ATE26447T1 - Verfahren zur herstellung von penicillansaeure-1,1-dioxiden und deren derivaten. - Google Patents

Verfahren zur herstellung von penicillansaeure-1,1-dioxiden und deren derivaten.

Info

Publication number
ATE26447T1
ATE26447T1 AT83200542T AT83200542T ATE26447T1 AT E26447 T1 ATE26447 T1 AT E26447T1 AT 83200542 T AT83200542 T AT 83200542T AT 83200542 T AT83200542 T AT 83200542T AT E26447 T1 ATE26447 T1 AT E26447T1
Authority
AT
Austria
Prior art keywords
dioxides
derivatives
preparation
acid
penicillan
Prior art date
Application number
AT83200542T
Other languages
English (en)
Inventor
Peter Wolfgang Henniger
Der Drift Johannes Karel Van
Jagdish Chander Kapur
Herman Pieter Fasel
Original Assignee
Gist Brocades Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv
Application granted granted Critical
Publication of ATE26447T1 publication Critical patent/ATE26447T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
AT83200542T 1982-04-19 1983-04-15 Verfahren zur herstellung von penicillansaeure-1,1-dioxiden und deren derivaten. ATE26447T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8211301 1982-04-19
EP83200542A EP0092286B1 (de) 1982-04-19 1983-04-15 Verfahren zur Herstellung von Penicillansäure-1,1-Dioxiden und deren Derivaten

Publications (1)

Publication Number Publication Date
ATE26447T1 true ATE26447T1 (de) 1987-04-15

Family

ID=10529780

Family Applications (2)

Application Number Title Priority Date Filing Date
AT83200541T ATE26982T1 (de) 1982-04-19 1983-04-15 Herstellung von 6-alpha-bromo- und/oder 6,6dibromo-penicillansaeure 1,1-dioxiden.
AT83200542T ATE26447T1 (de) 1982-04-19 1983-04-15 Verfahren zur herstellung von penicillansaeure-1,1-dioxiden und deren derivaten.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT83200541T ATE26982T1 (de) 1982-04-19 1983-04-15 Herstellung von 6-alpha-bromo- und/oder 6,6dibromo-penicillansaeure 1,1-dioxiden.

Country Status (14)

Country Link
US (2) US4528135A (de)
EP (2) EP0092286B1 (de)
JP (3) JPS58201788A (de)
KR (2) KR870000310B1 (de)
AT (2) ATE26982T1 (de)
CA (2) CA1216842A (de)
DE (2) DE3370799D1 (de)
DK (3) DK161891C (de)
ES (3) ES8405019A1 (de)
FI (2) FI78298C (de)
GR (2) GR77456B (de)
IE (2) IE54522B1 (de)
NO (2) NO159657C (de)
PT (2) PT76527B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468351A (en) * 1983-06-06 1984-08-28 Pfizer Inc. Process for debromination of dibromopenicillanic acid and derivatives
EP0139047A1 (de) * 1983-10-18 1985-05-02 Gist-Brocades N.V. Verfahren zur Herstellung von 6,6-Dibromopenicillansäure-1,1-Dioxyd
EP0139048A1 (de) * 1983-10-18 1985-05-02 Gist-Brocades N.V. Verfahren zur Dehalogenierung von 6,6-Dibromopenicillansäure-1,1-Dioxyd
US4760058A (en) * 1984-08-29 1988-07-26 Farmitalia Carlo Erba S.P.A. Penam derivatives
ATE77821T1 (de) * 1986-04-10 1992-07-15 Leo Pharm Prod Ltd Verfahren zur herstellung von penicillansaeurederivaten.
JPS62249988A (ja) * 1986-04-22 1987-10-30 Taiho Yakuhin Kogyo Kk ２β−ハロゲノメチル−２α−メチルペナム−３α−カルボン酸誘導体の製造法
AR247212A1 (es) * 1991-09-13 1994-11-30 Bago Sa Labor Procedimiento de preparacion de acido 1,1-dioxo penicilanico, sus sales y esteres.
ES2039299B1 (es) * 1991-10-04 1994-05-16 Asturpharma S A Procedimiento de obtencion de esteres de acido 1,1-dioxopenicilanico y sus sales.
FR2706896B1 (de) * 1993-06-23 1996-04-12 Caillot Jean Luc
ATE288438T1 (de) * 1999-03-03 2005-02-15 Astur Pharma Sa Verfahren zur herstellung von dioxopenicillansäurederivaten
CN101768035B (zh) * 2009-01-05 2013-11-27 浙江华海药业股份有限公司 一种制备以及回收芳香甲基联苯化合物的方法
CN104910184B (zh) * 2015-04-27 2017-03-29 齐鲁天和惠世制药有限公司 一种6,6‑二溴青霉烷酸的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4164497A (en) * 1972-10-20 1979-08-14 Fujisawa Pharmaceutical Co., Ltd. 2-Substituted penam derivatives
IN149747B (de) * 1977-06-07 1982-04-03 Pfizer
DK155942C (da) * 1977-12-23 1989-10-23 Pfizer Analogifremgangsmaade til fremstilling af 6-aminopenicillansyre-1,1-dioxid og fysiologisk acceptable syreadditions- og basesalte deraf.
SE449103B (sv) * 1979-03-05 1987-04-06 Pfizer Sett att framstella penicillansyra-1,1-dioxid samt estrar derav
US4432970A (en) * 1979-11-23 1984-02-21 Pfizer Inc. 6-beta-Halopenicillanic acid 1,1-dioxides as beta-lactamase inhibitors
NL7908867A (nl) * 1979-12-10 1981-07-01 Gist Brocades Nv Werkwijze voor het bereiden van 6-aminopenicillaanzuur- -1,1-dioxide en zijn zouten.
US4419284A (en) * 1981-03-23 1983-12-06 Pfizer Inc. Preparation of halomethyl esters (and related esters) of penicillanic acid 1,1-dioxide
US4444687A (en) * 1981-06-08 1984-04-24 Bristol-Myers Company 2β-Chloromethyl-2α-methylpenam-3α-carboxylic acid sulfone methylene diol mixed esters
US4360463A (en) * 1981-09-02 1982-11-23 Pfizer Inc. Pure 6,6-diiodopenicillanic acid and process for its preparation

Also Published As

Publication number Publication date
FI80038C (fi) 1990-04-10
ES521426A0 (es) 1984-05-16
NO831359L (no) 1983-10-20
DK169183A (da) 1983-10-20
ES8500621A1 (es) 1984-11-01
DK169083D0 (da) 1983-04-18
DK161891C (da) 1992-02-03
DK169183D0 (da) 1983-04-18
FI80038B (fi) 1989-12-29
IE54536B1 (en) 1989-11-08
JPH045035B2 (de) 1992-01-30
DK165295B (da) 1992-11-02
DE3371338D1 (de) 1987-06-11
NO159657C (no) 1989-01-25
DK165974B (da) 1993-02-22
FI78298B (fi) 1989-03-31
ATE26982T1 (de) 1987-05-15
IE54522B1 (en) 1989-11-08
GR79249B (de) 1984-10-22
JPS58201788A (ja) 1983-11-24
PT76527B (en) 1985-12-09
US4619786A (en) 1986-10-28
FI831300L (fi) 1983-10-20
EP0093465B1 (de) 1987-05-06
FI831300A0 (fi) 1983-04-18
CA1218055A (en) 1987-02-17
KR870000311B1 (ko) 1987-02-26
DE3370799D1 (en) 1987-05-14
NO831358L (no) 1983-10-20
JPS6354376A (ja) 1988-03-08
EP0093465A2 (de) 1983-11-09
NO161565B (no) 1989-05-22
IE830868L (en) 1983-10-19
KR840008368A (ko) 1984-12-14
NO159657B (no) 1988-10-17
ES8505688A1 (es) 1985-06-16
DK161891B (da) 1991-08-26
FI831301L (fi) 1983-10-20
DK165295C (da) 1993-03-22
EP0092286B1 (de) 1987-04-08
KR840004435A (ko) 1984-10-15
FI831301A0 (fi) 1983-04-18
PT76526B (en) 1986-01-21
EP0092286A3 (en) 1983-11-30
ES521425A0 (es) 1984-11-01
DK169083A (da) 1983-10-20
DK181691D0 (da) 1991-11-04
IE830869L (en) 1983-10-19
KR870000310B1 (ko) 1987-02-26
US4528135A (en) 1985-07-09
DK181691A (da) 1991-11-04
NO161565C (no) 1989-08-30
PT76527A (en) 1983-05-01
GR77456B (de) 1984-09-24
ES8405019A1 (es) 1984-05-16
JPH0229678B2 (de) 1990-07-02
ES533883A0 (es) 1985-06-16
PT76526A (en) 1983-05-01
JPS58201787A (ja) 1983-11-24
EP0092286A2 (de) 1983-10-26
EP0093465A3 (en) 1983-12-07
DK165974C (da) 1993-08-16
FI78298C (fi) 1989-07-10
CA1216842A (en) 1987-01-20
JPH034078B2 (de) 1991-01-22

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee