ATE277931T1 - Bicyclische stickstoffheteroaryl verbindungen - Google Patents
Bicyclische stickstoffheteroaryl verbindungenInfo
- Publication number
- ATE277931T1 ATE277931T1 AT99953796T AT99953796T ATE277931T1 AT E277931 T1 ATE277931 T1 AT E277931T1 AT 99953796 T AT99953796 T AT 99953796T AT 99953796 T AT99953796 T AT 99953796T AT E277931 T1 ATE277931 T1 AT E277931T1
- Authority
- AT
- Austria
- Prior art keywords
- lower alkyl
- heteroaryl
- aryl
- cycloalkyl
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Inorganic Insulating Materials (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9823277.0A GB9823277D0 (en) | 1998-10-23 | 1998-10-23 | Bicycle nitrogen heterocycles |
GBGB9920044.6A GB9920044D0 (en) | 1998-10-23 | 1999-08-24 | Biciclic nitrogen heterocycles |
PCT/EP1999/007675 WO2000024744A1 (en) | 1998-10-23 | 1999-10-13 | Bicyclic nitrogen heterocycles |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE277931T1 true ATE277931T1 (de) | 2004-10-15 |
Family
ID=26314565
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99953796T ATE277931T1 (de) | 1998-10-23 | 1999-10-13 | Bicyclische stickstoffheteroaryl verbindungen |
Country Status (25)
Country | Link |
---|---|
US (1) | US6150373A (de) |
EP (1) | EP1123295B1 (de) |
JP (1) | JP3593035B2 (de) |
CN (1) | CN1150195C (de) |
AT (1) | ATE277931T1 (de) |
AU (1) | AU769989B2 (de) |
BR (1) | BR9914677A (de) |
CA (1) | CA2347474C (de) |
CZ (1) | CZ20011394A3 (de) |
DE (1) | DE69920732T2 (de) |
ES (1) | ES2228123T3 (de) |
HK (1) | HK1041483B (de) |
HR (1) | HRP20010274A2 (de) |
HU (1) | HUP0104199A3 (de) |
ID (1) | ID28276A (de) |
MA (1) | MA27678A1 (de) |
MY (1) | MY126478A (de) |
NO (1) | NO318802B1 (de) |
NZ (1) | NZ510760A (de) |
PL (1) | PL347432A1 (de) |
PT (1) | PT1123295E (de) |
RU (1) | RU2256662C2 (de) |
TR (1) | TR200101102T2 (de) |
TW (1) | TWI227235B (de) |
WO (1) | WO2000024744A1 (de) |
Families Citing this family (73)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW517055B (en) * | 1997-07-02 | 2003-01-11 | Smithkline Beecham Corp | Novel substituted imidazole compounds |
JP2001526230A (ja) | 1997-12-19 | 2001-12-18 | スミスクライン・ビーチャム・コーポレイション | ヘテロアリール置換イミダゾール化合物、その医薬組成物および使用 |
ES2310039T3 (es) | 1998-05-26 | 2008-12-16 | Warner-Lambert Company Llc | Pirimidinas biciclicas y 3,4-dihidropirimidinas biciclicas como inhibidores de la proliferacion celular. |
US6858617B2 (en) | 1998-05-26 | 2005-02-22 | Smithkline Beecham Corporation | Substituted imidazole compounds |
US20040044012A1 (en) * | 1998-05-26 | 2004-03-04 | Dobrusin Ellen Myra | Bicyclic pyrimidines and bicyclic 3,4-dihydropyrimidines as inhibitors of cellular proliferation |
US6599910B1 (en) | 1998-08-20 | 2003-07-29 | Smithkline Beecham Corporation | Substituted triazole compounds |
ES2212657T3 (es) | 1998-11-04 | 2004-07-16 | Smithkline Beecham Corporation | Pirazinas sustituidas piridin-4-il o pirimidin-4-il. |
JP3961830B2 (ja) * | 1999-10-21 | 2007-08-22 | エフ.ホフマン−ラ ロシュ アーゲー | p38プロテインキナーゼのインヒビターとしてのヘテロアルキルアミノ置換二環式窒素複素環 |
MXPA02003841A (es) | 1999-10-21 | 2002-09-30 | Hoffmann La Roche | Heterociclos de nitrogeno biciclicos alquilamino substituidos como inhibidores de proteina p38. |
JP2003514900A (ja) | 1999-11-23 | 2003-04-22 | スミスクライン・ビーチャム・コーポレイション | CSBP/p38キナーゼ阻害剤としての3,4−ジヒドロ−(1H)−キナゾリン−2−オン化合物 |
ATE305787T1 (de) | 1999-11-23 | 2005-10-15 | Smithkline Beecham Corp | 3,4-dihydro-(1h)chinazolin-2-on-verbindungen als csbp/p39-kinase-inhibitoren |
ES2230171T3 (es) | 1999-11-23 | 2005-05-01 | Smithkline Beecham Corporation | Compuestos 3,4-dihidro-(1h)quinazolin-2-ona como inhibidores de csbp/p38 quinasa. |
US6759410B1 (en) * | 1999-11-23 | 2004-07-06 | Smithline Beecham Corporation | 3,4-dihydro-(1H)-quinazolin-2-ones and their use as CSBP/p38 kinase inhibitors |
US7101869B2 (en) | 1999-11-30 | 2006-09-05 | Pfizer Inc. | 2,4-diaminopyrimidine compounds useful as immunosuppressants |
MY141144A (en) * | 2000-03-02 | 2010-03-15 | Smithkline Beecham Corp | 1, 5-disubstituted-3,4-dihydro-1h-pyrimido 4,5-dipyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases |
US7235551B2 (en) * | 2000-03-02 | 2007-06-26 | Smithkline Beecham Corporation | 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases |
CZ20031125A3 (cs) | 2000-10-23 | 2003-10-15 | Smithkline Beecham Corporation | Nové sloučeniny |
DK1368028T3 (da) | 2001-03-12 | 2007-12-27 | Avanir Pharmaceuticals | Benzimidazolforbindelser til IgE-modulering og inhibering af cellulær profi-ferering |
US7119111B2 (en) | 2002-05-29 | 2006-10-10 | Amgen, Inc. | 2-oxo-1,3,4-trihydroquinazolinyl derivatives and methods of use |
US7196090B2 (en) * | 2002-07-25 | 2007-03-27 | Warner-Lambert Company | Kinase inhibitors |
DE10235312A1 (de) * | 2002-08-01 | 2004-02-12 | Basf Ag | Verfahren zur Herstellung von Aminoalkoxybenzylaminen und Aminoalkoxybenzonitrilen als Zwischenprodukte |
US7084270B2 (en) * | 2002-08-14 | 2006-08-01 | Hoffman-La Roche Inc. | Pyrimido compounds having antiproliferative activity |
WO2004024655A2 (en) | 2002-09-12 | 2004-03-25 | Avanir Pharmaceuticals | Phenyl-indole compounds for modulating ige and inhibiting cellular proliferation |
TW200413381A (en) | 2002-11-04 | 2004-08-01 | Hoffmann La Roche | Novel amino-substituted dihydropyrimido [4,5-d]pyrimidinone derivatives, their manufacture and use as pharmaceutical agents |
US7129351B2 (en) | 2002-11-04 | 2006-10-31 | Hoffmann-La Roche Inc. | Pyrimido compounds having antiproliferative activity |
US7098332B2 (en) | 2002-12-20 | 2006-08-29 | Hoffmann-La Roche Inc. | 5,8-Dihydro-6H-pyrido[2,3-d]pyrimidin-7-ones |
BRPI0409366A (pt) | 2003-04-10 | 2006-04-25 | Hoffmann La Roche | compostos de pirimido |
EP2308828A3 (de) * | 2003-04-23 | 2013-05-22 | Japan Tobacco Inc. | CaSR-Antagonist |
CA2533774A1 (en) * | 2003-07-29 | 2005-02-10 | Irm Llc | Compounds and compositions as protein kinase inhibitors |
WO2006115509A2 (en) | 2004-06-24 | 2006-11-02 | Novartis Vaccines And Diagnostics Inc. | Small molecule immunopotentiators and assays for their detection |
CA2576818A1 (en) * | 2004-08-31 | 2006-03-09 | F. Hoffmann-La Roche Ag | Amide derivatives of 3-phenyl dihydropyrimido[4,5-d]pyrimidinones, their manufacture and use as pharmaceutical agents |
EP1789417A1 (de) * | 2004-08-31 | 2007-05-30 | F.Hoffmann-La Roche Ag | Amid-derivate von 7-amino-3-phenyl-dihydropyrimido[4,5-d]pyrimidinone, verfahren zu ihrer herstellung und ihre verwendung als proteinkinasehemmer |
TWI389690B (zh) | 2005-03-25 | 2013-03-21 | Glaxo Group Ltd | 新穎化合物(一) |
DE602007001952D1 (de) | 2006-01-31 | 2009-09-24 | Hoffmann La Roche | 7h-pyridoä3,4-düpyrimidin-8-one, ihre herstellung und ihre verwendung als proteinkinaseinhibitoren |
US7897762B2 (en) * | 2006-09-14 | 2011-03-01 | Deciphera Pharmaceuticals, Llc | Kinase inhibitors useful for the treatment of proliferative diseases |
US8754114B2 (en) | 2010-12-22 | 2014-06-17 | Incyte Corporation | Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3 |
CN102816162B (zh) * | 2011-06-10 | 2016-04-27 | 中国科学院广州生物医药与健康研究院 | 嘧啶并嘧啶酮类化合物及其药用组合物和应用 |
GB201204384D0 (en) | 2012-03-13 | 2012-04-25 | Univ Dundee | Anti-flammatory agents |
UA117347C2 (uk) | 2012-06-13 | 2018-07-25 | Інсайт Холдинґс Корпорейшн | Заміщені трициклічні сполуки як інгібітори fgfr |
WO2014026125A1 (en) | 2012-08-10 | 2014-02-13 | Incyte Corporation | Pyrazine derivatives as fgfr inhibitors |
US9266892B2 (en) | 2012-12-19 | 2016-02-23 | Incyte Holdings Corporation | Fused pyrazoles as FGFR inhibitors |
AR095464A1 (es) | 2013-03-15 | 2015-10-21 | Celgene Avilomics Res Inc | Compuestos de heteroarilo y usos de los mismos |
EP3943087A1 (de) | 2013-03-15 | 2022-01-26 | Celgene CAR LLC | Heteroarylverbindungen und verwendungen davon |
CN105307657B (zh) | 2013-03-15 | 2020-07-10 | 西建卡尔有限责任公司 | 杂芳基化合物和其用途 |
CN105263931B (zh) | 2013-04-19 | 2019-01-25 | 因赛特公司 | 作为fgfr抑制剂的双环杂环 |
CA2954186A1 (en) | 2014-07-21 | 2016-01-28 | Dana-Farber Cancer Institute, Inc. | Imidazolyl kinase inhibitors and uses thereof |
CA2954187C (en) | 2014-07-21 | 2022-08-16 | Dana-Farber Cancer Institute, Inc. | Macrocyclic kinase inhibitors and uses thereof |
AU2015300782B2 (en) | 2014-08-08 | 2020-04-16 | Dana-Farber Cancer Institute, Inc. | Uses of salt-inducible kinase (SIK) inhibitors |
US10851105B2 (en) | 2014-10-22 | 2020-12-01 | Incyte Corporation | Bicyclic heterocycles as FGFR4 inhibitors |
UA121669C2 (uk) | 2015-02-20 | 2020-07-10 | Інсайт Корпорейшн | Біциклічні гетероцикли як інгібітори fgfr |
WO2016134294A1 (en) | 2015-02-20 | 2016-08-25 | Incyte Corporation | Bicyclic heterocycles as fgfr4 inhibitors |
MA41551A (fr) | 2015-02-20 | 2017-12-26 | Incyte Corp | Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4 |
WO2017031116A1 (en) * | 2015-08-18 | 2017-02-23 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Small molecule inhibitors of ku70/80 and uses thereof |
EP4047001A3 (de) * | 2016-07-05 | 2022-11-30 | The Broad Institute, Inc. | Bicyclische harnstoffkinaseinhibitoren und verwendungen davon |
US11241435B2 (en) | 2016-09-16 | 2022-02-08 | The General Hospital Corporation | Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis |
JP7296318B2 (ja) | 2017-02-28 | 2023-06-22 | ザ ジェネラル ホスピタル コーポレイション | Sikインヒビターとしてのピリミドピリミジノンの使用 |
AR111960A1 (es) | 2017-05-26 | 2019-09-04 | Incyte Corp | Formas cristalinas de un inhibidor de fgfr y procesos para su preparación |
US11685729B2 (en) | 2018-01-19 | 2023-06-27 | Idorsia Pharmaceuticals Ltd. | C5a receptor modulators |
WO2019141803A1 (en) | 2018-01-19 | 2019-07-25 | Idorsia Pharmaceuticals Ltd | C5a receptor modulators |
SG11202010636VA (en) | 2018-05-04 | 2020-11-27 | Incyte Corp | Solid forms of an fgfr inhibitor and processes for preparing the same |
MA52493A (fr) | 2018-05-04 | 2021-03-10 | Incyte Corp | Sels d'un inhibiteur de fgfr |
MX2021007833A (es) * | 2018-12-27 | 2021-10-26 | Les Laboratoires Servier Sas | Inhibidores aza-heterobiciclicos de mat2a y metodos de uso en el tratamiento de cancer. |
AU2019413683A1 (en) * | 2018-12-28 | 2021-08-12 | Spv Therapeutics Inc | Cyclin-dependent kinase inhibitors |
US11628162B2 (en) | 2019-03-08 | 2023-04-18 | Incyte Corporation | Methods of treating cancer with an FGFR inhibitor |
WO2021007269A1 (en) | 2019-07-09 | 2021-01-14 | Incyte Corporation | Bicyclic heterocycles as fgfr inhibitors |
WO2021011778A1 (en) * | 2019-07-16 | 2021-01-21 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Small molecule inhibitors of ku70/80 and uses thereof |
PE20221085A1 (es) | 2019-10-14 | 2022-07-05 | Incyte Corp | Heterociclos biciclicos como inhibidores de fgfr |
WO2021076728A1 (en) | 2019-10-16 | 2021-04-22 | Incyte Corporation | Bicyclic heterocycles as fgfr inhibitors |
GB201915828D0 (en) * | 2019-10-31 | 2019-12-18 | Cancer Research Tech Ltd | Compounds, compositions and therapeutic uses thereof |
WO2021113479A1 (en) | 2019-12-04 | 2021-06-10 | Incyte Corporation | Tricyclic heterocycles as fgfr inhibitors |
CN115151539A (zh) | 2019-12-04 | 2022-10-04 | 因赛特公司 | Fgfr抑制剂的衍生物 |
US20230192701A1 (en) * | 2020-04-28 | 2023-06-22 | Iomx Therapeutics Ag | Bicyclic kinase inhibitors and uses thereof |
CA3220274A1 (en) | 2021-06-09 | 2022-12-15 | Incyte Corporation | Tricyclic heterocycles as fgfr inhibitors |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5679683A (en) * | 1994-01-25 | 1997-10-21 | Warner-Lambert Company | Tricyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family |
IL117923A (en) * | 1995-05-03 | 2000-06-01 | Warner Lambert Co | Anti-cancer pharmaceutical compositions containing polysubstituted pyrido¬2,3-d¾pyrimidine derivatives and certain such novel compounds |
GB9619284D0 (en) * | 1996-09-16 | 1996-10-30 | Celltech Therapeutics Ltd | Chemical compounds |
EP0946523A1 (de) * | 1996-12-23 | 1999-10-06 | Celltech Therapeutics Limited | Kondensierte polycyclische 2-aminopyrimidinderivate, ihre herstellung und verwendung als proteininhibitoren von tyrosinkinase |
ES2310039T3 (es) * | 1998-05-26 | 2008-12-16 | Warner-Lambert Company Llc | Pirimidinas biciclicas y 3,4-dihidropirimidinas biciclicas como inhibidores de la proliferacion celular. |
-
1999
- 1999-10-13 ID IDW20010903A patent/ID28276A/id unknown
- 1999-10-13 DE DE69920732T patent/DE69920732T2/de not_active Expired - Fee Related
- 1999-10-13 PT PT99953796T patent/PT1123295E/pt unknown
- 1999-10-13 HU HU0104199A patent/HUP0104199A3/hu unknown
- 1999-10-13 PL PL99347432A patent/PL347432A1/xx not_active Application Discontinuation
- 1999-10-13 NZ NZ510760A patent/NZ510760A/en unknown
- 1999-10-13 WO PCT/EP1999/007675 patent/WO2000024744A1/en active IP Right Grant
- 1999-10-13 CZ CZ20011394A patent/CZ20011394A3/cs unknown
- 1999-10-13 TR TR2001/01102T patent/TR200101102T2/xx unknown
- 1999-10-13 EP EP99953796A patent/EP1123295B1/de not_active Expired - Lifetime
- 1999-10-13 AT AT99953796T patent/ATE277931T1/de not_active IP Right Cessation
- 1999-10-13 AU AU10363/00A patent/AU769989B2/en not_active Ceased
- 1999-10-13 ES ES99953796T patent/ES2228123T3/es not_active Expired - Lifetime
- 1999-10-13 CA CA002347474A patent/CA2347474C/en not_active Expired - Fee Related
- 1999-10-13 CN CNB998124702A patent/CN1150195C/zh not_active Expired - Fee Related
- 1999-10-13 JP JP2000578314A patent/JP3593035B2/ja not_active Expired - Fee Related
- 1999-10-13 RU RU2001113444/04A patent/RU2256662C2/ru not_active IP Right Cessation
- 1999-10-13 BR BR9914677-0A patent/BR9914677A/pt not_active IP Right Cessation
- 1999-10-21 US US09/422,451 patent/US6150373A/en not_active Expired - Fee Related
- 1999-10-21 MY MYPI99004545A patent/MY126478A/en unknown
- 1999-11-03 TW TW088119157A patent/TWI227235B/zh active
-
2001
- 2001-04-12 HR HR20010274A patent/HRP20010274A2/hr not_active Application Discontinuation
- 2001-04-19 NO NO20011929A patent/NO318802B1/no unknown
- 2001-04-20 MA MA26172A patent/MA27678A1/fr unknown
-
2002
- 2002-04-24 HK HK02103084.9A patent/HK1041483B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
BR9914677A (pt) | 2001-07-17 |
AU1036300A (en) | 2000-05-15 |
MY126478A (en) | 2006-10-31 |
MA27678A1 (fr) | 2006-01-02 |
TR200101102T2 (tr) | 2002-01-21 |
HK1041483B (zh) | 2004-12-24 |
PL347432A1 (en) | 2002-04-08 |
AU769989B2 (en) | 2004-02-12 |
EP1123295B1 (de) | 2004-09-29 |
NO20011929D0 (no) | 2001-04-19 |
DE69920732D1 (de) | 2004-11-04 |
NO318802B1 (no) | 2005-05-09 |
TWI227235B (en) | 2005-02-01 |
CN1324360A (zh) | 2001-11-28 |
HUP0104199A3 (en) | 2002-12-28 |
JP3593035B2 (ja) | 2004-11-24 |
HUP0104199A2 (hu) | 2002-04-29 |
JP2002528455A (ja) | 2002-09-03 |
CA2347474C (en) | 2008-08-26 |
DE69920732T2 (de) | 2006-02-23 |
NZ510760A (en) | 2003-08-29 |
ES2228123T3 (es) | 2005-04-01 |
ID28276A (id) | 2001-05-10 |
PT1123295E (pt) | 2005-01-31 |
HRP20010274A2 (en) | 2002-06-30 |
RU2256662C2 (ru) | 2005-07-20 |
CZ20011394A3 (cs) | 2001-12-12 |
CA2347474A1 (en) | 2000-05-04 |
EP1123295A1 (de) | 2001-08-16 |
HK1041483A1 (en) | 2002-07-12 |
NO20011929L (no) | 2001-04-19 |
WO2000024744A1 (en) | 2000-05-04 |
CN1150195C (zh) | 2004-05-19 |
US6150373A (en) | 2000-11-21 |
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