ATE269066T1 - Kombinationstherapie zur prophylaxe und/oder behandlung von gutartiger prostatischer hyperplasie - Google Patents
Kombinationstherapie zur prophylaxe und/oder behandlung von gutartiger prostatischer hyperplasieInfo
- Publication number
- ATE269066T1 ATE269066T1 AT99106510T AT99106510T ATE269066T1 AT E269066 T1 ATE269066 T1 AT E269066T1 AT 99106510 T AT99106510 T AT 99106510T AT 99106510 T AT99106510 T AT 99106510T AT E269066 T1 ATE269066 T1 AT E269066T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- benign prostatic
- prostatic hyperplasia
- prophylaxis
- combination therapy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37670089A | 1989-07-07 | 1989-07-07 | |
EP98104849A EP0857487A3 (de) | 1989-07-07 | 1990-07-05 | Kombinationspräparate zur Prophylaxe und/oder Behandlung benigner Prostatahyperplasie welche ein beta-hydroxysteroid-dehydrogenaseinhibitor und zumindest ein weiteres aktives Bestandteil enthalten |
EP90909598A EP0480950B1 (de) | 1989-07-07 | 1990-07-05 | Kombinationstherapie zur prophylaxe und/oder behandlung benigner prostatahyperplasie |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE269066T1 true ATE269066T1 (de) | 2004-07-15 |
Family
ID=23486098
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99106510T ATE269066T1 (de) | 1989-07-07 | 1990-07-05 | Kombinationstherapie zur prophylaxe und/oder behandlung von gutartiger prostatischer hyperplasie |
AT90909598T ATE177949T1 (de) | 1989-07-07 | 1990-07-05 | Kombinationstherapie zur prophylaxe und/oder behandlung benigner prostatahyperplasie |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT90909598T ATE177949T1 (de) | 1989-07-07 | 1990-07-05 | Kombinationstherapie zur prophylaxe und/oder behandlung benigner prostatahyperplasie |
Country Status (17)
Country | Link |
---|---|
US (1) | US5817649A (de) |
EP (3) | EP0857487A3 (de) |
JP (2) | JP3332377B2 (de) |
KR (1) | KR920703063A (de) |
AT (2) | ATE269066T1 (de) |
AU (2) | AU643445B2 (de) |
CA (1) | CA2062973C (de) |
DE (2) | DE69033020T2 (de) |
DK (2) | DK0943328T3 (de) |
ES (2) | ES2133270T3 (de) |
HU (1) | HU223662B1 (de) |
IE (2) | IE902459A1 (de) |
IL (1) | IL94990A (de) |
MY (1) | MY106484A (de) |
NZ (1) | NZ234414A (de) |
WO (1) | WO1991000731A1 (de) |
ZA (1) | ZA905312B (de) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5204337A (en) * | 1988-10-31 | 1993-04-20 | Endorecherche Inc. | Estrogen nucleus derivatives for use in inhibition of sex steroid activity |
DE69034035T2 (de) * | 1989-07-07 | 2004-01-22 | Endorecherche Inc., Ste-Foy | Methode zur behandlung androgenbedingter krankheiten |
IL101245A0 (en) * | 1991-03-20 | 1992-11-15 | Merck & Co Inc | Pharmaceutical compositions for the treatment of prostatic cancer |
WO1992018132A1 (en) * | 1991-04-17 | 1992-10-29 | Merck & Co., Inc. | Pharmaceutical combination for the treatment of benign prostatic hyperplasia comtaining a 5 alpha-reductase inhibitor |
US5175155A (en) * | 1991-10-07 | 1992-12-29 | Sterling Winthrop Inc. | Win 49596-finasteride method of use and compositions |
GB9506678D0 (en) * | 1995-03-31 | 1995-05-24 | Glaxo Inc | Substituted 6-azacholesten-3-ones |
US5780435A (en) | 1995-12-15 | 1998-07-14 | Praecis Pharmaceuticals Incorporated | Methods for treating prostate cancer with LHRH-R antagonists |
EP1321146A3 (de) * | 1998-03-11 | 2004-06-02 | Endorecherche Inc. | Typ 5 und Typ 3 17 Beta-Hydroxisteroid-Dehydrogenasehemmer und Verfahren zu ihrer Anwendung |
JP2002506077A (ja) | 1998-03-11 | 2002-02-26 | アンドルシェルシュ・インコーポレイテッド | タイプ5およびタイプ317β−ヒドロキシステロイドデヒドロゲナーゼのインヒビターおよびその使用法 |
DE19825591A1 (de) * | 1998-06-09 | 1999-12-23 | Jenapharm Gmbh | Pharmazeutische Kombinationen zum Ausgleich eines Testosteron-Defizits beim Mann mit gleichzeitigem Schutz der Prostata |
US6268377B1 (en) * | 1998-09-28 | 2001-07-31 | Merck & Co., Inc. | Method for treating androgen-related conditions |
EP1253966B1 (de) * | 1999-08-13 | 2011-04-27 | Curadis GmbH | Substanzen und mittel zur positiven beeinflussung von kollagen |
US6200573B1 (en) | 1999-12-03 | 2001-03-13 | Starcor Pharmaceuticals, Inc. | Method of medical management for lower urinary tract symptoms and benign prostatic hyperplasia |
US20040077605A1 (en) * | 2001-06-20 | 2004-04-22 | Salvati Mark E. | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function |
US7001911B2 (en) | 2000-06-28 | 2006-02-21 | Bristol-Myers Squibb Company | Fused cyclic modulators of nuclear hormone receptor function |
EP1299094A2 (de) | 2000-06-28 | 2003-04-09 | Bristol-Myers Squibb Company | Selektive androgenrezeptormodulatoren und methoden zu deren identifizierung, entwurf und verwendung |
EP1304334A4 (de) * | 2000-06-30 | 2009-06-17 | Chugai Pharmaceutical Co Ltd | Neuer antiandrogener wirkstoff |
EP1854798A3 (de) | 2000-09-19 | 2007-11-28 | Bristol-Myers Squibb Company | Kondensierte heterozyklische Succinimid-Verbindungen und Analoga daraus, Modulatoren der nuklearen Hormonrezeptorfunktion |
US6953679B2 (en) | 2000-09-19 | 2005-10-11 | Bristol-Myers Squibb Company | Method for the preparation of fused heterocyclic succinimide compounds and analogs thereof |
US20040087548A1 (en) | 2001-02-27 | 2004-05-06 | Salvati Mark E. | Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function |
AU2002259147A1 (en) | 2001-05-08 | 2002-11-18 | Schering Corporation | Use of neurokinin receptor antagonists to treat androgen-dependent diseases |
AU2002322493A1 (en) * | 2001-07-10 | 2003-01-29 | Ams Research Corporation | Surgical kit for treating prostate tissue |
MY141661A (en) | 2001-09-06 | 2010-05-31 | Schering Corp | 17b-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases |
US6969718B2 (en) | 2001-10-17 | 2005-11-29 | Schering Corporation | 17-β hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases |
HUP0500096A3 (en) | 2001-12-19 | 2012-08-28 | Bristol Myers Squibb Co | Fused heterocyclic compounds and analogs thereof: modulators of nuclear hormone receptor function, process for producing them and pharmaceutical compositions containing them |
AU2003290799A1 (en) | 2002-11-18 | 2004-06-15 | Schering Corporation | 17beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases |
MXPA05006485A (es) | 2002-12-17 | 2005-08-26 | Schering Corp | Inhibidores de la 17 beta-hidroxiesteroide deshidrogenasa tipo 3 para el tratamiento de enfermedades dependientes de androgeno. |
US20060258628A1 (en) * | 2004-07-20 | 2006-11-16 | Steiner Mitchell S | Compositions comprising 5-alpha reductase inhibitors, and SARMs and methods of use thereof |
CN106038572A (zh) | 2004-10-20 | 2016-10-26 | 恩多研究公司 | 性甾体前体单独或与选择性雌激素受体调节剂联合用于预防和治疗绝经后女性的性功能障碍 |
GB0513702D0 (en) | 2005-07-04 | 2005-08-10 | Sterix Ltd | Compound |
EP3510959B1 (de) * | 2007-01-02 | 2021-03-03 | AquaBeam LLC | Minimalinvasive vorrichtungen zur behandlung von prostataerkrankungen |
US9232959B2 (en) | 2007-01-02 | 2016-01-12 | Aquabeam, Llc | Multi fluid tissue resection methods and devices |
US9284345B2 (en) | 2007-04-12 | 2016-03-15 | Endorecherche, Inc. | 17alpha-substituted steroids as systemic antiandrogens and selective androgen receptor modulators |
GB0708376D0 (en) | 2007-05-01 | 2007-06-06 | Alligator Bioscience Ab | Novel polypeptides and uses thereof |
US8268806B2 (en) | 2007-08-10 | 2012-09-18 | Endorecherche, Inc. | Pharmaceutical compositions |
GB0722779D0 (en) | 2007-11-20 | 2008-01-02 | Sterix Ltd | Compound |
EP2259742B1 (de) | 2008-03-06 | 2020-01-01 | AquaBeam LLC | Gewebeablation und kauterisation mit in einem flüssigkeitsstrom getragener optischer energie |
US9848904B2 (en) | 2009-03-06 | 2017-12-26 | Procept Biorobotics Corporation | Tissue resection and treatment with shedding pulses |
US10524822B2 (en) | 2009-03-06 | 2020-01-07 | Procept Biorobotics Corporation | Image-guided eye surgery apparatus |
EP3351196A1 (de) | 2012-02-29 | 2018-07-25 | Procept Biorobotics Corporation | Automatisierte bildgeführte geweberesektion und behandlung |
ES2681023T3 (es) * | 2012-02-29 | 2018-09-11 | Repros Therapeutics Inc. | Terapia de combinación para tratar el déficit de andrógenos |
CN109965976B (zh) | 2013-09-06 | 2022-05-31 | 普罗赛普特生物机器人公司 | 利用致脱脉冲的用于消融组织的装置 |
EP4070744A1 (de) | 2014-06-30 | 2022-10-12 | PROCEPT BioRobotics Corporation | Vorrichtungen für flüssigkeitsstrahlgeweberesektion und kaltkoagulation (aquablation) |
EP3188662A4 (de) | 2014-09-05 | 2018-05-23 | Procept Biorobotics Corporation | Arztkontrollierte geweberesektion mit integriertem behandlungsmapping von zielorganbildern |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4329364A (en) * | 1974-09-11 | 1982-05-11 | Schering Corporation | Antiandrogenic agents and methods for the treatment of androgen dependent disease states |
US4039669A (en) * | 1975-08-01 | 1977-08-02 | Sterling Drug Inc. | Composition for topical application and use thereof |
US4087461A (en) * | 1976-02-26 | 1978-05-02 | The Johns Hopkins University | Anti-androgenic steroids |
DE2817157A1 (de) * | 1978-04-17 | 1979-10-25 | Schering Ag | Verwendung von antioestrogenen und antigonadotrop wirkenden antiandrogenen zur prophylaxe und therapie der prostatahyperplasie |
US4235893A (en) * | 1978-05-08 | 1980-11-25 | Brodie Angela M | Ester derivatives of 4-hydroxy-4-androstene-3,17-dione and a method for inhibiting estrogen biosynthesis |
FR2465486A1 (fr) * | 1979-09-21 | 1981-03-27 | Roussel Uclaf | Nouvelle application utilisant la lh-rh ou des agonistes |
US4474813A (en) * | 1980-10-24 | 1984-10-02 | Schering Corporation | Pharmaceutical preparations comprising flutamide |
DE3121152A1 (de) * | 1981-05-22 | 1982-12-09 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | "verwendung der kombination eines aromatase-hemmers mit einem antiandrogen zur prophylaxe und therapie der prostatahyperplasie" |
DE3121153A1 (de) * | 1981-05-22 | 1982-12-09 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | "verwendung von aromatase-hemmern zur prophylaxe und therapie der prostatahyperplasie" |
US4347363A (en) * | 1981-09-17 | 1982-08-31 | Sterling Drug Inc. | Process for preparing 1,2-dihydro-6-methyl-2-oxo-5-(pyridinyl)nicotinonitriles |
DE3339295A1 (de) * | 1982-11-15 | 1984-05-17 | Schering AG, 1000 Berlin und 4709 Bergkamen | 4-hydroxy- und 4-acyloxy-4-androsten-3,17-dione zur verwendung bei der prophylaxe und therapie der prostatahyperplasie und diese enthaltende mittel fuer derartige verwendung |
GR79447B (de) * | 1982-12-31 | 1984-10-30 | Mortimer Christopher H Dr | |
DE3323321A1 (de) * | 1983-06-24 | 1985-01-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Prophylaxe und therapie von koronaren herzkrankheiten durch senkung des oestrogenspiegels |
JPH0745382B2 (ja) * | 1983-12-12 | 1995-05-17 | カスジンスキ−,エドウイン ジ−. | 毛の生長の改良 |
US4684635A (en) * | 1984-05-11 | 1987-08-04 | Norman Orentreich | Compositions and methods for inhibiting the action of androgens |
US5053403A (en) * | 1984-05-11 | 1991-10-01 | Norman Orentreich | Methods for treatment of male-pattern baldness |
US4659695A (en) * | 1985-02-08 | 1987-04-21 | Fernand Labrie | Method of treatment of prostate cancer |
DE3590389T1 (de) * | 1984-08-02 | 1986-08-28 | Schering Corp., Kenilworth, N.J. | Pharmazeutische Zusammensetzung für eine Kombinationstherapie hormon-abhängiger Cancer |
ATE43499T1 (de) * | 1984-10-10 | 1989-06-15 | Ile De France | Synergistische empfaengnisverhuetende mischung. |
GB8503940D0 (en) * | 1985-02-15 | 1985-03-20 | Erba Farmitalia | 4-substituted androstendione derivatives |
GB8505862D0 (en) * | 1985-03-07 | 1985-04-11 | Erba Farmitalia | Steroidic 5alpha-reductase inhibitors |
DE3607651A1 (de) * | 1986-03-06 | 1987-09-10 | Schering Ag | Kombination von aromatasehemmer und testosteron-5(alpha)-reduktase-hemmer |
HU203667B (en) * | 1986-12-11 | 1991-09-30 | Roussel Uclaf | Process for producing synergetic zootechnical compositions containing three components |
US4888336A (en) * | 1987-01-28 | 1989-12-19 | Smithkline Beckman Corporation | Steroid 5-alpha-reductase inhibitors |
EP0285383B1 (de) * | 1987-04-03 | 1994-03-16 | Merck & Co. Inc. | Behandlung von Prostatacarcinoma mit 17-beta-n-monosubstituierten-Carbamoyl-4-aza-5-alpha-Androst-1-en-3-onen |
US4895715A (en) * | 1988-04-14 | 1990-01-23 | Schering Corporation | Method of treating gynecomastia |
-
1990
- 1990-07-05 AT AT99106510T patent/ATE269066T1/de not_active IP Right Cessation
- 1990-07-05 HU HU9200047A patent/HU223662B1/hu active IP Right Grant
- 1990-07-05 ES ES90909598T patent/ES2133270T3/es not_active Expired - Lifetime
- 1990-07-05 DE DE69033020T patent/DE69033020T2/de not_active Expired - Lifetime
- 1990-07-05 AT AT90909598T patent/ATE177949T1/de not_active IP Right Cessation
- 1990-07-05 CA CA002062973A patent/CA2062973C/en not_active Expired - Lifetime
- 1990-07-05 EP EP98104849A patent/EP0857487A3/de not_active Withdrawn
- 1990-07-05 EP EP90909598A patent/EP0480950B1/de not_active Expired - Lifetime
- 1990-07-05 EP EP99106510A patent/EP0943328B1/de not_active Expired - Lifetime
- 1990-07-05 KR KR1019920700026A patent/KR920703063A/ko not_active Application Discontinuation
- 1990-07-05 WO PCT/CA1990/000210 patent/WO1991000731A1/en active IP Right Grant
- 1990-07-05 AU AU58545/90A patent/AU643445B2/en not_active Expired
- 1990-07-05 DK DK99106510T patent/DK0943328T3/da active
- 1990-07-05 DE DE69034148T patent/DE69034148T2/de not_active Expired - Lifetime
- 1990-07-05 ES ES99106510T patent/ES2222633T3/es not_active Expired - Lifetime
- 1990-07-05 JP JP50926290A patent/JP3332377B2/ja not_active Expired - Lifetime
- 1990-07-05 DK DK90909598T patent/DK0480950T3/da active
- 1990-07-06 ZA ZA905312A patent/ZA905312B/xx unknown
- 1990-07-06 IL IL9499090A patent/IL94990A/xx active IP Right Grant
- 1990-07-06 IE IE245990A patent/IE902459A1/en not_active IP Right Cessation
- 1990-07-06 IE IE19990530A patent/IE990530A1/en not_active IP Right Cessation
- 1990-07-07 MY MYPI90001141A patent/MY106484A/en unknown
- 1990-07-09 NZ NZ234414A patent/NZ234414A/xx unknown
-
1993
- 1993-12-03 AU AU52174/93A patent/AU668434B2/en not_active Expired
-
1995
- 1995-06-07 US US08/476,933 patent/US5817649A/en not_active Expired - Fee Related
-
2001
- 2001-06-12 JP JP2001177144A patent/JP2001354590A/ja active Pending
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Legal Events
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UEP | Publication of translation of european patent specification |
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EELA | Cancelled due to lapse of time |