ATE25974T1 - Acyl-substituierte derivate von 1,2,3,4tetrahydroisochinolin-3-carboxysaeuren, ihre salze, diese enthaltende arzneimittel und verfahren zu ihrer herstellung. - Google Patents

Acyl-substituierte derivate von 1,2,3,4tetrahydroisochinolin-3-carboxysaeuren, ihre salze, diese enthaltende arzneimittel und verfahren zu ihrer herstellung.

Info

Publication number
ATE25974T1
ATE25974T1 AT81304541T AT81304541T ATE25974T1 AT E25974 T1 ATE25974 T1 AT E25974T1 AT 81304541 T AT81304541 T AT 81304541T AT 81304541 T AT81304541 T AT 81304541T AT E25974 T1 ATE25974 T1 AT E25974T1
Authority
AT
Austria
Prior art keywords
salts
acyl
manufacture
carboxylic acids
substituted derivatives
Prior art date
Application number
AT81304541T
Other languages
English (en)
Inventor
Milton Louis Hoefle
Sylvester Klutchko
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26889329&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE25974(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of ATE25974T1 publication Critical patent/ATE25974T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT81304541T 1980-10-03 1981-10-01 Acyl-substituierte derivate von 1,2,3,4tetrahydroisochinolin-3-carboxysaeuren, ihre salze, diese enthaltende arzneimittel und verfahren zu ihrer herstellung. ATE25974T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19376780A 1980-10-03 1980-10-03
US06/236,397 US4344949A (en) 1980-10-03 1981-02-20 Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
EP81304541A EP0049605B1 (de) 1980-10-03 1981-10-01 Acyl-substituierte Derivate von 1,2,3,4-Tetrahydroisochinolin-3-carboxysäuren, ihre Salze, diese enthaltende Arzneimittel und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
ATE25974T1 true ATE25974T1 (de) 1987-04-15

Family

ID=26889329

Family Applications (2)

Application Number Title Priority Date Filing Date
AT81304541T ATE25974T1 (de) 1980-10-03 1981-10-01 Acyl-substituierte derivate von 1,2,3,4tetrahydroisochinolin-3-carboxysaeuren, ihre salze, diese enthaltende arzneimittel und verfahren zu ihrer herstellung.
AT83102092T ATE26120T1 (de) 1980-10-03 1981-10-01 Substituierte acyl-derivate von 1,2,3,4tetrahydro-6,7-dimethoxy-3-isoquinolincarbons|ure.

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT83102092T ATE26120T1 (de) 1980-10-03 1981-10-01 Substituierte acyl-derivate von 1,2,3,4tetrahydro-6,7-dimethoxy-3-isoquinolincarbons|ure.

Country Status (23)

Country Link
US (1) US4344949A (de)
EP (2) EP0049605B1 (de)
JP (1) JPS5788164A (de)
KR (1) KR880001326B1 (de)
AT (2) ATE25974T1 (de)
AU (2) AU551239B2 (de)
CA (3) CA1341330C (de)
DD (1) DD201787A5 (de)
DE (3) DE3176029D1 (de)
DK (1) DK163120C (de)
ES (1) ES505960A0 (de)
FI (2) FI78690C (de)
GR (1) GR75353B (de)
HK (1) HK43389A (de)
IE (2) IE52666B1 (de)
IL (1) IL63806A (de)
LU (1) LU88321I2 (de)
MX (1) MX155144A (de)
MY (1) MY100440A (de)
NL (2) NL930077I2 (de)
NO (1) NO159017C (de)
PH (1) PH17740A (de)
SG (1) SG15689G (de)

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FI881985A0 (fi) 1988-04-27
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NO159017C (no) 1988-11-23
IE811566L (en) 1982-01-11
DE19575041I2 (de) 2001-11-22
US4344949A (en) 1982-08-17
IE52665B1 (en) 1988-01-20
EP0049605B1 (de) 1987-03-18
IL63806A (en) 1985-02-28
EP0096157A3 (en) 1984-09-12
ATE26120T1 (de) 1987-04-15
AU563683C (en) 2001-12-20
DE3176029D1 (en) 1987-04-30
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SG15689G (en) 1989-06-09
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FI78690B (fi) 1989-05-31
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FI881985A7 (fi) 1988-04-27
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DK163120C (da) 1992-06-15
EP0096157B1 (de) 1987-03-25
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