ATE299138T1 - Mandelatsalze von substituierten tetrazyklischen tetrahydrofuranderivaten - Google Patents

Mandelatsalze von substituierten tetrazyklischen tetrahydrofuranderivaten

Info

Publication number
ATE299138T1
ATE299138T1 AT02781214T AT02781214T ATE299138T1 AT E299138 T1 ATE299138 T1 AT E299138T1 AT 02781214 T AT02781214 T AT 02781214T AT 02781214 T AT02781214 T AT 02781214T AT E299138 T1 ATE299138 T1 AT E299138T1
Authority
AT
Austria
Prior art keywords
tetrahydrofuran derivatives
substituted tetracyclic
mandelate salts
tetracyclic tetrahydrofuran
mandelate
Prior art date
Application number
AT02781214T
Other languages
English (en)
Inventor
Bart P A M J Medaer
Sigrid C M Stokbroekx
Yves G Ruysschaert
Joannes J M Willems
Johan E E Weerts
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE299138T1 publication Critical patent/ATE299138T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
AT02781214T 2001-11-09 2002-11-08 Mandelatsalze von substituierten tetrazyklischen tetrahydrofuranderivaten ATE299138T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01204465 2001-11-09
PCT/EP2002/011136 WO2003040122A1 (en) 2001-11-09 2002-11-08 Novel mandelate salts of substituted tetracyclic tetrahydrofuran derivatives

Publications (1)

Publication Number Publication Date
ATE299138T1 true ATE299138T1 (de) 2005-07-15

Family

ID=8181272

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02781214T ATE299138T1 (de) 2001-11-09 2002-11-08 Mandelatsalze von substituierten tetrazyklischen tetrahydrofuranderivaten

Country Status (25)

Country Link
US (1) US7317115B2 (de)
EP (1) EP1446397B1 (de)
JP (1) JP2005508988A (de)
KR (1) KR100962325B1 (de)
CN (1) CN1582282B (de)
AR (1) AR037285A1 (de)
AT (1) ATE299138T1 (de)
AU (1) AU2002349327B2 (de)
BR (1) BR0212770A (de)
CA (1) CA2465043C (de)
DE (1) DE60204982T2 (de)
EA (1) EA006980B1 (de)
ES (1) ES2244818T3 (de)
HR (1) HRP20040395A2 (de)
HU (1) HUP0402224A3 (de)
IL (2) IL161866A0 (de)
MX (1) MXPA04004365A (de)
MY (1) MY128237A (de)
NO (1) NO328548B1 (de)
NZ (1) NZ531739A (de)
PL (1) PL368456A1 (de)
TW (1) TW200407117A (de)
UA (1) UA79248C2 (de)
WO (1) WO2003040122A1 (de)
ZA (1) ZA200403454B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2335700A1 (de) 2001-07-25 2011-06-22 Boehringer Ingelheim (Canada) Ltd. Hepatitis C Virus Polymerase Inhibitoren mit heterobicylischer Struktur
MXPA04005400A (es) * 2001-12-07 2004-10-11 Janssen Pharmaceutica Nv Preparacion de derivados de 3,3a,8,12b-tetrahidro-2h-dibenzo(3,4:6,7(ciclohepta(1,2-b(furano trans-fusionados.
WO2005013969A1 (en) * 2003-07-15 2005-02-17 Janssen Pharmaceutica N.V. Antipsychotic agent with socializing properties
EP1824820A2 (de) 2004-12-07 2007-08-29 Janssen Pharmaceutica N.V. Substituierte derivate von tetracyclischem tetrahydrofuran, pyrrolidin und tetrahydrothiopen
EP1846415B1 (de) 2005-01-27 2012-08-01 Janssen Pharmaceutica NV Heterocyclische tetracyclische tetrahydrofuran-derivate als 5ht2-hemmer bei der behandlung von erkrankungen des zentralnervensystems
EA014104B1 (ru) 2005-06-17 2010-10-29 Янссен Фармацевтика Н.В. Новые тетрациклические производные тетрагидрофурана, содержащие боковую цепь циклического амина
US8507040B2 (en) 2008-05-08 2013-08-13 Air Products And Chemicals, Inc. Binary and ternary metal chalcogenide materials and method of making and using same
US8765223B2 (en) * 2008-05-08 2014-07-01 Air Products And Chemicals, Inc. Binary and ternary metal chalcogenide materials and method of making and using same
US8962675B1 (en) * 2013-09-12 2015-02-24 Abbvie Inc. Atrasentan mandelate salts

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3644462A1 (de) * 1986-12-24 1988-07-07 Basf Ag Verfahren zur herstellung von 5h-dibenzo(a,d)cyclohepten-5-onen
JP2656720B2 (ja) * 1992-12-09 1997-09-24 武田薬品工業株式会社 光学活性アミノクマラン誘導体
WO1995025102A1 (en) * 1994-03-16 1995-09-21 Novo Nordisk A/S Acid addition salts of 2,3,4,5-tetrahydro-1h-3-benzazepine compounds
TR199801164T2 (xx) * 1996-04-12 1998-10-21 Janssen Pharmaceutica N.V. S�bstit�e edilmi� tetrasiklik tetrahidrofuran t�revleri.
ATE255883T1 (de) 1996-05-20 2003-12-15 Janssen Pharmaceutica Nv Fungizide mittel mit verbesserter bioverfügbarkeit
UA52778C2 (uk) * 1997-10-10 2003-01-15 Янссен Фармацевтика Н.В. Галогенозаміщені тетрациклічні похідні тетрагідрофурану, спосіб їх отримання та композиція на їх основі
US6281247B1 (en) * 1998-03-03 2001-08-28 Novo Nordisk A/S Salt forms of (2E)-5-amino-5-methylhex-2-enoic acid N-methyl-N-((1R)-1-(N-methyl-N-((1R)-1-(methylcarbamoyl)-2-phenylethyl)carbamoyl)-2-(2-naphthyl)ethyl)amide
HUP9904624A2 (hu) * 1999-12-17 2002-01-28 Sanofi-Synthelabo Szacharinszármazékok, eljárás előállításukra, az ezeket tartalmazó gyógyszerkészítmények és intermedierjeik
EP1186303A3 (de) * 2000-09-06 2003-12-10 Pfizer Products Inc. Ein Neutrophilhemmender Faktor und ein selektive NMDA-NR2B Rezeptor Antagonisten enthaltende Kombinationspräparate zur Behandlung von Schlaganfällen und traumatischen Gehirnschäden

Also Published As

Publication number Publication date
HRP20040395A2 (en) 2005-04-30
EA200400656A1 (ru) 2004-10-28
ES2244818T3 (es) 2005-12-16
HUP0402224A3 (en) 2007-05-29
KR20050044310A (ko) 2005-05-12
KR100962325B1 (ko) 2010-06-11
NO20041848L (no) 2004-05-05
NZ531739A (en) 2005-02-25
IL161866A (en) 2010-04-29
CA2465043A1 (en) 2003-05-15
US20050085533A1 (en) 2005-04-21
CA2465043C (en) 2011-02-15
CN1582282A (zh) 2005-02-16
ZA200403454B (en) 2005-08-31
MXPA04004365A (es) 2004-08-11
WO2003040122A1 (en) 2003-05-15
IL161866A0 (en) 2005-11-20
EP1446397A1 (de) 2004-08-18
BR0212770A (pt) 2004-10-13
CN1582282B (zh) 2012-06-06
JP2005508988A (ja) 2005-04-07
US7317115B2 (en) 2008-01-08
AR037285A1 (es) 2004-11-03
MY128237A (en) 2007-01-31
NO328548B1 (no) 2010-03-15
DE60204982D1 (de) 2005-08-11
UA79248C2 (en) 2007-06-11
HUP0402224A2 (hu) 2005-02-28
DE60204982T2 (de) 2006-04-27
EP1446397B1 (de) 2005-07-06
AU2002349327B2 (en) 2008-10-23
TW200407117A (en) 2004-05-16
PL368456A1 (en) 2005-03-21
EA006980B1 (ru) 2006-06-30

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Legal Events

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