ATE276250T1 - Benzo(5,6)cyclohepta(1,2-b)pyridin derivate anwendbar als farnesyl protein tranferase inhibitoren - Google Patents
Benzo(5,6)cyclohepta(1,2-b)pyridin derivate anwendbar als farnesyl protein tranferase inhibitorenInfo
- Publication number
- ATE276250T1 ATE276250T1 AT98932714T AT98932714T ATE276250T1 AT E276250 T1 ATE276250 T1 AT E276250T1 AT 98932714 T AT98932714 T AT 98932714T AT 98932714 T AT98932714 T AT 98932714T AT E276250 T1 ATE276250 T1 AT E276250T1
- Authority
- AT
- Austria
- Prior art keywords
- protein transferase
- cyclohepta
- benzo
- farnesyl protein
- pyridine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87749897A | 1997-06-17 | 1997-06-17 | |
| PCT/US1998/011409 WO1998057968A1 (en) | 1997-06-17 | 1998-06-15 | Benzo(5,6)cyclohepta(1,2-b)pyridine derivatives useful for inhibition of farnesyl protein transferase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE276250T1 true ATE276250T1 (de) | 2004-10-15 |
Family
ID=25370103
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98932714T ATE276250T1 (de) | 1997-06-17 | 1998-06-15 | Benzo(5,6)cyclohepta(1,2-b)pyridin derivate anwendbar als farnesyl protein tranferase inhibitoren |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1019398B1 (de) |
| JP (1) | JP2002504142A (de) |
| KR (1) | KR20010013944A (de) |
| CN (1) | CN1267300A (de) |
| AT (1) | ATE276250T1 (de) |
| AU (1) | AU8253298A (de) |
| CA (1) | CA2293368C (de) |
| DE (1) | DE69826301T2 (de) |
| ES (1) | ES2224413T3 (de) |
| HU (1) | HUP0003048A2 (de) |
| IL (1) | IL133392A0 (de) |
| NZ (1) | NZ501612A (de) |
| WO (1) | WO1998057968A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6979686B1 (en) | 2001-12-07 | 2005-12-27 | Pharmacia Corporation | Substituted pyrazoles as p38 kinase inhibitors |
| EP3741745B1 (de) * | 2018-01-19 | 2023-04-26 | Yuki Gosei Kogyo Co., Ltd. | Verfahren zur herstellung eines n-alkoxycarbonylpiperidinderivats und zwischenprodukt dafür |
| UY39661A (es) | 2021-03-09 | 2022-10-31 | Fmc Corp | Amidas bicíclicas para controlar plagas de invertebrados |
| WO2024170339A1 (en) | 2023-02-13 | 2024-08-22 | Syngenta Crop Protection Ag | Pesticidally active bicyclic compounds |
| WO2023097341A2 (en) | 2023-03-20 | 2023-06-01 | Fmc Corporation | Bicyclic amides and esters for controlling invertebrate pests |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4826853A (en) * | 1986-10-31 | 1989-05-02 | Schering Corporation | 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use |
| US5719148A (en) * | 1993-10-15 | 1998-02-17 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| IL111235A (en) * | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them |
| KR20000036111A (ko) * | 1996-09-13 | 2000-06-26 | 둘락 노먼 씨. | 파네실 단백질 트랜스페라제 억제제인 트리사이클릭 항종양성화합물 |
-
1998
- 1998-06-15 JP JP50448499A patent/JP2002504142A/ja not_active Ceased
- 1998-06-15 IL IL13339298A patent/IL133392A0/xx unknown
- 1998-06-15 CN CN98808200A patent/CN1267300A/zh active Pending
- 1998-06-15 DE DE69826301T patent/DE69826301T2/de not_active Expired - Lifetime
- 1998-06-15 NZ NZ501612A patent/NZ501612A/en unknown
- 1998-06-15 ES ES98932714T patent/ES2224413T3/es not_active Expired - Lifetime
- 1998-06-15 KR KR1019997011969A patent/KR20010013944A/ko not_active Application Discontinuation
- 1998-06-15 EP EP98932714A patent/EP1019398B1/de not_active Expired - Lifetime
- 1998-06-15 HU HU0003048A patent/HUP0003048A2/hu unknown
- 1998-06-15 WO PCT/US1998/011409 patent/WO1998057968A1/en active IP Right Grant
- 1998-06-15 AU AU82532/98A patent/AU8253298A/en not_active Abandoned
- 1998-06-15 AT AT98932714T patent/ATE276250T1/de not_active IP Right Cessation
- 1998-06-15 CA CA002293368A patent/CA2293368C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0003048A2 (hu) | 2001-06-28 |
| WO1998057968A1 (en) | 1998-12-23 |
| EP1019398B1 (de) | 2004-09-15 |
| EP1019398A1 (de) | 2000-07-19 |
| ES2224413T3 (es) | 2005-03-01 |
| DE69826301T2 (de) | 2005-10-13 |
| NZ501612A (en) | 2001-11-30 |
| KR20010013944A (ko) | 2001-02-26 |
| CA2293368C (en) | 2009-01-20 |
| IL133392A0 (en) | 2001-04-30 |
| CN1267300A (zh) | 2000-09-20 |
| JP2002504142A (ja) | 2002-02-05 |
| CA2293368A1 (en) | 1998-12-23 |
| DE69826301D1 (de) | 2004-10-21 |
| AU8253298A (en) | 1999-01-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |