ATE269160T1 - Miniaturisierte probenvorbereitungsvorrichtungen sowie systeme zur feststellung und behandlung von analyten - Google Patents
Miniaturisierte probenvorbereitungsvorrichtungen sowie systeme zur feststellung und behandlung von analytenInfo
- Publication number
- ATE269160T1 ATE269160T1 AT95940711T AT95940711T ATE269160T1 AT E269160 T1 ATE269160 T1 AT E269160T1 AT 95940711 T AT95940711 T AT 95940711T AT 95940711 T AT95940711 T AT 95940711T AT E269160 T1 ATE269160 T1 AT E269160T1
- Authority
- AT
- Austria
- Prior art keywords
- sample preparation
- analytes
- treating
- detecting
- systems
- Prior art date
Links
- 230000003321 amplification Effects 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 238000000159 protein binding assay Methods 0.000 abstract 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/18—Apparatus therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/02—Inorganic material
- B01D71/0213—Silicon
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/02—Inorganic material
- B01D71/0215—Silicon carbide; Silicon nitride; Silicon oxycarbide
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00819—Materials of construction
- B01J2219/00824—Ceramic
- B01J2219/00826—Quartz
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00819—Materials of construction
- B01J2219/00824—Ceramic
- B01J2219/00828—Silicon wafers or plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00819—Materials of construction
- B01J2219/00831—Glass
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00819—Materials of construction
- B01J2219/00833—Plastic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00873—Heat exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/0095—Control aspects
- B01J2219/00952—Sensing operations
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/087—Multiple sequential chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Water Supply & Treatment (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Clinical Laboratory Science (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/338,728 US5587128A (en) | 1992-05-01 | 1994-11-14 | Mesoscale polynucleotide amplification devices |
US08/338,369 US5726026A (en) | 1992-05-01 | 1994-11-14 | Mesoscale sample preparation device and systems for determination and processing of analytes |
US08/338,380 US5744366A (en) | 1992-05-01 | 1994-11-14 | Mesoscale devices and methods for analysis of motile cells |
PCT/US1995/014825 WO1996014934A1 (en) | 1994-11-14 | 1995-11-13 | Mesoscale sample preparation device and systems for determination and processing of analytes |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE269160T1 true ATE269160T1 (de) | 2004-07-15 |
Family
ID=27407263
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95940711T ATE269160T1 (de) | 1994-11-14 | 1995-11-13 | Miniaturisierte probenvorbereitungsvorrichtungen sowie systeme zur feststellung und behandlung von analyten |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0739240B1 (de) |
JP (1) | JP3220158B2 (de) |
CN (1) | CN1110369C (de) |
AT (1) | ATE269160T1 (de) |
AU (1) | AU704277B2 (de) |
CA (1) | CA2181190C (de) |
DE (1) | DE69533159T2 (de) |
WO (1) | WO1996014934A1 (de) |
Families Citing this family (92)
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DE69619400T2 (de) * | 1995-06-16 | 2002-09-26 | Univ Washington Seattle | Flacher mikrogefertigter querstromfilter für flüssigkeiten |
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US5942443A (en) * | 1996-06-28 | 1999-08-24 | Caliper Technologies Corporation | High throughput screening assay systems in microscale fluidic devices |
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DE19648695C2 (de) * | 1996-11-25 | 1999-07-22 | Abb Patent Gmbh | Vorrichtung zur automatischen und kontinuierlichen Analyse von Flüssigkeitsproben |
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US6632619B1 (en) | 1997-05-16 | 2003-10-14 | The Governors Of The University Of Alberta | Microfluidic system and methods of use |
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GB2516666B (en) * | 2013-07-29 | 2015-09-09 | Atlas Genetics Ltd | Fluidic cartridge for nucleic acid amplification and detection |
AU2014353050B2 (en) * | 2013-11-20 | 2019-10-03 | Brigham And Women's Hospital, Inc. | System and method for sperm sorting |
CN107429281B (zh) * | 2014-12-31 | 2022-05-27 | 维斯比医学公司 | 用于分子诊断测试的装置和方法 |
ES2797223T3 (es) * | 2015-08-05 | 2020-12-01 | Minnetronix Inc | Sistema de filtro de flujo tangencial para la filtración de materiales a partir de fluidos biológicos |
KR101726064B1 (ko) * | 2015-08-06 | 2017-04-13 | 한양대학교 산학협력단 | 진동자를 구비하는 미세입자 분리소자 |
EP3529348A1 (de) * | 2016-11-24 | 2019-08-28 | Sensirion AG | Mikroorganismustestsystem |
US11305282B2 (en) | 2017-03-29 | 2022-04-19 | Cornell University | Devices, processes, and systems for determination of nucleic acid sequence, expression, copy number, or methylation changes using combined nuclease, ligase, polymerase, and sequencing reactions |
US10502707B1 (en) * | 2018-05-31 | 2019-12-10 | Taiwan Semiconductor Manufacturing Co., Ltd. | Differential sensing with bioFET sensors |
US20220184621A1 (en) * | 2020-12-14 | 2022-06-16 | National Central University | Integrated microfluidic chip for cell imaging and biochemical detection and method using the same |
DE102021106654B3 (de) * | 2021-03-18 | 2022-07-14 | Universität zu Köln, Körperschaft des öffentlichen Rechts | Kartusche und Verfahren zur Durchführung einer Reaktion |
DE102022213554A1 (de) | 2022-12-13 | 2024-06-13 | Robert Bosch Gesellschaft mit beschränkter Haftung | Vorrichtung und Verfahren zum Splitten dreidimensionaler Agglomerate |
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4676274A (en) * | 1985-02-28 | 1987-06-30 | Brown James F | Capillary flow control |
US5100627A (en) * | 1989-11-30 | 1992-03-31 | The Regents Of The University Of California | Chamber for the optical manipulation of microscopic particles |
EP0637998B2 (de) * | 1992-05-01 | 2006-04-12 | Trustees Of The University Of Pennsylvania | Fluessigkeitsbehandlung in mikrofabrizierten analytischen vorrichtungen |
-
1995
- 1995-11-13 CN CN95192097.9A patent/CN1110369C/zh not_active Expired - Fee Related
- 1995-11-13 AT AT95940711T patent/ATE269160T1/de not_active IP Right Cessation
- 1995-11-13 WO PCT/US1995/014825 patent/WO1996014934A1/en active IP Right Grant
- 1995-11-13 CA CA002181190A patent/CA2181190C/en not_active Expired - Fee Related
- 1995-11-13 AU AU42369/96A patent/AU704277B2/en not_active Ceased
- 1995-11-13 JP JP51629696A patent/JP3220158B2/ja not_active Expired - Lifetime
- 1995-11-13 DE DE69533159T patent/DE69533159T2/de not_active Expired - Lifetime
- 1995-11-13 EP EP95940711A patent/EP0739240B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP3220158B2 (ja) | 2001-10-22 |
EP0739240B1 (de) | 2004-06-16 |
AU4236996A (en) | 1996-06-06 |
EP0739240A1 (de) | 1996-10-30 |
CA2181190C (en) | 2001-02-06 |
WO1996014934A1 (en) | 1996-05-23 |
DE69533159T2 (de) | 2005-07-21 |
AU704277B2 (en) | 1999-04-15 |
CA2181190A1 (en) | 1996-05-23 |
MX9602774A (es) | 1997-07-31 |
CN1110369C (zh) | 2003-06-04 |
DE69533159D1 (de) | 2004-07-22 |
CN1143917A (zh) | 1997-02-26 |
JPH09509498A (ja) | 1997-09-22 |
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