DK1497250T3 - Hyperforinderivater, anvendelse heraf og sammensætninger indeholdende disse - Google Patents
Hyperforinderivater, anvendelse heraf og sammensætninger indeholdende disseInfo
- Publication number
- DK1497250T3 DK1497250T3 DK03718778T DK03718778T DK1497250T3 DK 1497250 T3 DK1497250 T3 DK 1497250T3 DK 03718778 T DK03718778 T DK 03718778T DK 03718778 T DK03718778 T DK 03718778T DK 1497250 T3 DK1497250 T3 DK 1497250T3
- Authority
- DK
- Denmark
- Prior art keywords
- compositions containing
- hyperforin
- hyperforin derivatives
- derivatives
- adhyperforin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/013—Esters of alcohols having the esterified hydroxy group bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/64—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/713—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups a keto group being part of a six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/723—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic
- C07C49/727—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
- C07C49/733—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system having two rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/743—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups having unsaturation outside the rings, e.g. humulones, lupulones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
- C07C2602/46—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing nine carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Alternative & Traditional Medicine (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Peptides Or Proteins (AREA)
- Semiconductor Lasers (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2002MI000872A ITMI20020872A1 (it) | 2002-04-23 | 2002-04-23 | Derivati dell'iperforina loro uso e formulazioni che li contengono |
| PCT/EP2003/004100 WO2003091194A1 (en) | 2002-04-23 | 2003-04-18 | Hyperforin derivatives, the use thereof and formulations containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1497250T3 true DK1497250T3 (da) | 2008-12-01 |
Family
ID=11449767
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03718778T DK1497250T3 (da) | 2002-04-23 | 2003-04-18 | Hyperforinderivater, anvendelse heraf og sammensætninger indeholdende disse |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | USRE43280E1 (da) |
| EP (1) | EP1497250B1 (da) |
| JP (1) | JP4315818B2 (da) |
| KR (1) | KR100944052B1 (da) |
| CN (1) | CN1290816C (da) |
| AT (1) | ATE404519T1 (da) |
| CA (1) | CA2483205C (da) |
| DE (1) | DE60322871D1 (da) |
| DK (1) | DK1497250T3 (da) |
| ES (1) | ES2311697T3 (da) |
| HK (1) | HK1075654A1 (da) |
| IL (1) | IL164763A (da) |
| IT (1) | ITMI20020872A1 (da) |
| NO (1) | NO329176B1 (da) |
| PL (1) | PL205829B1 (da) |
| PT (1) | PT1497250E (da) |
| RU (1) | RU2320636C2 (da) |
| SI (1) | SI1497250T1 (da) |
| WO (1) | WO2003091194A1 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102772461B (zh) * | 2011-05-11 | 2014-05-14 | 成都康弘药业集团股份有限公司 | 药物组合物在制备预防或治疗老年性痴呆的药物中的应用 |
| CA2837549A1 (en) * | 2011-06-03 | 2012-12-06 | President And Fellows Of Harvard College | Hyperforin analogs, methods of synthesis, and uses thereof |
| ITMI20131012A1 (it) * | 2013-06-19 | 2014-12-20 | Indena Spa | Derivati dell'iperforina e loro uso nella malattia di alzheimer |
| US20180071269A1 (en) | 2015-08-12 | 2018-03-15 | Tianxin Wang | Therapeutical methods, formulations and nutraceutical formulations |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999040905A2 (de) | 1998-02-13 | 1999-08-19 | Dr. Willmar Schwabe Gmbh & Co. | Verwendung von hyperforin und hyperforinhaltigen extrakten zur behandlung und prophylaxe von demenzerkrankungen |
| JP2002503646A (ja) | 1998-02-13 | 2002-02-05 | ドクトル．ヴイルマル シュヴアベ ゲーエムベーハーウント コンパニー | 安定なハイパーフォリン塩、それらの製造方法、及びそれらのアルツハイマー病の治療のための使用 |
| IT1301679B1 (it) | 1998-06-10 | 2000-07-07 | Indena Spa | Derivati dell'iperforina, loro uso e formulazioni che licontengono. |
-
2002
- 2002-04-23 IT IT2002MI000872A patent/ITMI20020872A1/it unknown
-
2003
- 2003-04-18 DE DE60322871T patent/DE60322871D1/de not_active Expired - Lifetime
- 2003-04-18 DK DK03718778T patent/DK1497250T3/da active
- 2003-04-18 PT PT03718778T patent/PT1497250E/pt unknown
- 2003-04-18 EP EP03718778A patent/EP1497250B1/en not_active Expired - Lifetime
- 2003-04-18 WO PCT/EP2003/004100 patent/WO2003091194A1/en active IP Right Grant
- 2003-04-18 US US12/896,158 patent/USRE43280E1/en not_active Expired - Fee Related
- 2003-04-18 PL PL371347A patent/PL205829B1/pl unknown
- 2003-04-18 JP JP2003587762A patent/JP4315818B2/ja not_active Expired - Fee Related
- 2003-04-18 RU RU2004131210/04A patent/RU2320636C2/ru not_active IP Right Cessation
- 2003-04-18 US US10/512,067 patent/US7105705B2/en not_active Ceased
- 2003-04-18 AT AT03718778T patent/ATE404519T1/de active
- 2003-04-18 CN CNB038089319A patent/CN1290816C/zh not_active Expired - Fee Related
- 2003-04-18 ES ES03718778T patent/ES2311697T3/es not_active Expired - Lifetime
- 2003-04-18 CA CA2483205A patent/CA2483205C/en not_active Expired - Fee Related
- 2003-04-18 KR KR1020047016491A patent/KR100944052B1/ko not_active IP Right Cessation
- 2003-04-18 SI SI200331386T patent/SI1497250T1/sl unknown
-
2004
- 2004-10-21 NO NO20044519A patent/NO329176B1/no not_active IP Right Cessation
- 2004-10-21 IL IL164763A patent/IL164763A/en not_active IP Right Cessation
-
2005
- 2005-09-05 HK HK05107783A patent/HK1075654A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003222828A1 (en) | 2003-11-10 |
| US7105705B2 (en) | 2006-09-12 |
| EP1497250B1 (en) | 2008-08-13 |
| US20050165117A1 (en) | 2005-07-28 |
| USRE43280E1 (en) | 2012-03-27 |
| ES2311697T3 (es) | 2009-02-16 |
| SI1497250T1 (sl) | 2008-12-31 |
| JP4315818B2 (ja) | 2009-08-19 |
| CN1290816C (zh) | 2006-12-20 |
| RU2004131210A (ru) | 2005-04-10 |
| KR20040111519A (ko) | 2004-12-31 |
| ITMI20020872A1 (it) | 2003-10-23 |
| DE60322871D1 (de) | 2008-09-25 |
| CA2483205C (en) | 2011-07-05 |
| CA2483205A1 (en) | 2003-11-06 |
| PL371347A1 (en) | 2005-06-13 |
| PL205829B1 (pl) | 2010-05-31 |
| JP2005523917A (ja) | 2005-08-11 |
| PT1497250E (pt) | 2008-11-12 |
| RU2320636C2 (ru) | 2008-03-27 |
| CN1646462A (zh) | 2005-07-27 |
| ATE404519T1 (de) | 2008-08-15 |
| IL164763A (en) | 2010-02-17 |
| EP1497250A1 (en) | 2005-01-19 |
| HK1075654A1 (en) | 2005-12-23 |
| NO20044519L (no) | 2004-11-02 |
| IL164763A0 (en) | 2005-12-18 |
| WO2003091194A1 (en) | 2003-11-06 |
| NO329176B1 (no) | 2010-09-06 |
| KR100944052B1 (ko) | 2010-02-24 |
| ITMI20020872A0 (it) | 2002-04-23 |
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