DE60322871D1 - Thaltende zubereitungen - Google Patents

Thaltende zubereitungen

Info

Publication number
DE60322871D1
DE60322871D1 DE60322871T DE60322871T DE60322871D1 DE 60322871 D1 DE60322871 D1 DE 60322871D1 DE 60322871 T DE60322871 T DE 60322871T DE 60322871 T DE60322871 T DE 60322871T DE 60322871 D1 DE60322871 D1 DE 60322871D1
Authority
DE
Germany
Prior art keywords
thinking
preparations
adhyperforin
hyperforin
alzheimer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60322871T
Other languages
English (en)
Inventor
Ezio Bombardelli
Paolo Morazzoni
Antonella Riva
Nicola Fuzzati
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Indena SpA
Original Assignee
Indena SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena SpA filed Critical Indena SpA
Application granted granted Critical
Publication of DE60322871D1 publication Critical patent/DE60322871D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/013—Esters of alcohols having the esterified hydroxy group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/64—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/713—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups a keto group being part of a six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/723—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic
    • C07C49/727—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
    • C07C49/733—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system having two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/743—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups having unsaturation outside the rings, e.g. humulones, lupulones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/46—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing nine carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
  • Semiconductor Lasers (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE60322871T 2002-04-23 2003-04-18 Thaltende zubereitungen Expired - Lifetime DE60322871D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2002MI000872A ITMI20020872A1 (it) 2002-04-23 2002-04-23 Derivati dell'iperforina loro uso e formulazioni che li contengono
PCT/EP2003/004100 WO2003091194A1 (en) 2002-04-23 2003-04-18 Hyperforin derivatives, the use thereof and formulations containing them

Publications (1)

Publication Number Publication Date
DE60322871D1 true DE60322871D1 (de) 2008-09-25

Family

ID=11449767

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60322871T Expired - Lifetime DE60322871D1 (de) 2002-04-23 2003-04-18 Thaltende zubereitungen

Country Status (19)

Country Link
US (2) US7105705B2 (de)
EP (1) EP1497250B1 (de)
JP (1) JP4315818B2 (de)
KR (1) KR100944052B1 (de)
CN (1) CN1290816C (de)
AT (1) ATE404519T1 (de)
CA (1) CA2483205C (de)
DE (1) DE60322871D1 (de)
DK (1) DK1497250T3 (de)
ES (1) ES2311697T3 (de)
HK (1) HK1075654A1 (de)
IL (1) IL164763A (de)
IT (1) ITMI20020872A1 (de)
NO (1) NO329176B1 (de)
PL (1) PL205829B1 (de)
PT (1) PT1497250E (de)
RU (1) RU2320636C2 (de)
SI (1) SI1497250T1 (de)
WO (1) WO2003091194A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102772461B (zh) * 2011-05-11 2014-05-14 成都康弘药业集团股份有限公司 药物组合物在制备预防或治疗老年性痴呆的药物中的应用
KR20140041610A (ko) * 2011-06-03 2014-04-04 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 하이퍼포린 유사체, 합성 방법 및 그의 용도
ITMI20131012A1 (it) 2013-06-19 2014-12-20 Indena Spa Derivati dell'iperforina e loro uso nella malattia di alzheimer
US20180071269A1 (en) 2015-08-12 2018-03-15 Tianxin Wang Therapeutical methods, formulations and nutraceutical formulations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999040905A2 (de) 1998-02-13 1999-08-19 Dr. Willmar Schwabe Gmbh & Co. Verwendung von hyperforin und hyperforinhaltigen extrakten zur behandlung und prophylaxe von demenzerkrankungen
CA2320091A1 (en) * 1998-02-13 1999-08-19 Dr. Willmar Schwabe Gmbh & Co. Stable hyperforin salts, methods of manufacturing them, and their use for the treatment of alzheimer's disease
IT1301679B1 (it) 1998-06-10 2000-07-07 Indena Spa Derivati dell'iperforina, loro uso e formulazioni che licontengono.

