ATE289299T1 - Polyzyclisch aryl und heteroaryl substituierte 4- pyronen verwendbar als selektive hemmung von dem koagulationsprozess - Google Patents
Polyzyclisch aryl und heteroaryl substituierte 4- pyronen verwendbar als selektive hemmung von dem koagulationsprozessInfo
- Publication number
- ATE289299T1 ATE289299T1 AT01923149T AT01923149T ATE289299T1 AT E289299 T1 ATE289299 T1 AT E289299T1 AT 01923149 T AT01923149 T AT 01923149T AT 01923149 T AT01923149 T AT 01923149T AT E289299 T1 ATE289299 T1 AT E289299T1
- Authority
- AT
- Austria
- Prior art keywords
- heteroaryl substituted
- polycyclic aryl
- pyrones
- usable
- selective inhibition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/40—Oxygen atoms attached in positions 3 and 4, e.g. maltol
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19491500P | 2000-04-05 | 2000-04-05 | |
US25215700P | 2000-11-20 | 2000-11-20 | |
PCT/US2001/011013 WO2001077097A2 (en) | 2000-04-05 | 2001-04-04 | Polycyclic aryl and heteroaryl substituted 4-pyrones useful for selective inhibition of the coagulation cascade |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE289299T1 true ATE289299T1 (de) | 2005-03-15 |
Family
ID=26890524
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01923149T ATE289299T1 (de) | 2000-04-05 | 2001-04-04 | Polyzyclisch aryl und heteroaryl substituierte 4- pyronen verwendbar als selektive hemmung von dem koagulationsprozess |
Country Status (10)
Country | Link |
---|---|
US (4) | US6875791B2 (de) |
EP (1) | EP1268463B1 (de) |
JP (1) | JP2004505014A (de) |
AT (1) | ATE289299T1 (de) |
AU (1) | AU2001249870A1 (de) |
CA (1) | CA2405561A1 (de) |
DE (1) | DE60108948T2 (de) |
ES (1) | ES2236211T3 (de) |
PT (1) | PT1268463E (de) |
WO (1) | WO2001077097A2 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6660885B2 (en) | 2000-03-13 | 2003-12-09 | Pharmacia Corporation | Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade |
ATE289299T1 (de) | 2000-04-05 | 2005-03-15 | Pharmacia Corp | Polyzyclisch aryl und heteroaryl substituierte 4- pyronen verwendbar als selektive hemmung von dem koagulationsprozess |
US7119094B1 (en) | 2000-11-20 | 2006-10-10 | Warner-Lambert Company | Substituted polycyclic aryl and heteroarpyl pyrazinones useful for selective inhibition of the coagulation cascade |
US6624180B2 (en) * | 2000-11-20 | 2003-09-23 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyridines useful for selective inhibition of the coagulation cascade |
US7015223B1 (en) | 2000-11-20 | 2006-03-21 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl 1,2,4-triazinones useful for selective inhibition of the coagulation cascade |
WO2003093242A2 (en) | 2001-10-03 | 2003-11-13 | Pharmacia Corporation | Substituted 5-membered polycyclic compounds useful for selective inhibition of the coagulation cascade |
BR0213092A (pt) | 2001-10-03 | 2004-10-19 | Pharmacia Corp | Compostos heterocìclicos de 6 elementos úteis para a inibição seletiva da cascata de coagulação |
US8753124B2 (en) * | 2009-02-15 | 2014-06-17 | Cheryl Lynn Evans | Method and apparatus for prescribing and preparing a reproducible and customized dysphagia diet |
WO2015085238A1 (en) * | 2013-12-05 | 2015-06-11 | The Regents Of The University Of California, A California Corporation | Inhibitors of lpxc |
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JPS5910541A (ja) | 1982-07-09 | 1984-01-20 | Takeda Chem Ind Ltd | キノン化合物 |
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ES2079068T3 (es) * | 1990-06-29 | 1996-01-01 | Upjohn Co | 2-amino-6-fenil-4h-piran-4-onas antiateroscleroticas y antitromboticas. |
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WO2000039102A1 (en) | 1998-12-23 | 2000-07-06 | Du Pont Pharmaceuticals Company | THROMBIN OR FACTOR Xa INHIBITORS |
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AU771928B2 (en) | 1999-05-19 | 2004-04-08 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyridones useful for selective inhibition of the coagulation cascade |
BR0011273A (pt) | 1999-05-19 | 2002-06-18 | Pharmacia Corp | Uracilas de heteroarila e arila policìclica substituìdas como agentes anti-coagulantes |
ATE289299T1 (de) | 2000-04-05 | 2005-03-15 | Pharmacia Corp | Polyzyclisch aryl und heteroaryl substituierte 4- pyronen verwendbar als selektive hemmung von dem koagulationsprozess |
-
2001
- 2001-04-04 AT AT01923149T patent/ATE289299T1/de not_active IP Right Cessation
- 2001-04-04 WO PCT/US2001/011013 patent/WO2001077097A2/en active IP Right Grant
- 2001-04-04 US US10/240,818 patent/US6875791B2/en not_active Expired - Fee Related
- 2001-04-04 US US09/826,432 patent/US20020022604A1/en not_active Abandoned
- 2001-04-04 EP EP01923149A patent/EP1268463B1/de not_active Expired - Lifetime
- 2001-04-04 DE DE60108948T patent/DE60108948T2/de not_active Expired - Fee Related
- 2001-04-04 CA CA002405561A patent/CA2405561A1/en not_active Abandoned
- 2001-04-04 ES ES01923149T patent/ES2236211T3/es not_active Expired - Lifetime
- 2001-04-04 JP JP2001575571A patent/JP2004505014A/ja not_active Withdrawn
- 2001-04-04 AU AU2001249870A patent/AU2001249870A1/en not_active Abandoned
- 2001-04-04 PT PT01923149T patent/PT1268463E/pt unknown
-
2003
- 2003-05-14 US US10/438,077 patent/US6916847B2/en not_active Expired - Fee Related
-
2005
- 2005-03-04 US US11/072,595 patent/US20050165021A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2405561A1 (en) | 2001-10-18 |
WO2001077097A2 (en) | 2001-10-18 |
US20020022604A1 (en) | 2002-02-21 |
US6916847B2 (en) | 2005-07-12 |
PT1268463E (pt) | 2005-05-31 |
WO2001077097A3 (en) | 2002-07-04 |
EP1268463B1 (de) | 2005-02-16 |
US6875791B2 (en) | 2005-04-05 |
DE60108948D1 (de) | 2005-03-24 |
US20050165021A1 (en) | 2005-07-28 |
DE60108948T2 (de) | 2005-11-03 |
AU2001249870A1 (en) | 2001-10-23 |
US20040006227A1 (en) | 2004-01-08 |
US20030216451A1 (en) | 2003-11-20 |
EP1268463A2 (de) | 2003-01-02 |
ES2236211T3 (es) | 2005-07-16 |
JP2004505014A (ja) | 2004-02-19 |
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