ATE248153T1 - Neue benzoxazole - Google Patents
Neue benzoxazoleInfo
- Publication number
- ATE248153T1 ATE248153T1 AT95940634T AT95940634T ATE248153T1 AT E248153 T1 ATE248153 T1 AT E248153T1 AT 95940634 T AT95940634 T AT 95940634T AT 95940634 T AT95940634 T AT 95940634T AT E248153 T1 ATE248153 T1 AT E248153T1
- Authority
- AT
- Austria
- Prior art keywords
- pde
- benzoxazoles
- new
- inhibition
- new benzoxazoles
- Prior art date
Links
- BCMCBBGGLRIHSE-UHFFFAOYSA-N 1,3-benzoxazole Chemical compound C1=CC=C2OC=NC2=C1 BCMCBBGGLRIHSE-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000005764 inhibitory process Effects 0.000 abstract 2
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 abstract 2
- 239000002587 phosphodiesterase IV inhibitor Substances 0.000 abstract 1
- HJORMJIFDVBMOB-UHFFFAOYSA-N rolipram Chemical compound COC1=CC=C(C2CC(=O)NC2)C=C1OC1CCCC1 HJORMJIFDVBMOB-UHFFFAOYSA-N 0.000 abstract 1
- 229950005741 rolipram Drugs 0.000 abstract 1
- 229960000278 theophylline Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D263/57—Aryl or substituted aryl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08321730 US5665737B1 (en) | 1994-10-12 | 1994-10-12 | Substituted benzoxazoles |
| US46709195A | 1995-06-06 | 1995-06-06 | |
| PCT/US1995/014399 WO1996011917A1 (en) | 1994-10-12 | 1995-10-11 | Novel benzoxazoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE248153T1 true ATE248153T1 (de) | 2003-09-15 |
Family
ID=26983104
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95940634T ATE248153T1 (de) | 1994-10-12 | 1995-10-11 | Neue benzoxazole |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0785927B1 (de) |
| KR (1) | KR100237962B1 (de) |
| AT (1) | ATE248153T1 (de) |
| AU (1) | AU699489B2 (de) |
| BG (1) | BG101422A (de) |
| CA (1) | CA2202273A1 (de) |
| DE (1) | DE69531623T2 (de) |
| FI (1) | FI971489A7 (de) |
| NO (1) | NO971684L (de) |
| PL (1) | PL319605A1 (de) |
| SK (1) | SK45497A3 (de) |
| WO (1) | WO1996011917A1 (de) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1283860B (de) * | 1963-03-08 | 1968-11-28 | Demag Ag | Metallurgisches Schuettelgefaess, insbesondere Konverter, zur Frischbehandlung eines Roheisenbades mittels Sauerstoffblaslanzen |
| US5591776A (en) * | 1994-06-24 | 1997-01-07 | Euro-Celtique, S.A. | Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV |
| CA2258728C (en) | 1996-06-19 | 2011-09-27 | Rhone Poulenc Rorer Limited | Substituted azabicylic compounds and their use as inhibitors of the production of tnf and cyclic amp phosphodiesterase |
| US5849774A (en) * | 1996-07-03 | 1998-12-15 | University Of Pittsburgh | Treatment of sepsis-induced acute renal failure |
| JP2001503443A (ja) | 1996-11-11 | 2001-03-13 | ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング | 新規イミダゾ―及びオキサゾロピリジン |
| HUP0000189A3 (en) | 1996-11-15 | 2002-01-28 | Darwin Discovery Ltd Milton Ro | Bicyclic aryl carboxamides pharmaceutical compositions containing them and their therapeutic use |
| US6383986B1 (en) | 1997-07-14 | 2002-05-07 | Basf Aktiengesellschaft | Substituted 2-(benzoaryl)pyridines |
| FR2766822B1 (fr) * | 1997-07-30 | 2001-02-23 | Adir | Nouveaux derives de benzimidazole, de benzoxazole et de benzothiazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| CA2331037A1 (en) * | 1998-05-05 | 1999-11-11 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Novel benzimidazoles and benzoxazoles |
| DE69916066T2 (de) * | 1998-07-06 | 2005-02-24 | Altana Pharma Ag | Neue benzoxazole mit pde-hemmender wirkung |
| AU2942000A (en) * | 1999-03-11 | 2000-09-28 | Banyu Pharmaceutical Co., Ltd. | Novel piperidine derivatives |
| PL200923B1 (pl) | 1999-08-21 | 2009-02-27 | Nycomed Gmbh | Lek zawierający inhibitor PDE w połączeniu z agonistą receptoraß₂ -adrenergicznego oraz zastosowanie połączenia roflumilastu i salmeterolu |
| CO5261573A1 (es) | 1999-11-19 | 2003-03-31 | Novartis Ag | Derivados de benzoxa y bezotiazol, compuesto y composicion farmaceutica que los contiene y proceso para la preparacion de la mencionada composicion |
| EP1160247A1 (de) * | 2000-05-08 | 2001-12-05 | Euro-Celtique S.A. | 6,5 kondensierten, aromatischen, polycyclischen verbindung mit phosphodiesterase iv hemmender aktivität |
| WO2003045929A1 (en) * | 2001-11-26 | 2003-06-05 | Takeda Chemical Industries, Ltd. | Bicyclic derivative, process for producing the same, and use |
| AU2002353739A1 (en) * | 2001-11-28 | 2003-06-10 | Astrazeneca Ab | Therapeutic compounds |
| AU2002365892A1 (en) * | 2001-11-30 | 2003-06-17 | Merck & Co., Inc. | Metabotropic glutamate receptor-5 modulators |
| US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| EP1599449A2 (de) | 2003-02-25 | 2005-11-30 | TopoTarget UK Limited | Bicyclische heteroaromatische carbaminsäurederivate mit hdac hemmender wirkung |
| JP2006522151A (ja) | 2003-04-01 | 2006-09-28 | アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ | 不妊症におけるホスホジエステラーゼ阻害剤 |
| ITTO20040125A1 (it) * | 2004-03-01 | 2004-06-01 | Rotta Research Lab | Nuove amidine eterocicliche inibitrici la produzione di ossido d'azoto (no) ad attivita' antinfiammatoria ed analgesica |
| WO2006032851A1 (en) | 2004-09-20 | 2006-03-30 | Biolipox Ab | Pyrazole compounds useful in the treatment of inflammation |
| DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
| EP1852108A1 (de) | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | Zusammensetzungen von DPP-IV-Inhibitoren |
| BRPI0711558A2 (pt) | 2006-05-04 | 2011-11-08 | Boeringer Ingelheim Internat Gmbh | polimorfos |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| NZ574028A (en) | 2006-07-05 | 2010-10-29 | Fibrotech Therapeutics Pty Ltd | Tranilast analogues (substituted cinnamoyl anthranilate compounds) for treatment of conditions associated with firbrosis |
| WO2008082003A1 (en) * | 2006-12-29 | 2008-07-10 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compounds having crf antagonistic activity |
| WO2008151257A2 (en) | 2007-06-04 | 2008-12-11 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| JP2010530418A (ja) * | 2007-06-20 | 2010-09-09 | メルク・シャープ・エンド・ドーム・コーポレイション | ベンゾオキサゾールアリールアミドから誘導されたｃｅｔｐ阻害剤 |
| JP2010530416A (ja) | 2007-06-20 | 2010-09-09 | メルク・シャープ・エンド・ドーム・コーポレイション | ベンゾオキサゾールアリールアミドから誘導されたｃｅｔｐ阻害剤 |
| CA2689523A1 (en) | 2007-06-20 | 2008-12-24 | Merck Sharp & Dohme Corp. | Cetp inhibitors derived from benzoxazole arylamides |
| PE20140960A1 (es) | 2008-04-03 | 2014-08-15 | Boehringer Ingelheim Int | Formulaciones que comprenden un inhibidor de dpp4 |
| ES2627848T3 (es) | 2008-06-04 | 2017-07-31 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
| ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
| UY32030A (es) | 2008-08-06 | 2010-03-26 | Boehringer Ingelheim Int | "tratamiento para diabetes en pacientes inapropiados para terapia con metformina" |
| BRPI0916997A2 (pt) | 2008-08-06 | 2020-12-15 | Boehringer Ingelheim International Gmbh | Inibidor de dpp-4 e seu uso |
| US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
| EP2382216A1 (de) | 2008-12-23 | 2011-11-02 | Boehringer Ingelheim International GmbH | Salzformen einer organischen verbindung |
| AR074990A1 (es) | 2009-01-07 | 2011-03-02 | Boehringer Ingelheim Int | Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina |
| EP2947073B1 (de) | 2009-10-22 | 2019-04-03 | Fibrotech Therapeutics Pty Ltd | Analoga von antifibriotischen mitteln mit kondensierten ringen |
| EA034869B1 (ru) | 2009-11-27 | 2020-03-31 | Бёрингер Ингельхайм Интернациональ Гмбх | Лечение генотипированных пациентов с диабетом ингибиторами дпп-4, такими как линаглиптин |
| MX341025B (es) | 2010-05-05 | 2016-08-04 | Boehringer Ingelheim Int Gmbh * | Terapia de combinacion. |
| PH12012502524A1 (en) | 2010-06-24 | 2014-02-10 | Boehringer Ingelheim Int | Diabetes therapy |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| US9034883B2 (en) | 2010-11-15 | 2015-05-19 | Boehringer Ingelheim International Gmbh | Vasoprotective and cardioprotective antidiabetic therapy |
| MX357121B (es) | 2011-03-01 | 2018-06-27 | Synergy Pharmaceuticals Inc Star | Proceso de preparacion de agonistas c de guanilato ciclasa. |
| EP3517539B1 (de) | 2011-07-15 | 2022-12-14 | Boehringer Ingelheim International GmbH | Substituiertes dimeres chinazolinderivat, dessen herstellung und dessen verwendung in pharmazeutischen zusammensetzungen zur behandlung von diabetes typ i und ii |
| US9555001B2 (en) | 2012-03-07 | 2017-01-31 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition and uses thereof |
| US20130303554A1 (en) | 2012-05-14 | 2013-11-14 | Boehringer Ingelheim International Gmbh | Use of a dpp-4 inhibitor in sirs and/or sepsis |
| JP6224084B2 (ja) | 2012-05-14 | 2017-11-01 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 糸球体上皮細胞関連障害及び／又はネフローゼ症候群の治療に用いるｄｐｐ−４阻害薬としてのキサンチン誘導体 |
| WO2013174767A1 (en) | 2012-05-24 | 2013-11-28 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference |
| EP2958577A2 (de) | 2013-02-25 | 2015-12-30 | Synergy Pharmaceuticals Inc. | Guanylat-cyclase-rezeptoragonisten zur verwendung bei der darmreinigung |
| US9708367B2 (en) | 2013-03-15 | 2017-07-18 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
| EP2968439A2 (de) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Zusammensetzungen zur behandlung von magen-darm-störungen |
| PL3004138T3 (pl) | 2013-06-05 | 2024-07-29 | Bausch Health Ireland Limited | Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie |
| CA2920856C (en) | 2013-08-09 | 2026-03-03 | Ardelyx, Inc. | Ph modulating compounds for inhibiting gastrointestinal phosphate uptake |
| US9526728B2 (en) | 2014-02-28 | 2016-12-27 | Boehringer Ingelheim International Gmbh | Medical use of a DPP-4 inhibitor |
| CN109310697A (zh) | 2016-06-10 | 2019-02-05 | 勃林格殷格翰国际有限公司 | 利格列汀和二甲双胍的组合 |
| EP3577103A1 (de) | 2017-02-03 | 2019-12-11 | Certa Therapeutics Pty Ltd. | Antifibrotische verbindungen |
| JP2022533251A (ja) | 2019-05-21 | 2022-07-21 | アルデリックス， インコーポレイテッド | 患者において血清リン酸塩を低下させるための組み合わせ |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2320654A (en) * | 1940-08-08 | 1943-06-01 | Riester Oskar | Sensitization of photographic emulsions |
| US3136771A (en) * | 1962-03-09 | 1964-06-09 | Ciba Ltd | Bis-(2-benzoxazolyl) furylmethy-pyridinium chloride |
| US3491091A (en) * | 1962-03-28 | 1970-01-20 | Boehringer & Soehne Gmbh | 5-nitrofuran derivatives |
| US3470164A (en) * | 1962-05-04 | 1969-09-30 | Dainippon Pharmaceutical Co | 2-(2-(5-nitrofuryl)-vinyl)-azoles and process for producing thereof |
| US3494919A (en) * | 1964-07-30 | 1970-02-10 | American Cyanamid Co | Preparation of styryloxazole compounds |
| CH465959A (de) * | 1966-11-30 | 1969-01-15 | Ciba Geigy | Gebrauchsfertiges Mittel zur Bekämpfung von schädlichen Mikroorganismen auf textilem Material |
| CH542853A (de) * | 1967-07-26 | 1973-10-15 | Agripat Sa | Verfahren zur Herstellung neuer Isothiocyano-benzazol-Derivate |
| US3541100A (en) * | 1967-12-14 | 1970-11-17 | American Cyanamid Co | Benzheteroazolo(2,3-a)isoquinolium salts |
| US3669979A (en) * | 1967-12-14 | 1972-06-13 | Gaf Corp | Novel process for the production of 2-benzothiazolyl-phenol and derivatives thereof employing phosphorus trichloride as a catalyst |
| US3491106A (en) * | 1967-12-15 | 1970-01-20 | Gaf Corp | Sodium 3-(2-benzothiazolyl) - 4-hydroxy-benzenesulfonates and analogues thereof |
| CH516339A (de) * | 1969-03-03 | 1971-12-15 | Ciba Geigy Ag | Verwendung von Azolverbindungen als Antioxydantien |
| US3647812A (en) * | 1969-04-22 | 1972-03-07 | Richard F Smith | Halogenated 2(2'-hydroxyphenyl benzothiazoles |
| US3574218A (en) * | 1969-08-11 | 1971-04-06 | Egyt Gyogyszervegyeszeti Gyar | 2-aryl- or aralkyl-substituted benzazole derivatives |
| US3666769A (en) * | 1969-10-09 | 1972-05-30 | Du Pont | Thermally stable 2-perfluoro-substituted benzothiazoles |
| US3674781A (en) * | 1970-09-15 | 1972-07-04 | Hoechst Ag | Optical brighteners of the benzoxazole series |
| US3895028A (en) * | 1972-09-12 | 1975-07-15 | Tokyo Tanabe Co | Alpha-(2-phenylbenzothiazol-5-yl)propionic acid |
| US4025637A (en) * | 1973-10-23 | 1977-05-24 | Lilly Industries, Ltd. | 2,5 OR 2,6 Disubstituted benzoxazoles |
| US4025636A (en) * | 1973-10-23 | 1977-05-24 | Lilly Industries, Ltd. | 2-(Optionally substituted)phenyl-5 or 6-substituted benzoxazoles |
| US4020165A (en) * | 1975-08-20 | 1977-04-26 | Uniroyal Inc. | Control of acarids using certain benzothiazoles or benzothiazolines |
| LU76467A1 (de) * | 1976-12-23 | 1978-07-10 | ||
| JPS5721375A (en) * | 1980-07-14 | 1982-02-04 | Yamanouchi Pharmaceut Co Ltd | 2,6-di-tert-butyl-4-heterocyclic substituted phenolic derivative and its preparation |
| US4416892A (en) * | 1981-04-23 | 1983-11-22 | Lilly Industries Limited | Method of treating hypersensitivity disease with benzoxazole derivatives |
| JPS615071A (ja) * | 1984-06-15 | 1986-01-10 | Fuji Photo Film Co Ltd | ベンゾオキサゾ−ル誘導体 |
| IT1177017B (it) * | 1984-10-22 | 1987-08-26 | Ravizza Spa | Processo per la preparazione dell'acido 2(4-flurofenil)alfa-metil-5-benzox azoloacetico |
| US4732978A (en) * | 1985-10-03 | 1988-03-22 | American Home Products Corporation | Novel substituted naphthyloxymethyl quinoline derivatives as anti-inflammatory and antiallergy agents |
| JPH0670025B2 (ja) * | 1987-08-07 | 1994-09-07 | 鐘紡株式会社 | ベンゾチアゾ−ル誘導体および該化合物を有効成分とする抗リウマチ剤 |
| DE3808914A1 (de) * | 1988-03-17 | 1989-10-05 | Bayer Ag | Neue 2-aryl-benzoxazole und neue 2'-hydroxybenzanilide |
| JPH03173874A (ja) * | 1989-09-29 | 1991-07-29 | Mitsubishi Kasei Corp | 新規複素環化合物 |
| US5190942A (en) * | 1991-04-22 | 1993-03-02 | E. R. Squibb & Sons, Inc. | Benzoxazole and related heterocyclic substituted imidazole and benzimidazole derivatives |
| US5322847A (en) * | 1992-11-05 | 1994-06-21 | Pfizer Inc. | Azabenzimidazoles in the treatment of asthma, arthritis and related diseases |
-
1995
- 1995-10-11 AU AU42317/96A patent/AU699489B2/en not_active Ceased
- 1995-10-11 EP EP95940634A patent/EP0785927B1/de not_active Expired - Lifetime
- 1995-10-11 PL PL95319605A patent/PL319605A1/xx unknown
- 1995-10-11 DE DE69531623T patent/DE69531623T2/de not_active Expired - Fee Related
- 1995-10-11 SK SK454-97A patent/SK45497A3/sk unknown
- 1995-10-11 AT AT95940634T patent/ATE248153T1/de not_active IP Right Cessation
- 1995-10-11 WO PCT/US1995/014399 patent/WO1996011917A1/en not_active Ceased
- 1995-10-11 KR KR1019970702390A patent/KR100237962B1/ko not_active Expired - Fee Related
- 1995-10-11 CA CA002202273A patent/CA2202273A1/en not_active Abandoned
- 1995-10-11 FI FI971489A patent/FI971489A7/fi unknown
-
1997
- 1997-04-11 NO NO971684A patent/NO971684L/no not_active Application Discontinuation
- 1997-04-18 BG BG101422A patent/BG101422A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0785927A1 (de) | 1997-07-30 |
| PL319605A1 (en) | 1997-08-18 |
| KR100237962B1 (ko) | 2000-02-01 |
| BG101422A (bg) | 1997-11-28 |
| EP0785927A4 (de) | 1997-12-29 |
| NO971684D0 (no) | 1997-04-11 |
| NO971684L (no) | 1997-06-12 |
| DE69531623T2 (de) | 2004-06-17 |
| DE69531623D1 (de) | 2003-10-02 |
| CA2202273A1 (en) | 1996-04-25 |
| AU4231796A (en) | 1996-05-06 |
| SK45497A3 (en) | 1997-10-08 |
| AU699489B2 (en) | 1998-12-03 |
| FI971489A0 (fi) | 1997-04-10 |
| WO1996011917A1 (en) | 1996-04-25 |
| FI971489L (fi) | 1997-06-05 |
| EP0785927B1 (de) | 2003-08-27 |
| FI971489A7 (fi) | 1997-06-05 |
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