ATE270677T1 - Neues glycosaminoglycan und dieses enthaltendes arzneimittel - Google Patents

Neues glycosaminoglycan und dieses enthaltendes arzneimittel

Info

Publication number
ATE270677T1
ATE270677T1 AT99933225T AT99933225T ATE270677T1 AT E270677 T1 ATE270677 T1 AT E270677T1 AT 99933225 T AT99933225 T AT 99933225T AT 99933225 T AT99933225 T AT 99933225T AT E270677 T1 ATE270677 T1 AT E270677T1
Authority
AT
Austria
Prior art keywords
glycosaminoglycan
disaccharide
uronic acid
residue
product containing
Prior art date
Application number
AT99933225T
Other languages
English (en)
Inventor
Yutaka Kariya
Ryo Takano
Kaeko Kamei
Saburo Hara
Junichi Onaya
Yusuke Hori
Original Assignee
Seikagaku Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Kogyo Co Ltd filed Critical Seikagaku Kogyo Co Ltd
Application granted granted Critical
Publication of ATE270677T1 publication Critical patent/ATE270677T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
AT99933225T 1998-07-31 1999-08-02 Neues glycosaminoglycan und dieses enthaltendes arzneimittel ATE270677T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP21705198 1998-07-31
JP24638798 1998-08-31
PCT/JP1999/004155 WO2000006608A1 (fr) 1998-07-31 1999-08-02 Nouveau glycosaminoglycan et compositions medicamenteuses le contenant

Publications (1)

Publication Number Publication Date
ATE270677T1 true ATE270677T1 (de) 2004-07-15

Family

ID=26521784

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99933225T ATE270677T1 (de) 1998-07-31 1999-08-02 Neues glycosaminoglycan und dieses enthaltendes arzneimittel

Country Status (10)

Country Link
US (1) US6492503B1 (de)
EP (1) EP1022289B1 (de)
JP (2) JP4575595B2 (de)
KR (1) KR20010030803A (de)
CN (1) CN1286699A (de)
AT (1) ATE270677T1 (de)
AU (1) AU4933099A (de)
CA (1) CA2305619C (de)
DE (1) DE69918523T2 (de)
WO (1) WO2000006608A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2814463B1 (fr) 2000-09-22 2002-11-15 Sanofi Synthelabo Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine
JP4828795B2 (ja) 2002-03-11 2011-11-30 モメンタ ファーマシューティカルズ インコーポレイテッド 硫酸化多糖類の分析
DE10214507A1 (de) * 2002-04-02 2003-10-16 Beiersdorf Ag Verwendung von Acarbose und deren Derivaten zur Behandlung und Prophylaxe degenerativer Hautzustände
US7629967B2 (en) 2003-02-14 2009-12-08 Next Holdings Limited Touch screen signal processing
US8456447B2 (en) 2003-02-14 2013-06-04 Next Holdings Limited Touch screen signal processing
US8508508B2 (en) 2003-02-14 2013-08-13 Next Holdings Limited Touch screen signal processing with single-point calibration
EP1635782A1 (de) * 2003-05-24 2006-03-22 JUVENA (International) AG Gewebekulturmedien als bestandteil von kosmetika
WO2005026214A1 (ja) 2003-09-12 2005-03-24 Seikagaku Corporation 多糖擬スポンジ
KR100577075B1 (ko) * 2004-06-16 2006-05-08 주식회사 티앤라이프시스템 칼슘염 및 인산염, 또는 인산칼슘염을 이용한 히아루론산정제방법
AU2005283282B2 (en) 2004-09-15 2011-05-19 Seikagaku Corporation Photoreactive polysaccharide, photocrosslinked polysaccharide products, the method of making them and medical materials therefrom
US7659260B2 (en) * 2005-01-14 2010-02-09 Eddie Francis Kadrmas Tamponade compositions and methods for retinal repair
US9139876B1 (en) 2007-05-03 2015-09-22 Momenta Pharmacueticals, Inc. Method of analyzing a preparation of a low molecular weight heparin
KR20100055516A (ko) 2007-08-30 2010-05-26 넥스트 홀딩스 인코포레이티드 개선된 조광을 가진 광학 터치 스크린
EP2281008B1 (de) 2008-04-04 2017-01-04 University of Utah Research Foundation Alkylierte und sulfatierte hyaluronsäure, verfahren zu ihrer herstellung und ihre verwendung
EP2526122B1 (de) * 2010-01-19 2020-06-10 Momenta Pharmaceuticals, Inc. Beurteilung von heparinzubereitungen
US9068957B2 (en) 2011-02-21 2015-06-30 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations
EP2688402B1 (de) 2011-03-23 2018-10-24 University of Utah Research Foundation Mittel zur behandlung bzw. prävention von harnwegsentzündungen
JP5263349B2 (ja) * 2011-08-08 2013-08-14 生化学工業株式会社 生理活性分子含有架橋ヘパリンゲル組成物
ME02994B (de) * 2011-12-19 2018-10-20 Dilafor Ab Nicht antikoagulative glykosaminoglykane mit sich wiederholender disaccharideinheit und ihre medizinische verwendung
WO2013095215A1 (en) * 2011-12-19 2013-06-27 Dilaforette Ab Low anticoagulant heparins
CN105408361B (zh) * 2013-05-16 2019-09-06 新加坡科技研究局 硫酸乙酰肝素
CN103698425B (zh) * 2013-12-12 2015-08-26 中国海洋大学 一种化学降解法获得及检测生物来源糖胺聚糖二糖的方法
CN105504097B (zh) * 2015-12-30 2018-07-03 深圳市海普瑞药业集团股份有限公司 一种硫酸化肝素寡糖及其制备方法和应用
WO2018053111A1 (en) 2016-09-15 2018-03-22 University Of Utah Research Foundation In situ gelling compositions for the treatment or prevention of inflammation and tissue damage
CN113388044B (zh) * 2020-03-11 2023-03-31 中国科学院昆明植物研究所 一种蜗牛糖胺聚糖化合物、其药学上可接受的盐、制备方法及应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS609043B2 (ja) * 1976-06-22 1985-03-07 生化学工業株式会社 脱硫酸化ムコ多糖体の製造法
CA2130295A1 (en) * 1993-08-26 1995-02-27 Richard A. Berg Ionically crosslinked glycosaminoglycan gels for soft tissue augmentation and drug delivery
AU2435795A (en) 1994-05-06 1995-11-29 Glycomed Incorporated O-desulfated heparin derivatives, methods of making and uses thereof
EP1371666B1 (de) * 1994-07-01 2007-08-15 Seikagaku Corporation Verwendung von desulfatiertem Heparin

