ATE218137T1 - Benzo(5,6)cyclohepta(1,2-b)pyridin derivate als farnesyl protein transferase inhibitoren - Google Patents
Benzo(5,6)cyclohepta(1,2-b)pyridin derivate als farnesyl protein transferase inhibitorenInfo
- Publication number
- ATE218137T1 ATE218137T1 AT98930063T AT98930063T ATE218137T1 AT E218137 T1 ATE218137 T1 AT E218137T1 AT 98930063 T AT98930063 T AT 98930063T AT 98930063 T AT98930063 T AT 98930063T AT E218137 T1 ATE218137 T1 AT E218137T1
- Authority
- AT
- Austria
- Prior art keywords
- protein transferase
- farnesyl protein
- cyclohepta
- benzo
- pyridine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87650797A | 1997-06-17 | 1997-06-17 | |
| PCT/US1998/011499 WO1998057945A1 (en) | 1997-06-17 | 1998-06-15 | Benzo(5,6)cyclohepta(1,2-b)pyridine derivatives as farnesyl protein transferase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE218137T1 true ATE218137T1 (de) | 2002-06-15 |
Family
ID=25367883
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98930063T ATE218137T1 (de) | 1997-06-17 | 1998-06-15 | Benzo(5,6)cyclohepta(1,2-b)pyridin derivate als farnesyl protein transferase inhibitoren |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0991637B1 (de) |
| JP (1) | JP2002510308A (de) |
| KR (1) | KR20010013829A (de) |
| CN (1) | CN1272844A (de) |
| AT (1) | ATE218137T1 (de) |
| AU (1) | AU7953798A (de) |
| CA (1) | CA2293433C (de) |
| DE (1) | DE69805619T2 (de) |
| ES (1) | ES2174450T3 (de) |
| HK (1) | HK1024910A1 (de) |
| HU (1) | HUP0002659A3 (de) |
| IL (1) | IL133448A0 (de) |
| WO (1) | WO1998057945A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002211427A1 (en) * | 2000-10-05 | 2002-04-15 | Whitehead Institute For Biomedical Research | Effects of combined administration of farnesyl transferase inhibitors and signal transduction inhibitors |
| HUP0302913A3 (en) | 2000-10-05 | 2005-05-30 | Daley George Q Weston | Methods of inducing cancer cell death and tumor regression and preparation of pharmaceutical compositions suitable for treating the same |
| TW200418825A (en) | 2002-12-16 | 2004-10-01 | Hoffmann La Roche | Novel (R)-and (S) enantiomers of thiophene hydroxamic acid derivatives |
| KR20240035513A (ko) | 2021-07-09 | 2024-03-15 | 알리고스 테라퓨틱스 인코포레이티드 | 항바이러스 화합물 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4826853A (en) * | 1986-10-31 | 1989-05-02 | Schering Corporation | 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use |
| JPH0676403B2 (ja) * | 1991-01-18 | 1994-09-28 | エスエス製薬株式会社 | 新規なベンゾ［５，６ シクロヘプタ［１，２−ｂ ピリジン誘導体及びこれを含有する抗アレルギー剤 |
| US5719148A (en) * | 1993-10-15 | 1998-02-17 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| IL111235A (en) * | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them |
-
1998
- 1998-06-15 IL IL13344898A patent/IL133448A0/xx unknown
- 1998-06-15 WO PCT/US1998/011499 patent/WO1998057945A1/en not_active Application Discontinuation
- 1998-06-15 JP JP50449499A patent/JP2002510308A/ja not_active Ceased
- 1998-06-15 EP EP98930063A patent/EP0991637B1/de not_active Expired - Lifetime
- 1998-06-15 AU AU79537/98A patent/AU7953798A/en not_active Abandoned
- 1998-06-15 KR KR1019997011849A patent/KR20010013829A/ko not_active Application Discontinuation
- 1998-06-15 HU HU0002659A patent/HUP0002659A3/hu unknown
- 1998-06-15 CA CA002293433A patent/CA2293433C/en not_active Expired - Fee Related
- 1998-06-15 CN CN98808206A patent/CN1272844A/zh active Pending
- 1998-06-15 ES ES98930063T patent/ES2174450T3/es not_active Expired - Lifetime
- 1998-06-15 DE DE69805619T patent/DE69805619T2/de not_active Expired - Lifetime
- 1998-06-15 AT AT98930063T patent/ATE218137T1/de not_active IP Right Cessation
-
2000
- 2000-04-13 HK HK00102234A patent/HK1024910A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2293433C (en) | 2009-09-29 |
| HUP0002659A2 (hu) | 2001-06-28 |
| DE69805619T2 (de) | 2002-11-07 |
| HK1024910A1 (en) | 2000-10-27 |
| EP0991637A1 (de) | 2000-04-12 |
| JP2002510308A (ja) | 2002-04-02 |
| EP0991637B1 (de) | 2002-05-29 |
| AU7953798A (en) | 1999-01-04 |
| ES2174450T3 (es) | 2002-11-01 |
| KR20010013829A (ko) | 2001-02-26 |
| CA2293433A1 (en) | 1998-12-23 |
| CN1272844A (zh) | 2000-11-08 |
| DE69805619D1 (en) | 2002-07-04 |
| HUP0002659A3 (en) | 2002-11-28 |
| WO1998057945A1 (en) | 1998-12-23 |
| IL133448A0 (en) | 2001-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |