ATE283689T1 - Arzneistoffabgabe in den dünndarm und den dickdarm unter verwendung von hpmc-kapseln - Google Patents

Arzneistoffabgabe in den dünndarm und den dickdarm unter verwendung von hpmc-kapseln

Info

Publication number
ATE283689T1
ATE283689T1 AT99949822T AT99949822T ATE283689T1 AT E283689 T1 ATE283689 T1 AT E283689T1 AT 99949822 T AT99949822 T AT 99949822T AT 99949822 T AT99949822 T AT 99949822T AT E283689 T1 ATE283689 T1 AT E283689T1
Authority
AT
Austria
Prior art keywords
drug delivery
small
large intestine
hpmc capsules
drug
Prior art date
Application number
AT99949822T
Other languages
English (en)
Inventor
Ewart Thomas Cole
Robert Anthony Scott
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of ATE283689T1 publication Critical patent/ATE283689T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891Coated capsules; Multilayered drug free capsule shells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fertilizers (AREA)
AT99949822T 1998-09-28 1999-09-23 Arzneistoffabgabe in den dünndarm und den dickdarm unter verwendung von hpmc-kapseln ATE283689T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10201798P 1998-09-28 1998-09-28
PCT/US1999/022117 WO2000018377A1 (en) 1998-09-28 1999-09-23 Enteric and colonic delivery using hpmc capsules

Publications (1)

Publication Number Publication Date
ATE283689T1 true ATE283689T1 (de) 2004-12-15

Family

ID=22287676

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99949822T ATE283689T1 (de) 1998-09-28 1999-09-23 Arzneistoffabgabe in den dünndarm und den dickdarm unter verwendung von hpmc-kapseln

Country Status (14)

Country Link
US (1) US7094425B2 (de)
EP (1) EP1117386B1 (de)
JP (1) JP5068401B2 (de)
KR (1) KR100695562B1 (de)
CN (1) CN100358509C (de)
AT (1) ATE283689T1 (de)
AU (1) AU757343B2 (de)
CA (1) CA2344680C (de)
DE (1) DE69922394T2 (de)
ES (1) ES2234306T3 (de)
ID (1) ID28275A (de)
MX (1) MXPA01003197A (de)
PT (1) PT1117386E (de)
WO (1) WO2000018377A1 (de)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0000773D0 (sv) * 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
SE0000774D0 (sv) 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
US7115565B2 (en) 2001-01-18 2006-10-03 Pharmacia & Upjohn Company Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability
US6645946B1 (en) 2001-03-27 2003-11-11 Pro-Pharmaceuticals, Inc. Delivery of a therapeutic agent in a formulation for reduced toxicity
US7012068B2 (en) 2001-03-27 2006-03-14 Pro-Pharmaceuticals, Inc. Co-administration of a polysaccharide with a chemotherapeutic agent for the treatment of cancer
EP2260837A1 (de) * 2001-06-01 2010-12-15 Pozen, Inc. Pharmazeutische Zusammensetzungen für die koordinierte Abgabe von NSAID
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
SE0102993D0 (sv) 2001-09-07 2001-09-07 Astrazeneca Ab New self emulsifying drug delivery system
EP1350507A1 (de) * 2002-04-04 2003-10-08 Applied NanoSystems B.V. Verabreichung einer Substanz in einen vorbestimmten Zielort
AU2003250250B2 (en) 2002-06-19 2008-02-14 Intrexon Actobiotics Nv Methods and means to promote gut absorption
US7485322B2 (en) * 2002-12-24 2009-02-03 Lek Pharmaceuticals D.D. Modified release pharmaceutical composition
US7825106B2 (en) 2003-09-03 2010-11-02 Agi Therapeutics Ltd. Modified release formulations and methods of treating inflammatory bowel disease
US7737133B2 (en) 2003-09-03 2010-06-15 Agi Therapeutics Ltd. Formulations and methods of treating inflammatory bowel disease
CN101257892B (zh) 2005-05-18 2013-01-02 达沃尔泰拉公司 吸附剂的结肠递送
US20070082046A1 (en) * 2005-10-11 2007-04-12 Banner Pharmacaps, Inc. Enteric valproic acid
US8748126B2 (en) 2005-11-29 2014-06-10 Actogenix N.V. Induction of mucosal tolerance to antigens
PL1962873T3 (pl) * 2005-12-14 2014-03-31 Oxthera Intellectual Property Ab Kompozycje farmaceutyczne zawierające bakterie zmniejszające ilość szczawianu
JP5558002B2 (ja) 2005-12-16 2014-07-23 オクセラ インコーポレイテッド シュウ酸塩低減化のための組成物および方法
US20070148248A1 (en) 2005-12-22 2007-06-28 Banner Pharmacaps, Inc. Gastric reflux resistant dosage forms
US20070154542A1 (en) * 2005-12-30 2007-07-05 Cogentus Pharmaceuticals, Inc. Oral pharmaceutical formulations containing non-steroidal anti-inflammatory drugs and acid inhibitors
SE529040C2 (sv) 2006-01-18 2007-04-17 Bows Pharmaceuticals Ag Förfarande för framställning av en dextranmatris för kontrollerad frisättning av insulin
US8048413B2 (en) 2006-05-17 2011-11-01 Helene Huguet Site-specific intestinal delivery of adsorbents, alone or in combination with degrading molecules
ES2895666T3 (es) 2006-10-27 2022-02-22 Capsugel Belgium Nv Cápsulas duras de hidroxipropilmetilcelulosa y proceso de fabricación
BRPI0807857A2 (pt) 2007-01-25 2014-05-27 Actogenix Nv Tratamento de doença imune por meio de distribuição através da mucosa de antígenos.
CN103120653B (zh) 2007-04-04 2015-09-30 希格默伊德药业有限公司 一种口服药物组合物
IT1393245B1 (it) * 2008-07-24 2012-04-12 Universita' Degli Studi Di Milano Forme farmaceutiche per il rilascio tempo-specifico di farmaci
US9757346B2 (en) 2008-09-03 2017-09-12 Volant Holdings Gmbh Compositions and methods for treating insulin resistance and non-insulin dependent diabetes mellitus (type II diabetes)
WO2010027498A2 (en) * 2008-09-03 2010-03-11 New Science Holdings, Llc Compositions and methods for inducing satiety and treating non-insulin dependent diabetes emillitus, pre-diabetic symptoms, insulin resistance and related disease states and conditions
AU2009290712A1 (en) 2008-09-09 2010-03-18 Astrazeneca Ab Method for delivering a pharmaceutical composition to patient in need thereof
KR101053731B1 (ko) * 2008-10-21 2011-08-02 이문성 용해시간 조절형 장세척제 조성물의 제조방법
DE102009001636A1 (de) * 2009-03-18 2010-09-23 Henkel Ag & Co. Kgaa Bleichmittel mit verzögertem Bleichbeginn
AU2010263304A1 (en) 2009-06-25 2012-02-02 Astrazeneca Ab Method for treating a patient at risk for developing an NSAID-associated ulcer
JP2012531430A (ja) * 2009-06-25 2012-12-10 ポーゼン インコーポレイテッド アスピリン療法を必要とする患者を治療するための方法
EP2283830A1 (de) 2009-07-23 2011-02-16 Actogenix N.V. Wässriger magensaftresistenter Kapselüberzug
KR101705204B1 (ko) 2009-09-11 2017-02-09 롯데정밀화학 주식회사 장용성 경질 캡슐용 수성 조성물, 장용성 경질 캡슐의 제조방법 및 장용성 경질 캡슐
NZ598783A (en) 2009-09-18 2013-07-26 Adolor Corp Use of opioid receptor antagonist for gastrointestinal tract disorders
KR101708086B1 (ko) 2010-02-25 2017-02-17 에보니크 룀 게엠베하 제약 또는 기능식품 제제
CN103153289B (zh) * 2010-08-25 2016-08-31 格兰特·鲁弗斯·斯柏林二世 改进型肠溶活性物质给药
EP3354335A1 (de) 2010-10-26 2018-08-01 Capsugel Belgium NV Bulk-enterale kapselhüllen
KR101747211B1 (ko) * 2010-11-19 2017-06-14 롯데정밀화학 주식회사 장용성 경질 캡슐용 조성물 및 상기 조성물을 사용하여 제조된 장용성 경질 캡슐
RU2766157C2 (ru) 2011-06-01 2022-02-08 Интрексон Актобиотикс Н.В. Система полицистронной экспрессии для бактерий
US10653631B2 (en) 2011-09-07 2020-05-19 Roland SAUR-BROSCH Optimal colon targeting technology
JP2014529630A (ja) 2011-09-07 2014-11-13 ザウラー−ブロシュ、ローラント 哺乳類の消化管における一つあるいは複数の物質の放出制御製剤
WO2013150331A1 (en) 2011-11-09 2013-10-10 Capsugel Belgium Nv Acid resistant banding solution for acid resistant two piece hard capsules
CA2860231A1 (en) 2011-12-28 2013-07-04 Pozen Inc. Improved compositions and methods for delivery of omeprazole plus acetylsalicylic acid
CN109172816A (zh) 2012-03-29 2019-01-11 塞拉拜姆有限责任公司 在回肠和阑尾上有活性的胃肠位点特异性口服接种疫苗制剂
CN103355656B (zh) * 2012-04-01 2016-01-20 中国科学院大连化学物理研究所 一种益生菌微胶囊产品及其制备与应用
US10525010B2 (en) 2012-05-02 2020-01-07 Capsugel Belgium Nv Aqueous dispersions of controlled release polymers and shells and capsules thereof
BR112014030160A2 (pt) * 2012-07-23 2017-06-27 Dow Global Technologies Llc composição formadora de película, uso de uma composição formadora de película, película e cápsula dura
US20140066837A1 (en) 2012-07-26 2014-03-06 Ronald L. Moy Skin care compositions and methods
KR20150046310A (ko) * 2012-08-29 2015-04-29 샐릭스 파마슈티컬스 인코포레이티드 완화제 조성물 및 변비 및 관련 위장관 질병 및 증상 치료를 위한 방법
US20140141075A1 (en) * 2012-11-21 2014-05-22 Warner Chilcott Company, Llc 5-aminosalicylic acid capsule formulation
WO2014120804A1 (en) * 2013-01-30 2014-08-07 University Of Miami Enteric coated nanoparticles for oral vaccine and drug delivery and methods of production and use thereof
RU2015140610A (ru) 2013-03-14 2017-04-17 ТЕРАБАЙОМ, ЭлЭлСи Направленная доставка в желудочно-кишечный тракт пробиотических микроорганизмов и/или терапевтических средств
WO2015065848A1 (en) 2013-11-04 2015-05-07 Capsugel Belgium Nv Methods and systems for improved bioavailability of active pharmaceutical ingredients including esomeprazole
ES2793530T3 (es) * 2014-05-19 2020-11-16 Tillotts Pharma Ag Cápsulas revestidas de liberación modificada
EP3028694B1 (de) 2014-12-02 2017-07-12 Capsugel Belgium NV Dosierformartikel für zeitverzögerte Freisetzung
EP3566699A1 (de) 2015-11-10 2019-11-13 Capsugel Belgium NV Säurebeständige bändelungs- oder dichtungslösung für säurebeständige zweiteilige hartkapseln
JP7292877B2 (ja) 2016-01-14 2023-06-19 イントレクソン・アクトバイオテイクス・エヌブイ 1型糖尿病を処置するための組成物および方法
JP2019529592A (ja) * 2016-08-23 2019-10-17 ダウ グローバル テクノロジーズ エルエルシー セルロースエーテルアセテートフタレート
WO2018042390A1 (en) 2016-09-02 2018-03-08 Intrexon Actobiotics N.V. Genetically modified bacteria stably expressing il-10 and insulin
CN109983028B (zh) 2016-09-13 2023-10-20 英特瑞克斯顿阿克图比奥帝克斯有限公司 黏膜黏附性微生物
US10561630B2 (en) 2016-10-25 2020-02-18 Glykon Technologies Group, Llc Hydroxycitric acid compounds and capsule liquid delivery
KR20200026901A (ko) 2017-07-11 2020-03-11 쿠오리카프스 가부시키가이샤 장용성 경질 캡슐
EP3787606A1 (de) * 2018-05-03 2021-03-10 M W Encap Limited Dosierformen zur verabreichung von medikamenten an den unteren magen-darm-trakt
WO2019245031A1 (ja) 2018-06-22 2019-12-26 クオリカプス株式会社 腸溶性硬質カプセル
EP3610862A1 (de) * 2018-08-14 2020-02-19 Apillet APS Neuartige orale zusammensetzung
CN109528689B (zh) * 2018-12-24 2021-09-21 江苏辰星药业股份有限公司 一种肠溶缓释植物胶囊及其制备方法
EP4034144A1 (de) 2019-09-27 2022-08-03 Intrexon Actobiotics NV d/b/a Precigen Actobio Behandlung von zöliakie
WO2022016398A1 (zh) * 2020-07-22 2022-01-27 绍兴康可胶囊有限公司 肠溶羟丙甲纤维素空心胶囊
CN113164405B (zh) * 2020-07-22 2022-09-06 绍兴康可胶囊有限公司 羟丙甲纤维素空心胶囊
WO2022137265A1 (en) * 2021-10-18 2022-06-30 Nutra Grace Enteric coated hpmc based herbal oil capsule for treatment of irritable bowel syndrome
WO2023212749A2 (en) * 2022-04-29 2023-11-02 Novatek Therapeutics, Llc Black seed oil formulations
KR20240086758A (ko) * 2022-11-30 2024-06-19 주식회사 마이크로바이오틱스 대변 미생물총 이식용 이중캡슐 및 이의 제조방법

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4138013A (en) 1976-08-27 1979-02-06 Parke, Davis & Company Enteric capsules
JPS61100519A (ja) * 1984-10-23 1986-05-19 Shin Etsu Chem Co Ltd 医薬用硬質カプセル
US5314696A (en) * 1991-06-27 1994-05-24 Paulos Manley A Methods for making and administering a blinded oral dosage form and blinded oral dosage form therefor
JP3116602B2 (ja) * 1992-10-06 2000-12-11 シオノギクオリカプス株式会社 硬質カプセル
US5656290A (en) * 1993-02-26 1997-08-12 The Procter & Gamble Company Bisacodyl dosage form with multiple enteric polymer coatings for colonic delivery
DE4329503A1 (de) * 1993-09-01 1995-03-02 Galenik Labor Freiburg Gmbh Pharmazeutische Präparate zur gezielten Behandlung von Morbus Crohn und Colitis Ulcerosa
GB9412394D0 (en) * 1994-06-21 1994-08-10 Danbiosyst Uk Colonic drug delivery composition
DE9414065U1 (de) * 1994-08-31 1994-11-03 Röhm GmbH & Co. KG, 64293 Darmstadt Thermoplastischer Kunststoff für darmsaftlösliche Arznei-Umhüllungen
JP2959423B2 (ja) * 1994-12-01 1999-10-06 シオノギクオリカプス株式会社 カプセル用皮膜組成物
SG80553A1 (en) * 1995-07-20 2001-05-22 Tanabe Seiyaku Co Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract
JP3185206B2 (ja) * 1995-07-20 2001-07-09 田辺製薬株式会社 消化管下部放出型被覆カプセル製剤
EP0919228A4 (de) * 1996-08-02 2001-12-12 Hisamitsu Pharmaceutical Co Kapseln für orale zubereitungen und kapselzubereitungen zur oralen verabreichung
JPH10152431A (ja) * 1996-08-02 1998-06-09 Hisamitsu Pharmaceut Co Inc 経口製剤用カプセルと経口カプセル製剤

Also Published As

Publication number Publication date
KR20010075395A (ko) 2001-08-09
CA2344680C (en) 2008-11-25
US20010036473A1 (en) 2001-11-01
WO2000018377A1 (en) 2000-04-06
CA2344680A1 (en) 2000-04-06
JP2002525314A (ja) 2002-08-13
DE69922394T2 (de) 2005-12-22
EP1117386A1 (de) 2001-07-25
ID28275A (id) 2001-05-10
KR100695562B1 (ko) 2007-03-15
US7094425B2 (en) 2006-08-22
CN100358509C (zh) 2008-01-02
PT1117386E (pt) 2005-04-29
DE69922394D1 (de) 2005-01-05
MXPA01003197A (es) 2004-04-21
ES2234306T3 (es) 2005-06-16
AU757343B2 (en) 2003-02-20
EP1117386B1 (de) 2004-12-01
AU6261399A (en) 2000-04-17
CN1321085A (zh) 2001-11-07
JP5068401B2 (ja) 2012-11-07

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