Also Published As

Publication number Publication date
CA2305619C (en) 2008-05-20
DE69918523T2 (de) 2005-07-28
KR20010030803A (ko) 2001-04-16
EP1022289A4 (de) 2001-10-17
EP1022289A1 (de) 2000-07-26
JP2010235956A (ja) 2010-10-21
US6492503B1 (en) 2002-12-10
AU4933099A (en) 2000-02-21
CA2305619A1 (en) 2000-02-10
EP1022289B1 (de) 2004-07-07
CN1286699A (zh) 2001-03-07
JP4575595B2 (ja) 2010-11-04
JP5189137B2 (ja) 2013-04-24
DE69918523D1 (de) 2004-08-12
WO2000006608A1 (fr) 2000-02-10

Similar Documents

Publication Publication Date Title
ATE270677T1 (de) Neues glycosaminoglycan und dieses enthaltendes arzneimittel
Bhat et al. Occurrence of lipid A variants with 27-hydroxyoctacosanoic acid in lipopolysaccharides from members of the family Rhizobiaceae
ATE256137T1 (de) Keratansulfatoligosaccharid-fraktion und sie enthaltendes medikament
EP0864582A3 (de) Hypolipidemische 1,4-Benzothiazepin-1,1-dioxide
BR0313226A (pt) Uso de agentes de floculação para separar resìduo sólido em substratos de fermentação hidrolisados
MY124548A (en) Synthetic polysaccharides, preparation method therefor and pharmaceutical compositons containing same
DE3850795T2 (de) Polysaccharid und Verfahren zu seiner Herstellung.
TWI262945B (en) Liquid detergent composition
Hopwood et al. Diagnosis of Sanfilippo type A syndrome by estimation of sulfamidase activity using a radiolabelled tetrasaccharide substrate
DE69805757T2 (de) Polysaccharid, mikroorganismus und verfahren zu dessen herstellung, dieses enthaltende zusammensetzung und verwendung
ATE41785T1 (de) Membranoese polysaccharide, verwendbar insbesondere als arzneimittel und verfahren zu ihrer herstellung.
Gaidi et al. Two new biologically active triterpene saponins from Acanthophyllum squarrosum
BR9807759A (pt) Composto, e, processo para espessamento de um sistema aquoso
Avigad et al. Fructosides formed from sucrose by a Corynebacterium
Fransson et al. The copolymeric structure of pig skin dermatan sulphate. Characterization of d-glucuronic acid-containing oligosaccharides isolated after controlled degradation of oxydermatan sulphate
Kusumoto et al. Chemical synthesis of 1-dephospho derivative of Escherichia coli Re lipopolysaccharide
IL100955A0 (en) Polyhydroxycyclopentane derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
Nelson et al. Partial characterization of lipid A of intraperiplasmically grown Bdellovibrio bacteriovorus
FR2692908B1 (fr) Procédé de cofermentation du glucose et du xylose en éthanol par culture mixte de microorganismes.
Urai et al. A novel viscous extracellular polysaccharide containing fatty acids from Rhodococcus rhodochrous ATCC 53968
Zbiral et al. Elucidation of the topological parameters of N-acetylneuraminic acid and some analogues involved in their interaction with the N-acetylneuraminate lyase from Clostridium perfringens
JPS643116A (en) Plaster for patch
Dekker et al. Isolation of α-glucan and lipopolysaccharide fractions from Acetobacter xylinum
Murata et al. High-performance liquid chromatographic identification of disaccharides generated from heparan sulphate isomers using heparitinases
NO970422L (no) Fremgangsmåte for fremstilling av polyhydroksyfettsyreamidopplösninger av god fargekvalitet og anvendelse av disse

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties