ATE256146T1 - Klonierung und verwendung des lsr-rezeptors - Google Patents

Klonierung und verwendung des lsr-rezeptors

Info

Publication number
ATE256146T1
ATE256146T1 AT98936611T AT98936611T ATE256146T1 AT E256146 T1 ATE256146 T1 AT E256146T1 AT 98936611 T AT98936611 T AT 98936611T AT 98936611 T AT98936611 T AT 98936611T AT E256146 T1 ATE256146 T1 AT E256146T1
Authority
AT
Austria
Prior art keywords
lsr
purified
cloning
ffa
isolated
Prior art date
Application number
AT98936611T
Other languages
English (en)
Inventor
Bernard Bihain
Lydie Bougueleret
Frances Yen-Potin
Original Assignee
Genset Sa
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9710088A external-priority patent/FR2767136B1/fr
Application filed by Genset Sa, Inst Nat Sante Rech Med filed Critical Genset Sa
Application granted granted Critical
Publication of ATE256146T1 publication Critical patent/ATE256146T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98936611T 1997-08-06 1998-08-06 Klonierung und verwendung des lsr-rezeptors ATE256146T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9710088A FR2767136B1 (fr) 1997-08-06 1997-08-06 Recepteur complexe lsr, activite, clonage, et applications au diagnostic, a la prevention et/ou au traitement de l'obesite et des risques ou complications associes
FR9805032A FR2767135B1 (fr) 1997-08-06 1998-04-22 Recepteur complexe lsr, activite, clonage, et application au diagnostic, a la prevention et/ou au traitement de d'obesite et des risques ou complications associes
PCT/IB1998/001257 WO1999007737A2 (fr) 1997-08-06 1998-08-06 Recepteur lsr, clonage et applications

Publications (1)

Publication Number Publication Date
ATE256146T1 true ATE256146T1 (de) 2003-12-15

Family

ID=26233732

Family Applications (3)

Application Number Title Priority Date Filing Date
AT98936610T ATE378354T1 (de) 1997-08-06 1998-08-06 Lipoprotein-regulierende arzneimittel
AT98936611T ATE256146T1 (de) 1997-08-06 1998-08-06 Klonierung und verwendung des lsr-rezeptors
AT07120518T ATE443721T1 (de) 1997-08-06 1998-08-06 Lipoprotein-regulierende medikamente

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT98936610T ATE378354T1 (de) 1997-08-06 1998-08-06 Lipoprotein-regulierende arzneimittel

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT07120518T ATE443721T1 (de) 1997-08-06 1998-08-06 Lipoprotein-regulierende medikamente

Country Status (13)

Country Link
US (8) US6635431B1 (de)
EP (4) EP1903057B1 (de)
JP (3) JP3726969B2 (de)
AT (3) ATE378354T1 (de)
AU (2) AU754942B2 (de)
CA (2) CA2298849A1 (de)
CY (1) CY1107808T1 (de)
DE (3) DE69841186D1 (de)
DK (2) DK1003783T3 (de)
ES (2) ES2210786T3 (de)
FR (1) FR2767135B1 (de)
PT (2) PT964870E (de)
WO (2) WO1999007737A2 (de)

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DE60041912D1 (de) 1999-02-10 2009-05-14 Serono Genetics Inst Sa Polymorphe marker des lsr-gens
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CA2440144A1 (en) * 2001-03-14 2002-09-19 Oklahoma Medical Research Foundation Methods for reducing fat by administration of adiponectin
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EP1414483A1 (de) * 2001-07-31 2004-05-06 Serono Genetics Institute S.A. Agonisten und antagonisten von moxifin zur behandlung von stoffwechselerkrankungen
US7276342B2 (en) * 2001-08-02 2007-10-02 Serono Genetics Institute S.A. Xobesin agonists and antagonists for the treatment of metabolic disorders
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AU2002339691A1 (en) * 2001-11-29 2003-06-10 Genset Agonists and antagonists of prolixin for the treatment of metabolic disorders
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DE60329000D1 (de) * 2002-05-24 2009-10-08 Japan Science & Tech Agency C-terminale globulardomäne von adiponectin zur behandlung von arteriosklerose
ATE478890T1 (de) * 2002-05-31 2010-09-15 Serono Genetics Inst Sa Homotrimerer, erweiterter globulärer kopf von obg3 und verwendungen davon
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US7276342B2 (en) * 2001-08-02 2007-10-02 Serono Genetics Institute S.A. Xobesin agonists and antagonists for the treatment of metabolic disorders
AU2002339691A1 (en) * 2001-11-29 2003-06-10 Genset Agonists and antagonists of prolixin for the treatment of metabolic disorders

Also Published As

Publication number Publication date
EP0964870A2 (de) 1999-12-22
EP1003783A2 (de) 2000-05-31
FR2767135A1 (fr) 1999-02-12
WO1999007736A2 (en) 1999-02-18
DE69841186D1 (de) 2009-11-05
WO1999007736A3 (en) 1999-05-20
DK1003783T3 (da) 2008-01-02
EP0964870B1 (de) 2003-12-10
WO1999007737A3 (fr) 1999-06-10
ES2210786T3 (es) 2004-07-01
JP2001512746A (ja) 2001-08-28
ATE443721T1 (de) 2009-10-15
DE69838720D1 (de) 2007-12-27
US20090263847A1 (en) 2009-10-22
US7919091B2 (en) 2011-04-05
EP1903057B1 (de) 2009-09-23
JP2005143508A (ja) 2005-06-09
EP1903057A3 (de) 2008-06-25
DK0964870T3 (da) 2004-03-08
US7291709B2 (en) 2007-11-06
US20040077051A1 (en) 2004-04-22
PT964870E (pt) 2004-02-27
US7220722B2 (en) 2007-05-22
FR2767135B1 (fr) 2002-07-12
AU745607C (en) 2002-08-29
DE69820419T2 (de) 2004-11-25
PT1003783E (pt) 2007-12-06
US6635431B1 (en) 2003-10-21
ES2296339T3 (es) 2008-04-16
DE69820419D1 (de) 2004-01-22
CA2274302A1 (fr) 1999-02-18
DE69838720T2 (de) 2008-10-30
EP1375516A3 (de) 2004-06-09
EP1903057A2 (de) 2008-03-26
US20080249009A1 (en) 2008-10-09
CY1107808T1 (el) 2013-06-19
US6946444B2 (en) 2005-09-20
EP1003783B1 (de) 2007-11-14
US20110165166A1 (en) 2011-07-07
ATE378354T1 (de) 2007-11-15
JP3726969B2 (ja) 2005-12-14
AU754942B2 (en) 2002-11-28
US20020151498A1 (en) 2002-10-17
AU8556398A (en) 1999-03-01
AU745607B2 (en) 2002-03-21
US6344441B1 (en) 2002-02-05
JP2001512492A (ja) 2001-08-21
WO1999007737A2 (fr) 1999-02-18
CA2298849A1 (en) 1999-02-18
AU8556498A (en) 1999-03-01
US20020165154A1 (en) 2002-11-07
EP1375516A2 (de) 2004-01-02

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