112790T patent/DE60112790T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20040034232A1 (en) | 2004-02-19 |
| CA2428184C (en) | 2010-03-30 |
| ES2247177T3 (es) | 2006-03-01 |
| EP1340750A1 (de) | 2003-09-03 |
| AU2002212734A1 (en) | 2002-05-21 |
| ATE302197T1 (de) | 2005-09-15 |
| EP1340750B1 (de) | 2005-08-17 |
| JP3913172B2 (ja) | 2007-05-09 |
| CA2428184A1 (en) | 2002-05-16 |
| WO2002038554A1 (fr) | 2002-05-16 |
| DE60112790T2 (de) | 2006-05-18 |
| KR20030045180A (ko) | 2003-06-09 |
| EP1340750B8 (de) | 2005-10-19 |
| EP1340750A4 (de) | 2004-01-21 |
| JPWO2002038554A1 (ja) | 2004-03-18 |
| CN1473157A (zh) | 2004-02-04 |
| US6949543B2 (en) | 2005-09-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: RATIONAL DRUG DESIGN LABORATORIES, TOKIO/TOKYO, JP Owner name: ASTELLAS PHARMA, INC., TOKIO/TOKYO, JP |
|
| 8364 | No opposition during term of opposition |