ATE296124T1 - Haut/haar-äquivalent mit rekonstruierten papillen - Google Patents

Haut/haar-äquivalent mit rekonstruierten papillen

Info

Publication number
ATE296124T1
ATE296124T1 AT02804895T AT02804895T ATE296124T1 AT E296124 T1 ATE296124 T1 AT E296124T1 AT 02804895 T AT02804895 T AT 02804895T AT 02804895 T AT02804895 T AT 02804895T AT E296124 T1 ATE296124 T1 AT E296124T1
Authority
AT
Austria
Prior art keywords
reconstructed
skin
papillas
hair equivalent
hair
Prior art date
Application number
AT02804895T
Other languages
English (en)
Inventor
Kordula Schlotmann
Thomas Gassenmeier
Ralf Paus
Melanie Giesen
Dirk Petersohn
Original Assignee
Henkel Kgaa
Cutech S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7710083&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE296124(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Henkel Kgaa, Cutech S R L filed Critical Henkel Kgaa
Application granted granted Critical
Publication of ATE296124T1 publication Critical patent/ATE296124T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0627—Hair cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/10—Hair or skin implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C12N5/0698—Skin equivalents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/18—Materials or treatment for tissue regeneration for hair reconstruction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
    • C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323—Adult fibroblasts

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Botany (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT02804895T 2001-12-19 2002-12-13 Haut/haar-äquivalent mit rekonstruierten papillen ATE296124T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10162814A DE10162814B4 (de) 2001-12-19 2001-12-19 Rekonstruiertes Haarfollikelmodell
PCT/EP2002/014212 WO2003051419A1 (en) 2001-12-19 2002-12-13 Skin/hair equivalent with reconstructed papillae

Publications (1)

Publication Number Publication Date
ATE296124T1 true ATE296124T1 (de) 2005-06-15

Family

ID=7710083

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02804895T ATE296124T1 (de) 2001-12-19 2002-12-13 Haut/haar-äquivalent mit rekonstruierten papillen

Country Status (7)

Country Link
EP (1) EP1455854B1 (de)
JP (1) JP2005525088A (de)
AT (1) ATE296124T1 (de)
AU (1) AU2002366280A1 (de)
DE (2) DE10162814B4 (de)
ES (1) ES2243801T3 (de)
WO (1) WO2003051419A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005033302A1 (ja) * 2003-10-06 2005-04-14 Shiseido Company, Ltd. 毛乳頭細胞調製品の調製方法、毛包を再生するための組成物、方法及び再生された毛包を担持する動物
US20080089873A1 (en) * 2004-06-14 2008-04-17 Shiseido Company, Ltd. Method for Regenerating Hair Follicles by Suppressing a Gene with Hair Follicle Formation-Inhibiting Ability or by Activating a Gene with Hair Follicle Formation-Inducing Ability
KR100616752B1 (ko) 2004-11-29 2006-08-31 박정극 모낭 유도 능력이 있는 모유두 조직의 제조방법
US8846393B2 (en) 2005-11-29 2014-09-30 Gamida-Cell Ltd. Methods of improving stem cell homing and engraftment
GB0605450D0 (en) * 2006-03-17 2006-04-26 Intercytex Ltd Cell co-culture
FR2903702B1 (fr) * 2006-07-13 2012-10-19 Oreal Equivalent d'epiderme capable de se pigmenter obtenu a partir de cellules de la matrice, procede de preparation et utilisation
DE102006043767A1 (de) 2006-09-13 2008-03-27 Henkel Kgaa Extrakt aus Apium graveleons zur Stimulierung des Haarwuchses
GB2442271B (en) * 2006-09-27 2011-06-15 Denis Eon Solomon An in vitro human skin assay protocol which directly uses the natural cellular interactions between un-manipulated autologous human epidermal and dermal cells
JP5097387B2 (ja) * 2006-11-16 2012-12-12 ライオン株式会社 人工皮膚
DE102007032393A1 (de) 2007-07-10 2009-01-29 Henkel Ag & Co. Kgaa Advanced Glycation Endproducts als Wirkstoffe
DE102007048409A1 (de) * 2007-10-09 2009-04-16 Carl Zeiss Microimaging Gmbh Verfahren zum Positionieren von biologischen Proben in einer mikroskopischen Anordnung
EP2105499A1 (de) 2008-03-28 2009-09-30 Technische Universität Berlin Verfahren zum Herstellen von Novo Papillae und Haarmikrofollikeln und ihre Verwendung bei In-vitro-Tests und in-vivo-Implantationen
DE102009043486A1 (de) 2009-09-30 2010-07-01 Henkel Ag & Co. Kgaa Verwendung von Wirkstoffen, erhältlich aus Pflanzen, zur Verhinderung und/oder Verminderung der Auswirkungen von psychoemotionalem Stress auf das Haar
KR101859500B1 (ko) 2010-12-01 2018-05-21 (주)아모레퍼시픽 3차원 매트릭스
FR2976001B1 (fr) 2011-05-30 2014-10-31 Oreal Modele de cuir chevelu reconstruit et procede de screening de molecules actives
CN104204192A (zh) 2012-02-13 2014-12-10 加米达细胞有限公司 间充质干细胞调理的基质及其产生和使用方法
US9567569B2 (en) 2012-07-23 2017-02-14 Gamida Cell Ltd. Methods of culturing and expanding mesenchymal stem cells
US9175266B2 (en) 2012-07-23 2015-11-03 Gamida Cell Ltd. Enhancement of natural killer (NK) cell proliferation and activity
DE102012220154A1 (de) 2012-11-06 2014-05-08 Henkel Ag & Co. Kgaa Mund- und Zahnpflege- und -reinigungsmittel mit Vitamin E
JP2014204711A (ja) * 2013-03-19 2014-10-30 国立大学法人 千葉大学 三次元培養皮膚モデルの製造方法およびその利用
JP6469655B2 (ja) * 2013-05-03 2019-02-13 ザ ヘンリー エム． ジャクソン ファウンデーション フォー ザ アドヴァンスメント オブ ミリタリー メディシン インコーポレイテッド 代用皮膚および毛包新生の方法
CN103721294B (zh) * 2013-12-27 2015-05-13 太原理工大学 一种人体表皮组织的快速构建制备方法
DE102014212921A1 (de) 2014-07-03 2016-01-07 Henkel Ag & Co. Kgaa Verwendung von speziellen Oligopeptiden zur Stimulierung des natürlichen Pigmentierungsprozesses in Hautanhangsgebilden
CN104195101B (zh) * 2014-09-09 2016-04-13 武斌 一种毛囊单位保存培养液
CN104491931B (zh) * 2014-12-02 2017-04-12 清华大学深圳研究生院 含有皮脂腺的皮肤组织及其形成方法和用途
CN108367099B (zh) * 2015-10-21 2021-11-23 印第安纳大学研究与技术公司 来自多能干细胞的人皮肤类器官的衍生
CN108291197B (zh) 2015-10-21 2022-09-16 印第安纳大学研究与技术公司 生成人内耳感觉上皮和感觉神经元的方法
DE102015119877B4 (de) 2015-11-17 2017-09-21 Technische Universität Berlin Verfahren zur Herstellung eines Hautäquivalents sowie dessen Verwendung für in vitro Tests und in vivo Transplantate
SG11201811102XA (en) * 2016-06-21 2019-01-30 Organ Technologies Inc Method for producing artificial skin having hair follicles, sebaceous glands, and pores
CN109735486B (zh) * 2019-01-31 2022-02-22 中国疾病预防控制中心辐射防护与核安全医学所 一种用于研究uvb照射致早衰的原代黑素细胞培养方法
CN112300981A (zh) * 2020-11-14 2021-02-02 厦门思明银河整形外科门诊部有限公司 一种体外培养毛囊的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8604360D0 (en) * 1986-02-21 1986-03-26 Univ Dundee Stimulation of hair growth
FR2612938B1 (fr) * 1987-03-26 1989-06-23 Cird Procede d'obtention d'un equivalent de peau et equivalent de peau correspondant
WO1997025995A1 (en) * 1996-01-18 1997-07-24 Johnson & Johnson Consumer Products, Inc. Methods for regenerating scarless skin and compositions used therein
CA2253724A1 (en) * 1996-04-26 1997-11-06 Case Western Reserve University Skin regeneration using mesenchymal stem cells
WO1999001034A1 (en) * 1997-07-01 1999-01-14 Cooley Jerry E Method for producing new hair growth
WO2000029553A1 (en) * 1998-11-19 2000-05-25 Organogenesis Inc. Bioengineered tissue constructs and methods for producing and using them
EP1005873B1 (de) * 1998-11-30 2003-04-09 IsoTis N.V. Kunsthaut

Also Published As

Publication number Publication date
DE10162814A1 (de) 2003-07-10
DE10162814B4 (de) 2005-06-23
WO2003051419A1 (en) 2003-06-26
JP2005525088A (ja) 2005-08-25
ES2243801T3 (es) 2005-12-01
DE60204352T2 (de) 2006-01-26
AU2002366280A1 (en) 2003-06-30
EP1455854B1 (de) 2005-05-25
DE60204352D1 (de) 2005-06-30
EP1455854A1 (de) 2004-09-15

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