Also Published As

Publication number Publication date
ES2311697T3 (es) 2009-02-16
KR100944052B1 (ko) 2010-02-24
IL164763A0 (en) 2005-12-18
CA2483205C (en) 2011-07-05
ITMI20020872A0 (it) 2002-04-23
US20050165117A1 (en) 2005-07-28
RU2004131210A (ru) 2005-04-10
HK1075654A1 (en) 2005-12-23
ATE404519T1 (de) 2008-08-15
ITMI20020872A1 (it) 2003-10-23
CA2483205A1 (en) 2003-11-06
PL205829B1 (pl) 2010-05-31
CN1290816C (zh) 2006-12-20
SI1497250T1 (sl) 2008-12-31
IL164763A (en) 2010-02-17
CN1646462A (zh) 2005-07-27
PL371347A1 (en) 2005-06-13
US7105705B2 (en) 2006-09-12
AU2003222828A1 (en) 2003-11-10
PT1497250E (pt) 2008-11-12
JP4315818B2 (ja) 2009-08-19
USRE43280E1 (en) 2012-03-27
WO2003091194A1 (en) 2003-11-06
NO329176B1 (no) 2010-09-06
JP2005523917A (ja) 2005-08-11
KR20040111519A (ko) 2004-12-31
NO20044519L (no) 2004-11-02
EP1497250A1 (de) 2005-01-19
RU2320636C2 (ru) 2008-03-27
DK1497250T3 (da) 2008-12-01
EP1497250B1 (de) 2008-08-13

Similar Documents

Publication Publication Date Title
AU2002233288A1 (en) Combined use of Enzyme Inhibitors and Pharmaceutical Preparations thereof for the Treatment and Prophylaxis of Arteriosclerosis, for the Treatment and Prevention of Allergic Reactions of Type I According to the Gell and Coombs Classification, and for the Treatment and Prevention of Dermatological Diseases Associated with FO
ATE309798T1 (de) Pharmazeutische zusammensetzungen enthaltend cannabidiol-derivate
IL154888A (en) Aqueous Pharmaceutical Gel Preparation Containing At least One Vitamin D or One Vitamin D Analog At least One Corticosteroid
DE60100866D1 (de) Cyklosporin, Hyaluronsäure und Polysorbate enthaltenes Augenarzneimittel
BRPI0407662B8 (pt) derivados do ácido 1-fenilalcanocarboxílico para o tratamento de doenças neurodegenerativas
DE60235719D1 (de) Frauenhygieneartikel zur verabreichung von arzneimittel
EP1578421A4 (de) Pharmazeutische präparate für diebehandlung von erkrankungen und pathologischen zuständen der brust
MX9605940A (es) Compuestos bioaromaticos que llevan un grupo adamantilo en orto, composiciones farmaceuticas y cosmeticas que los contienen y utilizaciones.
MX9708800A (es) Compuestos biciclicos aromaticos.
ZA200501714B (en) Analogues of vitamin d
HK1068606A1 (en) Novel aminobenzoephenones
JP2005511619A5 (de)
GEP20063869B (en) Novel cyclohexyl sulphones
HK1075654A1 (en) Hyperforin derivatives, the use thereof and formulations containing them
MY130445A (en) Novel formulations of alpha-2, 4-disulfophenyl-n-tert-butylnitrone
BR0116653A (pt) Medicamento contendo uma poliamina como substância ativa
NO995838L (no) Nye heteroetynylenforbindelser og farmasoeytiske og kosmetiske preparater inneholdende de samme
ITMI20021866A1 (it) Preparazione farmaceutica in forma colloidale utile nella cura delle affezioni cutanee.
AR030945A1 (es) Amidas de acido fenilciclohexanocarboxilico sustituido y su uso
ATE241640T1 (de) Fusidinsäure-derivate
HUP0204180A2 (hu) Külsőleges készítmény és alkalmazása allergiás dermatitisz kezelésére
IT1317818B1 (it) Procedimento per la produzione di componenti per integratorialimentari, formulazioni dietetiche, cosmetiche e farmaceutiche,
DE50304524D1 (de) Arzneimittel enthaltend substituierte 2,5-diaminomethyl-1h-pyrrole
NO20033118L (no) Mikanolide-derivater, farmasoytiske preparater inneholdende slike samt anvendelse av slike for fremstilling av medikamenter for behandling av sykdom
UA37445A (uk) Протизапальний засіб

Legal Events

Date Code Title Description
8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC

8364 No opposition during term of opposition